JP2010537669A5 - - Google Patents
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- Publication number
- JP2010537669A5 JP2010537669A5 JP2010524099A JP2010524099A JP2010537669A5 JP 2010537669 A5 JP2010537669 A5 JP 2010537669A5 JP 2010524099 A JP2010524099 A JP 2010524099A JP 2010524099 A JP2010524099 A JP 2010524099A JP 2010537669 A5 JP2010537669 A5 JP 2010537669A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- reporter
- protease
- activating
- interaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96975607P | 2007-09-04 | 2007-09-04 | |
| US60/969,756 | 2007-09-04 | ||
| US8498708P | 2008-07-30 | 2008-07-30 | |
| US61/084,987 | 2008-07-30 | ||
| PCT/US2008/074543 WO2009032716A1 (en) | 2007-09-04 | 2008-08-28 | Identifying molecules that modulate protein- protein interactions using protease activated reporters |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010537669A JP2010537669A (ja) | 2010-12-09 |
| JP2010537669A5 true JP2010537669A5 (https=) | 2011-09-29 |
| JP5618829B2 JP5618829B2 (ja) | 2014-11-05 |
Family
ID=40029329
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010524099A Expired - Fee Related JP5618829B2 (ja) | 2007-09-04 | 2008-08-28 | プロテアーゼ活性化レポーターを使用してのタンパク質−タンパク質相互作用を調節する分子の同定 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US8574865B2 (https=) |
| EP (1) | EP2191275B1 (https=) |
| JP (1) | JP5618829B2 (https=) |
| KR (1) | KR101636306B1 (https=) |
| CN (1) | CN102187225B (https=) |
| AU (1) | AU2008296501B2 (https=) |
| BR (1) | BRPI0816289B1 (https=) |
| CA (1) | CA2698362C (https=) |
| CL (1) | CL2008002602A1 (https=) |
| CY (1) | CY1113816T1 (https=) |
| DK (1) | DK2191275T3 (https=) |
| ES (1) | ES2393642T3 (https=) |
| IL (1) | IL204260A (https=) |
| MX (1) | MX2010002399A (https=) |
| MY (1) | MY155343A (https=) |
| PL (1) | PL2191275T3 (https=) |
| PT (1) | PT2191275E (https=) |
| RU (1) | RU2476891C2 (https=) |
| TW (1) | TWI425094B (https=) |
| UY (1) | UY31323A1 (https=) |
| WO (1) | WO2009032716A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009032716A1 (en) * | 2007-09-04 | 2009-03-12 | Sanofi-Aventis | Identifying molecules that modulate protein- protein interactions using protease activated reporters |
| WO2014196932A1 (en) * | 2013-06-06 | 2014-12-11 | Agency For Science, Technology And Research | Protease-responsive peptide biosensors and methods for analyte detection |
| CA2930001A1 (en) | 2013-11-11 | 2015-05-14 | University Hospitals Cleveland Medical Center | Targeted treatment of anerobic cancer |
| CN107003323B (zh) | 2014-11-25 | 2019-06-04 | 文塔纳医疗系统公司 | 使用化学连接和半抗原转移的邻近测定法 |
| WO2016153880A2 (en) * | 2015-03-23 | 2016-09-29 | The Regents Of The University Of California | Methods for detection of rnase activity |
| RU2639539C2 (ru) * | 2015-12-29 | 2017-12-21 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Репортерная система на основе лентивирусных репортерных конструкций для изучения белок-белковых взаимодействий |
| US20180301048A1 (en) * | 2017-04-12 | 2018-10-18 | Age Of Learning, Inc. | Remote live tutoring platform |
| WO2020028381A1 (en) * | 2018-07-30 | 2020-02-06 | Montana Molecular, Llc | Biosensors for detecting arrestin signaling |
| JP2022513606A (ja) * | 2018-12-10 | 2022-02-09 | イエール ユニバーシティ | 宿主の生理機能を形成する微生物叢代謝産物 |
| JP2022551820A (ja) * | 2019-10-15 | 2022-12-14 | エフ．ホフマン－ラ ロシュ アーゲー | 細胞内または小胞内生体分子相互作用を検出するための人工膜貫通タンパク質 |
