JP2010535015A5 - - Google Patents
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- Publication number
- JP2010535015A5 JP2010535015A5 JP2010517242A JP2010517242A JP2010535015A5 JP 2010535015 A5 JP2010535015 A5 JP 2010535015A5 JP 2010517242 A JP2010517242 A JP 2010517242A JP 2010517242 A JP2010517242 A JP 2010517242A JP 2010535015 A5 JP2010535015 A5 JP 2010535015A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- seq
- monoclonal antibody
- produced
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 34
- 108090000765 processed proteins & peptides Proteins 0.000 claims 22
- 210000004408 hybridoma Anatomy 0.000 claims 19
- 229920001184 polypeptide Polymers 0.000 claims 19
- 102000004196 processed proteins & peptides Human genes 0.000 claims 19
- 241000699666 Mus <mouse, genus> Species 0.000 claims 18
- 102000039446 nucleic acids Human genes 0.000 claims 17
- 108020004707 nucleic acids Proteins 0.000 claims 17
- 150000007523 nucleic acids Chemical class 0.000 claims 17
- 239000000523 sample Substances 0.000 claims 11
- 239000012472 biological sample Substances 0.000 claims 10
- 238000000034 method Methods 0.000 claims 8
- 108090000623 proteins and genes Proteins 0.000 claims 8
- 102000004169 proteins and genes Human genes 0.000 claims 8
- 241000194017 Streptococcus Species 0.000 claims 6
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 5
- 241000894006 Bacteria Species 0.000 claims 5
- 208000035109 Pneumococcal Infections Diseases 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 239000012634 fragment Substances 0.000 claims 4
- 230000002163 immunogen Effects 0.000 claims 4
- 230000000295 complement effect Effects 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 239000008280 blood Substances 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 238000003259 recombinant expression Methods 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 201000009906 Meningitis Diseases 0.000 claims 1
- 241000699670 Mus sp. Species 0.000 claims 1
- 206010033078 Otitis media Diseases 0.000 claims 1
- 206010035664 Pneumonia Diseases 0.000 claims 1
- 206010061372 Streptococcal infection Diseases 0.000 claims 1
- 108700029229 Transcriptional Regulatory Elements Proteins 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 230000000890 antigenic effect Effects 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 239000013068 control sample Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000002949 hemolytic effect Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 239000007922 nasal spray Substances 0.000 claims 1
- 229940097496 nasal spray Drugs 0.000 claims 1
- 239000006199 nebulizer Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96172307P | 2007-07-23 | 2007-07-23 | |
| PCT/CA2008/001353 WO2009012588A1 (en) | 2007-07-23 | 2008-07-23 | Immunogenic polypeptides and monoclonal antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013089148A Division JP6204053B2 (ja) | 2007-07-23 | 2013-04-22 | 免疫原性のポリペプチドおよびモノクローナル抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010535015A JP2010535015A (ja) | 2010-11-18 |
| JP2010535015A5 true JP2010535015A5 (cg-RX-API-DMAC7.html) | 2011-08-11 |
Family
ID=40280955
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010517242A Pending JP2010535015A (ja) | 2007-07-23 | 2008-07-23 | 免疫原性のポリペプチドおよびモノクローナル抗体 |
| JP2013089148A Expired - Fee Related JP6204053B2 (ja) | 2007-07-23 | 2013-04-22 | 免疫原性のポリペプチドおよびモノクローナル抗体 |
| JP2015196681A Pending JP2016005482A (ja) | 2007-07-23 | 2015-10-02 | 免疫原性のポリペプチドおよびモノクローナル抗体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013089148A Expired - Fee Related JP6204053B2 (ja) | 2007-07-23 | 2013-04-22 | 免疫原性のポリペプチドおよびモノクローナル抗体 |
| JP2015196681A Pending JP2016005482A (ja) | 2007-07-23 | 2015-10-02 | 免疫原性のポリペプチドおよびモノクローナル抗体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8337846B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2183366B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP2010535015A (cg-RX-API-DMAC7.html) |
| KR (1) | KR101595234B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN101802198B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008280799B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0814127A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2694466A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2397488T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL203429A0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009012588A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201001260B (cg-RX-API-DMAC7.html) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7128918B1 (en) | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
