JP2023504286A5 - - Google Patents

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Publication number
JP2023504286A5
JP2023504286A5 JP2022534289A JP2022534289A JP2023504286A5 JP 2023504286 A5 JP2023504286 A5 JP 2023504286A5 JP 2022534289 A JP2022534289 A JP 2022534289A JP 2022534289 A JP2022534289 A JP 2022534289A JP 2023504286 A5 JP2023504286 A5 JP 2023504286A5
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JP
Japan
Prior art keywords
item
composition according
immunomodulator
dendrimer
items
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022534289A
Other languages
English (en)
Japanese (ja)
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JP2023504286A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/063332 external-priority patent/WO2021113651A2/en
Publication of JP2023504286A publication Critical patent/JP2023504286A/ja
Publication of JP2023504286A5 publication Critical patent/JP2023504286A5/ja
Pending legal-status Critical Current

Links

JP2022534289A 2019-12-04 2020-12-04 薬物送達のためのデンドリマー組成物および方法 Pending JP2023504286A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962943705P 2019-12-04 2019-12-04
US62/943,705 2019-12-04
US202063108186P 2020-10-30 2020-10-30
US63/108,186 2020-10-30
PCT/US2020/063332 WO2021113651A2 (en) 2019-12-04 2020-12-04 Dendrimer compositions and methods for drug delivery

Publications (2)

Publication Number Publication Date
JP2023504286A JP2023504286A (ja) 2023-02-02
JP2023504286A5 true JP2023504286A5 (enExample) 2023-12-13

Family

ID=74104190

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022534289A Pending JP2023504286A (ja) 2019-12-04 2020-12-04 薬物送達のためのデンドリマー組成物および方法

Country Status (9)

