JP2010508015A5 - - Google Patents
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- Publication number
- JP2010508015A5 JP2010508015A5 JP2009533756A JP2009533756A JP2010508015A5 JP 2010508015 A5 JP2010508015 A5 JP 2010508015A5 JP 2009533756 A JP2009533756 A JP 2009533756A JP 2009533756 A JP2009533756 A JP 2009533756A JP 2010508015 A5 JP2010508015 A5 JP 2010508015A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- reporter molecule
- handle
- alkyne
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85557406P | 2006-10-31 | 2006-10-31 | |
| US60/855,574 | 2006-10-31 | ||
| PCT/EP2007/009474 WO2008052775A2 (en) | 2006-10-31 | 2007-10-31 | Click chemistry for the production of reporter molecules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010508015A JP2010508015A (ja) | 2010-03-18 |
| JP2010508015A5 true JP2010508015A5 (enExample) | 2010-12-16 |
| JP5646172B2 JP5646172B2 (ja) | 2014-12-24 |
Family
ID=39344631
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009533756A Expired - Fee Related JP5646172B2 (ja) | 2006-10-31 | 2007-10-31 | リポーター分子の製造のためのクリックケミストリー |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8193335B2 (enExample) |
| EP (1) | EP2089343B1 (enExample) |
| JP (1) | JP5646172B2 (enExample) |
| CN (1) | CN101605743A (enExample) |
| AT (1) | ATE515488T1 (enExample) |
| AU (1) | AU2007315190B2 (enExample) |
| CA (1) | CA2667136A1 (enExample) |
| DK (1) | DK2089343T3 (enExample) |
| ES (1) | ES2369299T3 (enExample) |
| HR (1) | HRP20110554T1 (enExample) |
| PL (1) | PL2089343T3 (enExample) |
| PT (1) | PT2089343E (enExample) |
| SI (1) | SI2089343T1 (enExample) |
| WO (1) | WO2008052775A2 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101335218B1 (ko) | 2005-05-02 | 2013-12-12 | 바스프 에스이 | 분석물의 감응성 검출을 위한 신규한 표지화 전략 |
| CA2607530C (en) * | 2005-05-02 | 2014-07-08 | Basf Aktiengesellschaft | New labelling strategies for the sensitive detection of analytes |
| WO2008052775A2 (en) | 2006-10-31 | 2008-05-08 | Baseclick Gmbh | Click chemistry for the production of reporter molecules |
| EP2129772B1 (en) | 2007-02-27 | 2016-07-27 | Trustees Of Tufts College | Tissue-engineered silk organs |
| DK2211876T3 (en) | 2007-05-29 | 2015-01-12 | Tufts College | PROCESS FOR silk fibroin-GELATION USING sonication |
| US8618297B2 (en) | 2008-07-25 | 2013-12-31 | Basf Se | Azide substituted naphthylene or rylene imide derivatives and their use as reagents in click-reactions |
| WO2010039548A2 (en) | 2008-09-23 | 2010-04-08 | Alnylam Pharmaceuticals, Inc. | Chemical modifications of monomers and oligonucleotides with cycloaddition |
| EP2358897B1 (en) | 2008-11-17 | 2015-02-25 | Headway Technologies, Inc. | Methods and compositions in particle-based detection of target molecules using linking molecules |
| JP5744743B2 (ja) | 2008-11-17 | 2015-07-08 | ヘッドウェイ テクノロジーズ, インク.Headway Technologies, Inc. | 共有結合形成反応ペアを用いた標的分子の粒子ベースの検出における方法および組成物 |
| JP5569768B2 (ja) * | 2008-12-02 | 2014-08-13 | 国立大学法人九州大学 | ヌクレオシド三リン酸誘導体、核酸プローブ、マルチラベル化核酸プローブおよび標的核酸の検出方法 |