| US20130183350A1 (en) | 2009-12-22 | 2013-07-18 | Kevin Harper | Immunogenic compositions |
| US9649372B2 (en) | 2009-12-22 | 2017-05-16 | Sanofi Pasteur Limited | Immunogenic compositions and related methods |
| GB201003920D0 (en) * | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Method of treatment |
| JP6046632B2 (ja) | 2010-12-03 | 2016-12-21 | サノフィ パストゥール リミテッドＳａｎｏｆｉ Ｐａｓｔｅｕｒ Ｌｉｍｉｔｅｄ | 肺炎球菌に対する免疫用組成物 |
| CA2834834A1 (en) | 2011-05-17 | 2012-11-22 | Glaxosmithkline Biologicals S.A. | Vaccine against streptococcus pneumoniae |
| EP2810078A4 (en) | 2012-02-01 | 2016-02-17 | Oklahoma Med Res Found | HUMAN STREPTOCOCCUS PNEUMONIAE ANTIBODIES AND APPLICATIONS THEREOF |
| GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
| CN105754952B (zh) * | 2016-02-16 | 2020-07-10 | 中国农业科学院兰州兽医研究所 | 抗羊痘病毒k3l蛋白c末端的单克隆抗体及其应用 |
| GB201610599D0 (en) | 2016-06-17 | 2016-08-03 | Glaxosmithkline Biologicals Sa | Immunogenic Composition |
| US12320753B2 (en) * | 2018-03-20 | 2025-06-03 | Sanofi Pasteur Limited | Methods for determining adjuvanted protein concentration and percent adsorption using intrinsic fluorescence |
| AU2022220611A1 (en) * | 2021-02-09 | 2023-08-24 | University Of Georgia Research Foundation, Inc. | Human monoclonal antibodies against pneumococcal antigens |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL81370A (en) * | 1986-02-07 | 1991-06-30 | Genetic Systems Corp | Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions |
| AU681573B2 (en) * | 1991-11-22 | 1997-09-04 | Glaxosmithkline Biologicals Sa | Type I and type II surface antigens associated with (staphylococcus epidermidis) |
| US6582708B1 (en) * | 2000-06-28 | 2003-06-24 | The Procter & Gamble Company | Tooth whitening substance |
| DE69940439D1 (de) | 1998-12-21 | 2009-04-02 | Medimmune Inc | Streptococcus pneumoniae proteine und immunogene fragmente für impstoffe |
| US7128918B1 (en) * | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
| NZ512574A (en) * | 1998-12-23 | 2004-03-26 | Iaf Biochem Int | Novel streptococcus antigens useful as vaccines |
| CN1198932C (zh) * | 1999-03-26 | 2005-04-27 | 科特克斯(Om)有限公司 | 肺炎链球菌抗原 |
| CA2410604A1 (en) * | 2000-06-14 | 2001-12-20 | Cytovax Biotechnologies, Inc. | Use of coiled-coil structural scaffold to generate structure-specific peptides |
| EP2281891A3 (en) | 2000-06-20 | 2011-08-17 | ID Biomedical Corporation | Streptococcus antigens |
| US7074415B2 (en) * | 2000-06-20 | 2006-07-11 | Id Biomedical Corporation | Streptococcus antigens |
| GB0022742D0 (en) * | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| GB0130215D0 (en) * | 2001-12-18 | 2002-02-06 | Glaxosmithkline Biolog Sa | Vaccine |
| AU2002351623A1 (en) * | 2001-12-20 | 2003-07-09 | Shire Biochem Inc. | Streptococcus antigens |
| US6720918B2 (en) * | 2002-09-17 | 2004-04-13 | Space Systems/Loral, Inc. | Antenna distortion estimation and compensation |
| EP2311987A1 (en) * | 2003-04-15 | 2011-04-20 | Intercell AG | S. pneumoniae antigens |
| US20060189791A1 (en) * | 2003-07-10 | 2006-08-24 | Wyeth Holdings Corporation | Recombinant expression of streptococcus pyogenes cysteine protease and immunogenic compositions thereof |
| JP5219803B2 (ja) * | 2005-05-13 | 2013-06-26 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド | グラム陽性菌の血清耐性因子 |
| JP5509176B2 (ja) * | 2011-10-21 | 2014-06-04 | 株式会社日立製作所 | 計算機システムおよび計算機システムにおけるモジュール引き継ぎ方法 |
-
2008
- 2008-07-23 CA CA2694466A patent/CA2694466A1/en not_active Abandoned
- 2008-07-23 AU AU2008280799A patent/AU2008280799B2/en not_active Ceased
- 2008-07-23 JP JP2010517242A patent/JP2010535015A/ja active Pending
- 2008-07-23 CN CN200880108203.5A patent/CN101802198B/zh not_active Expired - Fee Related
- 2008-07-23 WO PCT/CA2008/001353 patent/WO2009012588A1/en not_active Ceased
- 2008-07-23 US US12/670,150 patent/US8337846B2/en not_active Expired - Fee Related
- 2008-07-23 KR KR1020107003640A patent/KR101595234B1/ko not_active Expired - Fee Related
- 2008-07-23 ES ES08783266T patent/ES2397488T3/es active Active
- 2008-07-23 BR BRPI0814127-4A2A patent/BRPI0814127A2/pt not_active Application Discontinuation
- 2008-07-23 EP EP08783266A patent/EP2183366B1/en not_active Not-in-force
-
2010
- 2010-01-21 IL IL203429A patent/IL203429A0/en unknown
- 2010-02-22 ZA ZA201001260A patent/ZA201001260B/xx unknown
-
2013
- 2013-04-22 JP JP2013089148A patent/JP6204053B2/ja not_active Expired - Fee Related
-
2015
- 2015-10-02 JP JP2015196681A patent/JP2016005482A/ja active Pending
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