JP2010501594A5 - - Google Patents

Download PDF

Info

Publication number
JP2010501594A5
JP2010501594A5 JP2009525853A JP2009525853A JP2010501594A5 JP 2010501594 A5 JP2010501594 A5 JP 2010501594A5 JP 2009525853 A JP2009525853 A JP 2009525853A JP 2009525853 A JP2009525853 A JP 2009525853A JP 2010501594 A5 JP2010501594 A5 JP 2010501594A5
Authority
JP
Japan
Prior art keywords
variable region
glycoprotein
hcv
modified
linker sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009525853A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010501594A6 (ja
JP2010501594A (ja
JP5674310B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/AU2007/001221 external-priority patent/WO2008022401A1/en
Publication of JP2010501594A publication Critical patent/JP2010501594A/ja
Publication of JP2010501594A6 publication Critical patent/JP2010501594A6/ja
Publication of JP2010501594A5 publication Critical patent/JP2010501594A5/ja
Application granted granted Critical
Publication of JP5674310B2 publication Critical patent/JP5674310B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2009525853A 2006-08-25 2007-08-24 組換えhcv e2糖タンパク質 Expired - Fee Related JP5674310B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
AU2006904635 2006-08-25
AU2006904635A AU2006904635A0 (en) 2006-08-25 Recombinant E2 Envelope Glycoprotein for Improved Treatment of HCV virus
AU2006906090 2006-11-01
AU2006906090A AU2006906090A0 (en) 2006-11-01 Recombinant HCV E2 Glycoprotein for use in HCV Vaccine Treatment
AU2006906282A AU2006906282A0 (en) 2006-11-10 Recombinant HCV E2 Glycoprotein for use in HCV Vaccine Treatment
AU2006906282 2006-11-10
PCT/AU2007/001221 WO2008022401A1 (en) 2006-08-25 2007-08-24 Recombinant hcv e2 glycoprotein

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014185095A Division JP5999524B2 (ja) 2006-08-25 2014-09-11 組換えhcve2糖タンパク質

Publications (4)

Publication Number Publication Date
JP2010501594A JP2010501594A (ja) 2010-01-21
JP2010501594A6 JP2010501594A6 (ja) 2010-04-15
JP2010501594A5 true JP2010501594A5 (OSRAM) 2010-10-07
JP5674310B2 JP5674310B2 (ja) 2015-02-25

Family

ID=39106399

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009525853A Expired - Fee Related JP5674310B2 (ja) 2006-08-25 2007-08-24 組換えhcv e2糖タンパク質
JP2014185095A Expired - Fee Related JP5999524B2 (ja) 2006-08-25 2014-09-11 組換えhcve2糖タンパク質

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014185095A Expired - Fee Related JP5999524B2 (ja) 2006-08-25 2014-09-11 組換えhcve2糖タンパク質

Country Status (8)

Country Link
US (2) US8535686B2 (OSRAM)
EP (1) EP2061805B1 (OSRAM)
JP (2) JP5674310B2 (OSRAM)
KR (1) KR101500017B1 (OSRAM)
CN (1) CN101563362B (OSRAM)
AU (1) AU2007288129B2 (OSRAM)
CA (1) CA2661814A1 (OSRAM)
WO (1) WO2008022401A1 (OSRAM)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101500017B1 (ko) * 2006-08-25 2015-03-09 더 맥파레인 버넷 인스티튜트 포 메디칼 리서치 앤드 퍼블릭 헬스 리미티드 재조합 hcv e2 당단백질
US9758794B2 (en) 2008-04-22 2017-09-12 Rutgers, The State University Of New Jersey HCV E2 construct compositions and methods
US20110091495A1 (en) * 2008-04-22 2011-04-21 Rutgers, The State University Of New Jersey Hcv e2 construct compositions and methods
AU2009254168A1 (en) * 2008-06-03 2009-12-10 Okairos Ag A vaccine for the prevention and therapy of HCV infections
CA2658714A1 (en) * 2009-03-17 2010-09-17 Thomas Krey Hcv-derived polypeptides and uses thereof
CN102199613A (zh) * 2010-03-25 2011-09-28 国立大学法人东京大学 感染性丙型肝炎病毒高生产hcv突变体及其应用
CA2840993A1 (en) 2010-08-04 2012-02-09 The Macfarlane Burnet Institute For Medical Research And Public Health Ltd Modified hepatitis c virus proteins
CN104324373B (zh) * 2010-11-26 2018-10-09 麦克法兰博尼特医学健康研究公司 组合物及其制备方法
WO2013033319A2 (en) * 2011-08-30 2013-03-07 The Board Of Trustees Of The Leland Stanford Junior University A cluster of neutralizing antibodies to hepatitis c virus
CN103102394B (zh) * 2013-02-27 2014-06-25 北京大学人民医院 丙型肝炎病毒b细胞表位肽puhi49及其应用
CN110049993A (zh) * 2016-09-29 2019-07-23 麦克法兰布奈特医疗研究与公共健康研究所有限公司 组装的糖蛋白
CN114630698A (zh) * 2019-07-26 2022-06-14 斯克里普斯研究学院 经改造hcv e2免疫原和相关疫苗组合物
CA3178547A1 (en) * 2020-05-11 2021-11-18 Heidi Drummer A hepatitis c nucleic acid vaccine comprising a variable domain deleted e2 polypeptide
CN112730851B (zh) * 2021-03-31 2021-06-22 南京立顶医疗科技有限公司 一种高灵敏SARS-CoV-2中和抗体的检测方法、检测试剂盒

