JP2010520761A - 間葉系幹細胞亜集団および破骨細胞に対するマーカー、抗体および組換えscFv - Google Patents

間葉系幹細胞亜集団および破骨細胞に対するマーカー、抗体および組換えscFv Download PDF

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JP2010520761A
JP2010520761A JP2009553137A JP2009553137A JP2010520761A JP 2010520761 A JP2010520761 A JP 2010520761A JP 2009553137 A JP2009553137 A JP 2009553137A JP 2009553137 A JP2009553137 A JP 2009553137A JP 2010520761 A JP2010520761 A JP 2010520761A
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Prior art keywords
seq
antibody
cells
scfv
polypeptide
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JP2009553137A
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Japanese (ja)
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JP2010520761A5 (enExample
Inventor
タイロン ビリャラード バウズ,
ウド グライサー,
ウィリアム ジェームス ジョナサン フィンレイ,
ティモシー オブライアン,
フランク バリー,
Original Assignee
ナショナル ユニバーシティー オブ アイルランド, ゴールウェイ
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Publication of JP2010520761A publication Critical patent/JP2010520761A/ja
Publication of JP2010520761A5 publication Critical patent/JP2010520761A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2009553137A 2007-03-12 2008-03-12 間葉系幹細胞亜集団および破骨細胞に対するマーカー、抗体および組換えscFv Pending JP2010520761A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IE20070170 2007-03-12
IE20080015 2008-01-11
PCT/EP2008/052959 WO2008110578A2 (en) 2007-03-12 2008-03-12 Markers, antibodies and recombinant scfvs for mesenchymal stem cell-sub-populations and osteoclasts

Publications (2)

Publication Number Publication Date
JP2010520761A true JP2010520761A (ja) 2010-06-17
JP2010520761A5 JP2010520761A5 (enExample) 2012-05-10

Family

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JP2009553137A Pending JP2010520761A (ja) 2007-03-12 2008-03-12 間葉系幹細胞亜集団および破骨細胞に対するマーカー、抗体および組換えscFv

Country Status (6)

Country Link
US (1) US20100062038A1 (enExample)
EP (1) EP2118272A2 (enExample)
JP (1) JP2010520761A (enExample)
AU (1) AU2008225828A1 (enExample)
CA (1) CA2688121A1 (enExample)
WO (1) WO2008110578A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7611540B2 (en) 2007-05-01 2009-11-03 Moximed, Inc. Extra-articular implantable mechanical energy absorbing systems and implantation method
FR2953023B1 (fr) * 2009-11-23 2011-12-09 Commissariat Energie Atomique Utilisation d'une isoforme d'hla-g comme marqueur de l'osteogenese

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002022638A1 (en) * 2000-09-12 2002-03-21 Human Genome Sciences, Inc. 22 human secreted proteins

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002022638A1 (en) * 2000-09-12 2002-03-21 Human Genome Sciences, Inc. 22 human secreted proteins

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6013001402; Circ. J. Vol.71, No.Supplement 1, 20070301, p.142 FRS-091 *
JPN6013001405; Hybridoma Vol.24, No.2, 2005, p.92-97 *

Also Published As

Publication number Publication date
US20100062038A1 (en) 2010-03-11
CA2688121A1 (en) 2008-09-18
WO2008110578A3 (en) 2009-01-15
EP2118272A2 (en) 2009-11-18
AU2008225828A1 (en) 2008-09-18
WO2008110578A2 (en) 2008-09-18

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