JP2009544660A - 合成プローブによる融合タンパク質の標識化 - Google Patents
合成プローブによる融合タンパク質の標識化 Download PDFInfo
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
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- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
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- Enzymes And Modification Thereof (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| EP06117779A EP1882688A1 (en) | 2006-07-25 | 2006-07-25 | Labelling of fusion proteins with synthetic probes |
| PCT/EP2007/057597 WO2008012296A1 (en) | 2006-07-25 | 2007-07-24 | Labelling of fusion proteins with synthetic probes |
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| JP2009544660A true JP2009544660A (ja) | 2009-12-17 |
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| JP (1) | JP2009544660A (https=) |
| CN (1) | CN101516857A (https=) |
| WO (1) | WO2008012296A1 (https=) |
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| CA2553261C (en) | 2004-01-16 | 2014-03-18 | Stefan Barth | Immunokinases |
| WO2007006055A2 (en) | 2005-07-06 | 2007-01-11 | Vascular Pathways Inc. | Intravenous catheter insertion device and method of use |
| EP1800695A1 (en) | 2005-12-21 | 2007-06-27 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Immuno-RNA-constructs |
| JP5139518B2 (ja) | 2007-05-07 | 2013-02-06 | バスキュラー・パスウェイズ・インコーポレイテッド | 静脈カテーテル挿入装置 |
| CA2693155A1 (en) * | 2007-07-25 | 2009-01-29 | Fraunhofer Gesellschaft Zur Forderung Der Angewandten Forschung E.V. | Self coupling recombinant antibody fusion proteins |
| WO2010031767A2 (en) * | 2008-09-16 | 2010-03-25 | Technische Universität München | Fluorescent-labelled atpases |
| FR2936245B1 (fr) * | 2008-09-23 | 2012-07-06 | Cis Bio Int | Nouveaux substrats d'o6-alkylguanine-adn alkyltransferase et ses mutants. |
| US9950139B2 (en) | 2010-05-14 | 2018-04-24 | C. R. Bard, Inc. | Catheter placement device including guidewire and catheter control elements |
| US8932258B2 (en) | 2010-05-14 | 2015-01-13 | C. R. Bard, Inc. | Catheter placement device and method |
| US10384039B2 (en) | 2010-05-14 | 2019-08-20 | C. R. Bard, Inc. | Catheter insertion device including top-mounted advancement components |
| US9872971B2 (en) | 2010-05-14 | 2018-01-23 | C. R. Bard, Inc. | Guidewire extension system for a catheter placement device |
| US11925779B2 (en) | 2010-05-14 | 2024-03-12 | C. R. Bard, Inc. | Catheter insertion device including top-mounted advancement components |
| US8690833B2 (en) | 2011-01-31 | 2014-04-08 | Vascular Pathways, Inc. | Intravenous catheter and insertion device with reduced blood spatter |
| WO2012154277A1 (en) | 2011-02-25 | 2012-11-15 | C.R. Bard, Inc. | Medical component insertion device including a retractable needle |
| USD903101S1 (en) | 2011-05-13 | 2020-11-24 | C. R. Bard, Inc. | Catheter |
| EP2782916B1 (en) | 2011-11-21 | 2018-02-28 | Promega Corporation | Carboxy x rhodamine analogs |
| BR112014013745B1 (pt) * | 2011-12-09 | 2022-06-14 | Institut Pasteur | Método de teste in vitro, kit de detecção e seu uso, método in vitro de diagnóstico, método de fabricação de kit, e teste de imunosseleção multiplex |
| US9267117B2 (en) | 2012-03-15 | 2016-02-23 | New England Biolabs, Inc. | Mapping cytosine modifications |
| CA2866933C (en) | 2012-03-21 | 2020-08-18 | Rheinisch-Westfalische Technische Hochschule Aachen | Novel photoimmunoconjugates for use in photodynamic therapy |
| CN108607150B (zh) | 2013-01-30 | 2021-01-12 | 血管通路股份有限公司 | 用于静脉穿刺和导管放置的系统和方法 |
| US9782568B2 (en) | 2013-02-05 | 2017-10-10 | Vascular Pathways, Inc. | Systems and methods for needle and catheter advancement |
| WO2014152298A1 (en) | 2013-03-15 | 2014-09-25 | Promega Corporation | New silicon and germanium dyes for use in genetic identity |
