JP2010502601A5 - - Google Patents
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- Publication number
- JP2010502601A5 JP2010502601A5 JP2009526573A JP2009526573A JP2010502601A5 JP 2010502601 A5 JP2010502601 A5 JP 2010502601A5 JP 2009526573 A JP2009526573 A JP 2009526573A JP 2009526573 A JP2009526573 A JP 2009526573A JP 2010502601 A5 JP2010502601 A5 JP 2010502601A5
- Authority
- JP
- Japan
- Prior art keywords
- plasminogen
- pharmaceutical composition
- compound
- kringle
- wound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000013566 Plasminogen Human genes 0.000 claims 16
- 108010051456 Plasminogen Proteins 0.000 claims 16
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 150000001875 compounds Chemical class 0.000 claims 10
- 208000027418 Wounds and injury Diseases 0.000 claims 8
- 208000015181 infectious disease Diseases 0.000 claims 5
- 230000002458 infectious effect Effects 0.000 claims 5
- 208000035143 Bacterial infection Diseases 0.000 claims 4
- 208000022362 bacterial infectious disease Diseases 0.000 claims 4
- 108010049112 miniplasminogen Proteins 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 208000028169 periodontal disease Diseases 0.000 claims 4
- 230000003239 periodontal effect Effects 0.000 claims 4
- 230000002265 prevention Effects 0.000 claims 4
- 230000002797 proteolythic effect Effects 0.000 claims 4
- 230000001580 bacterial effect Effects 0.000 claims 3
- 108010087750 lysyl-plasminogen Proteins 0.000 claims 3
- 102000004127 Cytokines Human genes 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 2
- 206010017533 Fungal infection Diseases 0.000 claims 2
- 101000605403 Homo sapiens Plasminogen Proteins 0.000 claims 2
- 208000031888 Mycoses Diseases 0.000 claims 2
- 208000036142 Viral infection Diseases 0.000 claims 2
- 230000002708 enhancing effect Effects 0.000 claims 2
- 230000035876 healing Effects 0.000 claims 2
- 210000004969 inflammatory cell Anatomy 0.000 claims 2
- 230000029774 keratinocyte migration Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000001338 necrotic effect Effects 0.000 claims 2
- 230000001737 promoting effect Effects 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 230000007838 tissue remodeling Effects 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 241000021559 Dicerandra Species 0.000 claims 1
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- 206010018296 Gingivitis ulcerative Diseases 0.000 claims 1
- 235000010654 Melissa officinalis Nutrition 0.000 claims 1
- 206010028116 Mucosal inflammation Diseases 0.000 claims 1
- 201000010927 Mucositis Diseases 0.000 claims 1
- 208000006389 Peri-Implantitis Diseases 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 238000002316 cosmetic surgery Methods 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 230000008021 deposition Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 208000007565 gingivitis Diseases 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 239000000865 liniment Substances 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000002324 mouth wash Substances 0.000 claims 1
- 229940051866 mouthwash Drugs 0.000 claims 1
- 239000006072 paste Substances 0.000 claims 1
- 201000001245 periodontitis Diseases 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 238000007910 systemic administration Methods 0.000 claims 1
- 229940034610 toothpaste Drugs 0.000 claims 1
- 239000000606 toothpaste Substances 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82366506P | 2006-08-28 | 2006-08-28 | |
| US60/823,665 | 2006-08-28 | ||
| US94411107P | 2007-06-15 | 2007-06-15 | |
| US60/944,111 | 2007-06-15 | ||
| PCT/SE2007/050586 WO2008027000A2 (en) | 2006-08-28 | 2007-08-28 | Novel drug target of preventing and treating periodontal disease, improving healing of periodontal wounds and promoting oral health |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010502601A JP2010502601A (ja) | 2010-01-28 |
| JP2010502601A5 true JP2010502601A5 (https=) | 2010-10-21 |
| JP5566106B2 JP5566106B2 (ja) | 2014-08-06 |
Family
ID=39136398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009526573A Expired - Fee Related JP5566106B2 (ja) | 2006-08-28 | 2007-08-28 | 歯周病の阻止および治療、歯周創傷の治癒の改善および口腔衛生の促進を目的とする新規薬物 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20100028321A1 (https=) |
| EP (1) | EP2056865B1 (https=) |
| JP (1) | JP5566106B2 (https=) |
| AU (1) | AU2007290882B2 (https=) |
