JP2010516386A - 脈管内リードの安定性のための螺旋体構成 - Google Patents
脈管内リードの安定性のための螺旋体構成 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/056—Transvascular endocardial electrode systems
- A61N1/057—Anchoring means; Means for fixing the head inside the heart
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
- A61N1/0558—Anchoring or fixation means therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36114—Cardiac control, e.g. by vagal stimulation
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Abstract
Description
図7A〜図7Bにおいて最もよく見えるように、リード6の先端部分50は、螺旋体64を形成する1つ以上の螺旋状巻回部を備える。螺旋体64は、時計回り方向または反時計回り方向のいずれに巻回されてもよい。巻回数は、1/2周〜複数周に及び得る。そのピッチは、螺旋体上の2点間の距離として説明することができる。ピッチは、螺旋体64に沿って、0センチメートル(投げ縄形態)〜5cmの範囲で変化してもよいし、または一定のままであってもよい。さらに、螺旋体64は所定の有効外径を有する。螺旋体64の有効外径は、該螺旋体が展開される管の内径よりわずかに大きくなるように選択される。本発明の一実施形態によれば、螺旋体64の有効外径は5mm〜約50mmの範囲である。本発明の別の実施形態によれば、螺旋体64の有効外径は約10mm〜約35mmの範囲である。さらに、螺旋体64は様々な断面形状をとることができる。一実施形態によれば、螺旋体64は円形の断面形状を有する。円形の断面形状は、リードが静脈内で回転する場合に螺旋体64が特定の向きに指向しやすくならないように、配向の偏りを無くすことを可能にする。別の実施形態によれば、螺旋体64は楕円形の断面形状を有する。螺旋体64の外形寸法、径および断面形状は、リード6の先端部分50が展開されるべき管の大きさ、径および形状に応じて選択することができる。螺旋体64の全長は、本発明の一実施形態によれば、患者の解剖学的構造の解剖学的要求に応じて、約30mm〜約200mmの範囲となる。より詳細には、螺旋体64の全長は、約40mm〜約80mmの範囲である。
Claims (16)
- 神経を刺激するための医療用電気リードであって、前記リードは刺激されるべき神経に隣接した管内の刺激部位に送達されるように適合しており、前記リードは、
パルス発生器に接続されるように構成された基端と、
折り畳み形態と、前記リードを前記刺激部位において固定して安定させるための拡張形態との間を移行するように構成された先端部分を備えたリード本体と、前記先端部分は、第1螺旋体、第2螺旋体、および第1螺旋体と第2螺旋体との間に位置する略直線状の部分とを備え、両螺旋体は、所定の有効外径を有し、少なくとも1つの管壁と摩擦係合するように構成されていることと、
前記先端部分に位置し、かつ刺激されるべき神経に電気パルスを経管的に伝えるように構成された1つ以上の電極と、前記先端部分が拡張すると、少なくとも1つの電極が、刺激されるべき神経にごく接近して配置されることと
を備える医療用電気リード。 - 前記管は、内頚静脈、上大静脈および腕頭静脈のうちから選択され、前記神経は迷走神経である、請求項1に記載の医療用電気リード。
- 前記電極と前記迷走神経との間の距離は2mm未満である、請求項2に記載の医療用電気リード。
- 前記螺旋体の所定外径は、前記先端部分が展開される管の内径よりも約5%〜約50%大きい範囲となる、請求項1に記載の医療用電気リード。
- 前記第1螺旋体は第1方向に巻回され、前記第2螺旋体は逆方向である第2方向に巻回される、請求項1に記載の医療用電気リード。
- 少なくとも2つの電極が、刺激されるべき神経と平行に整列する、請求項1に記載の医療用電気リード。
- 前記先端部分はニチノールおよびMP35Nのうちから選択される超弾性材料を含有する、請求項1に記載の医療用電気リード。
- 神経を刺激するための医療用電気リードであって、前記リードは、刺激されるべき神経に隣接した管内の刺激部位に送達されるように構成されており、前記リードは、
パルス発生器に接続されるように構成された基端と、
折り畳み形態からリードを刺激部位において固定して安定させるための拡張形態に移行するように構成される先端部分を備えたリード本体と、前記先端部分は、所定の有効外径を有する少なくとも1つの螺旋体を備え、前記螺旋体の所定の有効外径は、前記リードの先端部分が展開される管の内径よりもわずかに大きく、前記螺旋体は、前記先端部分が拡張形態にあるときに、少なくとも1つの管壁と摩擦係合するように構成されることと、
前記先端部分に位置し、かつ刺激されるべき神経に電気パルスを経管的に伝えるように構成された1つ以上の電極と、前記先端部分が拡張すると、少なくとも1つの電極が、刺激されるべき神経にごく接近して配置されることと
