JP2010507619A - オキサジアゾール及びチアジアゾール化合物並びにニコチン性アセチルコリン受容体調節物質としてのその使用 - Google Patents
オキサジアゾール及びチアジアゾール化合物並びにニコチン性アセチルコリン受容体調節物質としてのその使用 Download PDFInfo
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- JP2010507619A JP2010507619A JP2009533834A JP2009533834A JP2010507619A JP 2010507619 A JP2010507619 A JP 2010507619A JP 2009533834 A JP2009533834 A JP 2009533834A JP 2009533834 A JP2009533834 A JP 2009533834A JP 2010507619 A JP2010507619 A JP 2010507619A
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- Prior art keywords
- oxadiazol
- phenyl
- pyridine
- pyridin
- benzonitrile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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Applications Claiming Priority (3)
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| US85407806P | 2006-10-25 | 2006-10-25 | |
| DKPA200601380 | 2006-10-25 | ||
| PCT/EP2007/061433 WO2008049864A1 (en) | 2006-10-25 | 2007-10-24 | Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators |
Publications (2)
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| JP2010507619A true JP2010507619A (ja) | 2010-03-11 |
| JP2010507619A5 JP2010507619A5 (cg-RX-API-DMAC7.html) | 2010-08-05 |
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| US (1) | US20100029685A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2079734A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2010507619A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007310897A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2667545A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL197397A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2009003892A (cg-RX-API-DMAC7.html) |
| NO (1) | NO20091977L (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008049864A1 (cg-RX-API-DMAC7.html) |
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|---|---|---|---|---|
| JP2013544792A (ja) * | 2010-10-22 | 2013-12-19 | バイエル・インテレクチユアル・プロパテイー・ゲー・エム・ベー・ハー | 殺害虫剤としての新規ヘテロ環式化合物 |
| JP2019500352A (ja) * | 2015-12-10 | 2019-01-10 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
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| JP5762743B2 (ja) | 2007-08-13 | 2015-08-12 | モンサント テクノロジー エルエルシー | 線虫を制御するための組成物および方法 |
| AU2013203846B2 (en) * | 2007-08-13 | 2016-02-25 | Monsanto Technology Llc | Compositions and methods for controlling nematodes |
| GB0723719D0 (en) * | 2007-12-04 | 2008-01-16 | Glaxo Group Ltd | Compounds |
| GB0723815D0 (en) * | 2007-12-05 | 2008-01-16 | Glaxo Group Ltd | Compounds |
| WO2009149135A1 (en) * | 2008-06-04 | 2009-12-10 | Abbott Laboratories | Bis (hetero ) aryl substituted isoxazoles for use as neuronal nicotinic receptor modulators |
| ES2573149T3 (es) * | 2008-07-17 | 2016-06-06 | Bayer Cropscience Ag | Compuestos heterocíclicos como pesticidas |
| MX2011001844A (es) * | 2008-09-02 | 2011-04-05 | Neurosearch As | Derivados de triazol y su uso como moduladores del receptor de acetilcolina nicotinico. |
| US8017555B2 (en) | 2009-02-10 | 2011-09-13 | Divergence, Inc. | Compositions and methods for controlling nematodes |
| WO2011047129A1 (en) | 2009-10-15 | 2011-04-21 | Southern Research Institute | Treatment of neurodegenerative diseases, causation of memory enhancement, and assay for screening compounds for such |
| WO2011073299A1 (en) | 2009-12-18 | 2011-06-23 | Neurosearch A/S | Pyridinyl oxadiazole compounds and their use as nicotinic acetylcholine receptor modulators |
| RU2012154447A (ru) | 2010-05-12 | 2014-06-20 | Вандербилт Юниверсити | Гетероциклические сульфоновые аллостерические потенциаторы mglur4, композиции и способы лечения неврологических дисфункций |
| US9339035B2 (en) | 2010-09-02 | 2016-05-17 | Monsanto Technology Llc | Compositions and methods for controlling nematode pests |
| EP2967065A4 (en) | 2013-03-15 | 2016-08-24 | Monsanto Technology Llc | N-, C-SUBSTITUTED AZOLE FOR COMBATING NEMATODE PENINS |
| CZ305680B6 (cs) * | 2013-04-04 | 2016-02-03 | Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové | Substituovaný diazol, jeho použití a farmaceutický přípravek ho obsahující |
| US10513110B2 (en) * | 2014-06-13 | 2019-12-24 | Electronics For Imaging, Inc. | Integration of a line-scan camera on a single pass inkjet printer |
| WO2018226622A1 (en) | 2017-06-05 | 2018-12-13 | Ptc Therapeutics, Inc. | Compounds for treating huntington's disease |
| EP3645121B8 (en) | 2017-06-28 | 2025-06-18 | PTC Therapeutics, Inc. | Methods for treating huntington's disease |