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2176342T5 (es) 1994-10-21 2010-02-09 Innogenetics N.V. Secuencias del genotipo 7 del virus de la hepatitis c y su utilizacion como agentes profilacticos, terapeuticos y de diagnosticos.
EP1127170A4 (en) * 1998-11-05 2005-04-27 Univ Leland Stanford Junior HUMAN MONOCLONAL ANTIBODIES OF THE HEPATITIS C VIRUS (HCV) PAN
AU7602800A (en) * 1999-09-23 2001-04-24 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Hepatitis c virus envelope two protein (e2) which lacks all or part of the hypervariable region one (hvr1), corresponding nucleic acids, chimeric viruses and uses thereof
AU2001292667A1 (en) 2000-09-13 2002-03-26 Hawaii Biotechnology Group, Inc. Immunogenic composition of hepatitis c and methods of use thereof
MXPA03009626A (es) * 2001-04-24 2004-06-30 Innogenetics Nv Construcciones y metodo para la expresion de proteinas recombinantes de la envoltura viral de hcv.
IL145440A0 (en) 2001-09-13 2002-06-30 Xtl Biopharmaceuticals Ltd Synthetic hcv envelope proteins and their use for vaccination
CA2552949C (en) * 2004-01-07 2012-10-02 Third Wave Technologies, Inc. Determination of hepatitis c virus genotype
KR101500017B1 (ko) * 2006-08-25 2015-03-09 더 맥파레인 버넷 인스티튜트 포 메디칼 리서치 앤드 퍼블릭 헬스 리미티드 재조합 hcv e2 당단백질

Similar Documents

Publication Publication Date Title
JP2010501594A5 (OSRAM)
US6951646B1 (en) Anti hepatitis C virus antibody and uses thereof
Goh et al. Neutralizing monoclonal antibodies to the E2 protein of chikungunya virus protects against disease in a mouse model
Keck et al. Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice
ES2926511T3 (es) Anticuerpos anti-CLEVER-1 humanizados y utilización de los mismos
JP2012504602A5 (OSRAM)
EA201170353A1 (ru) Антитела против гепатита с и их применение
JP2012531219A5 (OSRAM)
JP2018512124A5 (OSRAM)
JP2005528914A5 (OSRAM)
Arribillaga et al. Enhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus
JP2018537117A5 (OSRAM)
JP2006504645A5 (OSRAM)
JP5897024B2 (ja) 組成物および方法
JP2008532559A5 (OSRAM)
JP2006523185A5 (OSRAM)
US20080248042A1 (en) Monoclonal antibody cross-reactive against infective agent causing a B-cell expansion and IgG-Fc
CN105254756B (zh) 一种针对丙型肝炎病毒包膜蛋白e2的单克隆抗体及应用
El-Awady et al. Conserved peptides within the E2 region of Hepatitis C virus induce humoral and cellular responses in goats
TWI432211B (zh) 與登革病毒相關之胜肽及抗體以及其用途
EP2705369B1 (fr) Procédé pour la détection d'une infection par le virus de la dengue
Takao et al. Antibody reactive to a hepatitis C virus (HCV)‐derived peptide capable of inducing HLA‐A2 restricted cytotoxic T lymphocytes is detectable in a majority of HCV‐infected individuals without HLA‐A2 restriction
Karsten et al. A novel series of anti-human glycophorin A (CD235a) antibodies defining five extra-and intracellular epitopes
CN107286237B (zh) 一种抗丙型肝炎病毒抗体的获取以及应用
CN113876939A (zh) 登革次单位疫苗组成物