JP2010522218A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010522218A5 JP2010522218A5 JP2010500035A JP2010500035A JP2010522218A5 JP 2010522218 A5 JP2010522218 A5 JP 2010522218A5 JP 2010500035 A JP2010500035 A JP 2010500035A JP 2010500035 A JP2010500035 A JP 2010500035A JP 2010522218 A5 JP2010522218 A5 JP 2010522218A5
- Authority
- JP
- Japan
- Prior art keywords
- dihydro
- oxo
- carbonyl
- amino
- cyclopropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92001807P | 2007-03-26 | 2007-03-26 | |
| PCT/CA2008/000561 WO2008116304A1 (en) | 2007-03-26 | 2008-03-25 | Naphthalene and quinoline sulfonylurea derivatives as ep4 receptor antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010522218A JP2010522218A (ja) | 2010-07-01 |
| JP2010522218A5 true JP2010522218A5 (OSRAM) | 2011-05-06 |
Family
ID=39787996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010500035A Pending JP2010522218A (ja) | 2007-03-26 | 2008-03-25 | Ｅｐ４受容体アンタゴニストとしてのナフタレン及びキノリンスルホニル尿素誘導体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8003661B2 (OSRAM) |
| EP (1) | EP2125724B1 (OSRAM) |
| JP (1) | JP2010522218A (OSRAM) |
| CN (1) | CN101636385B (OSRAM) |
| AU (1) | AU2008232265B2 (OSRAM) |
| CA (1) | CA2681146A1 (OSRAM) |
| WO (1) | WO2008116304A1 (OSRAM) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012503605A (ja) * | 2008-09-25 | 2012-02-09 | メルク カナダ インコーポレイテッド | Ｅｐ４受容体アンタゴニストとしてのベータ−カルボリンスルホニルウレア誘導体 |
| WO2010087425A1 (ja) | 2009-01-30 | 2010-08-05 | 国立大学法人京都大学 | 前立腺癌の進行抑制剤および進行抑制方法 |
| US9295665B2 (en) | 2013-03-12 | 2016-03-29 | Allergan, Inc. | Inhibition of neovascularization by simultaneous inhibition of prostanoid IP and EP4 receptors |
| CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
| CN110621671A (zh) | 2017-05-18 | 2019-12-27 | 爱杜西亚药品有限公司 | 作为pge2受体调节剂的苯并呋喃及苯并噻吩衍生物 |
| LT3625224T (lt) | 2017-05-18 | 2021-10-25 | Idorsia Pharmaceuticals Ltd | N-pakeistieji indolo dariniai |
| TW201900180A (zh) | 2017-05-18 | 2019-01-01 | 瑞士商愛杜西亞製藥有限公司 | 嘧啶衍生物 |
| LT3625222T (lt) | 2017-05-18 | 2021-11-10 | Idorsia Pharmaceuticals Ltd | Fenilo dariniai, kaip pge2 receptoriaus moduliatoriai |
| PT3625228T (pt) | 2017-05-18 | 2021-09-16 | Idorsia Pharmaceuticals Ltd | Derivados de pirimidina como moduladores dos recetores de pge2 |
| JPWO2022102731A1 (OSRAM) | 2020-11-13 | 2022-05-19 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9417532D0 (en) | 1994-08-31 | 1994-10-19 | Zeneca Ltd | Aromatic compounds |
| GB9420557D0 (en) | 1994-10-12 | 1994-11-30 | Zeneca Ltd | Aromatic compounds |
| EP0752421B1 (en) | 1995-07-07 | 2005-10-12 | AstraZeneca AB | Ortho-substituted aromatic compounds, containing three (het)aryl moieties, their preparation and their use as prostaglandin E2-(PGE2)-antagonists |
| HN2001000224A (es) * | 2000-10-19 | 2002-06-13 | Pfizer | Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos. |
| GB0031302D0 (en) * | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Napthalene derivatives |
| EP1495005A1 (en) * | 2002-04-12 | 2005-01-12 | Pfizer Japan Inc. | Pyrazole compounds as anti-inflammatory and analgesic agents |
| AU2006246930C1 (en) | 2005-05-19 | 2012-01-19 | Merck Canada Inc. | Quinoline derivatives as EP4 antagonists |
-
2008
- 2008-03-25 CA CA002681146A patent/CA2681146A1/en not_active Abandoned
- 2008-03-25 EP EP08733664.0A patent/EP2125724B1/en active Active
- 2008-03-25 AU AU2008232265A patent/AU2008232265B2/en not_active Ceased
- 2008-03-25 CN CN2008800089997A patent/CN101636385B/zh not_active Expired - Fee Related
- 2008-03-25 US US12/529,271 patent/US8003661B2/en active Active
- 2008-03-25 WO PCT/CA2008/000561 patent/WO2008116304A1/en not_active Ceased
- 2008-03-25 JP JP2010500035A patent/JP2010522218A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010522218A5 (OSRAM) | ||
| JP5941095B2 (ja) | Ａｔｐ結合カセット輸送体モジュレータ | |
| JP6021805B2 (ja) | 腫瘍治療剤 | |
| TWI598098B (zh) | 脂質異常症治療劑 | |
| JP2015524472A5 (OSRAM) | ||
| JP2010503688A5 (OSRAM) | ||
| JP2016512825A5 (OSRAM) | ||
| CN107921031A (zh) | 给予谷氨酰胺酶抑制剂的方法 | |
| JP2015511638A5 (OSRAM) | ||
| JP2020512337A5 (OSRAM) | ||
| EA032028B1 (ru) | СТИМУЛЯТОРЫ рГЦ | |
| JP2016534124A5 (OSRAM) | ||
| CN104023715B (zh) | 激酶抑制剂的副作用降低剂 | |
| JP2014505107A5 (OSRAM) | ||
| US20110065676A1 (en) | Combination therapies comprising par1 antagonists with nar agonists | |
| JP2011509301A5 (OSRAM) | ||
| JP2011509302A5 (OSRAM) | ||
| RU2018131775A (ru) | 6-арил-4-морфолин-1-илпиридоны, пригодные для лечения рака или диабета | |
| JP2016525104A5 (OSRAM) | ||
| CN1516600A (zh) | 用于治疗肿瘤疾病的联合药物 | |
| TW201202255A (en) | Novel composition for the prevention and/or treatment of thromboembolism | |
| JP2019501134A5 (OSRAM) | ||
| RU2015126293A (ru) | Производные тиазола в качестве ингибиторов тирозинкиназы брутона | |
| RU2014128387A (ru) | Ингибиторы рi3к для лечения фиброзных заболеваний | |
| JP2018522915A5 (OSRAM) |