JP2010519196A - 経粘膜送達を高めるための組成物および方法 - Google Patents

経粘膜送達を高めるための組成物および方法 Download PDF

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JP2010519196A
JP2010519196A JP2009549493A JP2009549493A JP2010519196A JP 2010519196 A JP2010519196 A JP 2010519196A JP 2009549493 A JP2009549493 A JP 2009549493A JP 2009549493 A JP2009549493 A JP 2009549493A JP 2010519196 A JP2010519196 A JP 2010519196A
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amount
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composition
oil
phenylalanine
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JP2010519196A5 (enExample
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ヨセフ ルビンシュタイン
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ダーマ−ヤング リミテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Botany (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2009549493A 2007-02-15 2008-02-14 経粘膜送達を高めるための組成物および方法 Pending JP2010519196A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90134507P 2007-02-15 2007-02-15
PCT/IL2008/000192 WO2008099397A2 (en) 2007-02-15 2008-02-14 Compositions and methods for enhancing transmucosal delivery

Publications (2)

Publication Number Publication Date
JP2010519196A true JP2010519196A (ja) 2010-06-03
JP2010519196A5 JP2010519196A5 (enExample) 2011-03-31

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JP2009549493A Pending JP2010519196A (ja) 2007-02-15 2008-02-14 経粘膜送達を高めるための組成物および方法

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US (1) US20100086495A1 (enExample)
EP (1) EP2114384A4 (enExample)
JP (1) JP2010519196A (enExample)
KR (1) KR20090125100A (enExample)
CN (1) CN101754755A (enExample)
AU (1) AU2008215771A1 (enExample)
BR (1) BRPI0807943A2 (enExample)
CA (1) CA2678500A1 (enExample)
WO (1) WO2008099397A2 (enExample)
ZA (1) ZA200905697B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015515991A (ja) * 2012-05-03 2015-06-04 ビュシャン,ラジブ 輸送エンハンサーとしてメチルスルホニルメタンを備えた金属モジュレーターを使用する、炎症疾患の処置及び口腔衛生の改善
JP2016504405A (ja) * 2013-01-14 2016-02-12 ロッセロ ラファエル ガレヌス製剤の有効成分の投与剤形

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US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US20100209419A1 (en) * 2008-08-15 2010-08-19 Rajiv Bhushan Method and formulation for treating adverse biological conditions
WO2010144865A2 (en) 2009-06-12 2010-12-16 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
TR200907338A1 (tr) * 2009-09-28 2011-04-21 Yed�Tepe �N�Vers�Tes� Doğal bileşenler içeren bir film şeridi.
KR101171832B1 (ko) 2009-10-30 2012-08-14 박경식 부작용을 제거한 장기간 복용 차 및 그 조성물
TR201103770A1 (tr) * 2011-04-19 2012-11-21 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Nimesulid ve metilsülfonilmetanin topikalfarmasötik bileşimleri.
WO2014024193A1 (en) * 2012-08-07 2014-02-13 Prodel Pharma Ltd. Compositions and methods for rapid transmucosal delivery of pharmaceutical ingredients
WO2014100777A2 (en) 2012-12-20 2014-06-26 Rajiv Bhushan Antimicrobial compositions
US20160095868A1 (en) * 2013-04-17 2016-04-07 Morris Notelovitz Composition, formulations and methods of making and using botanicals and natural compounds for the promotion of healthy brain aging
CN104352461B (zh) * 2013-04-28 2017-07-14 南京海融医药科技股份有限公司 他达拉非的口服药物制剂
US9855234B2 (en) 2014-07-08 2018-01-02 Insys Development Company, Inc. Diclofenac sublingual spray
KR101484481B1 (ko) * 2014-08-07 2015-01-20 주식회사 다림바이오텍 Pde-5 저해제를 포함하는 설하분무제의 제조방법 및 이에 의하여 제조된 설하분무용 조성물
NL2015957B1 (en) * 2015-12-14 2017-06-29 Scala Pharma B V Compositions and methods for inducing beige or brown fat tissue.
US9855227B2 (en) 2015-12-18 2018-01-02 The Procter & Gamble Company Quick dissolving diphenhydramine oral dosage form
CN111956652A (zh) * 2020-08-21 2020-11-20 重庆康刻尔制药股份有限公司 一种西地那非口腔膜剂药物组合及其制备方法
AU2021392316B2 (en) * 2020-12-04 2025-02-27 Inovobiologic, Inc. Eutectic matrix for nutraceutical compositions
WO2023129171A1 (en) * 2021-12-31 2023-07-06 LIVIONEX, Inc. Formulations of anti-inflammatory agents comprising msm with enhanced solubility in water

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JPH10503482A (ja) * 1994-06-20 1998-03-31 ケーヴィ・ファーマスーティカル・カンパニー 改良された長時間作用型胃腸・食道保護剤
WO1999061042A1 (en) * 1998-05-28 1999-12-02 Vickery Brice E Compositions and methods for enhancing protein anabolism and detoxification
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JP2006290792A (ja) * 2005-04-11 2006-10-26 Tm East:Kk 抗炎症剤

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JPH10503482A (ja) * 1994-06-20 1998-03-31 ケーヴィ・ファーマスーティカル・カンパニー 改良された長時間作用型胃腸・食道保護剤
WO1999061042A1 (en) * 1998-05-28 1999-12-02 Vickery Brice E Compositions and methods for enhancing protein anabolism and detoxification
JP2006514696A (ja) * 2002-12-20 2006-05-11 チャクシュ・リサーチ・インコーポレーテッド 眼球の症状の予防及び治療のための眼科用製剤
JP2006290792A (ja) * 2005-04-11 2006-10-26 Tm East:Kk 抗炎症剤

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015515991A (ja) * 2012-05-03 2015-06-04 ビュシャン,ラジブ 輸送エンハンサーとしてメチルスルホニルメタンを備えた金属モジュレーターを使用する、炎症疾患の処置及び口腔衛生の改善
JP2019206572A (ja) * 2012-05-03 2019-12-05 ビュシャン,ラジブ 輸送エンハンサーとしてメチルスルホニルメタンを備えた金属モジュレーターを使用する、炎症疾患の処置及び口腔衛生の改善
JP2016504405A (ja) * 2013-01-14 2016-02-12 ロッセロ ラファエル ガレヌス製剤の有効成分の投与剤形

Also Published As

Publication number Publication date
CA2678500A1 (en) 2008-08-21
KR20090125100A (ko) 2009-12-03
ZA200905697B (en) 2010-10-27
EP2114384A2 (en) 2009-11-11
WO2008099397A3 (en) 2010-01-07
US20100086495A1 (en) 2010-04-08
CN101754755A (zh) 2010-06-23
EP2114384A4 (en) 2012-02-01
AU2008215771A1 (en) 2008-08-21
BRPI0807943A2 (pt) 2014-10-21
WO2008099397A2 (en) 2008-08-21

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