JP2010519180A5 - - Google Patents
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- Publication number
- JP2010519180A5 JP2010519180A5 JP2009546652A JP2009546652A JP2010519180A5 JP 2010519180 A5 JP2010519180 A5 JP 2010519180A5 JP 2009546652 A JP2009546652 A JP 2009546652A JP 2009546652 A JP2009546652 A JP 2009546652A JP 2010519180 A5 JP2010519180 A5 JP 2010519180A5
- Authority
- JP
- Japan
- Prior art keywords
- molecule
- disease
- moshiku
- crohn
- plasma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000011231 Crohn disease Diseases 0.000 claims 5
- 206010009887 colitis Diseases 0.000 claims 4
- 230000002757 inflammatory effect Effects 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 208000000668 Chronic Pancreatitis Diseases 0.000 claims 3
- 206010009900 Colitis ulcerative Diseases 0.000 claims 3
- 206010033649 Pancreatitis chronic Diseases 0.000 claims 3
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 3
- 238000003745 diagnosis Methods 0.000 claims 3
- 230000028993 immune response Effects 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 238000002560 therapeutic procedure Methods 0.000 claims 3
- 208000023275 Autoimmune disease Diseases 0.000 claims 2
- 108060003951 Immunoglobulin Proteins 0.000 claims 2
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000001124 body fluid Anatomy 0.000 claims 2
- 239000010839 body fluid Substances 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 230000008105 immune reaction Effects 0.000 claims 2
- 102000018358 immunoglobulin Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 238000007363 ring formation reaction Methods 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 206010008609 Cholangitis sclerosing Diseases 0.000 claims 1
- 208000004232 Enteritis Diseases 0.000 claims 1
- 208000027761 Hepatic autoimmune disease Diseases 0.000 claims 1
- 238000007792 addition Methods 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- 230000001363 autoimmune Effects 0.000 claims 1
- 208000037976 chronic inflammation Diseases 0.000 claims 1
- 208000037893 chronic inflammatory disorder Diseases 0.000 claims 1
- 235000018417 cysteine Nutrition 0.000 claims 1
- 150000001945 cysteines Chemical class 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 210000003608 fece Anatomy 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 claims 1
- 238000010166 immunofluorescence Methods 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 230000000968 intestinal effect Effects 0.000 claims 1
- 208000019423 liver disease Diseases 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 201000000742 primary sclerosing cholangitis Diseases 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 208000010157 sclerosing cholangitis Diseases 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 230000005945 translocation Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007004909.0 | 2007-01-26 | ||
| EP07090010A EP1950222A1 (de) | 2007-01-26 | 2007-01-26 | Verfahren zum Nachweis von Antikörpern aus Körperflüssigkeiten durch eine Immunreaktion mit Glykoprotein 2 (GP2) aus zymogenen Granula des Pankreas zur Differentialdiagnose von entzündlichen Darmerkrankungen und chronischer Pankreatitis |
| DE200710004909 DE102007004909A1 (de) | 2007-01-26 | 2007-01-26 | Verfahren zum Nachweis von Antikörpern aus Körperflüssigkeiten durch eine Immunreaktion mit Glykoprotein 2(GP2) aus zymogenen Granula des Pankreas zur Differentialdiagnose von entzündlichen Darmerkrankungen und chronischer Pankreatitis |
| EP07090010.5 | 2007-01-26 | ||
| PCT/DE2008/000183 WO2008089756A2 (de) | 2007-01-26 | 2008-01-28 | Verfahren zum nachweis von antikörpern aus körperflüssigkeiten durch eine immunreaktion mit glykoprotein 2 (gp2) aus zymogenen granula des pankreas zur differentialdiagnose von entzündlichen darmerkrankungen und chronischer pankreatitis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010519180A JP2010519180A (ja) | 2010-06-03 |
| JP2010519180A5 true JP2010519180A5 (cg-RX-API-DMAC7.html) | 2012-01-12 |
| JP5603083B2 JP5603083B2 (ja) | 2014-10-08 |
Family
