JP2010518020A5 - - Google Patents
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- JP2010518020A5 JP2010518020A5 JP2009548460A JP2009548460A JP2010518020A5 JP 2010518020 A5 JP2010518020 A5 JP 2010518020A5 JP 2009548460 A JP2009548460 A JP 2009548460A JP 2009548460 A JP2009548460 A JP 2009548460A JP 2010518020 A5 JP2010518020 A5 JP 2010518020A5
- Authority
- JP
- Japan
- Prior art keywords
- rab
- doc
- antigen
- coh
- cohesin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88802907P | 2007-02-02 | 2007-02-02 | |
| US60/888,029 | 2007-02-02 | ||
| PCT/US2008/052714 WO2008097817A2 (en) | 2007-02-02 | 2008-01-31 | Multivariable antigens complexed with targeting humanized monoclonal antibody |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010518020A JP2010518020A (ja) | 2010-05-27 |
| JP2010518020A5 true JP2010518020A5 (cg-RX-API-DMAC7.html) | 2011-03-17 |
| JP5543785B2 JP5543785B2 (ja) | 2014-07-09 |
Family
ID=39682338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009548460A Expired - Fee Related JP5543785B2 (ja) | 2007-02-02 | 2008-01-31 | ヒト化ターゲティングモノクローナル抗体と複合体を形成する複数の可変抗原 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US7786267B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2684889A3 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5543785B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20090114425A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101657464A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008214077B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0807344A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2715042C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2114985T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2536900T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL200092A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2009008143A (cg-RX-API-DMAC7.html) |
| NZ (2) | NZ592859A (cg-RX-API-DMAC7.html) |
| TW (1) | TW200846371A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008097817A2 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200905447B (cg-RX-API-DMAC7.html) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI422594B (zh) | 2007-02-02 | 2014-01-11 | Baylor Res Inst | 經由樹狀細胞去唾液酸糖蛋白受體(dc-asgpr)接合抗原呈現細胞之藥劑 |
| KR20090114430A (ko) | 2007-02-02 | 2009-11-03 | 베일러 리서치 인스티튜트 | 항원-제시 세포 상에서 발현된 dcir에 대한 항원 표적화에 기초한 백신 |
| CN101657464A (zh) * | 2007-02-02 | 2010-02-24 | 贝勒研究院 | 与靶向人源化单克隆抗体复合的多变量抗原 |
| MX2009008926A (es) * | 2007-02-23 | 2009-09-14 | Baylor Res Inst | Aplicaciones terapeuticas de activacion de celulas que presentan antigeno humano por medio de detectina a-1. |
| NZ595319A (en) * | 2007-02-23 | 2012-09-28 | Baylor Res Inst | Activation of human antigen-presenting cells through clec-6 |
| US8557243B2 (en) | 2008-01-03 | 2013-10-15 | The Scripps Research Institute | EFGR antibodies comprising modular recognition domains |
| US8574577B2 (en) | 2008-01-03 | 2013-11-05 | The Scripps Research Institute | VEGF antibodies comprising modular recognition domains |
| KR101658247B1 (ko) | 2008-01-03 | 2016-09-22 | 더 스크립스 리서치 인스티튜트 | 모듈 인식 도메인을 통한 항체 표적화 |
| US8557242B2 (en) | 2008-01-03 | 2013-10-15 | The Scripps Research Institute | ERBB2 antibodies comprising modular recognition domains |
| US8454960B2 (en) | 2008-01-03 | 2013-06-04 | The Scripps Research Institute | Multispecific antibody targeting and multivalency through modular recognition domains |
| EP2307443B1 (en) * | 2008-08-07 | 2013-10-02 | Yeda Research And Development Company Ltd. | Affinity purification by cohesin-dockerin interaction |
