CA2661814A1 - Recombinant hcv e2 glycoprotein - Google Patents
Recombinant hcv e2 glycoprotein Download PDFInfo
- Publication number
- CA2661814A1 CA2661814A1 CA002661814A CA2661814A CA2661814A1 CA 2661814 A1 CA2661814 A1 CA 2661814A1 CA 002661814 A CA002661814 A CA 002661814A CA 2661814 A CA2661814 A CA 2661814A CA 2661814 A1 CA2661814 A1 CA 2661814A1
- Authority
- CA
- Canada
- Prior art keywords
- hcv
- glycoprotein
- modified
- variable region
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2319/00—Fusion polypeptide
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
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- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2006904635 | 2006-08-25 | ||
| AU2006904635A AU2006904635A0 (en) | 2006-08-25 | Recombinant E2 Envelope Glycoprotein for Improved Treatment of HCV virus | |
| AU2006906090 | 2006-11-01 | ||
| AU2006906090A AU2006906090A0 (en) | 2006-11-01 | Recombinant HCV E2 Glycoprotein for use in HCV Vaccine Treatment | |
| AU2006906282 | 2006-11-10 | ||
| AU2006906282A AU2006906282A0 (en) | 2006-11-10 | Recombinant HCV E2 Glycoprotein for use in HCV Vaccine Treatment | |
| PCT/AU2007/001221 WO2008022401A1 (en) | 2006-08-25 | 2007-08-24 | Recombinant hcv e2 glycoprotein |
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| CA2661814A1 true CA2661814A1 (en) | 2008-02-28 |
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| EP (1) | EP2061805B1 (OSRAM) |
| JP (2) | JP5674310B2 (OSRAM) |
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| CN (1) | CN101563362B (OSRAM) |
| AU (1) | AU2007288129B2 (OSRAM) |
| CA (1) | CA2661814A1 (OSRAM) |
| WO (1) | WO2008022401A1 (OSRAM) |
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| US8535686B2 (en) * | 2006-08-25 | 2013-09-17 | The Macfarlane Burnet Institute For Medical Research And Public Health Limited | Recombinant HCV E2 glycoprotein |
| WO2009131681A2 (en) * | 2008-04-22 | 2009-10-29 | Rutgers, The State University | Hcv e2 construct compositions and methods |
| US9758794B2 (en) | 2008-04-22 | 2017-09-12 | Rutgers, The State University Of New Jersey | HCV E2 construct compositions and methods |
| CA2726914A1 (en) * | 2008-06-03 | 2009-12-10 | Okairos Ag | A vaccine for the prevention and therapy of hcv infections |
| CA2658714A1 (en) | 2009-03-17 | 2010-09-17 | Thomas Krey | Hcv-derived polypeptides and uses thereof |
| CN102199613A (zh) | 2010-03-25 | 2011-09-28 | 国立大学法人东京大学 | 感染性丙型肝炎病毒高生产hcv突变体及其应用 |
| AU2011286168B2 (en) | 2010-08-04 | 2015-05-28 | The Macfarlane Burnet Institute For Medical Research And Public Health Ltd | Modified hepatitis C virus proteins |
| JP5897024B2 (ja) * | 2010-11-26 | 2016-03-30 | ザ マクファーレーン バーネット インスティテュート フォー メディカル リサーチ アンド パブリック ヘルス リミテッドＴｈｅ Ｍａｃｆａｒｌａｎｅ Ｂｕｒｎｅｔ Ｉｎｓｔｉｔｕｔｅ ｆｏｒ Ｍｅｄｉｃａｌ Ｒｅｓｅａｒｃｈ ａｎｄ Ｐｕｂｌｉｃ Ｈｅａｌｔｈ Ｌｔｄ | 組成物および方法 |
| WO2013033319A2 (en) * | 2011-08-30 | 2013-03-07 | The Board Of Trustees Of The Leland Stanford Junior University | A cluster of neutralizing antibodies to hepatitis c virus |
| CN103102394B (zh) * | 2013-02-27 | 2014-06-25 | 北京大学人民医院 | 丙型肝炎病毒b细胞表位肽puhi49及其应用 |
