JP2010532764A5 - - Google Patents
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- JP2010532764A5 JP2010532764A5 JP2010515288A JP2010515288A JP2010532764A5 JP 2010532764 A5 JP2010532764 A5 JP 2010532764A5 JP 2010515288 A JP2010515288 A JP 2010515288A JP 2010515288 A JP2010515288 A JP 2010515288A JP 2010532764 A5 JP2010532764 A5 JP 2010532764A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- specific binding
- binding protein
- domain
- residues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000009870 specific binding Effects 0.000 claims 34
- 102000023732 binding proteins Human genes 0.000 claims 27
- 108091008324 binding proteins Proteins 0.000 claims 27
- 208000011380 COVID-19–associated multisystem inflammatory syndrome in children Diseases 0.000 claims 11
- 238000002319 photoionisation mass spectrometry Methods 0.000 claims 11
- 235000018102 proteins Nutrition 0.000 claims 5
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 208000023275 Autoimmune disease Diseases 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 2
- 230000003013 cytotoxicity Effects 0.000 claims 2
- 231100000135 cytotoxicity Toxicity 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000012636 effector Substances 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 102100025218 B-cell differentiation antigen CD72 Human genes 0.000 claims 1
- 102100024222 B-lymphocyte antigen CD19 Human genes 0.000 claims 1
- 102100022005 B-lymphocyte antigen CD20 Human genes 0.000 claims 1
- 102000017420 CD3 protein, epsilon/gamma/delta subunit Human genes 0.000 claims 1
- 108050005493 CD3 protein, epsilon/gamma/delta subunit Proteins 0.000 claims 1
- 101000934359 Homo sapiens B-cell differentiation antigen CD72 Proteins 0.000 claims 1
- 101000980825 Homo sapiens B-lymphocyte antigen CD19 Proteins 0.000 claims 1
- 101000897405 Homo sapiens B-lymphocyte antigen CD20 Proteins 0.000 claims 1
- 101000777628 Homo sapiens Leukocyte antigen CD37 Proteins 0.000 claims 1
- 101000914514 Homo sapiens T-cell-specific surface glycoprotein CD28 Proteins 0.000 claims 1
- 102100031586 Leukocyte antigen CD37 Human genes 0.000 claims 1
- 102100027213 T-cell-specific surface glycoprotein CD28 Human genes 0.000 claims 1
- 230000027455 binding Effects 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000002523 lectin Substances 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000001575 pathological effect Effects 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 102220288073 rs151218932 Human genes 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94839707P | 2007-07-06 | 2007-07-06 | |
| PCT/US2008/069378 WO2009023386A2 (en) | 2007-07-06 | 2008-07-07 | Binding peptides having a c-terminally disposed specific binding domain |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010532764A JP2010532764A (ja) | 2010-10-14 |
| JP2010532764A5 true JP2010532764A5 (show.php) | 2011-08-25 |
Family
ID=40351400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515288A Pending JP2010532764A (ja) | 2007-07-06 | 2008-07-07 | Ｃ末端に配置された特異的結合性ドメインを有する結合性ペプチド |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090148447A1 (show.php) |
| EP (1) | EP2167130A2 (show.php) |
| JP (1) | JP2010532764A (show.php) |
| CN (1) | CN101990439A (show.php) |
| AU (1) | AU2008287195A1 (show.php) |
| BR (1) | BRPI0814060A2 (show.php) |
| CA (1) | CA2691819A1 (show.php) |
| WO (1) | WO2009023386A2 (show.php) |
Families Citing this family (52)
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| ES2368700T3 (es) * | 2008-04-11 | 2011-11-21 | Emergent Product Development Seattle, Llc | Agente inmunoterapéutico para cd37 y combinación con un agente quimioterapéutico bifuncional del mismo. |
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| KR20250037576A (ko) * | 2011-04-29 | 2025-03-17 | 유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 | 치료적 뉴클레아제 조성물 및 방법 |
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| RS57397B8 (sr) | 2011-06-10 | 2020-01-31 | Univ Oregon Health & Science | Cmv glikoproteini i rekombinantni vektori |
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| JP2017504601A (ja) * | 2013-12-20 | 2017-02-09 | セレクティスＣｅｌｌｅｃｔｉｓ | 免疫療法のためにマルチインプットシグナル感受性ｔ細胞を操作する方法 |
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| UA129489C2 (uk) | 2015-08-28 | 2025-05-14 | Дебіофарм Інтернаціонал, С.А. | Антитіло до cd37 |
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| AU2016355468B2 (en) | 2015-11-20 | 2022-12-15 | Oregon Health & Science University | CMV vectors comprising microRNA recognition elements |
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| US11278629B2 (en) | 2016-11-02 | 2022-03-22 | Debiopharm International, S.A. | Methods for improving anti-CD37 immunoconjugate therapy |
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| CN108395482B (zh) | 2017-02-08 | 2021-02-05 | 西比曼生物科技（香港）有限公司 | 一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定 |
| AU2018236450A1 (en) | 2017-03-16 | 2019-10-03 | The General Hospital Corporation | Chimeric antigen receptors targeting CD37 |
| JP7374091B2 (ja) | 2017-08-22 | 2023-11-06 | サナバイオ， エルエルシー | 可溶性インターフェロン受容体およびその使用 |
| CN112218662A (zh) | 2018-05-30 | 2021-01-12 | 德彪发姆国际有限公司 | 抗cd37免疫缀合物给药方案 |
| EP3793578A4 (en) * | 2018-06-22 | 2022-03-23 | The General Hospital Corporation | Chimeric antigen receptors targeting cd37 and cd19 |
| US20220242962A1 (en) | 2019-08-12 | 2022-08-04 | Aptevo Research And Development Llc | 4-1bb and ox40 binding proteins and related compositions and methods, antibodies against 4-1bb, antibodies against ox40 |
| CN113402612A (zh) | 2020-03-17 | 2021-09-17 | 西比曼生物科技（香港）有限公司 | 靶向cd19和cd20的联合嵌合抗原受体及其应用 |
| WO2022104692A1 (en) * | 2020-11-20 | 2022-05-27 | Bliss Biopharmaceutical (Hangzhou) Co., Ltd. | Engineered antibody, antibody-drug conjugate, and use thereof |
| IL303328A (en) | 2020-12-01 | 2023-07-01 | Aptevo Res & Development Llc | Heterodimeric psma and cd3-binding bispecific antibodies |
| AU2024244733B2 (en) | 2023-03-31 | 2025-12-11 | AbelZeta Inc. | Bispecific chimeric antigen receptors targeting cd20 and bcma |
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-
2008
- 2008-07-07 JP JP2010515288A patent/JP2010532764A/ja active Pending
- 2008-07-07 AU AU2008287195A patent/AU2008287195A1/en not_active Abandoned
- 2008-07-07 CA CA002691819A patent/CA2691819A1/en not_active Abandoned
- 2008-07-07 EP EP08827538A patent/EP2167130A2/en not_active Withdrawn
- 2008-07-07 US US12/168,875 patent/US20090148447A1/en not_active Abandoned
- 2008-07-07 CN CN2008801052519A patent/CN101990439A/zh active Pending
- 2008-07-07 BR BRPI0814060-0A2A patent/BRPI0814060A2/pt not_active IP Right Cessation
- 2008-07-07 WO PCT/US2008/069378 patent/WO2009023386A2/en not_active Ceased
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