JP2010502634A5 - - Google Patents
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- Publication number
- JP2010502634A5 JP2010502634A5 JP2009526819A JP2009526819A JP2010502634A5 JP 2010502634 A5 JP2010502634 A5 JP 2010502634A5 JP 2009526819 A JP2009526819 A JP 2009526819A JP 2009526819 A JP2009526819 A JP 2009526819A JP 2010502634 A5 JP2010502634 A5 JP 2010502634A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- composition
- polymer
- group
- modifying compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 22
- 229920000642 polymer Polymers 0.000 claims 13
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical class OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical class CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 9
- 239000002253 acid Substances 0.000 claims 9
- 150000001875 compounds Chemical class 0.000 claims 7
- UIERETOOQGIECD-UHFFFAOYSA-N Angelic acid Natural products CC=C(C)C(O)=O UIERETOOQGIECD-UHFFFAOYSA-N 0.000 claims 6
- 229920002125 Sokalan® Polymers 0.000 claims 6
- 239000004584 polyacrylic acid Substances 0.000 claims 6
- 238000000034 method Methods 0.000 claims 4
- KHQDAOSIOHTJCX-OWOJBTEDSA-N (E)-3-(4,4-dihydroxycyclohexa-1,5-dien-1-yl)prop-2-enoic acid Chemical compound OC(=O)\C=C\C1=CCC(O)(O)C=C1 KHQDAOSIOHTJCX-OWOJBTEDSA-N 0.000 claims 3
- UIERETOOQGIECD-ARJAWSKDSA-M 2-Methyl-2-butenoic acid Natural products C\C=C(\C)C([O-])=O UIERETOOQGIECD-ARJAWSKDSA-M 0.000 claims 3
- RYNDYESLUKWOEE-UHFFFAOYSA-N 2-benzylprop-2-enoic acid Chemical compound OC(=O)C(=C)CC1=CC=CC=C1 RYNDYESLUKWOEE-UHFFFAOYSA-N 0.000 claims 3
- FQHUWSPRTMWLFA-UHFFFAOYSA-N 2-cyclohexylprop-2-enoic acid Chemical compound OC(=O)C(=C)C1CCCCC1 FQHUWSPRTMWLFA-UHFFFAOYSA-N 0.000 claims 3
- ONPJWQSDZCGSQM-UHFFFAOYSA-N 2-phenylprop-2-enoic acid Chemical compound OC(=O)C(=C)C1=CC=CC=C1 ONPJWQSDZCGSQM-UHFFFAOYSA-N 0.000 claims 3
- NAORGNSYBDQEPT-UHFFFAOYSA-N 3-phenylprop-2-enoic acid Chemical compound OC(=O)C=CC1=CC=CC=C1.OC(=O)C=CC1=CC=CC=C1 NAORGNSYBDQEPT-UHFFFAOYSA-N 0.000 claims 3
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 3
- 229920002845 Poly(methacrylic acid) Polymers 0.000 claims 3
- 150000007513 acids Chemical class 0.000 claims 3
- UIERETOOQGIECD-ARJAWSKDSA-N angelic acid Chemical compound C\C=C(\C)C(O)=O UIERETOOQGIECD-ARJAWSKDSA-N 0.000 claims 3
- RLYNGYDVXRKEOO-SQQVDAMQSA-N but-2-enoic acid;(e)-but-2-enoic acid Chemical compound CC=CC(O)=O.C\C=C\C(O)=O RLYNGYDVXRKEOO-SQQVDAMQSA-N 0.000 claims 3
- 239000001913 cellulose Chemical class 0.000 claims 3
- 229920002678 cellulose Chemical class 0.000 claims 3
- PMOWTIHVNWZYFI-UHFFFAOYSA-N o-Coumaric acid Natural products OC(=O)C=CC1=CC=CC=C1O PMOWTIHVNWZYFI-UHFFFAOYSA-N 0.000 claims 3
- 229920005862 polyol Chemical class 0.000 claims 3
- 150000003077 polyols Chemical class 0.000 claims 3
- 239000003755 preservative agent Substances 0.000 claims 3
- 230000002335 preservative effect Effects 0.000 claims 3
- UIERETOOQGIECD-ONEGZZNKSA-N tiglic acid Chemical compound C\C=C(/C)C(O)=O UIERETOOQGIECD-ONEGZZNKSA-N 0.000 claims 3
- UAXOELSVPTZZQG-UHFFFAOYSA-N tiglic acid Natural products CC(C)=C(C)C(O)=O UAXOELSVPTZZQG-UHFFFAOYSA-N 0.000 claims 3
- PMOWTIHVNWZYFI-AATRIKPKSA-N trans-2-coumaric acid Chemical compound OC(=O)\C=C\C1=CC=CC=C1O PMOWTIHVNWZYFI-AATRIKPKSA-N 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 2
- 239000002260 anti-inflammatory agent Substances 0.000 claims 2
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 2
- 239000000043 antiallergic agent Substances 0.000 claims 2
- 229960005475 antiinfective agent Drugs 0.000 claims 2
- 239000004599 antimicrobial Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000003431 cross linking reagent Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84103606P | 2006-08-30 | 2006-08-30 | |
| PCT/US2007/076700 WO2008027793A2 (en) | 2006-08-30 | 2007-08-24 | Ophthalmic pharmaceutical compositions and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010502634A JP2010502634A (ja) | 2010-01-28 |
| JP2010502634A5 true JP2010502634A5 (enExample) | 2010-10-07 |
Family
