JP2010535767A - 栄養投与単位 - Google Patents
栄養投与単位 Download PDFInfo
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- JP2010535767A JP2010535767A JP2010519969A JP2010519969A JP2010535767A JP 2010535767 A JP2010535767 A JP 2010535767A JP 2010519969 A JP2010519969 A JP 2010519969A JP 2010519969 A JP2010519969 A JP 2010519969A JP 2010535767 A JP2010535767 A JP 2010535767A
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Landscapes
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- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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Abstract
Description
本出願は、2007年8月3日付け出願の米国仮出願第60/953,934号及び2007年8月3日付け出願の米国の仮出願第60/953,944号の優先権を主張し、両者を参照することによってここに組込む。
Claims (17)
- 被験者に用いられる経口栄養サプリメント投与単位であって、
前記投与単位がビタミンB12を含んでおり、
前記投与単位が、所定期間にわたって被験者の胃から始まり小腸まで引き続きビタミンB12を持続放出して提供する持続放出性の投与単位である、経口栄養サプリメント投与単位。 - 摂取後12時間以上の期間、ビタミンB12を高い血漿中濃度で提供するように製剤されていることを特徴とする請求項1に記載の投与単位。
- 37℃の0.1N HCl 900ml中にビタミンB12の15%以上が1時間で溶解するよう製剤されていることを特徴とする請求項1に記載の投与単位。
- 更に1種以上の追加のビタミンB類及びビタミンCを含むことを特徴とする請求項1に記載の投与単位。
- 30mg〜750mgのビタミンCと、
25mg〜400mgのカルシウムと、
1mg〜40mgのビタミンB1と、
1mg〜40mgのビタミンB2と、
10mg〜300mgのビタミンB5と、
1mg〜40mgのビタミンB6と、
6mcg〜500mcgのビタミンB12と、
1mg〜100mgのバイオフラボノイド複合体と、
5mg〜300mgのケルセチン
を含むことを特徴とする請求項1に記載の投与単位。 - 37℃の0.1N HCl 900ml中にビタミンB類及びビタミンCの15%以上が1時間で溶解するよう製剤されていることを特徴とする請求項5に記載の投与単位。
- 錠剤又はカプレットの形状であることを特徴とする請求項1に記載の投与単位。
- 更に外側フィルム被覆を具えることを特徴とする請求項7に記載の投与単位。
- 被験者に用いられる経口栄養サプリメント投与単位であって、
前記投与単位が、
30mg〜750mgのビタミンCと、
25mg〜400mgのカルシウムと、
1mg〜40mgのビタミンB1と、
1mg〜40mgのビタミンB2と、
10mg〜300mgのビタミンB5と、
1mg〜40mgのビタミンB6と、
6mcg〜500mcgのビタミンB12と、
1mg〜100mgのバイオフラボノイド複合体と、
5mg〜300mgのケルセチンと、
を含む、錠剤又はカプレットであって、
前記投与単位が、摂取後12時間以上の期間、ビタミンB12を高い血漿中濃度で提供するのに十分な期間にわたって被験者の胃から始まり小腸まで引き続きビタミンB12を持続放出して提供する持続放出性の投与単位である、経口栄養サプリメント投与単位。 - 被験者にビタミンB12を送達する方法であって、
前記方法が被験者に持続放出性栄養サプリメント投与単位を経口投与する工程を含み、
前記投与単位が、ビタミンB12を含み、
前記投与単位が、胃から始まり上部腸器官系まで引き続きビタミンB12を放出するように製剤されている、ビタミンB12の送達方法。 - 前記投与単位が、摂取後12時間以上の期間、ビタミンB12を高い血漿中濃度で提供するように製剤されていることを特徴とする請求項10に記載の方法。
- 前記投与単位が、37℃の0.1N HCl 900ml中にビタミンB12の15%以上が1時間で溶解するよう製剤されていることを特徴とする請求項10に記載の方法。
- 前記投与単位が、更に1種以上の追加のビタミンB類及びビタミンCを含むことを特徴とする請求項10に記載の方法。
- 前記投与単位が、37℃の0.1N HCl 900ml中にビタミンB類及びビタミンCの15%以上が1時間で溶解するよう製剤されていることを特徴とする請求項13に記載の方法。
- 前記投与単位が錠剤又はカプレットの形状であることを特徴とする請求項14に記載の方法。
- 前記投与単位が外側フィルム被覆を有することを特徴とする請求項15に記載の方法。
- 被験者にビタミンB12を送達する方法であって、
該方法が持続放出性栄養サプリメント投与単位を被験者に経口投与する工程を含み、
前記投与単位が、
30mg〜750mgのビタミンCと、
25mg〜400mgのカルシウムと、
1mg〜40mgのビタミンB1と、
1mg〜40mgのビタミンB2と、
10mg〜300mgのビタミンB5と、
1mg〜40mgのビタミンB6と、
6mcg〜500mcgのビタミンB12と、
1mg〜100mgのバイオフラボノイド複合体と、
5mg〜300mgのケルセチンと、
を含む、錠剤又はカプレットであって、
前記投与単位が、摂取後12時間以上の期間、胃から始まり上部腸器官系まで引き続き、ビタミンB12を高い血漿中濃度で提供するのに十分にビタミンB12を放出するように製剤されている、ビタミンB12の送達方法。
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JP (1) | JP2010535767A (ja) |
CN (1) | CN101815509A (ja) |
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US20100143533A1 (en) | 2010-06-10 |
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MX2010001260A (es) | 2010-04-07 |
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