| EP2239053A1 (en) | 2009-04-09 | 2010-10-13 | baseclick GmbH | Click chemistry on heterogeneous catalysts |
| US9074302B2 (en) | 2009-09-28 | 2015-07-07 | Trustees Of Tufts College | Methods of making drawn silk fibers |
| AU2011317107B2 (en) | 2010-10-19 | 2016-02-25 | Trustees Of Tufts College | Silk fibroin-based microneedles and methods of making the same |
| CN102010508B (zh) * | 2010-10-19 | 2012-10-03 | 北京大学 | 一种阳离子聚合物及其制备方法和应用 |
| CN103476951B (zh) | 2011-02-16 | 2017-07-28 | 海德威技术公司 | 用于可检测的标记的靶标定位锚定的方法和组合物 |
| WO2012145652A1 (en) | 2011-04-20 | 2012-10-26 | Trustees Of Tufts College | Dynamic silk coatings for implantable devices |
| US9988680B2 (en) | 2011-09-01 | 2018-06-05 | Case Western Reserve University | Non-natural nucleosides as theranostic agents |
| WO2013152619A1 (en) * | 2012-04-12 | 2013-10-17 | The Hong Kong University Of Science And Technology | Thermosetting poly(siloxane-diphenylbutadiyne) with readily tunable glass transition temperature and high thermal stability |
| BR112015000236A2 (pt) | 2012-07-10 | 2017-06-27 | Baseclick Gmbh | moléculas de ácidos nucleicos modificadas por anandamida |
| CA2891966A1 (en) | 2012-12-20 | 2014-06-26 | Sirna Therapeutics, Inc. | Post-synthetic orthogonal amidation plus metal catalyzed azide-alkyne cycloaddition click chemistry on sirna |
| US20160159834A1 (en) * | 2013-04-22 | 2016-06-09 | Northwestern University | Alkyne phosphoramidites and preparation of spherical nucleic acid constructs |
| EP3730929A1 (en) * | 2013-08-19 | 2020-10-28 | University Of Houston | Phosphorescent reporters |
| CN105764491A (zh) | 2013-12-09 | 2016-07-13 | 度瑞公司 | 药物活性剂复合物、聚合物复合物，以及包括其的组合物和方法 |
| HK1244813A1 (zh) * | 2014-11-20 | 2018-08-17 | F. Hoffmann-La Roche Ag | 氰脲酸酯磷醯胺酯及其衍生物，其用途和合成 |
| JP6667179B2 (ja) * | 2015-03-24 | 2020-03-18 | 国立大学法人岐阜大学 | オリゴヌクレオチド誘導体及びそれを用いたオリゴヌクレオチド構築物並びにそれらの製造方法 |
| WO2017218293A1 (en) | 2016-06-16 | 2017-12-21 | Richard Edward Watts | Oligonucleotide directed and recorded combinatorial synthesis of encoded probe molecules |
| WO2018204420A1 (en) | 2017-05-02 | 2018-11-08 | Haystack Sciences Corporation | Molecules for verifying oligonucleotide directed combinatorial synthesis and methods of making and using the same |
| CN109490523A (zh) * | 2018-10-22 | 2019-03-19 | 北京纳晶生物科技有限公司 | 用于标记的纳米材料、核酸探针及核酸与纳米材料偶联的方法 |
| CN112305227A (zh) * | 2019-07-31 | 2021-02-02 | 深圳市帝迈生物技术有限公司 | 自交联蛋白、配体组合物、制备方法、试剂盒及系统 |
| CN111018930A (zh) * | 2019-12-06 | 2020-04-17 | 深圳大学 | Tpe-2’-脱氧核苷、荧光凝胶及其制备方法与应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2209754A (en) | 1987-09-17 | 1989-05-24 | Thomas Lee Mattson | Polyaldehydic polynucleotides in use as probes,their preparation and use |
| JP2681061B2 (ja) * | 1988-06-08 | 1997-11-19 | ロンドン・ダイアグノスティック・インコーポレーテッド | 検出可能なシグナルのセンシタイザー誘導発生を利用したアッセイ |
| US5723289A (en) | 1990-06-11 | 1998-03-03 | Nexstar Pharmaceuticals, Inc. | Parallel selex |
| US5843650A (en) | 1995-05-01 | 1998-12-01 | Segev; David | Nucleic acid detection and amplification by chemical linkage of oligonucleotides |