Country Link
US (3) US20230226199A1 (enExample)
EP (1) EP4069307A2 (enExample)
JP (1) JP2023504286A (enExample)
CN (1) CN115103689A (enExample)
AU (1) AU2020397063A1 (enExample)
CA (1) CA3163886A1 (enExample)
IL (1) IL293604A (enExample)
PH (1) PH12022551368A1 (enExample)
WO (1) WO2021113651A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7759322B2 (ja) 2019-12-04 2025-10-23 アシュバッタ セラピューティクス, インコーポレイテッド 眼に薬物送達するためのデンドリマー組成物および方法
PH12022552818A1 (en) 2020-04-24 2024-03-25 Ashvattha Therapeutics Inc Dendrimer compositions and methods for treatment of severe acute respiratory distress syndrome
EP4181913A4 (en) * 2020-07-17 2025-02-19 Ashvattha Therapeutics, Inc. DENDRIMER COMPOSITIONS AND METHODS OF DRUG DELIVERY TO A DISEASED KIDNEY
EP4237009A4 (en) * 2020-10-30 2025-09-24 Ashvattha Therapeutics Inc Radiolabeled ether dendrimer conjugates for PET imaging and radiotherapy
US20240139107A1 (en) * 2021-03-08 2024-05-02 Transdermal Biotechnology, Inc. Dendrimer-n-acetyl-l-cysteine conjugates for treatment or prevention of aging skin or other indications
WO2022261504A1 (en) * 2021-06-10 2022-12-15 Ashvattha Therapeutics, Inc. Dendrimer conjugates and methods of use thereof
EP4490158A4 (en) * 2022-03-10 2026-01-07 Curators Of The University Of Missouri The NEW PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITOR, COMPOSITIONS CONTAINING IT, METHODS OF MANUFACTURING IT AND METHODS OF TREATING A DISEASE
WO2023183367A1 (en) * 2022-03-22 2023-09-28 Board Of Regents Of The University Of Nebraska Metformin nanoformulations and methods of use thereof
CN114796492B (zh) * 2022-05-12 2023-01-13 大连理工大学 一种超声驱动纳米声敏疫苗及其制备和应用
CN116196292B (zh) * 2023-02-16 2024-08-16 东华大学 一种靶向肽修饰的聚酰胺-胺树状大分子复合纳米材料及其制备方法
WO2025183982A1 (en) * 2024-02-28 2025-09-04 Washington State University Psma-targeted dendrimer nanoplatform for cancer detection and therapy
WO2025226820A1 (en) * 2024-04-23 2025-10-30 Ashvattha Therapeutics, Inc. Csf1r inhibitor dendrimer conjugates and uses thereof
CN118108799B (zh) * 2024-04-29 2024-07-12 内蒙古工业大学 基于DMXAA的含Se多肽药物及其制备方法和应用
WO2025259215A1 (en) 2024-06-14 2025-12-18 EGE Kimya San. ve Tic. A.S. Use of dendrimer compounds as complexing ligands for metal activity enhancement
WO2025259214A1 (en) 2024-06-14 2025-12-18 EGE Kimya San. ve Tic. A.S. Use of dendrimer compounds as anti-skinning agents
CN118846078A (zh) * 2024-07-02 2024-10-29 中国人民解放军空军军医大学 Ndrg2基因联合分子靶向抑制剂在制备肾细胞癌治疗药物中的应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856807A (en) 1972-03-13 1974-12-24 Upjohn Co L-({60 s,5s)-{60 -amino-3-chloro-2-isoxazoline-5-acetic acid
US3878047A (en) 1973-02-02 1975-04-15 Upjohn Co Process for production of AT-125
US5087639A (en) 1988-11-02 1992-02-11 The Upjohn Company Preventing CNS toxicity of acivicin when used with four large neutral amino acids
WO2005099768A2 (en) * 2004-03-23 2005-10-27 Complex Biosystems Gmbh Polymeric prodrug with a self-immolative linker
EP2214646B1 (en) * 2007-10-05 2021-06-23 Wayne State University Dendrimers for sustained release of compounds
WO2010147831A1 (en) 2009-06-15 2010-12-23 Wayne State University Dendrimer based nanodevices for therapeutic and imaging purposes
CA2830052C (en) 2010-03-31 2018-10-09 Wayne State University Injectable dendrimer hydrogel nanoparticles
US9198973B2 (en) * 2013-06-17 2015-12-01 Fundacion Fraunhofer Chile Research PAMAM, spacer molecule and cafestol polymers
CA3035502A1 (en) * 2014-04-30 2015-11-05 Kannan Rangaramanujam Dendrimer compositions and their use in treatment of diseases of the eye
DK3145984T3 (da) * 2014-05-21 2022-04-11 Icd Therapeutics Gmbh Terapeutiske konjugater med sulfaterede dendrimerer til intracellulær målretning
CN114392360A (zh) * 2014-08-13 2022-04-26 约翰霍普金斯大学 树枝状聚合物组合物和在治疗神经与cns病症中的用途
WO2016025741A1 (en) 2014-08-13 2016-02-18 The Johns Hopkins University Selective dendrimer delivery to brain tumors
CN107205940A (zh) * 2014-12-15 2017-09-26 约翰霍普金斯大学 舒尼替尼制剂及其在治疗眼部疾病中的使用方法
KR101918346B1 (ko) * 2015-05-06 2018-11-13 경북대학교 산학협력단 난용성 활성물질의 수용성 덴드리머 복합체
JP7108306B2 (ja) * 2015-10-29 2022-07-28 ザ・ジョンズ・ホプキンス・ユニバーシティー デンドリマー組成物ならびに壊死性腸炎および他の胃腸障害の処置における使用
US20190142953A1 (en) * 2016-05-10 2019-05-16 Massachusetts Institute Of Technology Dendrimer-Drug Conjugates, Hydrogel Compositions, and Methods
TWI773730B (zh) * 2017-02-22 2022-08-11 瑞典商阿斯特捷利康公司 治療性樹枝狀聚合物
EP3691689A1 (en) * 2017-10-05 2020-08-12 Sony Corporation Programmable dendritic drugs
CA3082121C (en) * 2017-11-10 2023-01-24 The Johns Hopkins University Dendrimer delivery system and methods of use thereof
EP3898942A4 (en) * 2018-12-21 2022-10-19 Tiba Biotech LLC NANOPARTICLE COMPOSITIONS FOR EFFICIENT NUCLEIC ACID DELIVERY AND METHODS OF MAKING AND USE THEREOF
JP7759322B2 (ja) * 2019-12-04 2025-10-23 アシュバッタ セラピューティクス, インコーポレイテッド 眼に薬物送達するためのデンドリマー組成物および方法

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