| AU2010222942B2 (en) | 2009-03-10 | 2013-01-10 | Baylor Research Institute | Anti-CD40 antibodies and uses thereof |
| DK2406289T3 (en) * | 2009-03-10 | 2017-05-01 | Baylor Res Inst | ANTIGEN PRESENTING CELL TARGETED ANTIVIRUS VACCINES |
| CN102770457A (zh) * | 2009-03-10 | 2012-11-07 | 贝勒研究院 | 靶向抗原呈递细胞的疫苗 |
| US9097713B2 (en) * | 2009-09-02 | 2015-08-04 | The United States Of America As Represented By The Secretary Of The Army On Behalf Of Usamrmc | Monoclonal antibodies against glycoprotein of Ebola sudan boniface virus |
| EP2477655A4 (en) | 2009-09-14 | 2014-02-12 | Baylor Res Inst | VACCINES TREATED ON LANGERHANS CELLS |
| BR112012028522A2 (pt) * | 2010-05-07 | 2016-07-19 | Baylor Res Inst | sensibilização cruzada mediada por imunorreceptores de células dendríticas (dcir) de células t humanas cd8+ |
| WO2012009705A1 (en) | 2010-07-15 | 2012-01-19 | Zyngenia, Inc. | Ang-2 binding complexes and uses thereof |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| EP2603520A4 (en) | 2010-08-10 | 2014-02-19 | Ecole Polytech | ERYTHROCYTE BINDING THERAPEUTICS |
| US20120128710A1 (en) * | 2010-11-02 | 2012-05-24 | Baylor Research Institute | Enhancement of Pathogen-Specific Memory Th17 Cell Responses |
| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
| US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
| EP2646468B1 (en) | 2010-12-01 | 2018-07-25 | AlderBio Holdings LLC | Anti-ngf compositions and use thereof |
| US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
| US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| US9623117B2 (en) * | 2011-04-04 | 2017-04-18 | Wisconsin Alumni Research Foundation | Method for selective targeting and entry of bacterial toxins to cells |
| EP2714738B1 (en) | 2011-05-24 | 2018-10-10 | Zyngenia, Inc. | Multivalent and monovalent multispecific complexes and their uses |
| CN102850458B (zh) * | 2011-06-28 | 2014-10-01 | 华博生物医药技术(上海)有限公司 | 新型重组双功能融合蛋白及其制法和用途 |
| AR088428A1 (es) * | 2011-08-25 | 2014-06-11 | Baylor Res Inst | Ensayo multiplexado basado en esferas autoensambladas para anticuerpos especificos de antigenos |
| WO2013033104A1 (en) * | 2011-08-29 | 2013-03-07 | Baylor Research Institute | CONTROLLING ALLERGY AND ASTHMA BY ACTIVATING HUMAN DCs VIA DECTIN-1 OR DECTIN-1 AND TOLL-LIKE RECEPTOR 2 (TLR2) |
| MX354902B (es) * | 2011-11-23 | 2018-03-23 | Bioven 3 Ltd | Proteínas recombinantes y sus usos terapéuticos. |
| CA2875783C (en) * | 2012-06-06 | 2018-12-11 | Zoetis Llc | Caninized anti-ngf antibodies and methods thereof |
| WO2014031984A1 (en) * | 2012-08-24 | 2014-02-27 | Baylor Research Institute | Immunological detection methods and compositions |
| CN103044552B (zh) * | 2012-12-11 | 2019-01-29 | 中国医学科学院病原生物学研究所 | 人源化的抗树突状细胞表面dec-205分子的单克隆抗体 |
| US10150800B2 (en) | 2013-03-15 | 2018-12-11 | Zyngenia, Inc. | EGFR-binding modular recognition domains |
| CN103409451A (zh) * | 2013-06-28 | 2013-11-27 | 扬州维克斯生物科技有限公司 | 一种向树突状细胞dc靶向加载肿瘤抗原肽的方法 |
| CN105555303A (zh) | 2013-06-28 | 2016-05-04 | 贝勒研究院 | 用于多发性硬化症的树突细胞asgpr靶向免疫治疗剂 |
| CN120939216A (zh) | 2014-01-13 | 2025-11-14 | 贝勒研究院 | 抗hpv和hpv相关的疾病的新疫苗 |
| CN112851769A (zh) | 2014-01-27 | 2021-05-28 | 分子模板公司 | 用于哺乳动物中的去免疫化志贺毒素a亚基效应子多肽 |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| SG11201606761RA (en) | 2014-02-21 | 2016-09-29 | Ecole Polytecnique Federale De Lausanne Epfl Epfl Tto | Glycotargeting therapeutics |
| WO2015175957A1 (en) | 2014-05-16 | 2015-11-19 | Baylor Research Institute | Methods and compositions for treating autoimmune and inflammatory conditions |
