JP2010519183A - 生理溶液の溶出のためのタンパク質の沈殿を用いる重合 - Google Patents

生理溶液の溶出のためのタンパク質の沈殿を用いる重合 Download PDF

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Publication number
JP2010519183A
JP2010519183A JP2009549095A JP2009549095A JP2010519183A JP 2010519183 A JP2010519183 A JP 2010519183A JP 2009549095 A JP2009549095 A JP 2009549095A JP 2009549095 A JP2009549095 A JP 2009549095A JP 2010519183 A JP2010519183 A JP 2010519183A
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Japan
Prior art keywords
hydrogel
drug
precursor
solution
precipitation
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Abandoned
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JP2009549095A
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Japanese (ja)
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JP2010519183A5 (enExample
Inventor
エス.サウフネイ アマルプレエト
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Incept LLC
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Incept LLC
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Publication of JP2010519183A publication Critical patent/JP2010519183A/ja
Publication of JP2010519183A5 publication Critical patent/JP2010519183A5/ja
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1841Transforming growth factor [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1875Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/363Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polyethers (AREA)
JP2009549095A 2007-02-06 2008-02-06 生理溶液の溶出のためのタンパク質の沈殿を用いる重合 Abandoned JP2010519183A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89989807P 2007-02-06 2007-02-06
PCT/US2008/001577 WO2008097581A1 (en) 2007-02-06 2008-02-06 Polymerization with precipitation of proteins for elution in physiological solution

Publications (2)

Publication Number Publication Date
JP2010519183A true JP2010519183A (ja) 2010-06-03
JP2010519183A5 JP2010519183A5 (enExample) 2011-03-24

Family

ID=39676361

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009549095A Abandoned JP2010519183A (ja) 2007-02-06 2008-02-06 生理溶液の溶出のためのタンパク質の沈殿を用いる重合

Country Status (6)

Country Link
US (1) US20080187568A1 (enExample)
EP (1) EP2121057A4 (enExample)
JP (1) JP2010519183A (enExample)
AU (1) AU2008214319A1 (enExample)
CA (1) CA2677532A1 (enExample)
WO (1) WO2008097581A1 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014520168A (ja) * 2011-05-09 2014-08-21 ワシントン ステート ユニバーシティ リサーチ ファウンデーション 可撓固体導体
JPWO2014034884A1 (ja) * 2012-08-31 2016-08-08 国立大学法人北陸先端科学技術大学院大学 凍結保存可能な細胞足場材料
WO2016143647A1 (ja) * 2015-03-10 2016-09-15 国立大学法人 東京大学 ゲル前駆体クラスターを用いた低濃度ゲルの製造方法、及び当該製造方法により得られるゲル
WO2020027016A1 (ja) * 2018-07-31 2020-02-06 国立大学法人 東京大学 スポンジ様の多孔体構造を有する高分子ゲル
JP2023510380A (ja) * 2020-01-16 2023-03-13 香港科技大学 標的剤の放出制御のための組成物及び方法

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PL2459220T3 (pl) * 2009-07-31 2021-03-08 Ascendis Pharma A/S Biodegradowalne nierozpuszczalne w wodzie hydrożele na bazie poli(glikolu etylenowego)
WO2011065916A1 (en) 2009-11-24 2011-06-03 Agency For Science, Technology And Research Crosslinking branched molecule through thiol-disulfide exchange to form hydrogel
EP3583960A1 (en) 2009-12-15 2019-12-25 Incept, LLC Implants and biodegradable fiducial markers
EP2380920A1 (en) 2010-04-22 2011-10-26 QGel SA Hydrogel precursor formulation and production process thereof
EP2438930A1 (en) 2010-09-17 2012-04-11 Sanofi-Aventis Deutschland GmbH Prodrugs comprising an exendin linker conjugate
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
CN104349769B (zh) 2011-12-05 2018-10-09 因赛普特有限责任公司 医用有机凝胶方法和组合物
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SG10201903210WA (en) 2014-12-15 2019-05-30 Univ Johns Hopkins Sunitinib Formulations and Methods for Use Thereof in Treatment of Ocular Disorders
HK1257499A1 (zh) 2015-11-12 2019-10-25 Graybug Vision, Inc. 用於治疗的聚集性微粒
MX2019013363A (es) 2017-05-10 2020-01-13 Graybug Vision Inc Microparticulas de liberacion extendida y suspensiones de las mismas para terapia medica.
CN116507330A (zh) * 2020-11-12 2023-07-28 普拉曼德有限责任公司 用于子宫内使用的原位形成的水凝胶和组合物设计
US12343454B2 (en) * 2020-11-12 2025-07-01 Pramand LLC Hydrogels formed in situ and composition design for intrauterine use

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Cited By (11)

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Publication number Priority date Publication date Assignee Title
JP2014520168A (ja) * 2011-05-09 2014-08-21 ワシントン ステート ユニバーシティ リサーチ ファウンデーション 可撓固体導体
US9614250B2 (en) 2011-05-09 2017-04-04 Empire Technology Development Llc Flexible solid state conductors including polymer mixed with protein
JPWO2014034884A1 (ja) * 2012-08-31 2016-08-08 国立大学法人北陸先端科学技術大学院大学 凍結保存可能な細胞足場材料
WO2016143647A1 (ja) * 2015-03-10 2016-09-15 国立大学法人 東京大学 ゲル前駆体クラスターを用いた低濃度ゲルの製造方法、及び当該製造方法により得られるゲル
JPWO2016143647A1 (ja) * 2015-03-10 2017-12-21 国立大学法人 東京大学 ゲル前駆体クラスターを用いた低濃度ゲルの製造方法、及び当該製造方法により得られるゲル
US10550225B2 (en) 2015-03-10 2020-02-04 The University Of Tokyo Process for producing low-concentration gel using gel-precursor clusters, and gel obtained by said production process
WO2020027016A1 (ja) * 2018-07-31 2020-02-06 国立大学法人 東京大学 スポンジ様の多孔体構造を有する高分子ゲル
JPWO2020027016A1 (ja) * 2018-07-31 2021-08-10 国立大学法人 東京大学 スポンジ様の多孔体構造を有する高分子ゲル
JP7272672B2 (ja) 2018-07-31 2023-05-12 国立大学法人 東京大学 スポンジ様の多孔体構造を有する高分子ゲル
US12227642B2 (en) 2018-07-31 2025-02-18 The University Of Tokyo Polymer gel having sponge-like porous structure
JP2023510380A (ja) * 2020-01-16 2023-03-13 香港科技大学 標的剤の放出制御のための組成物及び方法

Also Published As

Publication number Publication date
AU2008214319A1 (en) 2008-08-14
EP2121057A4 (en) 2012-10-10
WO2008097581A1 (en) 2008-08-14
EP2121057A1 (en) 2009-11-25
US20080187568A1 (en) 2008-08-07
CA2677532A1 (en) 2008-08-14

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