ID=39644915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009546652A Active JP5603083B2 (ja) | 2007-01-26 | 2008-01-28 | 炎症性大腸炎及び慢性膵炎の診断のために、膵臓の酵素原顆粒由来の糖タンパク質２（ｇｐ２）との免疫反応を介して体液から抗体を検出する方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8058019B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2126582B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5603083B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101283710B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN101611320B (cg-RX-API-DMAC7.html) |
| AT (1) | ATE515704T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008209176B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2674021C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2126582T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2369544T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL2126582T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2126582E (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008089756A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7195759B2 (en) * | 2001-06-06 | 2007-03-27 | The University Of Manitoba | Therapeutic uses of glandular kallikrein |
| GB0905076D0 (en) * | 2009-03-24 | 2009-05-06 | Total Scient Ltd | Diagnostic kits and methods |
| EP2521915A4 (en) * | 2010-01-04 | 2013-05-29 | Mayo Foundation | PERIPHERINE-SPECIFIC AUTOANTIKÖRPER AS A MARKER FOR NEUROLOGICAL AND ENDOCRINOLOGICAL DISEASES |
| US20130315891A1 (en) | 2012-05-25 | 2013-11-28 | Matthew Charles | Formulations of human tissue kallikrein-1 for parenteral delivery and related methods |
| HUE032613T2 (en) | 2012-06-04 | 2017-10-30 | Diamedica Therapeutics Inc | Human tissue kallikrein 1 is glycosylated isoforms |
| US11340235B2 (en) | 2014-02-28 | 2022-05-24 | Ga Generic Assays Gmbh | GP2 isoforms and their use in autoantibody capture |
| ES2790577T3 (es) * | 2014-02-28 | 2020-10-28 | Ga Generic Assays Gmbh | Isoformas de GP2 y su uso en la captura de autoanticuerpos |
| EP3299818B1 (en) * | 2016-09-26 | 2019-12-04 | GA Generic Assays GmbH | Method for the diagnosis of acute pancreatitis (ap) by detection of glycoprotein 2 isoform alpha (gp2a) |
| CN110073217A (zh) * | 2016-10-04 | 2019-07-30 | 豪夫迈·罗氏有限公司 | 用于鉴定合成分类器的系统和方法 |
| CN110446501A (zh) | 2017-03-09 | 2019-11-12 | 代阿麦迪卡股份有限公司 | 组织激肽释放酶1的剂型 |
| EP3477300A1 (de) * | 2017-10-25 | 2019-05-01 | Euroimmun Medizinische Labordiagnostika AG | Zellulose-basierter immunadsorber |
| US20220331357A1 (en) * | 2019-09-27 | 2022-10-20 | Duke University | Compositions and methods for the prevention and treatment of pancreatitis |
| CN110806485A (zh) * | 2019-11-12 | 2020-02-18 | 广州医科大学附属第二医院 | 一种胶质纤维酸性蛋白抗体检测试剂盒及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5663315A (en) * | 1994-12-06 | 1997-09-02 | Alphagene, Inc. | Isolated DNA encoding human GP2 |
| DE19630557C2 (de) * | 1996-07-18 | 1998-07-02 | Schuppan Detlef Priv Doz Dr Dr | Verfahren zum Nachweis von Antikörpern aus Körperflüssigkeiten durch eine Immunreaktion mit Gewebe-Transglutaminase (tTG) sowie die Verwendung von tTG in Diagnose und Therapie |
| US6100098A (en) | 1997-02-18 | 2000-08-08 | Mcgill University | Anti-AGE IgG and uses thereof for the diagnosis of severe disease |
| AU2001271284A1 (en) * | 2000-06-07 | 2001-12-17 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of pancreatic cancer |
| JP2004005319A (ja) | 2002-04-24 | 2004-01-08 | Japan Science & Technology Corp | 遺伝子データベース作成方法、遺伝子データベース作成装置、遺伝子データベース作成プログラム、および遺伝子データベース作成プログラムを記録したコンピュータ読み取り可能な記録媒体 |
| US20070275422A1 (en) * | 2004-07-26 | 2007-11-29 | The Board Of Trustees Of The Leland Stanford Jr. U | Methods and Compositions for Detecting Pancreatic Disease |
-
2008
- 2008-01-28 JP JP2009546652A patent/JP5603083B2/ja active Active
- 2008-01-28 PT PT08706848T patent/PT2126582E/pt unknown
- 2008-01-28 CN CN2008800030495A patent/CN101611320B/zh active Active
- 2008-01-28 ES ES08706848T patent/ES2369544T3/es active Active
- 2008-01-28 EP EP08706848A patent/EP2126582B1/de active Active
- 2008-01-28 WO PCT/DE2008/000183 patent/WO2008089756A2/de not_active Ceased
- 2008-01-28 AU AU2008209176A patent/AU2008209176B2/en active Active
- 2008-01-28 AT AT08706848T patent/ATE515704T1/de active
- 2008-01-28 US US12/523,997 patent/US8058019B2/en active Active
- 2008-01-28 DK DK08706848.2T patent/DK2126582T3/da active
- 2008-01-28 KR KR1020097014809A patent/KR101283710B1/ko active Active
- 2008-01-28 PL PL08706848T patent/PL2126582T3/pl unknown
- 2008-01-28 CA CA2674021A patent/CA2674021C/en active Active
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