| EP3253799B1 (en) * | 2015-02-05 | 2020-12-02 | Molecular Templates, Inc. | Multivalent cd20-binding molecules comprising shiga toxin a subunit effector regions and enriched compositions thereof |
| WO2018106895A1 (en) | 2016-12-07 | 2018-06-14 | Molecular Templates, Inc. | Shiga toxin a subunit effector polypeptides, shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugation |
| WO2018232176A1 (en) | 2017-06-16 | 2018-12-20 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
| EP3424538A1 (en) * | 2017-07-06 | 2019-01-09 | Centre National De La Recherche Scientifique | Bioconjugates with a controlled degree of conjugation, their process of preparation, and the reagents for their preparation |
| US10610585B2 (en) | 2017-09-26 | 2020-04-07 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and compositions for treating and preventing HIV |
| EP3790577A4 (en) | 2018-05-09 | 2022-04-27 | The University of Chicago | COMPOSITIONS AND METHODS RELATED TO IMMUNTOLERANCE |
| US20230053449A1 (en) | 2018-10-31 | 2023-02-23 | Novartis Ag | Dc-sign antibody drug conjugates |
| IL263409B2 (en) | 2018-12-02 | 2023-06-01 | Linet Spol Sro | Detection of tiny movement in the human body |
| WO2020193718A1 (en) | 2019-03-27 | 2020-10-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Recombinant proteins with cd40 activating properties |
| CN110790836A (zh) * | 2019-11-22 | 2020-02-14 | 郑州安图生物工程股份有限公司 | 一种人抑制素b的单克隆抗体及其应用和试剂盒 |
| US20230183366A1 (en) | 2020-05-13 | 2023-06-15 | Inserm (Institut National De La Santé Et De La Recherch Médicale) | Recombinant proteins with ox40 activating properties |
| MX2022014943A (es) | 2020-05-26 | 2023-03-08 | Inst Nat Sante Rech Med | Polipéptidos de coronavirus 2 causante del síndrome respiratorio agudo severo (sars-cov-2) y usos de los mismos para propositos de vacuna. |
| MX2023005570A (es) | 2020-11-12 | 2023-05-29 | Inst Nat Sante Rech Med | Anticuerpos conjugados o fusionados al dominio de union del receptor de la proteina de la espicula de sars-cov-2 y usos de los mismos con fines de vacunacion. |
| EP4267176A1 (en) | 2020-12-23 | 2023-11-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Chlamydia vaccine based on targeting momp vs4 antigen to antigen presenting cells |
| US20240124532A1 (en) | 2021-01-29 | 2024-04-18 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Chlamydia trachomatis antigenic polypeptides and uses thereof for vaccine purposes |
| WO2023088968A1 (en) | 2021-11-17 | 2023-05-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Universal sarbecovirus vaccines |
| WO2024074571A1 (en) | 2022-10-05 | 2024-04-11 | Institut National de la Santé et de la Recherche Médicale | Dc-targeting vaccine against nipah virus infection |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| US3949064A (en) * | 1973-10-26 | 1976-04-06 | Baxter Laboratories, Inc. | Method of detecting antigens or antibodies |
| US4174384A (en) | 1975-06-30 | 1979-11-13 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4554101A (en) * | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US20040258688A1 (en) * | 1995-01-31 | 2004-12-23 | Daniel Hawiger | Enhanced antigen delivery and modulation of the immune response therefrom |
| AU726108B2 (en) | 1995-10-17 | 2000-11-02 | Genencor International, Inc. | Enzymatic array and process of making same |
| FR2748479A1 (fr) * | 1996-05-10 | 1997-11-14 | Pasteur Institut | Polypeptide comportant un nouveau domaine cohesine de type ii, composition enzymatique en comportant et fragments d'adn codant pour ces polypeptides |
