JP2010502585A5 - - Google Patents
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- Publication number
- JP2010502585A5 JP2010502585A5 JP2009526190A JP2009526190A JP2010502585A5 JP 2010502585 A5 JP2010502585 A5 JP 2010502585A5 JP 2009526190 A JP2009526190 A JP 2009526190A JP 2009526190 A JP2009526190 A JP 2009526190A JP 2010502585 A5 JP2010502585 A5 JP 2010502585A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- amino acid
- acid residue
- compound according
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 7
- 125000000539 amino acid group Chemical group 0.000 claims 3
- 239000004475 Arginine Substances 0.000 claims 2
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 2
- 235000003704 aspartic acid Nutrition 0.000 claims 2
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims 2
- 238000002059 diagnostic imaging Methods 0.000 claims 2
- 239000012216 imaging agent Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- NMDDZEVVQDPECF-LURJTMIESA-N (2s)-2,7-diaminoheptanoic acid Chemical compound NCCCCC[C@H](N)C(O)=O NMDDZEVVQDPECF-LURJTMIESA-N 0.000 claims 1
- VILCJCGEZXAXTO-UHFFFAOYSA-N 2,2,2-tetramine Chemical compound NCCNCCNCCN VILCJCGEZXAXTO-UHFFFAOYSA-N 0.000 claims 1
- JHALWMSZGCVVEM-UHFFFAOYSA-N 2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetic acid Chemical compound OC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CC1 JHALWMSZGCVVEM-UHFFFAOYSA-N 0.000 claims 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- NTWVQPHTOUKMDI-YFKPBYRVSA-N N-Methyl-arginine Chemical compound CN[C@H](C(O)=O)CCCN=C(N)N NTWVQPHTOUKMDI-YFKPBYRVSA-N 0.000 claims 1
- WDLRUFUQRNWCPK-UHFFFAOYSA-N Tetraxetan Chemical compound OC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 WDLRUFUQRNWCPK-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 235000001014 amino acid Nutrition 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 238000002405 diagnostic procedure Methods 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 235000013922 glutamic acid Nutrition 0.000 claims 1
- 239000004220 glutamic acid Substances 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 238000011503 in vivo imaging Methods 0.000 claims 1
- 235000018977 lysine Nutrition 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 125000006850 spacer group Chemical group 0.000 claims 1
- 150000003573 thiols Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82368206P | 2006-08-28 | 2006-08-28 | |
| PCT/IB2007/002479 WO2008026040A2 (en) | 2006-08-28 | 2007-08-28 | 68ga-labeled peptide-based radiopharmaceuticals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010502585A JP2010502585A (ja) | 2010-01-28 |
| JP2010502585A5 true JP2010502585A5 (https=) | 2011-09-15 |
Family
ID=38961954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009526190A Pending JP2010502585A (ja) | 2006-08-28 | 2007-08-28 | ６８Ｇａ標識ペプチド系放射性医薬品 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20100233082A1 (https=) |
| EP (1) | EP2056886A2 (https=) |
| JP (1) | JP2010502585A (https=) |
| CN (1) | CN101528270A (https=) |
| WO (1) | WO2008026040A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2279011B1 (en) * | 2008-04-30 | 2017-10-25 | Siemens Medical Solutions USA, Inc. | Substrate based pet imaging agents |
| GB0814722D0 (en) * | 2008-08-12 | 2008-09-17 | Ge Healthcare Ltd | Treatment monitoring |
| WO2011021390A1 (ja) * | 2009-08-20 | 2011-02-24 | 富士フイルムＲｉファーマ株式会社 | ビスホスホン酸誘導体及びその放射性金属核種標識体 |
| ITFI20110180A1 (it) * | 2011-08-12 | 2013-02-13 | Advanced Accelerator Applic S A | Processo per la preparazione di complessi di 68ga. |
| ES2972124T3 (es) * | 2012-12-03 | 2024-06-11 | Curasight As | Péptidos marcados con un radionúclido que emite positrones para obtención de imágenes de PET del uPAR humana |
| GB201511036D0 (en) * | 2015-06-23 | 2015-08-05 | Guy S And St Thomas Hospital Nhs Foundation Trust | Imaging method |
| WO2018138372A1 (en) * | 2017-01-30 | 2018-08-02 | Vect-Horus | Compositions and methods for cancer imaging and radiotherapy |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2405469C (en) * | 2000-04-12 | 2012-03-20 | Amersham Health As | Integrin binding peptide derivatives |
| NO20004795D0 (no) * | 2000-09-26 | 2000-09-26 | Nycomed Imaging As | Peptidbaserte forbindelser |
| BRPI0210886B8 (pt) * | 2001-07-10 | 2021-05-25 | Amersham Health As | composto, composição farmacêutica, uso de um composto, e, métodos de geração de imagens, de monitoração do efeito do tratamento de um corpo humano ou animal com uma droga para combater uma condição associada com câncer e de tratamento de câncer ou de uma doença relacionada em um corpo humano ou animal |
| GB0308408D0 (en) * | 2003-04-11 | 2003-05-21 | Amersham Plc | Microwave activation |
| DE602005025911D1 (de) * | 2004-11-22 | 2011-02-24 | Ge Healthcare As | Kontrastmittel für eine extrazelluläre matrix |
| GB0428012D0 (en) * | 2004-12-22 | 2005-01-26 | Hammersmith Imanet Ltd | Radiolabelling methods |
-
2007
- 2007-08-28 EP EP07804849A patent/EP2056886A2/en not_active Withdrawn
- 2007-08-28 JP JP2009526190A patent/JP2010502585A/ja active Pending
- 2007-08-28 US US12/376,800 patent/US20100233082A1/en not_active Abandoned
- 2007-08-28 WO PCT/IB2007/002479 patent/WO2008026040A2/en not_active Ceased
- 2007-08-28 CN CNA2007800402050A patent/CN101528270A/zh active Pending
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