JP2010112955A5 - - Google Patents

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Publication number
JP2010112955A5
JP2010112955A5 JP2009267007A JP2009267007A JP2010112955A5 JP 2010112955 A5 JP2010112955 A5 JP 2010112955A5 JP 2009267007 A JP2009267007 A JP 2009267007A JP 2009267007 A JP2009267007 A JP 2009267007A JP 2010112955 A5 JP2010112955 A5 JP 2010112955A5
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JP
Japan
Prior art keywords
receptor
cell
protein
cells
group
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JP2009267007A
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English (en)
Japanese (ja)
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JP5187910B2 (ja
JP2010112955A (ja
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Publication of JP2010112955A publication Critical patent/JP2010112955A/ja
Publication of JP2010112955A5 publication Critical patent/JP2010112955A5/ja
Application granted granted Critical
Publication of JP5187910B2 publication Critical patent/JP5187910B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2009267007A 2002-04-12 2009-11-25 膜貫通型タンパク質と相互作用する化合物の同定法 Expired - Lifetime JP5187910B2 (ja)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US37170402P 2002-04-12 2002-04-12
US60/371,704 2002-04-12
US37941902P 2002-05-13 2002-05-13
US60/379,419 2002-05-13
US38757002P 2002-06-12 2002-06-12
US60/387,570 2002-06-12
US42289102P 2002-11-01 2002-11-01
US60/422,891 2002-11-01
US44255603P 2003-01-27 2003-01-27
US60/442,556 2003-01-27

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2003584728A Division JP4542342B2 (ja) 2002-04-12 2003-04-11 膜貫通型タンパク質と相互作用する化合物の同定法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012273726A Division JP5870016B2 (ja) 2002-04-12 2012-12-14 膜貫通型タンパク質と相互作用する化合物の同定法

Publications (3)

Publication Number Publication Date
JP2010112955A JP2010112955A (ja) 2010-05-20
JP2010112955A5 true JP2010112955A5 (enExample) 2011-08-18
JP5187910B2 JP5187910B2 (ja) 2013-04-24

Family

ID=29255685

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2003584728A Expired - Lifetime JP4542342B2 (ja) 2002-04-12 2003-04-11 膜貫通型タンパク質と相互作用する化合物の同定法
JP2009267007A Expired - Lifetime JP5187910B2 (ja) 2002-04-12 2009-11-25 膜貫通型タンパク質と相互作用する化合物の同定法
JP2012273726A Expired - Lifetime JP5870016B2 (ja) 2002-04-12 2012-12-14 膜貫通型タンパク質と相互作用する化合物の同定法
JP2015190891A Expired - Lifetime JP6168669B2 (ja) 2002-04-12 2015-09-29 膜貫通型タンパク質と相互作用する化合物の同定法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2003584728A Expired - Lifetime JP4542342B2 (ja) 2002-04-12 2003-04-11 膜貫通型タンパク質と相互作用する化合物の同定法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2012273726A Expired - Lifetime JP5870016B2 (ja) 2002-04-12 2012-12-14 膜貫通型タンパク質と相互作用する化合物の同定法
JP2015190891A Expired - Lifetime JP6168669B2 (ja) 2002-04-12 2015-09-29 膜貫通型タンパク質と相互作用する化合物の同定法

Country Status (16)

Country Link
US (8) US7309576B2 (enExample)
EP (3) EP2339347A1 (enExample)
JP (4) JP4542342B2 (enExample)
CN (1) CN100399028C (enExample)
AT (1) ATE421697T1 (enExample)
AU (2) AU2003218586B2 (enExample)
CA (1) CA2521946C (enExample)
CY (1) CY1108997T1 (enExample)
DE (1) DE60325953D1 (enExample)
DK (1) DK1495330T3 (enExample)
ES (2) ES2321704T3 (enExample)
MX (1) MXPA04011134A (enExample)
NZ (2) NZ567458A (enExample)
PT (1) PT1495330E (enExample)
SI (1) SI1495330T1 (enExample)
WO (1) WO2003087836A1 (enExample)