を備える医療用電気リード。 - 前記管は、内頚静脈、上大静脈および腕頭静脈のうちから選択され、前記神経は迷走神経である、請求項8に記載の医療用電気リード。
- 前記1つ以上の電極と前記迷走神経との間の距離は2mm未満である、請求項9に記載の医療用電気リード。
- 前記少なくとも1つの螺旋体の所定外径は、前記先端部分が展開される管の内径よりも約5%〜約50%大きい範囲にある、請求項8に記載の医療用電気リード。
- 前記先端部分は、2つの螺旋体と、それらの2つの螺旋体の間に位置する略直線状の部分とを備え、前記略直線状の部分は、刺激されるべき神経と平行に延びるように構成される、請求項8に記載の医療用電気リード。
- 前記略直線状の部分の上に位置する少なくとも1つの電極をさらに備える、請求項12に記載の医療用電気リード。
- 前記第1螺旋体は第1方向に巻回され、前記第2螺旋体は逆方向の第2方向に巻回される、請求項12に記載の医療用電気リード。
- 前記先端部分は刺激されるべき神経と平行に整列した1つ以上の電極を備える、請求項8に記載の医療用電気リード。
- 前記先端部分はニチノールおよびMP35Nのうちから選択される超弾性材料を含有する、請求項8に記載の医療用電気リード。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US11/668,926 US8244378B2 (en) | 2007-01-30 | 2007-01-30 | Spiral configurations for intravascular lead stability |
PCT/US2007/086127 WO2008094349A1 (en) | 2007-01-30 | 2007-11-30 | Spiral configurations for intravascular lead stability |
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JP2010516386A true JP2010516386A (ja) | 2010-05-20 |
JP2010516386A5 JP2010516386A5 (ja) | 2010-12-24 |
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US (1) | US8244378B2 (ja) |
EP (1) | EP2125106B1 (ja) |
JP (1) | JP2010516386A (ja) |
CN (1) | CN101594907A (ja) |
AU (1) | AU2007345606B2 (ja) |
WO (1) | WO2008094349A1 (ja) |
Cited By (3)
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JP2013056150A (ja) * | 2011-08-18 | 2013-03-28 | Sorin Crm Sas | 冠状静脈網に植込み可能な左心腔用のマルチエリアペーシングリード |
WO2013047015A1 (ja) * | 2011-09-28 | 2013-04-04 | テルモ株式会社 | リード固定具及び医療用装置 |
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- 2007-11-30 WO PCT/US2007/086127 patent/WO2008094349A1/en active Application Filing
- 2007-11-30 AU AU2007345606A patent/AU2007345606B2/en not_active Ceased
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JP2013506494A (ja) * | 2009-09-30 | 2013-02-28 | レスピカーディア, インコーポレイテッド | 事前成形バイアスを有する医療リード線 |
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WO2013047015A1 (ja) * | 2011-09-28 | 2013-04-04 | テルモ株式会社 | リード固定具及び医療用装置 |
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WO2008094349A1 (en) | 2008-08-07 |
US20080183259A1 (en) | 2008-07-31 |
CN101594907A (zh) | 2009-12-02 |
AU2007345606B2 (en) | 2011-12-15 |
AU2007345606A1 (en) | 2008-08-07 |
EP2125106B1 (en) | 2013-06-12 |
US8244378B2 (en) | 2012-08-14 |
EP2125106A1 (en) | 2009-12-02 |
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