JP2010535811A5 - - Google Patents
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- JP2010535811A5 JP2010535811A5 JP2010520313A JP2010520313A JP2010535811A5 JP 2010535811 A5 JP2010535811 A5 JP 2010535811A5 JP 2010520313 A JP2010520313 A JP 2010520313A JP 2010520313 A JP2010520313 A JP 2010520313A JP 2010535811 A5 JP2010535811 A5 JP 2010535811A5
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- conjugate
- cancer
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| US95440907P | 2007-08-07 | 2007-08-07 | |
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| EP1877428B1 (en) * | 2005-04-22 | 2011-03-16 | University of Washington | Cyanine- chlorotoxin conjugate and method for intra-operative visualization of cancer |
| BRPI0912683A2 (pt) | 2008-05-15 | 2016-01-26 | Transmolecular Inc | tratamento de tumores metastáticos |
| CN106995493B (zh) | 2010-02-04 | 2021-09-24 | 卫材公司 | 氯毒素多肽和结合物及其应用 |
| JP5909611B2 (ja) * | 2010-04-06 | 2016-04-27 | 愛知県 | 癌細胞選択的膜透過性ペプチドおよびその利用 |
| ES2601182T3 (es) | 2010-05-11 | 2017-02-14 | Fred Hutchinson Cancer Research Center | Variantes de clorotoxina, conjugados y métodos para su utilización |
| WO2013003507A1 (en) | 2011-06-27 | 2013-01-03 | Morphotek, Inc. | Multifunctional agents |
| US10156559B2 (en) | 2012-12-10 | 2018-12-18 | Fred Hutchinson Cancer Research Center | Lipocalin fusion partners |
| US11559580B1 (en) | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
| US12048732B2 (en) | 2016-04-15 | 2024-07-30 | Blaze Bioscience, Inc. | Methods of treating breast cancer |
| CN110352197B (zh) * | 2016-12-09 | 2024-02-02 | Uab研究基金会 | 嵌合氯毒素受体 |
| US11826399B2 (en) | 2017-09-15 | 2023-11-28 | Eisai Inc. | Chlorotoxin agents and uses thereof |
| US11866466B2 (en) | 2017-12-19 | 2024-01-09 | Blaze Bioscience, Inc. | Tumor homing and cell penetrating peptide-immuno-oncology agent complexes and methods of use thereof |
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| US5905027A (en) * | 1995-12-27 | 1999-05-18 | Uab Research Foundation | Method of diagnosing and treating gliomas |
| US6667156B2 (en) * | 1995-12-27 | 2003-12-23 | Uab Research Foundation | Diagnosis and treatment of neuroectodermal tumors |
| US20060088899A1 (en) * | 2002-05-31 | 2006-04-27 | Alvarez Vernon L | Combination chemotherapy with chlorotoxin |
| EP2431385A3 (en) * | 2002-05-31 | 2012-07-04 | Morphotek, Inc. | Combination therapy with chlorotoxin |
| JP2008507280A (ja) * | 2004-07-21 | 2008-03-13 | アンブレツクス・インコーポレイテツド | 非天然コードアミノ酸を用いた生合成ポリペプチド |
| EP1877428B1 (en) * | 2005-04-22 | 2011-03-16 | University of Washington | Cyanine- chlorotoxin conjugate and method for intra-operative visualization of cancer |
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- 2008-08-07 WO PCT/US2008/072524 patent/WO2009021136A1/en not_active Ceased
- 2008-08-07 EP EP08797415A patent/EP2173385A1/en not_active Withdrawn
- 2008-08-07 AU AU2008285364A patent/AU2008285364A1/en not_active Abandoned
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