| CA (1) | CA2662083C (https=) |
| DK (1) | DK2056865T3 (https=) |
| ES (1) | ES2453496T3 (https=) |
| WO (1) | WO2008027000A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8318661B2 (en) | 2006-08-28 | 2012-11-27 | Omnio Healer Ab | Candidates against infection |
| US20130164228A1 (en) * | 2011-12-21 | 2013-06-27 | Colgate-Palmolive Company | Compositions comprising gallates and gallamides |
| US9723558B2 (en) | 2012-04-27 | 2017-08-01 | Qualcomm Incorporated | Method and apparatus for signaling in dense network operations |
| CN104721621A (zh) * | 2015-03-24 | 2015-06-24 | 孟勇 | 一种治疗种植体周围炎的药物组合物及其应用 |
| JP2018524067A (ja) | 2015-06-11 | 2018-08-30 | アットウィル メディカル ソルーションズ インコーポレイテッド | アンチトロンビン−ヘパリン組成物を利用する医療機器、システムおよび方法 |
| TWI801331B (zh) * | 2015-11-03 | 2023-05-11 | 美商波麥堤克生物治療股份有限公司 | 纖維蛋白溶酶原缺乏症之纖維蛋白溶酶原替代療法 |
| AU2016354100B2 (en) * | 2015-11-10 | 2023-11-30 | Yale University | Compositions and methods for treating autoimmune diseases and cancers |
| DK3391902T5 (da) | 2015-12-18 | 2024-09-23 | Talengen Int Ltd | Plasminogen til anvendelse i behandlingen af diabetisk angiokardiopati |
| CN108463235A (zh) * | 2015-12-18 | 2018-08-28 | 泰伦基国际有限公司 | 一种用于预防和治疗宫颈糜烂的方法 |
| WO2018107686A1 (zh) | 2016-12-15 | 2018-06-21 | 深圳瑞健生命科学研究院有限公司 | 一种治疗动脉粥样硬化及其并发症的方法 |
| TWI746581B (zh) * | 2016-12-15 | 2021-11-21 | 大陸商深圳瑞健生命科學硏究院有限公司 | 纖溶酶原在製備預防和治療脂質腎損傷之藥劑上的用途 |
| JP7168990B2 (ja) | 2016-12-15 | 2022-11-10 | タレンゲン インターナショナル リミテッド | 肥満症を予防および治療するための方法および薬物 |
| TWI677348B (zh) * | 2016-12-15 | 2019-11-21 | 大陸商深圳瑞健生命科學研究院有限公司 | 一種改善心臟病變的方法 |
| TWI868051B (zh) | 2017-06-23 | 2025-01-01 | 美商波麥堤克生物治療股份有限公司 | 與pai-1過表現相關之病狀的纖維蛋白溶酶原治療 |
| EP4094775A4 (en) * | 2020-02-06 | 2023-04-19 | Talengen International Limited | METHODS AND MEDICATIONS FOR THE PREVENTION AND TREATMENT OF MULTIPLE SCLEROSIS |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3023143A (en) | 1959-10-14 | 1962-02-27 | American Cyanamid Co | Process for preparing a veterinary composition |
| AT402367B (de) * | 1990-10-11 | 1997-04-25 | Immuno Ag | Pharmazeutische zubereitung auf basis von lys-plasminogen |
| US6054122A (en) * | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| US5792835A (en) * | 1991-09-05 | 1998-08-11 | Baxter International Inc. | Method of preparing a topical fibrinogen complex |
| US5397578A (en) | 1994-03-29 | 1995-03-14 | Tovarischestvo S Ogranichennoi Otvetstvennostiju "Taurus" | Method of treatment of chronic purulent inflammations of ear in children |
| US6420622B1 (en) | 1997-08-01 | 2002-07-16 | 3M Innovative Properties Company | Medical article having fluid control film |
| JP2003513682A (ja) * | 1998-07-24 | 2003-04-15 | ファーマカル、バイオテクノロジーズ、インコーポレーテッド | 骨組織復元システムおよび方法 |
| AU3862900A (en) * | 1999-03-01 | 2000-09-21 | Uab Research Foundation | Porous tissue scaffolding materials and uses thereof |
| US20030026794A1 (en) * | 2001-07-31 | 2003-02-06 | Howard Fein | Selective enzyme treatment of skin conditions |
| US7067492B2 (en) * | 2001-09-06 | 2006-06-27 | Omnio Ab | Method of promoting healing of a tympanic membrane perforation |
| NZ533029A (en) * | 2001-11-26 | 2006-05-26 | Genentech Inc | Composition useful for removal of fibrin-bound blood clot from a catheter comprises water, a plasminogen activator and an alcohol |
| MXPA04007585A (es) | 2002-02-06 | 2005-09-20 | N Zyme Biotec Gmbh | Metodo para la produccion de proteinas recombinantes en microorganismos. |
| CN1420126A (zh) | 2002-07-10 | 2003-05-28 | 牛勃 | 一种重组人纤溶酶原Kringle5突变体蛋白rhPK－5的制备方法 |
| US8318661B2 (en) | 2006-08-28 | 2012-11-27 | Omnio Healer Ab | Candidates against infection |
-
2007
- 2007-08-28 ES ES07794196.1T patent/ES2453496T3/es active Active
- 2007-08-28 WO PCT/SE2007/050586 patent/WO2008027000A2/en not_active Ceased
- 2007-08-28 JP JP2009526573A patent/JP5566106B2/ja not_active Expired - Fee Related
- 2007-08-28 AU AU2007290882A patent/AU2007290882B2/en not_active Ceased
- 2007-08-28 CA CA2662083A patent/CA2662083C/en not_active Expired - Fee Related
- 2007-08-28 DK DK07794196.1T patent/DK2056865T3/en active
- 2007-08-28 US US12/439,516 patent/US20100028321A1/en not_active Abandoned
- 2007-08-28 EP EP07794196.1A patent/EP2056865B1/en not_active Not-in-force
-
2015
- 2015-10-23 US US14/921,758 patent/US10086052B2/en active Active
-
2018
- 2018-08-28 US US16/114,940 patent/US20180360931A1/en not_active Abandoned
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