JP2010534697A - 悪液質予防補助食品 - Google Patents
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- 235000019149 tocopherols Nutrition 0.000 description 1
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- 239000011731 tocotrienol Substances 0.000 description 1
- 229940068778 tocotrienols Drugs 0.000 description 1
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- NGSWKAQJJWESNS-ZZXKWVIFSA-N trans-4-coumaric acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C=C1 NGSWKAQJJWESNS-ZZXKWVIFSA-N 0.000 description 1
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 230000014848 ubiquitin-dependent protein catabolic process Effects 0.000 description 1
- 208000009852 uremia Diseases 0.000 description 1
- 235000012141 vanillin Nutrition 0.000 description 1
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Animal Behavior & Ethology (AREA)
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- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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- Botany (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Child & Adolescent Psychology (AREA)
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
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- Oscillators With Electromechanical Resonators (AREA)
Abstract
Description
関連する兆候を伴う炎症促進性サイトカイン
代謝亢進
神経伝達物質
ホルモン変化
食欲不振
である。
Claims (16)
- 栄養組成物であって:
(a)総組成物100kcalを基準にしてエイコサペンタエン酸またはこれらの誘導体0.1から10g;および
(b)総組成物100kcalを基準にしてフィトケミカルまたはこれらの混合物0.1から10g
を含む組成物。 - (c)総組成物100kcalを基準にして、中性または塩の形態での、ロイシン(Leu)、イソロイシン(Ile)、およびバリン(Val)、からなる群から選択される1以上の分岐鎖アミン酸またはこれらの前駆体もしくは誘導体0.1から50g
をさらに含む、請求項1に記載の組成物。 - 分岐鎖アミノ酸が、Leu:Ile:Valの比が25%から75%:15%から35%:15%から35%で含まれる、請求項2に記載の組成物。
- (d)総組成物100kcalを基準にして中性または塩の形態のグルタミンまたはこれらの前駆体もしくは誘導体0.25から50g
をさらに含む、請求項1から3のいずれか一項に記載の組成物。 - (e)混合カロテノイド、ビタミンE、ビタミンC、亜鉛、マグネシウム、およびセレンからなる群から選択される1以上の酸化防止剤
をさらに含む、請求項1から4のいずれか一項に記載の組成物。 - 総組成物100kcalを基準にして、混合カロテノイド0.25から10mg、好ましくは1から10mg;ビタミンE3から300mg、好ましくは10から150mg;ビタミンC10から500mg、好ましくは15から500mg;およびセレン3から300μg、好ましくは15から150μgを含む、請求項5に記載の組成物。
- フィトケミカルが、5,000から20,000μmol/g抽出物、好ましくは10,000から15,000μmol/g抽出物のORAC値を満たす、請求項1から6のいずれか一項に記載の組成物。
- フィトケミカルが、カモミール、オリーブ、赤ワイン、緑茶および/またはリンゴから誘導され、好ましくはこの天然源内で存在する状態で含有される、請求項1から7のいずれか一項に記載の組成物。
- (a)総組成物100kcalを基準にして、エイコサペンタエン酸またはこれらの誘導体0.1から10g;
(b)総組成物100kcalを基準にして、フィトケミカルまたはこれらの混合物0.1から10g;
(c)総組成物100kcalを基準にしてそれぞれ、中性または塩の形態での、ロイシン(Leu)0.25から10g、イソロイシン(Ile)0.1から5g、およびバリン(Val)0.1から5g、またはこれらの前駆体もしくは誘導体;
(d)総組成物100kcalを基準にして、中性または塩の形態のグルタミン、またはこれらの前駆体もしくは誘導体0.25から10g;および
(e)総組成物100kcalを基準にして、混合カロテノイド0.25から10mg、ビタミンE3から300mg、ビタミンC10から500mg、およびセレン3から300μg
を含む、請求項1から8のいずれか一項に記載の組成物。 - (a)1日の用量あたり、エイコサペンタエン酸またはこれらの誘導体0.2から20g;
(b)1日の用量あたり、フィトケミカルまたはこれらの混合物0.2から20g;
(c)場合により、1日の用量あたり、中性または塩の形態での、ロイシン(Leu)、イソロイシン(Ile)、およびバリン(Val)からなる群から選択される1以上の分岐鎖アミノ酸、またはこれらの前駆体もしくは誘導体0.2から100g;
(d)場合により、1日の用量あたり、中性または塩の形態のグルタミンまたはこれらの前駆体もしくは誘導体0.5から100g;および
(e)場合により、1日の用量あたり、混合カロテノイド10から40mg、ビタミンE40から600mg、ビタミンC200から2000mg、およびセレン50から750μg
を含む、栄養組成物。 - 薬剤として、好ましくは栄養補助食品として使用するための、請求項1から10のいずれか一項に記載の組成物。
- 悪液質および/または食欲不振の処置および/または予防のための薬剤の調製における、請求項1から10のいずれか一項に記載の組成物の使用。
- (a)エイコサペンタエン酸またはこれらの誘導体;
(b)少なくとも1つのフィトケミカル;
(c)場合により、中性または塩の形態での、ロイシン(Leu)、イソロイシン(Ile)、およびバリン(Val)からなる群から選択される1以上の分岐鎖アミン酸またはこれらの前駆体もしくは誘導体;
(d)場合により、中性または塩の形態のグルタミンまたはこれらの前駆体もしくは誘導体;および
(e)場合により、β−カロテン、ビタミンE、ビタミンC、およびセレン;
を含む栄養組成物の、悪液質および/または食欲不振の処置および/または予防用薬剤の調製における使用であって、投与されるべき用量が、エイコサペンタエン酸またはこれらの誘導体0.2から20g/日;フィトケミカル0.2から20g/日;および組成物に存在する場合、ロイシン6から50g/日;イソロイシン3から25g/日;バリン3から25g/日;グルタミン8から50g/日、混合カロテノイド10から40mg/日、ビタミンE40から600mg/日、ビタミンC200から2000mg/日、およびセレン50から750μg/日である、使用。 - 組成物によって患者に供給される1日あたりの総カロリー値が400kcal以下、好ましくは300kcal以下、より好ましくは200kcal以下である、請求項12および/または13のいずれか一項に記載の使用。
