|
EP2137184B1
(en)
*
|
2007-04-03 |
2013-05-08 |
Array Biopharma, Inc. |
Imidazo[1,2-a]pyridine compounds as receptor tyrosine kinase inhibitors
|
|
WO2009068567A1
(en)
|
2007-11-30 |
2009-06-04 |
Novartis Ag |
C2-c5-alkyl-imidazole-bisphosphonates
|
|
TWI496779B
(zh)
|
2008-08-19 |
2015-08-21 |
Array Biopharma Inc |
作為ｐｉｍ激酶抑制劑之三唑吡啶化合物
|
|
US8895550B2
(en)
|
2008-08-19 |
2014-11-25 |
Array Biopharma Inc. |
Triazolopyridine compounds as PIM kinase inhibitors
|
|
WO2010022081A1
(en)
|
2008-08-19 |
2010-02-25 |
Array Biopharma Inc. |
Triazolopyridine compounds as pim kinase inhibitors
|
|
US8987251B2
(en)
|
2008-08-19 |
2015-03-24 |
Array Biopharma Inc. |
Triazolopyridine compounds as PIM kinase inhibitors
|
|
CA2749837C
(en)
|
2009-01-21 |
2017-07-11 |
Rigel Pharmaceuticals, Inc. |
Derivatives of n2-(3-pyridil or phenyl)-n4-(4-piperidyl)-2,4-pyrimidinediamine useful in the treatment of inflammatory, autoimmune or proliferative diseases
|
|
NZ596467A
(en)
|
2009-06-05 |
2014-01-31 |
Pfizer |
L- ( piperidin-4-yl) -pyrazole derivatives as gpr 119 modulators
|
|
PH12012500778A1
(en)
|
2009-10-30 |
2012-11-26 |
Janssen Pharmaceutica Nv |
IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVES AND THEIR USE AS PDE10 INHIBITORS
|
|
EP2332917B1
(en)
*
|
2009-11-11 |
2012-08-01 |
Sygnis Bioscience GmbH & Co. KG |
Compounds for PIM kinase inhibition and for treating malignancy
|
|
FR2952934B1
(fr)
*
|
2009-11-23 |
2012-06-22 |
Sanofi Aventis |
Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
|
|
AR080754A1
(es)
|
2010-03-09 |
2012-05-09 |
Janssen Pharmaceutica Nv |
Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10
|
|
CN103221392B
(zh)
|
2010-11-17 |
2015-06-03 |
埃科特莱茵药品有限公司 |
桥联螺[2.4]庚酯衍生物
|
|
PL2678329T3
(pl)
|
2011-02-25 |
2016-06-30 |
Array Biopharma Inc |
Związki triazolopirydyny jako inhibitory kinaz pim
|
|
EP2524915A1
(en)
|
2011-05-20 |
2012-11-21 |
Sanofi |
2-Amino-3-(imidazol-2-yl)-pyridin-4-one derivatives and their use as VEGF receptor kinase inhibitors
|
|
BR112013033375B1
(pt)
|
2011-06-27 |
2022-05-10 |
Janssen Pharmaceutica N.V |
Derivados de 1-aril-4-metil-[1,2,4]triazolo[4,3-a]quinoxa-lina, seu uso, composição farmacêutica que os compreende, processo de preparação dos mesmos, solução estéril e composto intermediário
|
|
WO2013005057A1
(en)
|
2011-07-07 |
2013-01-10 |
Centro Nacional De Investigaciones Oncológicas (Cnio) |
New compounds
|
|
WO2013007768A1
(en)
|
2011-07-13 |
2013-01-17 |
F. Hoffmann-La Roche Ag |
Tricyclic heterocyclic compounds, compositions and methods of use thereof as jak inhibitors
|
|
RS54936B1
(sr)
|
2011-10-14 |
2016-11-30 |
Ambit Biosciences Corp |
Heterociklična jedinjenja i njihova upotreba kao modulatora receptora tirozin kinaza tipa iii
|
|
MA37618B1
(fr)
|
2012-05-16 |
2017-08-31 |
Actelion Pharmaceuticals Ltd |
Dérivés pontés fluorés de spiro[2.4]heptane en tant qu'agonistes de récepteur alx
|
|
HK1206250A1
(en)
|
2012-06-26 |
2016-01-08 |