| BR112019027717A2 (pt) | 2017-06-28 | 2020-07-28 | Ptc Therapeutics, Inc. | métodos para tratar a doença de huntington |
| CA3094703A1 (en) | 2018-03-27 | 2019-10-03 | Ptc Therapeutics, Inc. | Compounds for treating huntington's disease |
| CN112805280B (zh) | 2018-06-27 | 2024-12-06 | Ptc医疗公司 | 用于治疗亨廷顿氏病的杂芳基化合物 |
| JP7421507B2 (ja) | 2018-06-27 | 2024-01-24 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病を処置するためのヘテロ環式およびヘテロアリール化合物 |
| WO2020005882A1 (en) | 2018-06-27 | 2020-01-02 | Ptc Therapeutics, Inc. | Heteroaryl compounds for treating huntington's disease |
| JP2022547079A (ja) * | 2019-09-05 | 2022-11-10 | トレベナ・インコーポレイテッド | てんかんを治療する方法を使用しててんかんを治療する方法 |
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| CH411906A (de) * | 1960-03-01 | 1966-04-30 | Ciba Geigy | Verfahren zur Herstellung neuer 1,3,4-Thiadiazole |
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| US6699853B2 (en) * | 1997-06-16 | 2004-03-02 | Hoechst Schering Agrevo Gmbh | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides |
| US6660753B2 (en) * | 1999-08-19 | 2003-12-09 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| AR032653A1 (es) * | 2001-02-09 | 2003-11-19 | Telik Inc | Inhibidores heterociclicos del trasportador de glicina 2 composiciones farmaceuticas, uso y metodos. |
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| FR2832712B1 (fr) * | 2001-11-23 | 2004-02-13 | Sanofi Synthelabo | Derives de 4-(oxadiazol-3-yl)-1,4-diazabicyclo[3.2.2]nonane, leur preparation et leur application en therapeutique |
| FR2832713B1 (fr) * | 2001-11-23 | 2004-02-13 | Sanofi Synthelabo | Derives de 4-(1,3,4-thiadiazol-2-yl)-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique |
| BRPI0506890A (pt) * | 2004-02-04 | 2007-07-17 | Neurosearch As | derivado de arila diazabicìclica, composição farmacêutica, uso de um derivado de arila diazabicìclica, e, método de tratamento, prevenção ou alìvio de uma doença, distúrbio ou condição de um corpo de animal vivo |
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| WO2007149395A2 (en) * | 2006-06-20 | 2007-12-27 | Amphora Discovery Corporation | 2,5-substituted oxazole derivatives as protein kinase inhibitors for the treatment of cancer |
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| AU2009256982A1 (en) * | 2008-06-09 | 2009-12-17 | Sanofi-Aventis | Annelated N-heterocyclic sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals |
| US20100249071A1 (en) * | 2009-03-30 | 2010-09-30 | Exelixis, Inc. | Modulators of S1P and Methods of Making And Using |
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-
2007
- 2007-10-24 AU AU2007310897A patent/AU2007310897A1/en not_active Abandoned
- 2007-10-24 MX MX2009003892A patent/MX2009003892A/es not_active Application Discontinuation
- 2007-10-24 EP EP07821796A patent/EP2079734A1/en not_active Withdrawn
- 2007-10-24 JP JP2009533834A patent/JP2010507619A/ja not_active Abandoned
- 2007-10-24 WO PCT/EP2007/061433 patent/WO2008049864A1/en not_active Ceased
- 2007-10-24 CA CA002667545A patent/CA2667545A1/en not_active Abandoned
- 2007-10-24 US US12/447,205 patent/US20100029685A1/en not_active Abandoned
-
2009
- 2009-03-04 IL IL197397A patent/IL197397A0/en unknown
- 2009-05-20 NO NO20091977A patent/NO20091977L/no not_active Application Discontinuation
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013544792A (ja) * | 2010-10-22 | 2013-12-19 | バイエル・インテレクチユアル・プロパテイー・ゲー・エム・ベー・ハー | 殺害虫剤としての新規ヘテロ環式化合物 |
| US9173396B2 (en) | 2010-10-22 | 2015-11-03 | Bayer Intellectual Property Gmbh | Heterocyclic compounds as pesticides |
| JP2019500352A (ja) * | 2015-12-10 | 2019-01-10 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
| JP2021028331A (ja) * | 2015-12-10 | 2021-02-25 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
| JP2021042211A (ja) * | 2015-12-10 | 2021-03-18 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
| JP7025508B2 (ja) | 2015-12-10 | 2022-02-24 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
| JP7053760B2 (ja) | 2015-12-10 | 2022-04-12 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2079734A1 (en) | 2009-07-22 |
| US20100029685A1 (en) | 2010-02-04 |
| NO20091977L (no) | 2009-05-20 |
| MX2009003892A (es) | 2009-04-23 |
| WO2008049864A1 (en) | 2008-05-02 |
| CA2667545A1 (en) | 2008-05-02 |
| AU2007310897A1 (en) | 2008-05-02 |
| IL197397A0 (en) | 2009-12-24 |
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