| KR20190078574A (ko) | 2016-09-29 | 2019-07-04 | 더 맥파레인 버넷 인스티튜트 포 메디칼 리서치 앤드 퍼블릭 헬스 리미티드 | 조립된 당단백질 |
| EP4003513A4 (en) * | 2019-07-26 | 2023-08-30 | The Scripps Research Institute | MODIFIED HCV E2 IMMUNOGENS AND ASSOCIATED VACCINE COMPOSITIONS |
| BR112022023101A2 (pt) * | 2020-05-11 | 2023-01-17 | Macfarlane Burnet Institute For Medical Res And Public Health Limited | Composição compreendendo uma molécula de ácido nucleico que codifica um polipeptídeo e2 excluído de domínio variável de hcv para uso no tratamento ou prevenção de infecção por hcv, uso de uma molécula de ácido nucleico que codifica um polipeptídeo e2 excluído de domínio variável de hcv, e método de tratamento ou prevenção de infecção por hcv |
| CN112730851B (zh) * | 2021-03-31 | 2021-06-22 | 南京立顶医疗科技有限公司 | 一种高灵敏SARS-CoV-2中和抗体的检测方法、检测试剂盒 |
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| AU702436B2 (en) * | 1994-10-21 | 1999-02-18 | Innogenetics N.V. | New sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents |
| JP2002528140A (ja) * | 1998-11-05 | 2002-09-03 | ザ ボード オブ トラスティーズ オブ リーランド スタンフォード ジュニア ユニバーシティ | ヒトｐａｎ−ｈｃｖヒトモノクローナル抗体 |
| AU7602800A (en) | 1999-09-23 | 2001-04-24 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Hepatitis c virus envelope two protein (e2) which lacks all or part of the hypervariable region one (hvr1), corresponding nucleic acids, chimeric viruses and uses thereof |
| AU2001292667A1 (en) | 2000-09-13 | 2002-03-26 | Hawaii Biotechnology Group, Inc. | Immunogenic composition of hepatitis c and methods of use thereof |
| AR035869A1 (es) * | 2001-04-24 | 2004-07-21 | Innogenetics Nv | Proteinas de la envoltura de hcv glicosiladas en la estructura central, un metodo para producir la proteina de envoltura de hcv aislada, una composicion que la comprende, metodo para detectar la presencia de anticuerpos anti-hcv en una muestra, un kit de diagnostico para detectar la presencia de ant |
| IL145440A0 (en) * | 2001-09-13 | 2002-06-30 | Xtl Biopharmaceuticals Ltd | Synthetic hcv envelope proteins and their use for vaccination |
| US7473773B2 (en) * | 2004-01-07 | 2009-01-06 | Third Wave Technologies, Inc. | Determination of hepatitis C virus genotype |
| US8535686B2 (en) * | 2006-08-25 | 2013-09-17 | The Macfarlane Burnet Institute For Medical Research And Public Health Limited | Recombinant HCV E2 glycoprotein |
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Also Published As
| Publication number | Publication date |
|---|---|
| US8535686B2 (en) | 2013-09-17 |
| JP2010501594A (ja) | 2010-01-21 |
| WO2008022401A1 (en) | 2008-02-28 |
| JP5674310B2 (ja) | 2015-02-25 |
| EP2061805A4 (en) | 2010-08-04 |
| US9598467B2 (en) | 2017-03-21 |
| EP2061805B1 (en) | 2020-02-12 |
| JP2014240427A (ja) | 2014-12-25 |
| KR20090053930A (ko) | 2009-05-28 |
| CN101563362B (zh) | 2015-02-11 |
| US20140120127A1 (en) | 2014-05-01 |
| US20110014209A1 (en) | 2011-01-20 |
| AU2007288129B2 (en) | 2013-03-07 |
| JP5999524B2 (ja) | 2016-09-28 |
| EP2061805A1 (en) | 2009-05-27 |
| CN101563362A (zh) | 2009-10-21 |
| KR101500017B1 (ko) | 2015-03-09 |
| AU2007288129A1 (en) | 2008-02-28 |
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