JP2010535767A5 - - Google Patents
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- JP2010535767A5 JP2010535767A5 JP2010519969A JP2010519969A JP2010535767A5 JP 2010535767 A5 JP2010535767 A5 JP 2010535767A5 JP 2010519969 A JP2010519969 A JP 2010519969A JP 2010519969 A JP2010519969 A JP 2010519969A JP 2010535767 A5 JP2010535767 A5 JP 2010535767A5
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- JP
- Japan
- Prior art keywords
- dosage unit
- vitamin
- formulated
- subject
- hcl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- RMRCNWBMXRMIRW-WYVZQNDMSA-L Vitamin B12 Chemical compound N([C@@H]([C@@]1(C)[C@@](C)(CC(N)=O)[C@H](CCC(N)=O)\C(N1[Co+]C#N)=C(/C)\C1=N\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NCC(C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO RMRCNWBMXRMIRW-WYVZQNDMSA-L 0.000 claims 10
- VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 3
- 229930003268 Vitamin C Natural products 0.000 claims 3
- 235000015872 dietary supplement Nutrition 0.000 claims 3
- 229910000041 hydrogen chloride Inorganic materials 0.000 claims 3
- 230000002459 sustained Effects 0.000 claims 3
- 235000019154 vitamin C Nutrition 0.000 claims 3
- 239000011718 vitamin C Substances 0.000 claims 3
- 150000003700 vitamin C derivatives Chemical class 0.000 claims 3
- 210000002784 Stomach Anatomy 0.000 claims 2
- 230000037406 food intake Effects 0.000 claims 2
- 230000036470 plasma concentration Effects 0.000 claims 2
- 235000019156 vitamin B Nutrition 0.000 claims 2
- 239000011720 vitamin B Substances 0.000 claims 2
- 229940088594 Vitamin Drugs 0.000 claims 1
- 230000000968 intestinal Effects 0.000 claims 1
- 210000004789 organ systems Anatomy 0.000 claims 1
- 210000000813 small intestine Anatomy 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
- 150000003722 vitamin derivatives Chemical class 0.000 claims 1
- 229930003231 vitamins Natural products 0.000 claims 1
Claims (9)
- 被験者に用いられる経口栄養サプリメント投与単位であって、
前記投与単位がビタミンB12を含んでおり、
前記投与単位が、所定期間にわたって被験者の胃から始まり小腸まで引き続きビタミンB12を持続放出して提供する持続放出性の投与単位である、経口栄養サプリメント投与単位。 - 摂取後12時間以上の期間、ビタミンB12を高い血漿中濃度で提供するように製剤されていることを特徴とする請求項1に記載の投与単位。
- 37℃の0.1N HCl 900ml中にビタミンB12の15%以上が1時間で溶解するよう製剤されていることを特徴とする請求項1に記載の投与単位。
- 更に1種以上の追加のビタミンB類及びビタミンCを含むことを特徴とする請求項1に記載の投与単位。
- 被験者にビタミンB12を送達する方法であって、
前記方法が被験者に持続放出性栄養サプリメント投与単位を経口投与する工程を含み、
前記投与単位が、ビタミンB12を含み、
前記投与単位が、胃から始まり上部腸器官系まで引き続きビタミンB12を放出するように製剤されている、ビタミンB12の送達方法。 - 前記投与単位が、摂取後12時間以上の期間、ビタミンB12を高い血漿中濃度で提供するように製剤されていることを特徴とする請求項5に記載の方法。
- 前記投与単位が、37℃の0.1N HCl 900ml中にビタミンB12の15%以上が1時間で溶解するよう製剤されていることを特徴とする請求項5に記載の方法。
- 前記投与単位が、更に1種以上の追加のビタミンB類及びビタミンCを含むことを特徴とする請求項5に記載の方法。
- 前記投与単位が、37℃の0.1N HCl 900ml中にビタミンB類及びビタミンCの15%以上が1時間で溶解するよう製剤されていることを特徴とする請求項8に記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95394407P | 2007-08-03 | 2007-08-03 | |
US95393407P | 2007-08-03 | 2007-08-03 | |
PCT/US2008/009402 WO2009035496A1 (en) | 2007-08-03 | 2008-08-04 | Nutritional dosage unit |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010535767A JP2010535767A (ja) | 2010-11-25 |
JP2010535767A5 true JP2010535767A5 (ja) | 2011-09-22 |
Family
ID=40341943
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010519969A Pending JP2010535767A (ja) | 2007-08-03 | 2008-08-04 | 栄養投与単位 |
