JP2010538626A5 - - Google Patents
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- Publication number
- JP2010538626A5 JP2010538626A5 JP2010524414A JP2010524414A JP2010538626A5 JP 2010538626 A5 JP2010538626 A5 JP 2010538626A5 JP 2010524414 A JP2010524414 A JP 2010524414A JP 2010524414 A JP2010524414 A JP 2010524414A JP 2010538626 A5 JP2010538626 A5 JP 2010538626A5
- Authority
- JP
- Japan
- Prior art keywords
- iii
- plant
- plant cell
- nucleic acid
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 2
- 238000010353 genetic engineering Methods 0.000 claims 2
- 230000005017 genetic modification Effects 0.000 claims 2
- 235000013617 genetically modified food Nutrition 0.000 claims 2
- 102000002740 Glucosamine 6-Phosphate N-Acetyltransferase Human genes 0.000 claims 1
- 108010043841 Glucosamine 6-Phosphate N-Acetyltransferase Proteins 0.000 claims 1
- 102100012384 UAP1 Human genes 0.000 claims 1
- 108010061048 UDPacetylglucosamine pyrophosphorylase Proteins 0.000 claims 1
- 230000005714 functional activity Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000008929 regeneration Effects 0.000 claims 1
- 238000011069 regeneration method Methods 0.000 claims 1
Claims (1)
- 植物を産生するための方法であって、以下を含む
a)植物細胞の遺伝的改変、ここで遺伝子改変は以下の工程i〜iiiを含む
i)グルコサミノグリカン合成酵素の活性を有するタンパク質をコードする核酸分子の植物細胞中への導入
ii)グルコサミン6−リン酸アセチルトランスフェラーゼの活性を有するタンパク質をコードする核酸分子の植物細胞中への導入
iii)UDP−N−アセチル−グルコサミンピロホスホリラーゼの単機能性活性を有するタンパク質をコードする核酸分子の植物細胞中への導入
b)工程a)i及び/又はa)ii及び/又はa)iiiからの植物細胞からの植物の再生;
c)適宜、工程b)の植物を使用したさらなる植物の生成、
ここで工程a)i〜a)iiiは任意の順番で個々に行うことができ、又は、工程a)i〜a)iiiの任意の組み合わせを同時に行ってよく、適宜、工程a)i〜a)iiiの失われた外来核酸分子を、工程b)又はc)に従って得られた植物の植物細胞中に導入してよい。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07116174.9 | 2007-09-12 | ||
EP07116174A EP2036983A1 (de) | 2007-09-12 | 2007-09-12 | Pflanzen, die erhöhte Mengen an Glucosaminglycanen synthetisieren |
US99357507P | 2007-09-13 | 2007-09-13 | |
US60/993,575 | 2007-09-13 | ||
PCT/EP2008/007837 WO2009033752A1 (en) | 2007-09-12 | 2008-09-11 | Plants which synthesize increased amounts of glucosaminglycans |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2010538626A JP2010538626A (ja) | 2010-12-16 |
JP2010538626A5 true JP2010538626A5 (ja) | 2012-09-20 |
JP5529741B2 JP5529741B2 (ja) | 2014-06-25 |
Family
ID=39205122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010524414A Expired - Fee Related JP5529741B2 (ja) | 2007-09-12 | 2008-09-11 | 増加した量のグルコサミノグリカンを合成する植物 |
Country Status (9)
Country | Link |
---|---|
US (1) | US9150873B2 (ja) |
EP (2) | EP2036983A1 (ja) |
JP (1) | JP5529741B2 (ja) |
CN (1) | CN101855354B (ja) |
AR (1) | AR068623A1 (ja) |
AT (1) | ATE551425T1 (ja) |
AU (1) | AU2008297527B2 (ja) |
CA (1) | CA2698989C (ja) |
WO (1) | WO2009033752A1 (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1964924B1 (en) * | 2005-12-15 | 2015-09-30 | Seikagaku Corporation | Long-chain chondroitin sugar chain and method for producing the same and method for promoting synthesis of chondroitin |
CN106755022B (zh) * | 2015-11-25 | 2020-08-04 | 中国科学院大连化学物理研究所 | 乙酰葡萄糖胺磷酸变位酶AtAGM编码基因及其酶、制备、应用与酶活性检测方法 |
CN113528482B (zh) * | 2021-08-02 | 2024-02-06 | 山东大学 | 高活性肝素骨架合酶PmHS2突变体及其应用 |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4141973A (en) | 1975-10-17 | 1979-02-27 | Biotrics, Inc. | Ultrapure hyaluronic acid and the use thereof |
NL8300698A (nl) | 1983-02-24 | 1984-09-17 | Univ Leiden | Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten. |
NO161573C (no) | 1983-11-25 | 1989-08-30 | Miles Inc | Fremgangsmaate til fremstilling av hyaluronsyre. |
JPS60251898A (ja) | 1984-05-25 | 1985-12-12 | Shiseido Co Ltd | 醗酵法によるヒアルロン酸の製造方法 |
CN85100964A (zh) * | 1985-04-01 | 1988-02-17 | 赵凤源 | 树木多代嫁接繁殖法 |
CN1003347B (zh) * | 1985-04-27 | 1989-02-22 | 广西化工研究所 | 植物生长调节剂 |
US5565347A (en) | 1986-06-10 | 1996-10-15 | Calgene, Inc. | Transformation and foreign gene expression with plant species |
NO173355C (no) | 1987-03-03 | 1993-12-01 | Chugai Pharmaceutical Co Ltd | Fremgangsm}te og selektiv bestemmelse av en h!ymolekylvekts hyaluronsyre og reagenssett for utf!relse av fremgangsm}ten |