- 請求項1から10のいずれか一項に記載の組成物および医薬的に許容できる賦形剤を含む悪液質および/または食欲不振の処置および/または予防のための薬剤、好ましくは栄養補助食品。
- 200kcal以下、好ましくは150kcal以下のカロリー値を与える、請求項1から9のいずれか一項に記載の組成物を含むサッシェ。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07015027A EP2025248A1 (en) | 2007-07-31 | 2007-07-31 | Cachexia prevention supplement |
PCT/EP2008/006281 WO2009015879A1 (en) | 2007-07-31 | 2008-07-30 | Cachexia prevention supplement |
Publications (1)
Publication Number | Publication Date |
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JP2010534697A true JP2010534697A (ja) | 2010-11-11 |
Family
ID=39326729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010518561A Pending JP2010534697A (ja) | 2007-07-31 | 2008-07-30 | 悪液質予防補助食品 |
Country Status (8)
Country | Link |
---|---|
US (1) | US20100189816A1 (ja) |
EP (2) | EP2025248A1 (ja) |
JP (1) | JP2010534697A (ja) |
CN (1) | CN101801219A (ja) |
AT (1) | ATE538666T1 (ja) |
ES (1) | ES2380164T3 (ja) |
HK (1) | HK1143047A1 (ja) |
WO (1) | WO2009015879A1 (ja) |
Cited By (4)
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KR101393496B1 (ko) | 2014-02-25 | 2014-05-13 | 유원석 | 봉합사 삽입키트 |
WO2019172714A1 (ko) * | 2018-03-09 | 2019-09-12 | 주식회사 뉴트리사이언스 | 캐모마일 추출물을 포함하는 근기능 및 운동능 강화 기능성 식품 조성물 및 그 제조방법 |
JP2020503388A (ja) * | 2016-12-23 | 2020-01-30 | ビーエーエスエフ エーエス | 悪液質を予防及び/又は処置するためのオメガ−3脂肪酸組成物 |
WO2021132897A1 (ko) * | 2019-12-27 | 2021-07-01 | 경희대학교 산학협력단 | 피페린을 함유하는 암성 악액질 예방, 개선 또는 치료용 조성물 |
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NL1036746C2 (nl) * | 2009-03-20 | 2010-09-21 | Glnp Holding B.V. | Kit van onderdelen bevattende l-glutamine en egcg. |
EP2241198A1 (en) * | 2009-04-07 | 2010-10-20 | Fresenius Kabi Deutschland GmbH | Mucositis prevention supplement and treatment |
WO2010137944A1 (en) * | 2009-05-27 | 2010-12-02 | N.V. Nutricia | Treatment of hypercalcaemia |
IT1395408B1 (it) * | 2009-08-31 | 2012-09-14 | Cangiano | Formulazione farmaceutica a base di aminoacidi a catena ramificata per la cura della sindrome anoressia nausea e vomito (sanv) da chemioterapici |
JP5576097B2 (ja) * | 2009-11-17 | 2014-08-20 | 大塚製薬株式会社 | 気道抵抗改善剤 |
WO2012141316A1 (ja) * | 2011-04-13 | 2012-10-18 | 味の素株式会社 | 栄養組成物 |
WO2019109050A1 (en) | 2017-11-30 | 2019-06-06 | University Of South Florida | Prevention and treatment of muscle wasting with ketone supplementation |
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- 2008-07-30 JP JP2010518561A patent/JP2010534697A/ja active Pending
- 2008-07-30 EP EP08785226A patent/EP2170103B1/en not_active Revoked
- 2008-07-30 AT AT08785226T patent/ATE538666T1/de active
- 2008-07-30 US US12/452,897 patent/US20100189816A1/en not_active Abandoned
- 2008-07-30 ES ES08785226T patent/ES2380164T3/es active Active
- 2008-07-30 CN CN200880102203A patent/CN101801219A/zh active Pending
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2010
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KR101393496B1 (ko) | 2014-02-25 | 2014-05-13 | 유원석 | 봉합사 삽입키트 |
JP2020503388A (ja) * | 2016-12-23 | 2020-01-30 | ビーエーエスエフ エーエス | 悪液質を予防及び/又は処置するためのオメガ−3脂肪酸組成物 |
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WO2021132897A1 (ko) * | 2019-12-27 | 2021-07-01 | 경희대학교 산학협력단 | 피페린을 함유하는 암성 악액질 예방, 개선 또는 치료용 조성물 |
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HK1143047A1 (en) | 2010-12-24 |
WO2009015879A1 (en) | 2009-02-05 |
CN101801219A (zh) | 2010-08-11 |
US20100189816A1 (en) | 2010-07-29 |
ATE538666T1 (de) | 2012-01-15 |
EP2170103A1 (en) | 2010-04-07 |
EP2025248A1 (en) | 2009-02-18 |
EP2170103B1 (en) | 2011-12-28 |
ES2380164T3 (es) | 2012-05-09 |
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