Country Status (7)
Country | Link |
---|---|
US (2) | US20100143533A1 (ja) |
JP (1) | JP2010535767A (ja) |
CN (1) | CN101815509A (ja) |
CA (1) | CA2695366C (ja) |
MX (1) | MX2010001260A (ja) |
TW (1) | TW200908892A (ja) |
WO (2) | WO2009020595A2 (ja) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010096564A2 (en) * | 2009-02-19 | 2010-08-26 | Probiohealth Llc | Dietary supplements containing polyunsaturated omega-3 fatty acids and probiotic bacteria with potential gastrointestinal and dermatological benefits |
US8853269B2 (en) * | 2010-02-04 | 2014-10-07 | Copperhead Chemical Company Inc. | Composition and method for treating infections and promoting intestinal health |
WO2011099031A1 (en) * | 2010-02-11 | 2011-08-18 | Zota Health Care Limited | Active antioxidants for all age group |
JP2012183063A (ja) * | 2011-02-14 | 2012-09-27 | Suntory Holdings Ltd | ケルセチン配糖体配合容器詰め飲料 |
US8183227B1 (en) | 2011-07-07 | 2012-05-22 | Chemo S. A. France | Compositions, kits and methods for nutrition supplementation |
US8168611B1 (en) | 2011-09-29 | 2012-05-01 | Chemo S.A. France | Compositions, kits and methods for nutrition supplementation |
US20170028183A1 (en) * | 2014-04-08 | 2017-02-02 | Mayo Foundation For Medical Education And Research | Ingestible capsule |
EP2962578A1 (en) * | 2014-06-30 | 2016-01-06 | Richard Hubertus Verheesen | Method of providing a plurality of nutrition portions to a user and packaging product |
US10799541B2 (en) * | 2014-07-01 | 2020-10-13 | Probi USA, Inc. | Bi-layer dual release probiotic tablets |
US20160073666A1 (en) * | 2014-09-16 | 2016-03-17 | New Chapter, Inc. | Supplement for a Breastfeeding Woman |
CA2969860A1 (en) * | 2015-01-07 | 2016-07-14 | Corr-Jensen Inc. | Compositions and methods for enhancing athletic performance |
CA2998863A1 (en) * | 2015-09-16 | 2017-03-23 | Corr-Jensen, Inc. | Multi-phase release of sports nutrition and energy drink compositions utilizing lipid particulates |
WO2017083549A1 (en) * | 2015-11-10 | 2017-05-18 | Probiotech Llc | Probiotic delivery systems |
US11291683B2 (en) * | 2016-04-01 | 2022-04-05 | Access Business Group International Llc | Bilayer tablets of B vitamins and process for preparing the same |
WO2018106921A1 (en) * | 2016-12-09 | 2018-06-14 | Balchem Corporation | Essential nutrients and related methods |
CN108836948B (zh) * | 2018-06-11 | 2024-04-12 | 宁波西敦医药包衣科技有限公司 | 一种利用包衣技术实现营养素可控制释放的产品 |
US20190388344A1 (en) | 2018-06-22 | 2019-12-26 | Probiotech Llc | Method to Improve The Health Of The Microbiome In A Human Gastrointestinal System and Multi-Chamber Probiotic Delivery Products Therefor |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3870790A (en) * | 1970-01-22 | 1975-03-11 | Forest Laboratories | Solid pharmaceutical formulations containing hydroxypropyl methyl cellulose |
US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
EP0208362A1 (en) * | 1985-06-28 | 1987-01-14 | The Procter & Gamble Company | Dietary supplements containing iron and enterically coated calcium |
NZ217821A (en) * | 1985-10-10 | 1989-07-27 | Biotech Australia Pty Ltd | Oral delivery system; complex of active agent and vitamin b12 or analogue thereof |
