JP2010512414A - 肺高血圧を処置するための組成物 - Google Patents
肺高血圧を処置するための組成物 Download PDFInfo
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- JP2010512414A JP2010512414A JP2009541511A JP2009541511A JP2010512414A JP 2010512414 A JP2010512414 A JP 2010512414A JP 2009541511 A JP2009541511 A JP 2009541511A JP 2009541511 A JP2009541511 A JP 2009541511A JP 2010512414 A JP2010512414 A JP 2010512414A
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2014506870A (ja) * | 2010-10-15 | 2014-03-20 | ギリアード サイエンシーズ， インコーポレイテッド | 肺高血圧症を処置するための組成物および方法 |
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| ES2544724T3 (es) | 2006-12-12 | 2015-09-03 | Gilead Sciences, Inc. | Composición para tratar una hipertensión pulmonar |
| CA2693400A1 (en) * | 2007-07-11 | 2009-01-15 | Lexicon Pharmaceuticals, Inc. | Methods and compositions for treating pulmonary hypertension and related diseases and disorders |
| CA2695259C (en) | 2007-07-31 | 2016-05-24 | Gilead Colorado, Inc. | Metabolites and derivatives of ambrisentan |
| WO2010062640A1 (en) * | 2008-10-28 | 2010-06-03 | Gilead Colorado, Inc. | Methods for treating idiopathic pulmonary fibrosis and associated complications |
| KR20130088834A (ko) * | 2010-06-30 | 2013-08-08 | 길리애드 사이언시즈, 인코포레이티드 | 폐 고혈압의 치료를 위한 ａ２ｂ 아데노신 수용체 길항제의 용도 |
| EP2741777B1 (en) * | 2011-08-12 | 2017-01-18 | INSERM - Institut National de la Santé et de la Recherche Médicale | Methods and pharmaceutical compositions for treatment of pulmonary hypertension |
| US20130225595A1 (en) * | 2012-02-29 | 2013-08-29 | Gilead Sciences, Inc. | Method for treating pulmonary arterial hypertension in a patient not having idiopathic pulmonary fibrosis |
| US20130224306A1 (en) * | 2012-02-29 | 2013-08-29 | Gilead Sciences, Inc. | Method for treating a pulmonary hypertension condition without companion diagnosis |
| WO2014003678A1 (en) * | 2012-06-28 | 2014-01-03 | Xspray Microparticles Ab | Pharmaceutical compositions comprising ambrisentan and solid dispersion particles containing tadalafil |
| WO2015193889A1 (en) * | 2014-06-18 | 2015-12-23 | Sonivie Ltd. | Method for treating secondary pulmonary hypertension |
| US10576083B2 (en) * | 2015-08-13 | 2020-03-03 | Cipla (UK) Limited | Method of treating pulmonary arterial hypertension |
| AU2017296040C1 (en) | 2016-07-15 | 2023-06-22 | Acceleron Pharma Inc. | Compositions and methods for treating pulmonary hypertension |
| SG11202000893QA (en) * | 2017-08-30 | 2020-02-27 | Bellerophon Pulse Tech Llc | Use of inhaled nitric oxide for the treatment of pulmonary hypertension associated with lung disease |
| EA202091286A1 (ru) * | 2017-12-28 | 2020-11-05 | Беллерофон Пульс Текнолоджис Ллс | Применение вдыхаемого оксида азота (ii) и кислорода для лечения легочной гипертензии |
| EP3965767A1 (en) * | 2019-05-06 | 2022-03-16 | Actelion Pharmaceuticals Ltd | Methods for treating sarcoidosis-associated pulmonary hypertension |
| US11969424B2 (en) | 2019-12-16 | 2024-04-30 | Tenax Therapeutics, Inc. | Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (PH-HFpEF) |
| RU2729033C1 (ru) * | 2020-02-03 | 2020-08-03 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр кардиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ кардиологии" Минздрава России) | Способ прогнозирования эффективности длительной специфической терапии у пациентов с идиопатической легочной гипертензией и неоперабельной хронической тромбоэмболической легочной гипертензией |
| EP4142731A1 (en) * | 2020-04-28 | 2023-03-08 | Noorik Biopharmaceuticals AG | Treatment of pulmonary complications of coronavirus infections |
| EP3906928A1 (en) * | 2020-05-06 | 2021-11-10 | Noorik Biopharmaceuticals AG | Treatment of pulmonary complications of coronavirus |
| CN114324900A (zh) * | 2021-12-03 | 2022-04-12 | 上海市肺科医院 | 一种促卵泡激素的应用 |
| US20250064799A1 (en) | 2021-12-31 | 2025-02-27 | Tenax Therapeutics, Inc. | Oral formulations of levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction |
| AU2024207876A1 (en) * | 2023-01-09 | 2025-07-31 | Scpharmaceuticals Inc. | Methods of treatment using loop diuretics |
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| US4902514A (en) | 1988-07-21 | 1990-02-20 | Alza Corporation | Dosage form for administering nilvadipine for treating cardiovascular symptoms |
| US5250534A (en) | 1990-06-20 | 1993-10-05 | Pfizer Inc. | Pyrazolopyrimidinone antianginal agents |
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| SI2013208T1 (sl) * | 2006-04-21 | 2011-09-30 | Pfizer Prod Inc | Piridin(3,4-b)pirazinoni |
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| ES2544724T3 (es) * | 2006-12-12 | 2015-09-03 | Gilead Sciences, Inc. | Composición para tratar una hipertensión pulmonar |
| CA2695259C (en) | 2007-07-31 | 2016-05-24 | Gilead Colorado, Inc. | Metabolites and derivatives of ambrisentan |
| WO2010062640A1 (en) | 2008-10-28 | 2010-06-03 | Gilead Colorado, Inc. | Methods for treating idiopathic pulmonary fibrosis and associated complications |
| ES2627944T3 (es) | 2010-10-15 | 2017-08-01 | Gilead Sciences, Inc. | Composiciones y métodos de tratamiento de hipertensión pulmonar |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014506870A (ja) * | 2010-10-15 | 2014-03-20 | ギリアード サイエンシーズ， インコーポレイテッド | 肺高血圧症を処置するための組成物および方法 |
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| US20150224100A1 (en) | 2015-08-13 |
| US8377933B2 (en) | 2013-02-19 |
| PL2101777T3 (pl) | 2015-10-30 |
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| CY2016017I1 (el) | 2016-10-05 |
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| US9474752B2 (en) | 2016-10-25 |
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| US9504685B2 (en) | 2016-11-29 |
| HUE025355T2 (en) | 2016-02-29 |
| EP2952193A1 (en) | 2015-12-09 |
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| HK1218393A1 (en) | 2017-02-17 |
| CA2669536A1 (en) | 2008-06-19 |
| US20100152217A1 (en) | 2010-06-17 |
| AU2007333115A1 (en) | 2008-06-19 |
| SI2101777T1 (sl) | 2015-08-31 |
| US20170136016A1 (en) | 2017-05-18 |
| PT2101777E (pt) | 2015-09-18 |
| DK2101777T3 (en) | 2015-08-17 |
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