Janssen Pharmaceutica Nv |
Combinations comprising pde 2 inhibitors such as 1-aryl-4-methyl-[1,2,4] triazolo [4,3-a] quinoxaline compounds and ped 10 inhibitors for use in the treatment of neurological or metabolic disorders
|
|
WO2014009305A1
(en)
|
2012-07-09 |
2014-01-16 |
Janssen Pharmaceutica Nv |
Inhibitors of phosphodiesterase 10 enzyme
|
|
KR102092988B1
(ko)
*
|
2012-09-28 |
2020-03-25 |
벤더르빌트 유니버시티 |
선택성 bmp 저해제로써 융합된 헤테로 고리 화합물들
|
|
JP6437452B2
(ja)
|
2013-01-14 |
2018-12-12 |
インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ |
Ｐｉｍキナーゼ阻害剤として有用な二環式芳香族カルボキサミド化合物
|
|
RS60244B1
(sr)
|
2013-01-15 |
2020-06-30 |
Incyte Holdings Corp |
Jedinjenja tiazolkarboksamida i piridinkarboksamida korisna kao inhibitori pim kinaze
|
|
CN105658653A
(zh)
|
2013-08-23 |
2016-06-08 |
因赛特公司 |
可用作pim激酶抑制剂的呋喃并-和噻吩并-吡啶甲酰胺化合物
|
|
US9580418B2
(en)
|
2014-07-14 |
2017-02-28 |
Incyte Corporation |
Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
|
|
WO2016010897A1
(en)
|
2014-07-14 |
2016-01-21 |
Incyte Corporation |
Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors
|
|
CN104597194B
(zh)
*
|
2015-01-15 |
2016-07-06 |
武汉轻工大学 |
3-氯-1，2-丙二醇的高效液相色谱-荧光检测方法
|
|
WO2016196244A1
(en)
|
2015-05-29 |
2016-12-08 |
Incyte Corporation |
Pyridineamine compounds useful as pim kinase inhibitors
|
|
TWI734699B
(zh)
|
2015-09-09 |
2021-08-01 |
美商英塞特公司 |
Ｐｉｍ激酶抑制劑之鹽
|
|
US9920032B2
(en)
|
2015-10-02 |
2018-03-20 |
Incyte Corporation |
Heterocyclic compounds useful as pim kinase inhibitors
|
|
MX2020003242A
(es)
|
2017-09-22 |
2020-09-18 |
Jubilant Epipad LLC |
Compuestos heterociclicos como inhibidores de pad.
|
|
AU2018352142B2
(en)
|
2017-10-18 |
2022-08-25 |
Jubilant Epipad LLC |
Imidazo-pyridine compounds as PAD inhibitors
|
|
KR20200085836A
(ko)
|
2017-11-06 |
2020-07-15 |
주빌런트 프로델 엘엘씨 |
Pd1/pd-l1 활성화 억제제로서의 피리미딘 유도체
|
|
BR112020010322A2
(pt)
|
2017-11-24 |
2020-11-17 |
Jubilant Episcribe Llc |
composto da fórmula i; composto da fórmula ia; composto da fórmula ib; processo de preparação de compostos da fórmula i; composição farmacêutica; método para o tratamento e/ou prevenção de várias doenças; uso dos compostos; método para o tratamento de câncer; e método para o tratamento e/ou prevenção de uma afecção mediada por prmt5 ou um distúrbio proliferativo ou câncer
|
|
AR113922A1
(es)
|
2017-12-08 |
2020-07-01 |
Incyte Corp |
Terapia de combinación de dosis baja para el tratamiento de neoplasias mieloproliferativas
|
|
SG11202008950PA
(en)
|
2018-03-13 |
2020-10-29 |
Jubilant Prodel LLC |
Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation
|
|
WO2019178383A1
(en)
|
2018-03-14 |
2019-09-19 |
Vanderbilt University |
Inhibition of bmp signaling, compounds, compositions and uses thereof
|
|
CN110833556A
(zh)
*
|
2018-08-15 |
2020-02-25 |
广西梧州制药（集团）股份有限公司 |
吡唑并嘧啶衍生物在治疗肝纤维化的用途
|
|
AU2021320860A1
(en)
*
|
2020-08-05 |
2023-02-23 |
The General Hospital Corporation |
Salt inducible kinase inhibitors
|