JP2643222B2 (ja) * | 1988-02-03 | 1997-08-20 | エーザイ株式会社 | 多重層顆粒 |
US5445826A (en) * | 1988-06-28 | 1995-08-29 | Cibus Pharmaceutical, Inc. | Delivery system containing a gel-forming dietary fiber and a drug |
CH680263A5 (ja) | 1989-07-20 | 1992-07-31 | Norman Godin | |
DE69124223T2 (de) * | 1990-02-05 | 1997-04-30 | Lifescience Corp | Vitamine und mineralien enthaltende nahrungszusätze |
US6451341B1 (en) * | 1990-02-05 | 2002-09-17 | Thomas J. Slaga | Time release formulation of vitamins, minerals and other beneficial supplements |
WO1994006415A1 (en) * | 1992-09-23 | 1994-03-31 | Kv Pharmaceutical Corporation | Multi-vitamin and mineral supplement for pregnant women |
US5723446A (en) * | 1993-12-23 | 1998-03-03 | Nestec Ltd. | Enteral formulation designed for optimized nutrient absorption and wound healing |
CA2199005A1 (en) * | 1994-09-01 | 1996-03-07 | Emile Bourland (Deceased) | Compositions and methods for delivery of polypeptides |
WO2000007463A1 (en) * | 1998-08-04 | 2000-02-17 | Kv Pharmaceutical Company | Multi-vitamin and mineral supplements for women |
US6428809B1 (en) * | 1999-08-18 | 2002-08-06 | Microdose Technologies, Inc. | Metering and packaging of controlled release medication |
US6805880B1 (en) * | 1999-08-20 | 2004-10-19 | Ferrosan A/S | Pharmaceutical delivery system for vitamin C and vitamin E and use of a combination of vitamin C and E for preventing or treating conditions involving oxidative stress |
GB0007419D0 (en) * | 2000-03-27 | 2000-05-17 | Smithkline Beecham Gmbh | Composition |
WO2002085415A1 (en) * | 2001-04-17 | 2002-10-31 | Biomatrix, Inc | Non-digestible sugar-coated products and process |
US6814983B2 (en) * | 2002-12-10 | 2004-11-09 | Everett Laboratories, Inc. | Compositions and methods for nutrition supplementation |
GB0403247D0 (en) * | 2004-02-13 | 2004-03-17 | Tillotts Pharma Ag | A pharmaceutical composition |
ITMI20042189A1 (it) * | 2004-11-16 | 2005-02-16 | Anidral Srl | Composizione a base di batteri probiotici e suo uso nella prevenzione e-o nel trattamento di patologie e-o infezioni respiratorie e nel miglioramento della funzionalita' intestinale |
US20060251722A1 (en) * | 2005-05-03 | 2006-11-09 | Novavax, Inc. | Multi-component vitamin and mineral supplement for the optimal absorption of components |
US20060270625A1 (en) * | 2005-05-13 | 2006-11-30 | Eastern Virginia Medical School | Nutraceuticals for the treatment of neuropathy |
-
2008
- 2008-08-04 MX MX2010001260A patent/MX2010001260A/es unknown
- 2008-08-04 CN CN200880101810A patent/CN101815509A/zh active Pending
- 2008-08-04 WO PCT/US2008/009399 patent/WO2009020595A2/en active Application Filing
- 2008-08-04 JP JP2010519969A patent/JP2010535767A/ja active Pending
- 2008-08-04 TW TW097129487A patent/TW200908892A/zh unknown
- 2008-08-04 CA CA2695366A patent/CA2695366C/en active Active
- 2008-08-04 WO PCT/US2008/009402 patent/WO2009035496A1/en active Application Filing
-
2010
- 2010-02-03 US US12/699,798 patent/US20100143533A1/en not_active Abandoned
-
2014
- 2014-02-28 US US14/194,528 patent/US9248095B2/en active Active
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