| US9708658B2 (en) | 2013-03-19 | 2017-07-18 | New England Biolabs, Inc. | Enrichment of target sequences |
| WO2016003795A1 (en) | 2014-07-02 | 2016-01-07 | New England Biolabs, Inc. | Universal n-glycan binding reagent |
| WO2016037127A1 (en) | 2014-09-05 | 2016-03-10 | C.R. Bard, Inc. | Catheter insertion device including retractable needle |
| WO2016093838A1 (en) | 2014-12-11 | 2016-06-16 | New England Biolabs, Inc. | Enrichment of target sequences |
| USD903100S1 (en) | 2015-05-01 | 2020-11-24 | C. R. Bard, Inc. | Catheter placement device |
| EP3294380B1 (en) | 2015-05-15 | 2022-03-23 | C. R. Bard, Inc. | Catheter insertion device |
| CN113444046B (zh) | 2016-07-20 | 2023-10-27 | 纳莹(上海)生物科技有限公司 | 一种荧光探针及其制备方法和用途 |
| US10493262B2 (en) | 2016-09-12 | 2019-12-03 | C. R. Bard, Inc. | Blood control for a catheter insertion device |
| JP6953541B2 (ja) | 2017-03-01 | 2021-10-27 | シー・アール・バード・インコーポレーテッドＣ Ｒ Ｂａｒｄ Ｉｎｃｏｒｐｏｒａｔｅｄ | カテーテル挿入装置 |
| CN109574880B (zh) | 2017-09-29 | 2022-06-17 | 纳莹(上海)生物科技有限公司 | 一种荧光探针及其制备方法和用途 |
| US11389626B2 (en) | 2018-03-07 | 2022-07-19 | Bard Access Systems, Inc. | Guidewire advancement and blood flashback systems for a medical device insertion system |
| CN110498799B (zh) | 2018-05-18 | 2022-07-05 | 纳莹(上海)生物科技有限公司 | 一种荧光探针及其制备方法和用途 |
| USD921884S1 (en) | 2018-07-27 | 2021-06-08 | Bard Access Systems, Inc. | Catheter insertion device |
| CN111748089B (zh) * | 2019-03-28 | 2023-07-18 | 成都先导药物开发股份有限公司 | 一种生物素标记化合物以及确定化合物结合靶标蛋白的方法 |
| US11390915B2 (en) | 2019-04-26 | 2022-07-19 | New England Biolabs, Inc. | Polynucleotide adapter design for reduced bias |
| JP7721504B2 (ja) | 2019-08-19 | 2025-08-12 | ベクトン・ディキンソン・アンド・カンパニー | 正中線カテーテル配置デバイス |
| EP4025288A1 (en) | 2019-09-20 | 2022-07-13 | Bard Peripheral Vascular, Inc. | Intravenous catheter-placement device |
| WO2021183921A1 (en) | 2020-03-12 | 2021-09-16 | New England Biolabs, Inc. | A rapid diagnostic test for lamp |
| US11740240B2 (en) * | 2020-07-20 | 2023-08-29 | Bio-Rad Laboratories, Inc. | Immunoassay for SARS-CoV-2 neutralizing antibodies and materials therefor |
| EP4110945A2 (en) | 2020-08-21 | 2023-01-04 | New England Biolabs, Inc. | A rapid diagnostic test for lamp |
| WO2023197015A1 (en) | 2022-04-08 | 2023-10-12 | New England Biolabs, Inc. | Compositions and analysis of dephosphorylated oligoribonucleotides |
| CN118165544B (zh) * | 2022-12-11 | 2025-09-05 | 中国科学院大连化学物理研究所 | 适用于细胞膜动态超分辨成像的五甲川菁染料荧光探针合成与应用 |
| WO2025129193A1 (en) | 2023-12-15 | 2025-06-19 | New England Biolabs, Inc. | Glycosyltransferases and related methods |
| GB202400129D0 (en) | 2024-01-04 | 2024-02-21 | Cambridge Entpr Ltd | Nucleic acid barcodes |
| WO2025224010A1 (en) | 2024-04-24 | 2025-10-30 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. | Improved o6-alkylguanine-dna alkyltransferase substrates |
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| DE19600934A1 (de) * | 1996-01-12 | 1997-07-17 | Basf Ag | Substituierte Aza- und Diazacycloheptan- und Cyclooctanverbindungen und deren Verwendung |
| CN1420882A (zh) * | 1999-07-28 | 2003-05-28 | 阿温蒂斯药物公司 | 取代的氧代氮杂杂环基化合物 |
| CN1720332A (zh) * | 2002-10-03 | 2006-01-11 | 洛桑生态综合技术联合公司 | O6－烷基鸟嘌呤－dna烷基转移酶的底物 |
| EP1730298B1 (en) * | 2004-03-02 | 2015-11-11 | EPFL Ecole Polytechnique Fédérale de Lausanne | Specific substrates for o6-alkylguanine-dna alkyltransferase |
| US8178314B2 (en) * | 2005-04-27 | 2012-05-15 | Covalys Biosciences Ag | Pyrimidines reacting with O6-alkylguanine-DNA alkyltransferase fusion protein and method for detecting protein |
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| EP1882688A1 (en) | 2008-01-30 |
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| US20110207157A1 (en) | 2011-08-25 |
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| US8623627B2 (en) | 2014-01-07 |
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