JP2010500375A - 活性剤の多段階送達 - Google Patents

活性剤の多段階送達 Download PDF

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Publication number
JP2010500375A
JP2010500375A JP2009523983A JP2009523983A JP2010500375A JP 2010500375 A JP2010500375 A JP 2010500375A JP 2009523983 A JP2009523983 A JP 2009523983A JP 2009523983 A JP2009523983 A JP 2009523983A JP 2010500375 A JP2010500375 A JP 2010500375A
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stage
particles
particle
composition
stage particle
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JP2009523983A
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Japanese (ja)
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JP2010500375A5 (enExample
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フェラーリ，マウロ
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University of Texas System
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University of Texas System
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Publication of JP2010500375A publication Critical patent/JP2010500375A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2009523983A 2006-08-08 2007-08-08 活性剤の多段階送達 Pending JP2010500375A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82175006P 2006-08-08 2006-08-08
US91434807P 2007-04-27 2007-04-27
PCT/US2007/075516 WO2008021908A2 (en) 2006-08-08 2007-08-08 Multistage delivery of active agents

Publications (2)

Publication Number Publication Date
JP2010500375A true JP2010500375A (ja) 2010-01-07
JP2010500375A5 JP2010500375A5 (enExample) 2010-09-24

Family

ID=39082940

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009523983A Pending JP2010500375A (ja) 2006-08-08 2007-08-08 活性剤の多段階送達

Country Status (8)

Country Link
US (4) US20080311182A1 (enExample)
EP (1) EP2056794A4 (enExample)
JP (1) JP2010500375A (enExample)
CN (1) CN101652126B (enExample)
AU (1) AU2007286203B2 (enExample)
CA (1) CA2664919A1 (enExample)
MX (1) MX2009001461A (enExample)
WO (1) WO2008021908A2 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013537540A (ja) * 2010-08-16 2013-10-03 オーストラリアン ニュークリア サイエンス アンド テクノロジー オーガニゼーション 生体分子を送達するためのセラミック粒子を含む粒子状物質
JP2015536319A (ja) * 2012-10-16 2015-12-21 ウィリアム・マーシュ・ライス・ユニバーシティ 薬剤耐性を克服するための改善されたナノベクターベースの薬物送達システム
JP2018519347A (ja) * 2015-07-09 2018-07-19 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 融合性リポソーム被覆多孔質ケイ素ナノ粒子
JP2019510085A (ja) * 2016-03-08 2019-04-11 ロス ガトス ファーマスーティカルズ， インク．Ｌｏｓ Ｇａｔｏｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 癌治療のためのナノ粒子ならびに方法および化合物
JP2020504177A (ja) * 2017-01-04 2020-02-06 ナノティックス，エルエルシー 捕捉粒子をアセンブルするための方法

