JP2010505958A - 神経防護作用組成物および方法 - Google Patents
神経防護作用組成物および方法 Download PDFInfo
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- JP2010505958A JP2010505958A JP2009532414A JP2009532414A JP2010505958A JP 2010505958 A JP2010505958 A JP 2010505958A JP 2009532414 A JP2009532414 A JP 2009532414A JP 2009532414 A JP2009532414 A JP 2009532414A JP 2010505958 A JP2010505958 A JP 2010505958A
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| JP2015519873A (ja) * | 2012-03-30 | 2015-07-16 | ネステク ソシエテ アノニム | ４−オキソ−２−ペンテン酸及び脳の健康 |
| JP2016511282A (ja) * | 2013-03-14 | 2016-04-14 | ユニバーシティ オブ マカオＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｍａｃａｕ | ヤクチ（益智（ａｌｐｉｎｉａｅｏｘｙｐｈｙｌｌａｅｆｒｕｃｔｕｓ））およびその全合成から単離される新規な抗神経変性天然化合物 |
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| GB2464813A (en) * | 2009-10-23 | 2010-05-05 | Univ Sheffield | Treatments for neurodegenerative disorders |
| WO2011160206A1 (en) | 2010-06-23 | 2011-12-29 | Morin Ryan D | Biomarkers for non-hodgkin lymphomas and uses thereof |
| BR112013005806B1 (pt) | 2010-09-10 | 2022-05-10 | Epizyme, Inc | Métodos para detectar se um indivíduo é um candidato para o tratamento com ou responsivo a um inibidor de ezh2 e usos terapêuticos do dito inibidor de ezh2 |
| US9175331B2 (en) | 2010-09-10 | 2015-11-03 | Epizyme, Inc. | Inhibitors of human EZH2, and methods of use thereof |
| CN103153297A (zh) * | 2010-09-14 | 2013-06-12 | 安元有限公司 | 类萜类似物及其用于治疗神经病症的用途 |
| WO2012094580A2 (en) | 2011-01-07 | 2012-07-12 | High Point Pharmaceuticals, Llc | Compounds that modulate oxidative stress |
| JO3363B1 (ar) | 2011-04-13 | 2019-03-13 | Epizyme Inc | مركبات بنزين مستبدلة بأريل أو أريل غير متجانس |
| TW201733984A (zh) | 2011-04-13 | 2017-10-01 | 雅酶股份有限公司 | 經取代之苯化合物 |
| US20140256767A1 (en) | 2011-10-31 | 2014-09-11 | The Broad Institute, Inc. | Direct inhibitors of keap1-nrf2 interaction as antioxidant inflammation modulators |
| US9394283B2 (en) | 2012-04-13 | 2016-07-19 | Epizyme, Inc. | Salt form of a human histone methyltransferase EZH2 inhibitor |
| PE20150887A1 (es) | 2012-10-15 | 2015-06-04 | Epizyme Inc | Compuestos de benceno sustituidos |
| WO2014093918A1 (en) | 2012-12-13 | 2014-06-19 | Warsaw Orthopedic, Inc. | Compositions and methods comprising polyethylene glycol and magnesium for treatment of neuronal injury |
| KR102142177B1 (ko) | 2013-10-16 | 2020-08-07 | 에피자임, 인코포레이티드 | Ezh2 억제용 하이드로클로라이드 염 형태 |
| EP3202400A4 (en) * | 2015-04-30 | 2018-06-13 | Institute Of Microbiology, Chinese Academy Of Sciences | Aromatic farnesyl compound and application thereof |
| US10123991B2 (en) | 2015-05-15 | 2018-11-13 | Global Biolife Inc. | Electrophilically enhanced phenolic compounds for treating inflammatory related diseases and disorders |
| EP3106160B8 (en) | 2015-06-15 | 2019-12-11 | Neuralia | Combination composition comprising huperzine |
| US10703701B2 (en) | 2015-12-17 | 2020-07-07 | Ptc Therapeutics, Inc. | Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| HUE065501T2 (hu) | 2018-08-20 | 2024-05-28 | Janssen Pharmaceutica Nv | A KEAP1-NRF2 protein-protein kölcsönhatás inhibitorok |
| CN111166885B (zh) * | 2020-01-16 | 2022-03-15 | 上海交通大学医学院 | 神经保护剂及其用途 |
| CN114588143B (zh) * | 2020-12-03 | 2023-06-06 | 中国科学院大连化学物理研究所 | 药物组合物及化合物作为或在制备阿片受体拮抗剂中的应用 |
| WO2023055733A1 (en) * | 2021-09-30 | 2023-04-06 | The Scripps Research Institute | Compounds for reducing neuroinflammation |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015519873A (ja) * | 2012-03-30 | 2015-07-16 | ネステク ソシエテ アノニム | ４−オキソ−２−ペンテン酸及び脳の健康 |
| JP2016511282A (ja) * | 2013-03-14 | 2016-04-14 | ユニバーシティ オブ マカオＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｍａｃａｕ | ヤクチ（益智（ａｌｐｉｎｉａｅｏｘｙｐｈｙｌｌａｅｆｒｕｃｔｕｓ））およびその全合成から単離される新規な抗神経変性天然化合物 |
| US10011555B2 (en) | 2013-03-14 | 2018-07-03 | University Of Macau | Methods of treating Parkinson's disease |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008108825A3 (en) | 2008-12-18 |
| EP2086318A2 (en) | 2009-08-12 |
| US20090042980A1 (en) | 2009-02-12 |
| CA2666461A1 (en) | 2008-09-12 |
| US20120296112A1 (en) | 2012-11-22 |
| WO2008108825A2 (en) | 2008-09-12 |
| EP2086318A4 (en) | 2009-12-23 |
| US8466311B2 (en) | 2013-06-18 |
| US8022246B2 (en) | 2011-09-20 |
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