JP2010513386A5 - - Google Patents
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- Publication number
- JP2010513386A5 JP2010513386A5 JP2009542018A JP2009542018A JP2010513386A5 JP 2010513386 A5 JP2010513386 A5 JP 2010513386A5 JP 2009542018 A JP2009542018 A JP 2009542018A JP 2009542018 A JP2009542018 A JP 2009542018A JP 2010513386 A5 JP2010513386 A5 JP 2010513386A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- hydrogen
- alkoxy
- halogen
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- PIDUCSIKOLLJAM-UHFFFAOYSA-N CCOC(Cc1c(C)[o]c2c1cc(CN(C)C)cc2)=O Chemical compound CCOC(Cc1c(C)[o]c2c1cc(CN(C)C)cc2)=O PIDUCSIKOLLJAM-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06126534 | 2006-12-19 | ||
| PCT/EP2007/064010 WO2008074752A2 (en) | 2006-12-19 | 2007-12-14 | Indolylmaleimide derivatives as kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010513386A JP2010513386A (ja) | 2010-04-30 |
| JP2010513386A5 true JP2010513386A5 (enExample) | 2011-02-03 |
Family
ID=37989162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009542018A Pending JP2010513386A (ja) | 2006-12-19 | 2007-12-14 | キナーゼ阻害剤としてのインドリルマレイミド誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8193236B2 (enExample) |
| EP (1) | EP2094689B1 (enExample) |
| JP (1) | JP2010513386A (enExample) |
| KR (1) | KR20090100363A (enExample) |
| CN (1) | CN101558062A (enExample) |
| AU (1) | AU2007336338A1 (enExample) |
| BR (1) | BRPI0720388A2 (enExample) |
| CA (1) | CA2671525A1 (enExample) |
| ES (1) | ES2410955T3 (enExample) |
| MX (1) | MX2009006533A (enExample) |
| WO (1) | WO2008074752A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007336338A1 (en) | 2006-12-19 | 2008-06-26 | Novartis Ag | Indolylmaleimide derivatives as kinase inhibitors |
| WO2010144780A1 (en) * | 2009-06-12 | 2010-12-16 | University Of Kansas | Compositions and methods for establishing and maintaining stem cells in an undifferentiated state |
| CN101973993A (zh) * | 2010-11-05 | 2011-02-16 | 天津药物研究院 | 一种制备2-[咪唑并(1,2-a)吡啶-3-基]乙酸的方法 |
| GB201111427D0 (en) * | 2011-07-05 | 2011-08-17 | Amakem Nv | Novel bisindolylmaleimides, pan-pkc inhibitors |
| CN103130790B (zh) * | 2013-03-15 | 2015-10-28 | 浙江工业大学 | 一种3-苯并异噁唑-4-吲哚马来酰亚胺衍生物及其用途 |
| CN103965093A (zh) * | 2014-04-04 | 2014-08-06 | 华南理工大学 | 2-全氟烷基吲哚类化合物及其制备方法和应用 |
| EP3865480B1 (en) | 2014-04-29 | 2025-11-05 | FMC Corporation | Hydrazine derivatives |
| CN104693198B (zh) * | 2014-12-13 | 2017-03-08 | 浙江工业大学 | 3‑(1,2,4‑三氮唑并[4,3‑a]吡啶‑3‑基)‑4‑(1H‑吲哚‑3‑基)马来酰亚胺类衍生物及其制备方法和应用 |
| RU2764746C2 (ru) | 2015-10-28 | 2022-01-20 | Фмк Корпорейшн | Новые пиридазиноновые гербициды |
| JP2022520671A (ja) | 2019-02-08 | 2022-03-31 | フリークエンシー・セラピューティクス・インコーポレイテッド | 耳障害を治療するためのバルプロ酸化合物及びｗｎｔ作動薬 |