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DK1495330T3 (da) * 2002-04-12 2009-05-18 Brian F O'dowd Fremgangsmåde til at identificere forbindelser, som påvirker transmembran-proteiner
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CN1944647B (zh) * 2006-08-23 2010-05-12 华东师范大学 多巴胺受体新亚型d5b基因及编码的蛋白与应用
JP4929462B2 (ja) 2007-01-29 2012-05-09 国立大学法人高知大学 細胞膜上分子と相互作用する化合物の検出方法
WO2008156655A2 (en) 2007-06-15 2008-12-24 Genelux Corporation Vaccinia virus vectors encoding a sodium-dependent transporter protein for imaging and/or treatment of tumors
JP5230397B2 (ja) * 2008-12-18 2013-07-10 独立行政法人科学技術振興機構 抗膜貫通型タンパク質抗体の抗原結合部位を決定する方法
CN102580091B (zh) * 2011-01-12 2014-12-10 中国科学院上海生命科学研究院 增强阿片镇痛剂的镇痛作用的方法及试剂
US8643360B1 (en) * 2012-09-02 2014-02-04 George S. Cargill, III In-water voltage gradient detector
TWI472617B (zh) * 2012-09-17 2015-02-11 Nat Univ Chung Hsing 調控大分子進入細胞內之蛋白質及其調控大分子進入細胞內之方法
US10513711B2 (en) 2014-08-13 2019-12-24 Dupont Us Holding, Llc Genetic targeting in non-conventional yeast using an RNA-guided endonuclease
WO2016073433A1 (en) 2014-11-06 2016-05-12 E. I. Du Pont De Nemours And Company Peptide-mediated delivery of rna-guided endonuclease into cells
BR112017024534A2 (pt) 2015-05-15 2018-07-24 Pioneer Hi Bred Int sistemas de rna-guia/endonuclease cas9 inovadores
EP4144844B1 (en) 2015-10-12 2025-09-10 DuPont US Holding, LLC Protected dna templates for gene modification and increased homologous recombination in cells and methods of use
US20180282763A1 (en) 2015-10-20 2018-10-04 Pioneer Hi-Bred International, Inc. Restoring function to a non-functional gene product via guided cas systems and methods of use
US20180258438A1 (en) 2015-11-06 2018-09-13 Pioneer Hi-Bred International, Inc. Generation of complex trait loci in soybean and methods of use
WO2017100158A1 (en) 2015-12-11 2017-06-15 Danisco Us Inc. Methods and compositions for enhanced nuclease-mediated genome modification and reduced off-target site effects
EP3390631B1 (en) 2015-12-18 2020-04-08 Danisco US Inc. Methods and compositions for t-rna based guide rna expression
BR112018015348A2 (pt) 2016-01-26 2018-12-18 Pioneer Hi Bred Int método para obter uma planta de milho ceroso, planta, semente, polinucleotídeo-guia e método para produzir uma planta híbrida de milho ceroso
EP3699281A1 (en) 2016-03-11 2020-08-26 Pioneer Hi-Bred International, Inc. Novel cas9 systems and methods of use
WO2017155717A1 (en) 2016-03-11 2017-09-14 Pioneer Hi-Bred International, Inc. Novel cas9 systems and methods of use
WO2017155715A1 (en) 2016-03-11 2017-09-14 Pioneer Hi-Bred International, Inc. Novel cas9 systems and methods of use
KR20190016970A (ko) 2016-06-14 2019-02-19 파이어니어 하이 부렛드 인터내쇼날 인코포레이팃드 식물 게놈 변형을 위한 cpf1 엔도뉴클레아제의 용도
WO2017222773A1 (en) 2016-06-20 2017-12-28 Pioneer Hi-Bred International, Inc. Novel cas systems and methods of use
EP3525578A1 (en) 2016-10-13 2019-08-21 Pioneer Hi-Bred International, Inc. Generating northern leaf blight resistant maize
US11473081B2 (en) 2016-12-12 2022-10-18 xCella Biosciences, Inc. Methods and systems for screening using microcapillary arrays
CA3048904A1 (en) 2016-12-30 2018-07-05 xCella Biosciences, Inc. Multi-stage sample recovery system
WO2018129440A1 (en) 2017-01-09 2018-07-12 University Of Massachusetts Complexes for gene deletion and editing
