JP2010506950A5 - - Google Patents
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- Publication number
- JP2010506950A5 JP2010506950A5 JP2009533499A JP2009533499A JP2010506950A5 JP 2010506950 A5 JP2010506950 A5 JP 2010506950A5 JP 2009533499 A JP2009533499 A JP 2009533499A JP 2009533499 A JP2009533499 A JP 2009533499A JP 2010506950 A5 JP2010506950 A5 JP 2010506950A5
- Authority
- JP
- Japan
- Prior art keywords
- hydrogen
- lower alkyl
- independently
- formula
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 125000000217 alkyl group Chemical group 0.000 description 14
- 229910052739 hydrogen Inorganic materials 0.000 description 13
- 239000001257 hydrogen Substances 0.000 description 13
- 125000003545 alkoxy group Chemical group 0.000 description 7
- 229910052736 halogen Inorganic materials 0.000 description 6
- 150000002367 halogens Chemical class 0.000 description 6
- 150000002431 hydrogen Chemical class 0.000 description 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 5
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 125000003003 spiro group Chemical group 0.000 description 3
- 229910052717 sulfur Inorganic materials 0.000 description 3
- 102100007851 DGAT1 Human genes 0.000 description 2
- 125000003368 amide group Chemical group 0.000 description 2
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 description 2
- 101700039623 DGAT1 Proteins 0.000 description 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 125000000753 cycloalkyl group Chemical group 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 108060000942 fbpB Proteins 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000651 prodrug Substances 0.000 description 1
- 229940002612 prodrugs Drugs 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82998006P | 2006-10-18 | 2006-10-18 | |
| US60/829,980 | 2006-10-18 | ||
| US95234107P | 2007-07-27 | 2007-07-27 | |
| US60/952,341 | 2007-07-27 | ||
| PCT/US2007/081607 WO2008048991A2 (en) | 2006-10-18 | 2007-10-17 | Organic compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010506950A JP2010506950A (ja) | 2010-03-04 |
| JP2010506950A5 true JP2010506950A5 (US07794700-20100914-C00152.png) | 2010-11-25 |
| JP5298022B2 JP5298022B2 (ja) | 2013-09-25 |
Family
ID=39276877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009533499A Expired - Fee Related JP5298022B2 (ja) | 2006-10-18 | 2007-10-17 | 有機化合物 |
Country Status (15)
Families Citing this family (46)
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| AU2007266890B2 (en) | 2006-05-30 | 2011-02-17 | Astrazeneca Ab | 1, 3, 4 -oxadiazole derivatives as DGAT1 inhibitors |
| BRPI0821274A2 (pt) | 2007-12-20 | 2017-06-13 | Astrazeneca Ab | composto ou um sal, ou pró-droga farmaceuticamente aceitável do mesmo, uso do mesmo, método para tratar uma doença em um animal de sangue quente, e, composição farmacêutica |
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| AU2013207510A1 (en) | 2012-01-06 | 2014-07-31 | The Regents Of The University Of California | Compositions, methods of use, and methods of treatment |
| BR112015014752B1 (pt) | 2012-12-21 | 2022-07-05 | Plexxikon, Inc | Compostos e seus uso para modulação de cinase |
| US9296754B2 (en) | 2013-03-15 | 2016-03-29 | Novartis Ag | Compounds and compositions for the treatment of parasitic diseases |
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| CA2938311C (en) | 2014-02-03 | 2023-03-07 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ror-gamma |
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| SI3207043T1 (sl) | 2014-10-14 | 2019-04-30 | Vitae Pharmaceuticals, Inc. | Dihidropirolopiridinovi inhibitorji za ROR-gama |
| US9663515B2 (en) | 2014-11-05 | 2017-05-30 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