ES2074999T3 (es) | 1987-05-20 | 1995-10-01 | Ciba Geigy Ag | Plantas de zea mays y plantas de zea mays transgenicas regeneradas de protoplastos o celulas derivadas de protoplastos. |
US4897349A (en) | 1989-04-28 | 1990-01-30 | Medchem Products, Inc. | Biosynthesis of hyaluronic acid |
US7705215B1 (en) | 1990-04-17 | 2010-04-27 | Dekalb Genetics Corporation | Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof |
ATE173581T1 (de) | 1990-06-23 | 1998-12-15 | Hoechst Schering Agrevo Gmbh | Methode zur produktion einer kalluskultur von zea mays (l.) |
JPH05199877A (ja) | 1991-10-03 | 1993-08-10 | Sumitomo Chem Co Ltd | バレイショおよびイネの誘導型植物防御遺伝子の制御領域、その用途およびアッセイ法 |
US6455304B1 (en) | 1994-07-01 | 2002-09-24 | The Board Of Regents Of The University Of Oklahoma | Hyaluronate synthase gene and uses thereof |
IT1271001B (it) | 1994-07-26 | 1997-05-26 | Poli Ind Chimica Spa | Procedimento di preparazione di acido ialuronico mediante fermentazione con streptococcus |
DE19619918A1 (de) | 1996-05-17 | 1997-11-20 | Planttec Biotechnologie Gmbh | Nucleinsäuremoleküle codierend lösliche Stärkesynthasen aus Mais |
GB9702592D0 (en) | 1997-02-07 | 1997-03-26 | Danisco | Selection method |
US6369298B1 (en) | 1997-04-30 | 2002-04-09 | Pioneer Hi-Bred International, Inc. | Agrobacterium mediated transformation of sorghum |
US20030104601A1 (en) | 1999-04-01 | 2003-06-05 | Deangelis Paul L. | Chondroitin synthase gene and methods of making and using same |
US7094581B2 (en) | 1998-10-26 | 2006-08-22 | The Board Of Regents Of The University Of Oklahoma | Hyaluronan synthases and methods of making and using same |
JP2001060708A (ja) * | 1999-06-18 | 2001-03-06 | Nippon Sheet Glass Co Ltd | 透明積層体およびこれを用いたガラス物品 |
AR044724A1 (es) | 2000-03-27 | 2005-10-05 | Syngenta Participations Ag | Promotores del virus de la rizadura amarilla del cestrum |
US6607745B2 (en) | 2001-05-18 | 2003-08-19 | Harry Leneau | Ingestion of hyaluronic acid for improved joint function and health |
JP4702819B2 (ja) | 2001-08-01 | 2011-06-15 | 生化学工業株式会社 | コンドロイチン合成酵素 |
JP4101548B2 (ja) | 2001-08-10 | 2008-06-18 | 生化学工業株式会社 | コンドロイチン合成酵素及びそれをコードするdna |
KR100879908B1 (ko) | 2001-12-21 | 2009-01-21 | 노보자임스 바이오폴리머 에이/에스 | 재조합체 숙주 세포에서 히알루로난의 제조 방법 |
US20040003432A1 (en) * | 2002-05-06 | 2004-01-01 | Pharmacia Corporation | Production of hexosamines and uses thereof |
AU2003241687A1 (en) | 2002-05-31 | 2003-12-19 | Amersham Biosciences K.K. | Chondroitin synthetase and dna coding for the enzyme |
CN1833026A (zh) | 2003-07-31 | 2006-09-13 | 东洋纺织株式会社 | 生产透明质酸的植物 |
EP1640457A1 (de) * | 2004-09-23 | 2006-03-29 | Bayer CropScience GmbH | Verfahren und Mittel zur Herstellung von Hyaluronan |
AU2005287478B2 (en) * | 2004-09-23 | 2011-05-19 | Bayer Intellectual Property Gmbh | Methods and means for producing hyaluronan |
US8003851B2 (en) | 2005-08-25 | 2011-08-23 | Toyo Boseki Kabushiki Kaisha | Plant producing hyaluronic acid |
WO2007039316A1 (en) * | 2005-10-05 | 2007-04-12 | Bayer Cropscience Ag | Improved methods and means for producings hyaluronan |
CA2624338C (en) * | 2005-10-05 | 2016-09-13 | Bayer Cropscience Ag | Plants having an increased content of amino sugars |
AU2006298962A1 (en) | 2005-10-05 | 2007-04-12 | Bayer Cropscience Ag | Plants with an increased production of hyaluronan II |
JP2009509555A (ja) * | 2005-10-05 | 2009-03-12 | バイエル・クロップサイエンス・アーゲー | ヒアルロン酸の産生が増大した植物ii |
-
2007
- 2007-09-12 EP EP07116174A patent/EP2036983A1/de not_active Withdrawn
-
2008
- 2008-09-11 AU AU2008297527A patent/AU2008297527B2/en not_active Ceased
- 2008-09-11 JP JP2010524414A patent/JP5529741B2/ja not_active Expired - Fee Related
- 2008-09-11 CN CN200880115486.6A patent/CN101855354B/zh not_active Expired - Fee Related
- 2008-09-11 CA CA2698989A patent/CA2698989C/en not_active Expired - Fee Related
- 2008-09-11 WO PCT/EP2008/007837 patent/WO2009033752A1/en active Application Filing
- 2008-09-11 US US12/733,613 patent/US9150873B2/en not_active Expired - Fee Related
- 2008-09-11 EP EP08802357A patent/EP2190998B1/en not_active Not-in-force
- 2008-09-11 AT AT08802357T patent/ATE551425T1/de active
- 2008-09-12 AR ARP080103967A patent/AR068623A1/es unknown
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