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US7854944B2 (en) * 2004-12-17 2010-12-21 Advanced Cardiovascular Systems, Inc. Tissue regeneration
AU2007348315A1 (en) 2006-04-07 2008-09-12 Chimeros, Inc. Compositions and methods for treating B- cell malignancies
US8563022B2 (en) * 2006-10-11 2013-10-22 Board Of Regents Of The University Of Texas System Particles for cell targeting
WO2008106350A1 (en) * 2007-02-26 2008-09-04 Board Of Regents Of The University Of Texas System Endocytotic particles
US8920625B2 (en) * 2007-04-27 2014-12-30 Board Of Regents Of The University Of Texas System Electrochemical method of making porous particles using a constant current density
AU2009238607B2 (en) * 2008-04-25 2015-08-06 Northwestern University Nanostructures suitable for sequestering cholesterol
US8173115B2 (en) 2008-07-29 2012-05-08 The Board Of Regents Of The University Of Texas System Particle compositions with a pre-selected cell internalization mode
CA2732252A1 (en) * 2008-07-29 2010-02-04 Paolo Decuzzi Particle compositions with a pre-selected cell internalization mode
WO2010025322A2 (en) * 2008-08-28 2010-03-04 The Florida International University Board Of Trustees Magnetic nanodelivery of therapeutic agents across the blood brain barrier
CA2747318A1 (en) * 2008-12-23 2010-07-01 Mauro Ferrari Inflammation targeting particles
US20100233270A1 (en) 2009-01-08 2010-09-16 Northwestern University Delivery of Oligonucleotide-Functionalized Nanoparticles
EP2376064A4 (en) * 2009-01-15 2013-08-21 Univ Texas POROUS STRUCTURES WITH MODIFIED ORGANIC BIOLOGICAL DERIVATION
JP5960434B2 (ja) * 2009-02-18 2016-08-02 アラダイム コーポレーション 肺送達のためのｐＨ調節された製剤
US8808733B2 (en) 2009-03-31 2014-08-19 The Board Of Trustees Of The University Of Arkansas Method of controlled drug release from a liposome carrier
WO2010120874A2 (en) 2009-04-14 2010-10-21 Chimeros, Inc. Chimeric therapeutics, compositions, and methods for using same
JP2012526130A (ja) * 2009-05-05 2012-10-25 アルテルムネ テクフノロジエス，エルエルシー 化学的にプログラム可能な免疫
FR2948024B1 (fr) * 2009-07-17 2020-01-10 Centre National De La Recherche Scientifique - Cnrs - Emulsion activable par ultrasons et son procede de fabrication.
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AU2011207563B2 (en) 2010-01-19 2016-03-10 Northwestern University Synthetic nanostructures including nucleic acids and/or other entities
EP2540311A4 (en) * 2010-02-26 2016-07-06 Univ Nagasaki COMPOSITE BODY FOR THE ADMINISTRATION OF ANTIGENES OR MEDICINES
CN103081107B (zh) 2010-03-09 2017-02-08 得克萨斯州大学系统董事会 多孔和非多孔纳米结构
EP2547329A4 (en) * 2010-03-17 2014-06-25 Univ Texas THEROSTATIC DELIVERY SYSTEMS WITH MODIFIED SURFACES
EP2590605A1 (en) 2010-07-09 2013-05-15 Board of Regents of the University of Texas System Biodegradable scaffolds
US20130224282A1 (en) * 2010-09-21 2013-08-29 Massachusetts Institute Of Technology Multistage Nanoparticles
RU2475233C2 (ru) * 2010-12-01 2013-02-20 Учреждение Российской академии наук Институт кристаллографии им. А.В. Шубникова РАН Фармакологическая композиция, предназначенная для интраназального введения с целью доставки в мозг фармакологически активного компонента, и способ ее получения
US9089498B2 (en) * 2011-04-14 2015-07-28 The Regents Of The University Of California Multifunctional nanoparticle designs and applications
US9541480B2 (en) 2011-06-29 2017-01-10 Academia Sinica Capture, purification, and release of biological substances using a surface coating
US9101547B2 (en) 2011-08-04 2015-08-11 Nano And Advanced Materials Institute Limited Enteric-coated capsule containing cationic nanoparticles for oral insulin delivery
US8859004B2 (en) 2011-08-04 2014-10-14 Nano And Advanced Materials Institute Limited pH-sensitive nanoparticles for oral insulin delivery
JP2014527072A (ja) 2011-09-09 2014-10-09 バイオメド リアルティー， エル．ピー． ウイルスタンパク質の集合を制御するための方法および組成物
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WO2013070872A1 (en) 2011-11-08 2013-05-16 The Board Of Trustees Of The University Of Arkansas Methods and compositions for x-ray induced release from ph sensitive liposomes
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US10842749B2 (en) * 2012-06-12 2020-11-24 The Methodist Hospital Research Institute Compositions and methods of treating therapy resistant cancer and uses thereof
US8883216B2 (en) * 2012-08-27 2014-11-11 Red Lion Chem Tech, Llc Methods and ceramic nanoparticle compositions for heavy metal removal and for oral delivery of desirable agents
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JP2015007209A (ja) * 2013-05-31 2015-01-15 株式会社リコー コアシェル型粒子、及びその製造方法
WO2015013673A1 (en) 2013-07-25 2015-01-29 Aurasense Therapeutics, Llc Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
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JP6741673B2 (ja) 2014-10-06 2020-08-19 イグジキュア, インコーポレーテッドExicure, Inc. 抗ｔｎｆ化合物
JP2017537619A (ja) 2014-11-21 2017-12-21 ノースウェスタン ユニバーシティ 球状核酸ナノ粒子複合体の配列特異的細胞内取込
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JP6865491B2 (ja) * 2017-07-25 2021-04-28 レモネックス インコーポレイテッドＬｅｍｏｎｅｘ Ｉｎｃ． 血管内生理活性物質送達用組成物
KR102152348B1 (ko) 2017-09-05 2020-09-08 주식회사 레모넥스 세포 운명 조절용 조성물
HUE068741T2 (hu) 2017-12-19 2025-01-28 Nanobiotix Nanorészecskék idegi zavarok kezelésére
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013537540A (ja) * 2010-08-16 2013-10-03 オーストラリアン ニュークリア サイエンス アンド テクノロジー オーガニゼーション 生体分子を送達するためのセラミック粒子を含む粒子状物質
JP2015536319A (ja) * 2012-10-16 2015-12-21 ウィリアム・マーシュ・ライス・ユニバーシティ 薬剤耐性を克服するための改善されたナノベクターベースの薬物送達システム
JP2018519347A (ja) * 2015-07-09 2018-07-19 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 融合性リポソーム被覆多孔質ケイ素ナノ粒子
JP2019510085A (ja) * 2016-03-08 2019-04-11 ロス ガトス ファーマスーティカルズ， インク．Ｌｏｓ Ｇａｔｏｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 癌治療のためのナノ粒子ならびに方法および化合物
JP2020504177A (ja) * 2017-01-04 2020-02-06 ナノティックス，エルエルシー 捕捉粒子をアセンブルするための方法
JP2023075293A (ja) * 2017-01-04 2023-05-30 ナノティックス，エルエルシー 捕捉粒子をアセンブルするための方法

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Publication number Publication date
AU2007286203A2 (en) 2009-03-19
CN101652126B (zh) 2013-07-17
EP2056794A2 (en) 2009-05-13
AU2007286203A1 (en) 2008-02-21
AU2007286203B2 (en) 2013-05-02
WO2008021908A2 (en) 2008-02-21
CN101652126A (zh) 2010-02-17
US20160051481A1 (en) 2016-02-25
US20190111000A1 (en) 2019-04-18
US20080311182A1 (en) 2008-12-18
WO2008021908A3 (en) 2008-08-14
HK1140139A1 (zh) 2010-10-08
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