| US6541011B2 (en) | 1998-02-11 | 2003-04-01 | Maxygen, Inc. | Antigen library immunization |
| JP2000157282A (ja) * | 1998-11-30 | 2000-06-13 | Toyota Central Res & Dev Lab Inc | 酵素配列複合体及び固定化酵素配列複合体とそれらの製造方法、担体分子及び酵素 |
| EP1165813A2 (en) * | 1999-03-24 | 2002-01-02 | The Board Of Regents, The University Of Texas System | Linear and circular expression elements |
| EP1046651A1 (en) * | 1999-04-19 | 2000-10-25 | Koninklijke Universiteit Nijmegen | Composition and method for modulating dendritic cell-T interaction |
| US7560534B2 (en) * | 2000-05-08 | 2009-07-14 | Celldex Research Corporation | Molecular conjugates comprising human monoclonal antibodies to dendritic cells |
| CA2408547A1 (en) * | 2000-05-11 | 2001-11-15 | Altarex Corp. | Therapeutic method and composition utilizing antigen-antibody complexation and presentation by dendritic cells |
| AU2002332598A1 (en) * | 2001-08-22 | 2003-03-10 | Shengfeng Li | Compositions and methods for generating antigen-binding units |
| US20050106700A1 (en) * | 2001-10-11 | 2005-05-19 | Tsuyoshi Nomura | Method of purifying recombinant fused protein and method of producing protein using the same |
| JP2004236504A (ja) * | 2003-02-03 | 2004-08-26 | Toyota Central Res & Dev Lab Inc | 酵素配列複合体及び固定化酵素配列複合体とそれらの製造方法、担体分子及び酵素 |
| US20050064509A1 (en) * | 2003-09-23 | 2005-03-24 | The Regents Of The University Of California | Use of templated self assembly to create novel multifunctional species |
| WO2005058244A2 (en) * | 2003-12-15 | 2005-06-30 | Alexion Pharmaceuticals, Inc. | Novel anti-dc-sign antibodies |
| CA2604032C (en) * | 2005-04-06 | 2017-08-22 | Ibc Pharmaceuticals, Inc. | Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses |
| TWI422594B (zh) * | 2007-02-02 | 2014-01-11 | Baylor Res Inst | 經由樹狀細胞去唾液酸糖蛋白受體(dc-asgpr)接合抗原呈現細胞之藥劑 |
| CN101657464A (zh) * | 2007-02-02 | 2010-02-24 | 贝勒研究院 | 与靶向人源化单克隆抗体复合的多变量抗原 |
| KR20090114430A (ko) * | 2007-02-02 | 2009-11-03 | 베일러 리서치 인스티튜트 | 항원-제시 세포 상에서 발현된 dcir에 대한 항원 표적화에 기초한 백신 |
-
2008
- 2008-01-31 CN CN200880010934A patent/CN101657464A/zh active Pending
- 2008-01-31 MX MX2009008143A patent/MX2009008143A/es active IP Right Grant
- 2008-01-31 KR KR1020097018149A patent/KR20090114425A/ko not_active Ceased
- 2008-01-31 ES ES08728767.8T patent/ES2536900T3/es active Active
- 2008-01-31 CA CA2715042A patent/CA2715042C/en active Active
- 2008-01-31 NZ NZ592859A patent/NZ592859A/xx not_active IP Right Cessation
- 2008-01-31 DK DK08728767T patent/DK2114985T3/en active
- 2008-01-31 US US12/024,036 patent/US7786267B2/en active Active
- 2008-01-31 BR BRPI0807344-9A2A patent/BRPI0807344A2/pt not_active IP Right Cessation
- 2008-01-31 WO PCT/US2008/052714 patent/WO2008097817A2/en not_active Ceased
- 2008-01-31 EP EP13178012.4A patent/EP2684889A3/en not_active Withdrawn
- 2008-01-31 AU AU2008214077A patent/AU2008214077B2/en not_active Ceased
- 2008-01-31 NZ NZ578657A patent/NZ578657A/en not_active IP Right Cessation
- 2008-01-31 JP JP2009548460A patent/JP5543785B2/ja not_active Expired - Fee Related
- 2008-01-31 EP EP08728767.8A patent/EP2114985B1/en active Active
- 2008-02-01 TW TW097104117A patent/TW200846371A/zh unknown
-
2009
- 2009-07-27 IL IL200092A patent/IL200092A0/en unknown
- 2009-08-04 ZA ZA200905447A patent/ZA200905447B/xx unknown
-
2010
- 2010-06-21 US US12/819,618 patent/US20100330115A1/en not_active Abandoned
-
2015
- 2015-10-19 US US14/887,151 patent/US20160031988A1/en not_active Abandoned
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