EP3707253A1 (en) 2017-12-15 2020-09-16 Danisco US Inc. Cas9 variants and methods of use
CN108178790B (zh) * 2018-01-18 2021-09-07 上海药明康德新药开发有限公司 一种将细胞膜分离以便对跨膜蛋白进行dna编码化合物库筛选的方法
WO2019165168A1 (en) 2018-02-23 2019-08-29 Pioneer Hi-Bred International, Inc. Novel cas9 orthologs
EP3866583A1 (en) 2018-10-16 2021-08-25 Pioneer Hi-Bred International, Inc. Genome edited fine mapping and causal gene identification
EP4371930B1 (en) 2018-12-06 2025-08-20 Xcella Biosciences, Inc. Lateral loading of microcapillary arrays
US12365888B2 (en) 2018-12-14 2025-07-22 Pioneer Hi-Bred International, Inc. CRISPR-Cas systems for genome editing
JOP20210164A1 (ar) 2019-01-11 2023-01-30 Omeros Corp طرق وتركيبات علاج السرطان
EP3947656A1 (en) 2019-04-05 2022-02-09 Danisco US Inc. Methods for polynucleotide integration into the genome of bacillus using dual circular recombinant dna constructs and compositions thereof
CA3136114A1 (en) 2019-04-05 2020-10-08 Danisco Us Inc. Methods for integrating a donor dna sequence into the genome of bacillus using linear recombinant dna constructs and compositions thereof
KR102329302B1 (ko) * 2019-09-30 2021-11-22 한국과학기술연구원 도파민 d1형 수용체의 활성 측정용 적색 형광 단백질 기반 바이오센서
WO2023105244A1 (en) 2021-12-10 2023-06-15 Pig Improvement Company Uk Limited Editing tmprss2/4 for disease resistance in livestock
KR102833970B1 (ko) * 2022-02-23 2025-07-17 충남대학교산학협력단 핵수송 신호 펩타이드가 접합된 핵산 전달용 2세대 폴리아미도아민 덴드리머 고분자 유도체
WO2024013514A2 (en) 2022-07-15 2024-01-18 Pig Improvement Company Uk Limited Gene edited livestock animals having coronavirus resistance
WO2024118881A1 (en) 2022-12-01 2024-06-06 Genencor International Bv Iterative muliplex genome engineering in microbial cells using a bidirectional selection marker system
EP4627076A1 (en) 2022-12-01 2025-10-08 Danisco Us Inc Iterative multiplex genome engineering in microbial cells using a recombinant self-excisable selection marker system
WO2024118882A1 (en) 2022-12-01 2024-06-06 Genencor International Bv Iterative multiplex genome engineering in microbial cells using a selection marker swapping system
AU2024239266A1 (en) 2023-03-20 2025-09-25 Pioneer Hi-Bred International, Inc. Cas polypeptides with altered pam recognition

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US20030022277A1 (en) * 1995-05-05 2003-01-30 Daniel R. Soppet Human neuropeptide receptor
US6004808A (en) * 1996-06-21 1999-12-21 Aurora Biosciences Corporation Promiscuous G-protein compositions and their use
US5891646A (en) 1997-06-05 1999-04-06 Duke University Methods of assaying receptor activity and constructs useful in such methods
US6383761B2 (en) * 1997-07-28 2002-05-07 The Regents Of The University Of California Methods and compositions for identifying modulators of G-protein-coupled receptors
CA2399593A1 (en) * 2000-02-09 2001-08-16 Human Genome Sciences, Inc. Antibodies to ccr5
AU2001284974A1 (en) 2000-08-16 2002-02-25 The Trustees Of Columbia University In The City Of New York Quantitative assessment of erbb/her receptors in biological fluids
DK1495330T3 (da) 2002-04-12 2009-05-18 Brian F O'dowd Fremgangsmåde til at identificere forbindelser, som påvirker transmembran-proteiner

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