JP2009544698A5 - - Google Patents
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- Publication number
- JP2009544698A5 JP2009544698A5 JP2009521759A JP2009521759A JP2009544698A5 JP 2009544698 A5 JP2009544698 A5 JP 2009544698A5 JP 2009521759 A JP2009521759 A JP 2009521759A JP 2009521759 A JP2009521759 A JP 2009521759A JP 2009544698 A5 JP2009544698 A5 JP 2009544698A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- polynucleotide
- viral vector
- vector
- coronary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091033319 polynucleotide Proteins 0.000 claims 11
- 102000040430 polynucleotide Human genes 0.000 claims 11
- 239000002157 polynucleotide Substances 0.000 claims 11
- 239000013603 viral vector Substances 0.000 claims 7
- 210000004204 blood vessel Anatomy 0.000 claims 5
- 230000004087 circulation Effects 0.000 claims 3
- 210000004351 coronary vessel Anatomy 0.000 claims 3
- 210000002064 heart cell Anatomy 0.000 claims 3
- 210000003140 lateral ventricle Anatomy 0.000 claims 3
- 241000702423 Adeno-associated virus - 2 Species 0.000 claims 2
- 108090000565 Capsid Proteins Proteins 0.000 claims 2
- 102100023321 Ceruloplasmin Human genes 0.000 claims 2
- 108091026890 Coding region Proteins 0.000 claims 2
- 208000019622 heart disease Diseases 0.000 claims 2
- 238000001802 infusion Methods 0.000 claims 2
- 238000002347 injection Methods 0.000 claims 2
- 239000007924 injection Substances 0.000 claims 2
- 238000004904 shortening Methods 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 238000001890 transfection Methods 0.000 claims 2
- 239000013598 vector Substances 0.000 claims 2
- 241000972680 Adeno-associated virus - 6 Species 0.000 claims 1
- 206010007559 Cardiac failure congestive Diseases 0.000 claims 1
- 102000016911 Deoxyribonucleases Human genes 0.000 claims 1
- 108010053770 Deoxyribonucleases Proteins 0.000 claims 1
- 241000702421 Dependoparvovirus Species 0.000 claims 1
- 206010019280 Heart failures Diseases 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 210000005241 right ventricle Anatomy 0.000 claims 1
- 230000001839 systemic circulation Effects 0.000 claims 1
- 230000002861 ventricular Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83332406P | 2006-07-25 | 2006-07-25 | |
| US60/833,324 | 2006-07-25 | ||
| PCT/US2007/016129 WO2008013692A2 (en) | 2006-07-25 | 2007-07-16 | Extended antegrade epicardial coronary infusion of adeno-associated viral vectors for gene therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014156560A Division JP2014218509A (ja) | 2006-07-25 | 2014-07-31 | 遺伝子治療用アデノ随伴ウイルスベクターの長期順行性の心外膜冠動脈注入 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009544698A JP2009544698A (ja) | 2009-12-17 |
| JP2009544698A5 true JP2009544698A5 (https=) | 2010-09-02 |
| JP5623740B2 JP5623740B2 (ja) | 2014-11-12 |
Family
ID=38581949
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009521759A Active JP5623740B2 (ja) | 2006-07-25 | 2007-07-16 | 遺伝子治療用アデノ随伴ウイルスベクターの長期順行性の心外膜冠動脈注入 |
| JP2014156560A Pending JP2014218509A (ja) | 2006-07-25 | 2014-07-31 | 遺伝子治療用アデノ随伴ウイルスベクターの長期順行性の心外膜冠動脈注入 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014156560A Pending JP2014218509A (ja) | 2006-07-25 | 2014-07-31 | 遺伝子治療用アデノ随伴ウイルスベクターの長期順行性の心外膜冠動脈注入 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20080076730A1 (https=) |
| EP (2) | EP2460879A1 (https=) |
| JP (2) | JP5623740B2 (https=) |
| KR (1) | KR20090035711A (https=) |
| CN (1) | CN101495627A (https=) |
| AU (1) | AU2007277392A1 (https=) |
| CA (1) | CA2658628A1 (https=) |
| DK (1) | DK2044199T3 (https=) |
| ES (1) | ES2398593T3 (https=) |
| GB (1) | GB2437893A (https=) |
| IL (1) | IL196541A (https=) |
| PL (1) | PL2044199T3 (https=) |
| WO (1) | WO2008013692A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009105135A1 (en) | 2008-02-19 | 2009-08-27 | Celladon Corporation | Compositions for enhanced uptake of viral vectors in the myocardium |
