JP2010533200A5 - - Google Patents

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Publication number
JP2010533200A5
JP2010533200A5 JP2010516239A JP2010516239A JP2010533200A5 JP 2010533200 A5 JP2010533200 A5 JP 2010533200A5 JP 2010516239 A JP2010516239 A JP 2010516239A JP 2010516239 A JP2010516239 A JP 2010516239A JP 2010533200 A5 JP2010533200 A5 JP 2010533200A5
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JP
Japan
Prior art keywords
cell
stim2
stim1
cells
protein
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JP2010516239A
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English (en)
Japanese (ja)
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JP5559049B2 (ja
JP2010533200A (ja
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Priority claimed from PCT/US2008/069636 external-priority patent/WO2009009655A1/en
Publication of JP2010533200A publication Critical patent/JP2010533200A/ja
Publication of JP2010533200A5 publication Critical patent/JP2010533200A5/ja
Application granted granted Critical
Publication of JP5559049B2 publication Critical patent/JP5559049B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010516239A 2007-07-10 2008-07-10 間質相互作用分子ノックアウトマウス及びその使用 Expired - Fee Related JP5559049B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95902307P 2007-07-10 2007-07-10
US60/959,023 2007-07-10
PCT/US2008/069636 WO2009009655A1 (en) 2007-07-10 2008-07-10 Stromal interacting molecule knockout mouse and uses thereof

Publications (3)

Publication Number Publication Date
JP2010533200A JP2010533200A (ja) 2010-10-21
JP2010533200A5 true JP2010533200A5 (enExample) 2011-08-11
JP5559049B2 JP5559049B2 (ja) 2014-07-23

Family

ID=40229055

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010516239A Expired - Fee Related JP5559049B2 (ja) 2007-07-10 2008-07-10 間質相互作用分子ノックアウトマウス及びその使用

Country Status (4)

Country Link
US (2) US20100323371A1 (enExample)
EP (2) EP2244700A4 (enExample)
JP (1) JP5559049B2 (enExample)
WO (1) WO2009009655A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1984400B1 (en) 2006-01-05 2012-11-28 Immune Disease Institute, Inc. Regulators of nfat
US20110023152A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genome editing of cognition related genes in animals
US20110023151A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genome editing of abc transporters
US20110023139A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genomic editing of genes involved in cardiovascular disease
US20110016540A1 (en) * 2008-12-04 2011-01-20 Sigma-Aldrich Co. Genome editing of genes associated with trinucleotide repeat expansion disorders in animals
US20110023147A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genomic editing of prion disorder-related genes in animals
US20110023158A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Bovine genome editing with zinc finger nucleases
US20110023153A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genomic editing of genes involved in alzheimer's disease
US20110023146A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genomic editing of genes involved in secretase-associated disorders
US20110023149A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genomic editing of genes involved in tumor suppression in animals
US20110023140A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Rabbit genome editing with zinc finger nucleases
US20110016541A1 (en) * 2008-12-04 2011-01-20 Sigma-Aldrich Co. Genome editing of sensory-related genes in animals
US20110030072A1 (en) * 2008-12-04 2011-02-03 Sigma-Aldrich Co. Genome editing of immunodeficiency genes in animals
US20110016543A1 (en) * 2008-12-04 2011-01-20 Sigma-Aldrich Co. Genomic editing of genes involved in inflammation
US20110023144A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genomic editing of genes involved in amyotrophyic lateral sclerosis disease
US20110023150A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genome editing of genes associated with schizophrenia in animals
US20110023145A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genomic editing of genes involved in autism spectrum disorders
US20110023143A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genomic editing of neurodevelopmental genes in animals
US20110016546A1 (en) * 2008-12-04 2011-01-20 Sigma-Aldrich Co. Porcine genome editing with zinc finger nucleases
US20110016539A1 (en) * 2008-12-04 2011-01-20 Sigma-Aldrich Co. Genome editing of neurotransmission-related genes in animals
US20110023141A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genomic editing of genes involved with parkinson's disease
US20110023154A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Silkworm genome editing with zinc finger nucleases
US20110023148A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Genome editing of addiction-related genes in animals
US20110023156A1 (en) * 2008-12-04 2011-01-27 Sigma-Aldrich Co. Feline genome editing with zinc finger nucleases
US20120189613A1 (en) * 2009-05-29 2012-07-26 Julius-Maximilians-Universität Würzburg Stim2-mediated capacitive calcium entry
WO2010148393A2 (en) * 2009-06-19 2010-12-23 Immune Disease Institute, Inc. Assay for orai calcium channel regulators
WO2012092379A2 (en) 2010-12-29 2012-07-05 Sigma-Aldrich Co. Llc Cells having disrupted expression of proteins involved in adme and toxicology processes
ES2654674T3 (es) * 2014-08-06 2018-02-14 Université De Bretagne Occidentale (U.B.O.) Método para seleccionar compuestos usando membrana de STIM1

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4950598A (en) 1982-09-22 1990-08-21 The Board Of Trustees Of The Leland Stanford Junior University Process for making T cell hybridomas
WO1996012025A1 (en) 1994-10-14 1996-04-25 Basf Aktiengesellschaft TRANSGENIC NONHUMAN ANIMAL HAVING FUNCTIONALLY DISRUPTED INTERLEUKIN-1β CONVERTING ENZYME GENE
US6103523A (en) 1996-04-29 2000-08-15 Thromb-X N.V. Pluripotent rabbit cell lines and method of making
US6060642A (en) 1997-08-15 2000-05-09 The Regents Of The University Of California Serotonin 5-HT6 receptor knockout mouse
EP0976823A1 (de) * 1998-07-22 2000-02-02 Helge Dr. Völkel Rekombinantes Expressions System und Hoch-Durchsatz BioAssay für die therapeutische Anwendung von Calcineurin-A-Alpha, Calcineurin-A-Beta, Calcineurin-A-Gamma, Calcineurin-B und Copper/Zinc-Superoxide Dismutase bzw. zur Identifizierung von Pharmazeutika
EP1144597A2 (en) 1999-01-21 2001-10-17 Vitro Diagnostics, Inc. Immortalized cell lines and methods of making the same
US6747187B1 (en) 1999-08-05 2004-06-08 Henry M. Jackson Foundation For The Advancement Of Military Medicine Knockout mouse for the tumor suppressor gene ANX7
US6365796B1 (en) 2000-02-16 2002-04-02 Beth Israel Deaconess Medical Center Transgenic UCP2 knockout mouse and use thereof
WO2002030976A1 (en) * 2000-10-11 2002-04-18 The University Of Melbourne Cell control nucleic acids and proteins
WO2002072768A2 (en) 2001-03-09 2002-09-19 Todd Waldman ISOGENIC ss-CATENIN CELL LINES, AND METHODS OF MAKING AND USING SAME
US7645588B2 (en) 2003-03-04 2010-01-12 Calcimedica, Inc. Composition comprising a cell comprising a STIM1 protein and an agent that modulates intracellular calcium and methods of use
JP4551108B2 (ja) 2004-04-02 2010-09-22 進 清野 Ｎｏｃ２ノックアウトマウス
US7481994B2 (en) * 2005-06-07 2009-01-27 The Board Of Trustees Of The Leland Stanford Junior University Calcium biosensor polypeptides and methods of use
CA2648588A1 (en) * 2006-04-10 2007-10-25 The Queen's Medical Center Crac modulators and use of same for drug discovery
WO2007139926A2 (en) * 2006-05-26 2007-12-06 The Regents Of The University Of California Crac channel and modulator screening methods

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