JP2010531354A - カルボキシ基で一置換されたプロブコール誘導体の単離方法 - Google Patents

カルボキシ基で一置換されたプロブコール誘導体の単離方法 Download PDF

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Publication number
JP2010531354A
JP2010531354A JP2010514695A JP2010514695A JP2010531354A JP 2010531354 A JP2010531354 A JP 2010531354A JP 2010514695 A JP2010514695 A JP 2010514695A JP 2010514695 A JP2010514695 A JP 2010514695A JP 2010531354 A JP2010531354 A JP 2010531354A
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JP
Japan
Prior art keywords
formula
compound
group
iii
salt
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Pending
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JP2010514695A
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English (en)
Japanese (ja)
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JP2010531354A5 (enExample
Inventor
パーカー，ジェレミー・スティーヴン
スネイプ，エヴァン・ウィリアム
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AstraZeneca AB
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AstraZeneca AB
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Publication of JP2010531354A publication Critical patent/JP2010531354A/ja
Publication of JP2010531354A5 publication Critical patent/JP2010531354A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2010514695A 2007-06-26 2008-06-25 カルボキシ基で一置換されたプロブコール誘導体の単離方法 Pending JP2010531354A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94626007P 2007-06-26 2007-06-26
PCT/SE2008/050765 WO2009002263A1 (en) 2007-06-26 2008-06-25 Process for isolating mono-carboxy substituted probucol derivates

Publications (2)

Publication Number Publication Date
JP2010531354A true JP2010531354A (ja) 2010-09-24
JP2010531354A5 JP2010531354A5 (enExample) 2011-07-07

Family

ID=40185885

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010514695A Pending JP2010531354A (ja) 2007-06-26 2008-06-25 カルボキシ基で一置換されたプロブコール誘導体の単離方法

Country Status (4)

Country Link
US (1) US20100324328A1 (enExample)
EP (1) EP2170818A1 (enExample)
JP (1) JP2010531354A (enExample)
WO (1) WO2009002263A1 (enExample)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07506373A (ja) * 1992-04-30 1995-07-13 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア プロブコールの可溶性類似体
JP2006265257A (ja) * 1997-05-14 2006-10-05 Atherogenics Inc Ｖｃａｍ−１発現を阻害する化合物および方法
WO2006116038A2 (en) * 2005-04-21 2006-11-02 Atherogenics, Inc. Process for the separation of probucol derivatives
JP2007532538A (ja) * 2004-04-09 2007-11-15 キャンブレックス チャールズ シティ インコーポレイテッド プロブコール誘導体の製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323359B1 (en) * 2000-05-02 2001-11-27 Salsbury Chemicals, Inc. Process for preparing probucol derivatives
US7345191B2 (en) * 2005-02-26 2008-03-18 Cambrex Charles City, Inc. Process for preparation of probucol derivatives

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07506373A (ja) * 1992-04-30 1995-07-13 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア プロブコールの可溶性類似体
JP2006265257A (ja) * 1997-05-14 2006-10-05 Atherogenics Inc Ｖｃａｍ−１発現を阻害する化合物および方法
JP2007532538A (ja) * 2004-04-09 2007-11-15 キャンブレックス チャールズ シティ インコーポレイテッド プロブコール誘導体の製造方法
WO2006116038A2 (en) * 2005-04-21 2006-11-02 Atherogenics, Inc. Process for the separation of probucol derivatives

Also Published As

Publication number Publication date
US20100324328A1 (en) 2010-12-23
EP2170818A1 (en) 2010-04-07
WO2009002263A1 (en) 2008-12-31

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