| PH12012501579A1 (en) * | 2010-01-05 | 2012-10-22 | Michael Aaron | Vertical axis variable geometry wind energy collection system |
| US11583662B2 (en) | 2016-04-18 | 2023-02-21 | Sardocor Corp. | Methods and compositions for consistent intracoronary administration of a biologic |
| KR20190139951A (ko) * | 2017-04-14 | 2019-12-18 | 리젠엑스바이오 인크. | 인간 뉴런 또는 신경교 세포에 의해 생성된 재조합 인간 이두로네이트-2 설파타제(ids)를 이용한 뮤코다당증 ii형의 치료 |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| US5672344A (en) | 1987-12-30 | 1997-09-30 | The Regents Of The University Of Michigan | Viral-mediated gene transfer system |
| US5302523A (en) | 1989-06-21 | 1994-04-12 | Zeneca Limited | Transformation of plant cells |
| US5587308A (en) * | 1992-06-02 | 1996-12-24 | The United States Of America As Represented By The Department Of Health & Human Services | Modified adeno-associated virus vector capable of expression from a novel promoter |
| US6268213B1 (en) * | 1992-06-03 | 2001-07-31 | Richard Jude Samulski | Adeno-associated virus vector and cis-acting regulatory and promoter elements capable of expressing at least one gene and method of using same for gene therapy |
| US5478745A (en) * | 1992-12-04 | 1995-12-26 | University Of Pittsburgh | Recombinant viral vector system |
| US5658785A (en) * | 1994-06-06 | 1997-08-19 | Children's Hospital, Inc. | Adeno-associated virus materials and methods |
| US6613749B1 (en) | 1994-07-26 | 2003-09-02 | Imperial College Innovations Limited | Papovavirus pseudocapsids and use thereof for exogenous material transfer |
| WO2001034208A1 (en) * | 1999-11-05 | 2001-05-17 | The Regents Of The University Of California | Techniques and compositions for treating cardiovascular disease by in vivo gene delivery |
| US7745416B2 (en) * | 1995-04-11 | 2010-06-29 | The Regents Of The University Of California | Method for in vivo regulation of cardiac muscle contractility |
| US5773289A (en) * | 1995-06-06 | 1998-06-30 | University Of Pittsburgh | AAV directed targeted integration |
| US6001650A (en) | 1995-08-03 | 1999-12-14 | Avigen, Inc. | High-efficiency wild-type-free AAV helper functions |
| US6162796A (en) * | 1995-09-27 | 2000-12-19 | The Rockefeller University | Method for transferring genes to the heart using AAV vectors |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| DE69608122T3 (de) | 1995-11-09 | 2011-06-16 | Microbiological Research Authority Camr, Salisbury | Mikroverkapselte dna zur impfung und gentherapie |
| US20020001574A1 (en) | 1995-12-13 | 2002-01-03 | Jon A. Woiff | Process of delivering a polynucleotide to a muscle cell via the vascular system |
| US5858351A (en) * | 1996-01-18 | 1999-01-12 | Avigen, Inc. | Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors |
| US5962313A (en) * | 1996-01-18 | 1999-10-05 | Avigen, Inc. | Adeno-associated virus vectors comprising a gene encoding a lyosomal enzyme |
| US5846528A (en) * | 1996-01-18 | 1998-12-08 | Avigen, Inc. | Treating anemia using recombinant adeno-associated virus virions comprising an EPO DNA sequence |
| US20090239940A1 (en) * | 1997-07-22 | 2009-09-24 | Del Monte Federica | Treating heart failure and ventricular arrhythmias |
| US20050095227A1 (en) * | 1997-07-22 | 2005-05-05 | The General Hospital Corporation | Treating heart failure |
| US6566118B1 (en) * | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| US6410300B1 (en) * | 1998-01-12 | 2002-06-25 | The University Of North Carolina At Chapel Hill | Methods and formulations for mediating adeno-associated virus (AAV) attachment and infection and methods for purifying AAV |
| JP2002502885A (ja) * | 1998-02-11 | 2002-01-29 | ザ・リージェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア | 増強された遺伝子送達のための、核酸および血管作用性薬剤の組合せ |
| US6958147B1 (en) * | 1998-10-26 | 2005-10-25 | Licentia Ltd | Use of VEGF-C to prevent restenosis |