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| US10301261B2 (en) | 2015-08-05 | 2019-05-28 | Vitae Pharmaceuticals, Llc | Substituted indoles as modulators of ROR-gamma |
| CN108463458B (zh) | 2015-11-20 | 2022-02-01 | 生命医药有限责任公司 | ROR-γ的调节剂 |
| TW202220968A (zh) | 2016-01-29 | 2022-06-01 | 美商維它藥物有限責任公司 | ＲＯＲ－γ調節劑 |
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| WO2018054989A1 (en) * | 2016-09-20 | 2018-03-29 | Centre Leon Berard | Benzoimidazole derivatives as anticancer agents |
| WO2019018975A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF ROR GAMMA |
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| AU2019309894A1 (en) | 2018-07-27 | 2021-01-28 | Biotheryx, Inc. | Bifunctional compounds as CDK modulators |
| CA3110576A1 (en) | 2018-09-18 | 2020-03-26 | Terns, Inc. | Compounds for treating certain leukemias |
| WO2020120576A1 (en) * | 2018-12-11 | 2020-06-18 | Fundació Institut De Recerca Biomèdica (Irb Barcelona) | p38α AUTOPHOSPHORYLATION INHIBITORS |
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| JP2023512116A (ja) * | 2020-01-28 | 2023-03-23 | プロテゴ バイオファーマ， インコーポレイテッド | トランスサイレチンの安定化及びトランスサイレチンの誤った折り畳みの阻害のための化合物、組成物、及び方法 |
| US11897930B2 (en) | 2020-04-28 | 2024-02-13 | Anwita Biosciences, Inc. | Interleukin-2 polypeptides and fusion proteins thereof, and their pharmaceutical compositions and therapeutic applications |
| CN116745267A (zh) * | 2020-12-11 | 2023-09-12 | 跨膜蛋白16A有限公司 | 用于治疗呼吸系统疾病的苯并咪唑衍生物 |
| CA3220039A1 (en) | 2021-06-14 | 2022-12-22 | Jr. David St. Jean | Urea derivatives which can be used to treat cancer |
| WO2023283425A1 (en) | 2021-07-09 | 2023-01-12 | Plexium, Inc. | Aryl compounds and pharmaceutical compositions that modulate ikzf2 |
| TW202329955A (zh) * | 2022-01-12 | 2023-08-01 | 英屬開曼群島商百濟神州有限公司 | 作為ＤＮＡ聚合酶Ｔｈｅｔａ抑製劑之噻唑并吡啶基醯胺衍生物 |
| EP4265247A1 (en) * | 2022-04-22 | 2023-10-25 | Université Paris Cité | Compounds inducing production of proteins by immune cells |
| US11970468B1 (en) | 2023-10-23 | 2024-04-30 | King Faisal University | 2-(benzo[d]oxazol-2-yl)-N′-(3,5-dichlorobenzoyloxy)acetimidamide as an antimicrobial compound |
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| FR2821721B1 (fr) * | 2001-03-08 | 2004-07-09 | Laurent Locatelli | Composition pour alimentation animale, utilisation de cette composition, et produit pour alimentation animale comprenant cette composition |
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-
2007
- 2007-10-16 PE PE2007001396A patent/PE20080888A1/es not_active Application Discontinuation
- 2007-10-16 AR ARP070104573A patent/AR063311A1/es not_active Application Discontinuation
- 2007-10-17 ES ES07854118.2T patent/ES2440253T3/es active Active
- 2007-10-17 WO PCT/US2007/081607 patent/WO2008048991A2/en active Application Filing
- 2007-10-17 JP JP2009533499A patent/JP5298022B2/ja not_active Expired - Fee Related
- 2007-10-17 AU AU2007311087A patent/AU2007311087B2/en not_active Ceased
- 2007-10-17 EP EP07854118.2A patent/EP2074089B1/en not_active Not-in-force
- 2007-10-17 MX MX2009004047A patent/MX2009004047A/es not_active Application Discontinuation
- 2007-10-17 KR KR1020097010003A patent/KR20090071642A/ko not_active Application Discontinuation
- 2007-10-17 CA CA002666880A patent/CA2666880A1/en not_active Abandoned
- 2007-10-17 TW TW096138922A patent/TW200829563A/zh unknown
- 2007-10-17 CL CL200702974A patent/CL2007002974A1/es unknown
- 2007-10-17 US US12/446,088 patent/US8222248B2/en not_active Expired - Fee Related
- 2007-10-17 BR BRPI0718478-6A2A patent/BRPI0718478A2/pt not_active IP Right Cessation
- 2007-10-17 RU RU2009118489/04A patent/RU2009118489A/ru not_active Application Discontinuation