| EP2256133B1 (en) * | 1997-01-08 | 2016-12-14 | Sigma-Aldrich Co. LLC | Bioconjugation of macromolecules |
| US7427678B2 (en) * | 1998-01-08 | 2008-09-23 | Sigma-Aldrich Co. | Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method |
| US6727356B1 (en) | 1999-12-08 | 2004-04-27 | Epoch Pharmaceuticals, Inc. | Fluorescent quenching detection reagents and methods |
| US7205105B2 (en) * | 1999-12-08 | 2007-04-17 | Epoch Biosciences, Inc. | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis |
| DE10013600A1 (de) * | 2000-03-18 | 2002-01-10 | Aventis Res & Tech Gmbh & Co | Reaktive Monomere für die Oligonucleotid- und Polynucleotidsynthese, modifizierte Oligonucleotide und Polynucleotiden und ein Verfahren zu deren Herstellung |
| WO2003079014A1 (en) * | 2002-03-03 | 2003-09-25 | Activx Biosciences, Inc. | Tethered activity-based probes and uses thereof |
| ATE469135T1 (de) | 2002-05-30 | 2010-06-15 | Scripps Research Inst | Kupferkatalysierte ligierung von aziden und acetylenen |
| WO2004055160A2 (en) * | 2002-12-13 | 2004-07-01 | The Trustees Of Columbia University In The City Of New York | Biomolecular coupling methods using 1,3-dipolar cycloaddition chemistry |
| KR100540509B1 (ko) * | 2004-01-07 | 2006-01-11 | 학교법인 포항공과대학교 | 수화젤레이터로 사용되는 2'-데옥시우리딘 유도체 |
| US7745118B2 (en) * | 2004-04-08 | 2010-06-29 | Roche Nimblegen, Inc. | Comparative genomic resequencing |
| EP1875240A2 (en) | 2005-04-27 | 2008-01-09 | Siemens Medical Solutions USA, Inc. | The preparation of molecular imaging probes using click chemistry |
| CA2607530C (en) * | 2005-05-02 | 2014-07-08 | Basf Aktiengesellschaft | New labelling strategies for the sensitive detection of analytes |
| EP1937850B1 (en) | 2005-10-27 | 2019-05-29 | The President and Fellows of Harvard College | Methods and compositions for labeling nucleic acids |
| WO2008052775A2 (en) | 2006-10-31 | 2008-05-08 | Baseclick Gmbh | Click chemistry for the production of reporter molecules |
-
2007
- 2007-10-31 WO PCT/EP2007/009474 patent/WO2008052775A2/en not_active Ceased
- 2007-10-31 CN CNA2007800405932A patent/CN101605743A/zh active Pending
- 2007-10-31 JP JP2009533756A patent/JP5646172B2/ja not_active Expired - Fee Related
- 2007-10-31 AU AU2007315190A patent/AU2007315190B2/en not_active Ceased
- 2007-10-31 EP EP07819506A patent/EP2089343B1/en active Active
- 2007-10-31 CA CA002667136A patent/CA2667136A1/en not_active Abandoned
- 2007-10-31 HR HR20110554T patent/HRP20110554T1/hr unknown
- 2007-10-31 SI SI200730721T patent/SI2089343T1/sl unknown
- 2007-10-31 AT AT07819506T patent/ATE515488T1/de active
- 2007-10-31 DK DK07819506.2T patent/DK2089343T3/da active
- 2007-10-31 ES ES07819506T patent/ES2369299T3/es active Active
- 2007-10-31 US US12/447,526 patent/US8193335B2/en active Active
- 2007-10-31 PT PT07819506T patent/PT2089343E/pt unknown
- 2007-10-31 PL PL07819506T patent/PL2089343T3/pl unknown
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