JP2010540462A5 - - Google Patents

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Publication number
JP2010540462A5
JP2010540462A5 JP2010526066A JP2010526066A JP2010540462A5 JP 2010540462 A5 JP2010540462 A5 JP 2010540462A5 JP 2010526066 A JP2010526066 A JP 2010526066A JP 2010526066 A JP2010526066 A JP 2010526066A JP 2010540462 A5 JP2010540462 A5 JP 2010540462A5
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Japan
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substituted
unsubstituted
hydroxy
carbonyl
alkyl
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JP2010526066A
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English (en)
Japanese (ja)
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JP5055432B2 (ja
JP2010540462A (ja
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Priority claimed from PCT/US2008/077537 external-priority patent/WO2009042694A1/en
Publication of JP2010540462A publication Critical patent/JP2010540462A/ja
Publication of JP2010540462A5 publication Critical patent/JP2010540462A5/ja
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Publication of JP5055432B2 publication Critical patent/JP5055432B2/ja
Expired - Fee Related legal-status Critical Current
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JP2010526066A 2007-09-24 2008-09-24 治療のためのβ−セクレターゼ阻害剤としての（３−ヒドロキシ−４−アミノブタン−２−イル）−３−（２−チアゾール−２−イル−ピロリジン−１−カルボニル）ベンズアミド誘導体及び関連する化合物 Expired - Fee Related JP5055432B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97479307P 2007-09-24 2007-09-24
US60/974,793 2007-09-24
PCT/US2008/077537 WO2009042694A1 (en) 2007-09-24 2008-09-24 (3-hydroxy-4-amino-butan-2-yl) -3- (2-thiazol-2-yl-pyrrolidine-1-carbonyl) benzamide derivatives and related compounds as beta-secretase inhibitors for treating

Publications (3)

Publication Number Publication Date
JP2010540462A JP2010540462A (ja) 2010-12-24
JP2010540462A5 true JP2010540462A5 (en:Method) 2011-11-10
JP5055432B2 JP5055432B2 (ja) 2012-10-24

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010526066A Expired - Fee Related JP5055432B2 (ja) 2007-09-24 2008-09-24 治療のためのβ−セクレターゼ阻害剤としての（３−ヒドロキシ−４−アミノブタン−２−イル）−３−（２−チアゾール−２−イル−ピロリジン−１−カルボニル）ベンズアミド誘導体及び関連する化合物

Country Status (8)

Country Link
US (1) US8299267B2 (en:Method)
EP (1) EP2205596A1 (en:Method)
JP (1) JP5055432B2 (en:Method)
KR (1) KR20100059919A (en:Method)
CN (1) CN101868457B (en:Method)
CA (1) CA2699787A1 (en:Method)
MX (1) MX2010002938A (en:Method)
WO (1) WO2009042694A1 (en:Method)

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CN105669365B (zh) * 2016-03-04 2022-06-21 中国科学院上海有机化学研究所 含二氟烷基取代的芳基或杂芳基化合物、制备方法和应用
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CN110117237B (zh) * 2018-02-05 2024-02-02 中国科学院上海有机化学研究所 一种芳香腈或烯基腈类化合物的制备方法
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