JP2010503731A - 肺サーファクタント製剤および粘液クリアランスの促進方法 - Google Patents

肺サーファクタント製剤および粘液クリアランスの促進方法 Download PDF

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JP2010503731A
JP2010503731A JP2009529215A JP2009529215A JP2010503731A JP 2010503731 A JP2010503731 A JP 2010503731A JP 2009529215 A JP2009529215 A JP 2009529215A JP 2009529215 A JP2009529215 A JP 2009529215A JP 2010503731 A JP2010503731 A JP 2010503731A
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surfactant
patient
pulmonary
amino acid
pulmonary surfactant
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JP2010503731A5 (https=
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マーク・イー・ジョンソン
ロバート・シーガル
トーマス・ホフマン
ロバート・ジェイ・カペトラ
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ディスカバリー ラボラトリーズ，インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2009529215A 2006-09-19 2007-09-19 肺サーファクタント製剤および粘液クリアランスの促進方法 Pending JP2010503731A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84599106P 2006-09-19 2006-09-19
PCT/US2007/020260 WO2008036293A1 (en) 2006-09-19 2007-09-19 Pulmonary surfactant formulations and methods for promoting mucus clearance

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JP2010503731A true JP2010503731A (ja) 2010-02-04
JP2010503731A5 JP2010503731A5 (https=) 2010-11-11

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US (1) US8221772B2 (https=)
EP (1) EP2063903A1 (https=)
JP (1) JP2010503731A (https=)
KR (1) KR20090060348A (https=)
AU (1) AU2007297691B2 (https=)
BR (1) BRPI0717177A2 (https=)
CA (1) CA2663795A1 (https=)
MX (1) MX2009003002A (https=)
RU (1) RU2455021C2 (https=)
WO (1) WO2008036293A1 (https=)
ZA (1) ZA200902487B (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013540704A (ja) * 2010-08-23 2013-11-07 タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング 治療学的に有効な物質を含む加湿された粒子
JP2017222717A (ja) * 2011-06-07 2017-12-21 パリオン・サイエンシィズ・インコーポレーテッド 治療の方法
JP2019203001A (ja) * 2014-08-08 2019-11-28 シンセン ハイタイド バイオファーマシューティカル リミテッド 液体製剤組成物、薬物送達デバイス、ならびにそれらの調製および使用の方法

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US8669418B2 (en) 2005-12-22 2014-03-11 Vib Vzw Means and methods for mediating protein interference
CA2702094C (en) 2007-10-10 2018-05-01 Parion Sciences, Inc. Delivering osmolytes by nasal cannula
BR112012002291A2 (pt) * 2009-07-31 2016-11-29 Ethris Gmbh "polirribonucleotídeo com uma sequência que codifica uma proteína ou fragmento de proteína, implante, e, processo para a seleção de sequências de nucleotídeos"
US8945605B2 (en) 2011-06-07 2015-02-03 Parion Sciences, Inc. Aerosol delivery systems, compositions and methods
WO2015061412A1 (en) * 2013-10-22 2015-04-30 The Scripps Research Institute Methods and compositions for promoting bronchioli dilatation
GB201406225D0 (en) * 2014-04-07 2014-05-21 Hall Roderick L Treatment for respiratory disease
WO2017205383A1 (en) * 2016-05-23 2017-11-30 University Of Iowa Research Foundation Method of treating cystic fibrosis airway disease
AU2017298202A1 (en) * 2016-07-16 2019-02-07 Lauranell Harrison Burch Methods for treating cystic fibrosis and other diseases affecting mucosal surfaces
WO2018064529A1 (en) * 2016-09-29 2018-04-05 The Uab Research Foundation Methods and compositions for increasing mucus clearance
US11872262B2 (en) 2017-05-09 2024-01-16 Vib Vzw Means and methods for treating bacterial infections
CA3085944A1 (en) * 2017-12-21 2019-06-27 Civitas Therapeutics, Inc. Surfactant formulations for inhalation
US12427273B1 (en) 2020-05-15 2025-09-30 John E. Boyd Methods for treating respiratory distress and compositions for use in the same
GB202202297D0 (en) 2022-02-21 2022-04-06 Verona Pharma Plc Formulation production process
CN121620356A (zh) 2023-06-26 2026-03-06 维罗纳制药公司 包含恩塞芬汀的颗粒组合物
KR20250153517A (ko) 2024-04-18 2025-10-27 민현홍 신생아 호흡 곤란 증후군을 앓고 있는 조산아의 폐 전달을 개선하기 위한 미세기포 함유 에어로졸
WO2025231023A1 (en) * 2024-04-29 2025-11-06 Virginia Commonwealth University Aerosol surfactant therapy (ast) for respiratory distress syndrome (rds)

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WO2006074296A1 (en) * 2005-01-06 2006-07-13 Discovery Laboratories, Inc. Surfactant treatment regimen for treating or preventing bronchopulmonary dysplasia

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JPH06508619A (ja) * 1991-06-14 1994-09-29 ザ スクリップス リサーチ インスティテュート 合成肺界面活性ペプチド
JPH10316587A (ja) * 1997-04-28 1998-12-02 Scripps Res Inst:The 希釈した界面活性物質を含有する肺胞洗浄用医薬組成物
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013540704A (ja) * 2010-08-23 2013-11-07 タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング 治療学的に有効な物質を含む加湿された粒子
US9693955B2 (en) 2010-08-23 2017-07-04 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Humidified particles comprising a therapeutically active substance
JP2017222717A (ja) * 2011-06-07 2017-12-21 パリオン・サイエンシィズ・インコーポレーテッド 治療の方法
JP2019203001A (ja) * 2014-08-08 2019-11-28 シンセン ハイタイド バイオファーマシューティカル リミテッド 液体製剤組成物、薬物送達デバイス、ならびにそれらの調製および使用の方法

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Publication number Publication date
WO2008036293A1 (en) 2008-03-27
MX2009003002A (es) 2009-06-01
AU2007297691A1 (en) 2008-03-27
AU2007297691B2 (en) 2013-12-19
RU2009114825A (ru) 2010-10-27
US20080199410A1 (en) 2008-08-21
ZA200902487B (en) 2010-07-28
RU2455021C2 (ru) 2012-07-10
US8221772B2 (en) 2012-07-17
CA2663795A1 (en) 2008-03-27
BRPI0717177A2 (pt) 2013-10-08
KR20090060348A (ko) 2009-06-11
EP2063903A1 (en) 2009-06-03

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