| US6759237B1 (en) * | 1998-11-05 | 2004-07-06 | The Trustees Of The University Of Pennsylvania | Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same |
| EP1139751A4 (en) * | 1998-12-28 | 2003-03-19 | Arch Dev Corp | EFFICIENT AND STABLE -I (IN VIVO) GENE TRANSFER TO CARDIOMYCETS USING RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS |
| US6258595B1 (en) | 1999-03-18 | 2001-07-10 | The Trustees Of The University Of Pennsylvania | Compositions and methods for helper-free production of recombinant adeno-associated viruses |
| CA2373110A1 (en) * | 2000-03-14 | 2001-09-20 | Neurologix, Inc. | Production of chimeric capsid vectors |
| WO2001096587A2 (en) * | 2000-06-13 | 2001-12-20 | The Children's Hospital Of Philadelphia | Methods for administering recombinant adeno-associated virus virions to humans previously exposed to adeno-associated virus |
| WO2002019966A2 (en) * | 2000-09-06 | 2002-03-14 | Johns Hopkins University | Cardiac arrhythmia treatment methods |
| ATE423574T1 (de) * | 2000-09-11 | 2009-03-15 | Univ California | Dominant-negativer plb mutant zur behandlung der herzerkrankungen |
| MX359371B (es) * | 2001-11-13 | 2018-09-25 | Univ Pennsylvania | Un metodo para detectar y/o identificar secuencias del virus adeno-asociado y aislamiento de secuencias novedosas identificadas de ese modo. |
| US20040106954A1 (en) * | 2002-11-15 | 2004-06-03 | Whitehurst Todd K. | Treatment of congestive heart failure |
| US7781415B2 (en) * | 2003-02-07 | 2010-08-24 | Roche Madison Inc. | Process for delivering sirna to cardiac muscle tissue |
| JP2009513556A (ja) * | 2003-07-17 | 2009-04-02 | バイエリッシェ ユリウス−マクシミリアンズ−ウニヴァージタット ヴュルツブルグ | 狭窄および再狭窄を阻害するための医薬品の製造におけるｆａｋ関連非キナーゼの使用 |
| WO2005023292A1 (en) * | 2003-09-03 | 2005-03-17 | The General Hospital Corporation | Methods of treating restenosis |
| EP1691609A4 (en) * | 2003-12-11 | 2006-11-29 | Mirus Bio Corp | RELEASE OF VIRUS VECTORS ANEXTRAVASAL PARENCHYM CELLS |
| US20060148742A1 (en) * | 2004-02-26 | 2006-07-06 | Kaye David M | Polynucleotide delivery to cardiac tissue |
| US7840263B2 (en) * | 2004-02-27 | 2010-11-23 | Cardiac Pacemakers, Inc. | Method and apparatus for device controlled gene expression |
| CN101056539B (zh) * | 2004-09-09 | 2012-12-12 | 综合医院公司 | 调节心脏细胞中的磷酸酶活性 |
| US9375440B2 (en) * | 2006-11-03 | 2016-06-28 | Medtronic, Inc. | Compositions and methods for making therapies delivered by viral vectors reversible for safety and allele-specificity |
| WO2009105135A1 (en) * | 2008-02-19 | 2009-08-27 | Celladon Corporation | Compositions for enhanced uptake of viral vectors in the myocardium |
-
2007
- 2007-07-16 GB GB0716413A patent/GB2437893A/en not_active Withdrawn
- 2007-07-16 CN CNA2007800283615A patent/CN101495627A/zh active Pending
- 2007-07-16 WO PCT/US2007/016129 patent/WO2008013692A2/en not_active Ceased
- 2007-07-16 JP JP2009521759A patent/JP5623740B2/ja active Active
- 2007-07-16 PL PL07810511T patent/PL2044199T3/pl unknown
- 2007-07-16 ES ES07810511T patent/ES2398593T3/es active Active
- 2007-07-16 AU AU2007277392A patent/AU2007277392A1/en not_active Abandoned
- 2007-07-16 KR KR1020097003514A patent/KR20090035711A/ko not_active Withdrawn
- 2007-07-16 EP EP12151812A patent/EP2460879A1/en not_active Withdrawn
- 2007-07-16 EP EP07810511A patent/EP2044199B1/en not_active Not-in-force
- 2007-07-16 CA CA002658628A patent/CA2658628A1/en not_active Abandoned
- 2007-07-16 DK DK07810511.1T patent/DK2044199T3/da active
- 2007-07-17 US US11/778,900 patent/US20080076730A1/en not_active Abandoned
-
2009
- 2009-01-15 IL IL196541A patent/IL196541A/en active IP Right Grant
-
2014
- 2014-07-31 JP JP2014156560A patent/JP2014218509A/ja active Pending
-
2016
- 2016-10-13 US US15/292,642 patent/US20170252462A1/en not_active Abandoned
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