| TW202126617A (zh) | 2019-09-20 | 2021-07-16 | 美商富曼西公司 | 間二醯胺類殺蟲劑 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5491242A (en) * | 1994-06-22 | 1996-02-13 | Eli Lilly And Company | Protein kinase C inhibitors |
| US5821072A (en) * | 1996-02-20 | 1998-10-13 | Sloan-Kettering Institute For Cancer Research | Combinations of PKC inhibitors and therapaeutic agents for treating cancers |
| PE91598A1 (es) * | 1996-07-29 | 1998-12-24 | Hoffmann La Roche | Pirroles sustituidos |
| PE91698A1 (es) * | 1996-07-29 | 1998-12-24 | Hoffmann La Roche | Pirroles sustituidos |
| WO1999042100A1 (en) * | 1998-02-23 | 1999-08-26 | Sagami Chemical Research Center | Cell death inhibitors |
| EP1242420A2 (en) * | 1999-12-16 | 2002-09-25 | Eli Lilly And Company | Agents and methods for the treatment of proliferative diseases |
| PT1337527E (pt) * | 2000-11-07 | 2009-12-10 | Novartis Ag | Derivados de indolilmaleimida como inibidores da proteína quinase c |
| AU2002227371B2 (en) * | 2000-12-08 | 2007-05-10 | Ortho-Mcneil Pharmaceutical, Inc. | Macroheterocylic compounds useful as kinase inhibitors |
| KR20040091113A (ko) | 2002-03-08 | 2004-10-27 | 일라이 릴리 앤드 캄파니 | 피롤-2,5-디온 유도체 및 ｇｓｋ-3 억제제로서 그의 용도 |
| PE20040079A1 (es) | 2002-04-03 | 2004-04-19 | Novartis Ag | Derivados de indolilmaleimida |
| WO2003103663A2 (en) * | 2002-06-05 | 2003-12-18 | Janssen Pharmaceutica N.V. | Substituted pyrrolines as kinase inhibitors |
| GB0303319D0 (en) | 2003-02-13 | 2003-03-19 | Novartis Ag | Organic compounds |
| CN1832940A (zh) * | 2003-06-13 | 2006-09-13 | 詹森药业有限公司 | 用作激酶抑制剂的取代的吲唑基(吲哚基)马来酰亚胺衍生物 |
| SI1846406T1 (sl) * | 2005-02-09 | 2011-02-28 | Arqule Inc | Maleimidni derivati, farmacevtski sestavki in postopki za zdravljenje raka |
| US7781438B2 (en) | 2005-07-11 | 2010-08-24 | Novartis Ag | Indolylmaleimide derivatives |
| AU2007336338A1 (en) | 2006-12-19 | 2008-06-26 | Novartis Ag | Indolylmaleimide derivatives as kinase inhibitors |
-
2007
- 2007-12-14 AU AU2007336338A patent/AU2007336338A1/en not_active Abandoned
- 2007-12-14 KR KR1020097012645A patent/KR20090100363A/ko not_active Withdrawn
- 2007-12-14 WO PCT/EP2007/064010 patent/WO2008074752A2/en not_active Ceased
- 2007-12-14 CA CA002671525A patent/CA2671525A1/en not_active Abandoned
- 2007-12-14 BR BRPI0720388-8A patent/BRPI0720388A2/pt not_active Application Discontinuation
- 2007-12-14 ES ES07857644T patent/ES2410955T3/es active Active
- 2007-12-14 MX MX2009006533A patent/MX2009006533A/es not_active Application Discontinuation
- 2007-12-14 EP EP07857644A patent/EP2094689B1/en not_active Not-in-force
- 2007-12-14 US US12/520,025 patent/US8193236B2/en not_active Expired - Fee Related
- 2007-12-14 JP JP2009542018A patent/JP2010513386A/ja active Pending
- 2007-12-14 CN CNA2007800465026A patent/CN101558062A/zh active Pending
-
2012
- 2012-05-07 US US13/465,212 patent/US8742132B2/en not_active Expired - Fee Related
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