| WO2022259904A1 (ja) * | 2021-06-07 | 2022-12-15 | 国立研究開発法人理化学研究所 | プロテアーゼ活性測定用の融合タンパク質基質 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6528271B1 (en) | 1997-06-05 | 2003-03-04 | Duke University | Inhibition of βarrestin mediated effects prolongs and potentiates opioid receptor-mediated analgesia |
| US5891646A (en) | 1997-06-05 | 1999-04-06 | Duke University | Methods of assaying receptor activity and constructs useful in such methods |
| US7128915B2 (en) | 1997-09-18 | 2006-10-31 | Research Development Foundation | Membrane virus host range mutations and their uses as vaccine substrates |
| US6884870B2 (en) | 1998-03-20 | 2005-04-26 | California Institute Of Technology | Fusion proteins for identifying proteases, protease target sites and regulators of protease activity in living cells |
| US20030157553A1 (en) | 2000-03-03 | 2003-08-21 | Gabriel Berstein | Methods of assaying for G protein-coupled receptor ligands and modulators |
| EP1205191A1 (en) | 2000-11-13 | 2002-05-15 | Centre National De La Recherche Scientifique | Targeted modification of intracellular compounds |
| EP1353182A3 (en) | 2002-04-12 | 2004-02-04 | Smithkline Beecham Corporation | Method of predicting cell-based assay results using binding profiles |
| US20070224615A1 (en) * | 2003-07-09 | 2007-09-27 | Invitrogen Corporation | Methods for assaying protein-protein interactions |
| JP4734498B2 (ja) * | 2003-07-09 | 2011-07-27 | ライフ テクノロジーズ コーポレイション | タンパク質−タンパク質相互作用を解析する方法 |
| US7524925B2 (en) | 2004-11-18 | 2009-04-28 | Washington State University | Protein interaction reporter agents and methods for using same |
| WO2009032716A1 (en) * | 2007-09-04 | 2009-03-12 | Sanofi-Aventis | Identifying molecules that modulate protein- protein interactions using protease activated reporters |
| EP3508570B1 (en) * | 2010-05-11 | 2020-07-22 | Promega Corporation | Mutant protease biosensors with enhanced detection characteristics |
-
2008
- 2008-08-28 WO PCT/US2008/074543 patent/WO2009032716A1/en not_active Ceased
- 2008-08-28 CA CA 2698362 patent/CA2698362C/en not_active Expired - Fee Related
- 2008-08-28 BR BRPI0816289A patent/BRPI0816289B1/pt not_active IP Right Cessation
- 2008-08-28 JP JP2010524099A patent/JP5618829B2/ja not_active Expired - Fee Related
- 2008-08-28 PT PT08829659T patent/PT2191275E/pt unknown
- 2008-08-28 EP EP20080829659 patent/EP2191275B1/en active Active
- 2008-08-28 CN CN200880110461.7A patent/CN102187225B/zh active Active
- 2008-08-28 ES ES08829659T patent/ES2393642T3/es active Active
- 2008-08-28 AU AU2008296501A patent/AU2008296501B2/en active Active
- 2008-08-28 DK DK08829659T patent/DK2191275T3/da active
- 2008-08-28 RU RU2010112854/15A patent/RU2476891C2/ru not_active IP Right Cessation
- 2008-08-28 MX MX2010002399A patent/MX2010002399A/es active IP Right Grant
- 2008-08-28 MY MYPI2010000555A patent/MY155343A/en unknown
- 2008-08-28 US US12/676,284 patent/US8574865B2/en active Active
- 2008-08-28 KR KR1020107004803A patent/KR101636306B1/ko not_active Expired - Fee Related
- 2008-08-28 PL PL08829659T patent/PL2191275T3/pl unknown
- 2008-09-02 CL CL2008002602A patent/CL2008002602A1/es unknown
- 2008-09-04 TW TW97133835A patent/TWI425094B/zh not_active IP Right Cessation
- 2008-09-04 UY UY31323A patent/UY31323A1/es not_active Application Discontinuation
-
2010
- 2010-03-02 IL IL204260A patent/IL204260A/en not_active IP Right Cessation
-
2012
- 2012-11-08 CY CY20121101062T patent/CY1113816T1/el unknown
-
2013
- 2013-10-02 US US14/044,250 patent/US9023610B2/en active Active
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