ID=38969502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009526819A Pending JP2010502634A (ja) | 2006-08-30 | 2007-08-24 | 眼科用医薬組成物とその利用法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20080057022A1 (enExample) |
| EP (1) | EP2068821A2 (enExample) |
| JP (1) | JP2010502634A (enExample) |
| CN (1) | CN101636146A (enExample) |
| WO (1) | WO2008027793A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100087550A1 (en) | 2008-10-06 | 2010-04-08 | Zora Marlowe | Formulations with a Tertiary Amine Oxide |
| US9125405B2 (en) * | 2008-10-28 | 2015-09-08 | Bausch & Lomb Incorporated | Contact lens solution with a tertiary amine oxide |
| US20110029950A1 (en) * | 2009-07-30 | 2011-02-03 | Iftach Ragoler | Computer-readable media, methods and computer systems for designing a software application graphically |
| GB2484843A (en) * | 2009-10-15 | 2012-04-25 | Johnson Matthey Plc | Polymorphs of Bromfenac sodium |
| GB201411423D0 (en) * | 2014-06-26 | 2014-08-13 | Ge Healthcare As | Lipid sterilisation method |
| AU2021381495A1 (en) | 2020-11-23 | 2023-06-22 | Sight Sciences, Inc. | Formulations and methods for treating conditions of the eye |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2798053A (en) * | 1952-09-03 | 1957-07-02 | Goodrich Co B F | Carboxylic polymers |
| US4192827A (en) * | 1974-06-27 | 1980-03-11 | Ciba-Geigy Corporation | Water-insoluble hydrophilic copolymers |
| US4136250A (en) * | 1977-07-20 | 1979-01-23 | Ciba-Geigy Corporation | Polysiloxane hydrogels |
| US4883658A (en) * | 1986-04-28 | 1989-11-28 | Holly Frank J | Ophthalmic solution for treatment of dry-eye syndrome |
| US4804539A (en) * | 1986-07-28 | 1989-02-14 | Liposome Technology, Inc. | Ophthalmic liposomes |
| US5278151A (en) * | 1987-04-02 | 1994-01-11 | Ocular Research Of Boston, Inc. | Dry eye treatment solution |
| US4914088A (en) * | 1987-04-02 | 1990-04-03 | Thomas Glonek | Dry eye treatment solution and method |
| US5188826A (en) * | 1988-02-08 | 1993-02-23 | Insite Vision Incorporated | Topical ophthalmic suspensions |
| US5075104A (en) * | 1989-03-31 | 1991-12-24 | Alcon Laboratories, Inc. | Ophthalmic carboxy vinyl polymer gel for dry eye syndrome |
| ZA912797B (en) * | 1990-05-29 | 1992-12-30 | Boston Ocular Res | Dry eye treatment process and solution |
| EP0459148B1 (en) * | 1990-05-29 | 1996-01-03 | Ocular Research Of Boston Inc. | Dry eye treatment composition |
| ZA927277B (en) * | 1991-10-02 | 1993-05-19 | Boston Ocular Res | Dry eye treatment process and solution. |
| TW274516B (enExample) * | 1993-11-12 | 1996-04-21 | Ciba Geigy Ag | |
| SE9401109D0 (sv) * | 1994-03-31 | 1994-03-31 | Leiras Oy | Opthalmic composition II |
| US7056893B2 (en) * | 1999-03-31 | 2006-06-06 | Insite Vision, Inc. | Topical treatment for prevention of ocular infections |
| US7001615B1 (en) * | 2001-12-07 | 2006-02-21 | Alcon, Inc. | Sustained release ophthalmic, otic and nasal suspension |
| TWI336257B (en) * | 2003-06-13 | 2011-01-21 | Alcon Inc | Ophthalmic compositions containing a synergistic combination of three polymers |
| CA2839928C (en) * | 2003-06-13 | 2016-10-04 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of two polymers |
| US8569367B2 (en) * | 2004-11-16 | 2013-10-29 | Allergan, Inc. | Ophthalmic compositions and methods for treating eyes |
| TWI358290B (en) * | 2004-12-02 | 2012-02-21 | Alcon Inc | Topical nepafenac formulations |
| WO2007005421A2 (en) * | 2005-07-01 | 2007-01-11 | Bausch & Lomb Incorporated | Long lasting alginate dry eye, related methods of manufacture and methods of use |
| WO2007058935A2 (en) * | 2005-11-14 | 2007-05-24 | Bausch & Lomb Incorporated | Ophthalmic composition for dry eye therapy |
| US20070287752A1 (en) * | 2006-06-08 | 2007-12-13 | Burke Susan E | Ophthalmic Compositions Comprising A Branched, Glycerol Compound |
-
2007
- 2007-08-21 US US11/842,394 patent/US20080057022A1/en not_active Abandoned
- 2007-08-24 EP EP07841297A patent/EP2068821A2/en not_active Withdrawn
- 2007-08-24 CN CN200780031963A patent/CN101636146A/zh active Pending
- 2007-08-24 JP JP2009526819A patent/JP2010502634A/ja active Pending
- 2007-08-24 WO PCT/US2007/076700 patent/WO2008027793A2/en not_active Ceased
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