CN101516857A - 用合成探针标记融合蛋白 - Google Patents
用合成探针标记融合蛋白 Download PDFInfo
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- CN101516857A CN101516857A CNA2007800339023A CN200780033902A CN101516857A CN 101516857 A CN101516857 A CN 101516857A CN A2007800339023 A CNA2007800339023 A CN A2007800339023A CN 200780033902 A CN200780033902 A CN 200780033902A CN 101516857 A CN101516857 A CN 101516857A
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- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
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- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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| EP06117779A EP1882688A1 (en) | 2006-07-25 | 2006-07-25 | Labelling of fusion proteins with synthetic probes |
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| CN113444046A (zh) * | 2016-07-20 | 2021-09-28 | 纳莹(上海)生物科技有限公司 | 一种荧光探针及其制备方法和用途 |
| CN118165544A (zh) * | 2022-12-11 | 2024-06-11 | 中国科学院大连化学物理研究所 | 适用于细胞膜动态超分辨成像的五甲川菁染料荧光探针合成与应用 |
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| DE19600934A1 (de) * | 1996-01-12 | 1997-07-17 | Basf Ag | Substituierte Aza- und Diazacycloheptan- und Cyclooctanverbindungen und deren Verwendung |
| CN1420882A (zh) * | 1999-07-28 | 2003-05-28 | 阿温蒂斯药物公司 | 取代的氧代氮杂杂环基化合物 |
| CN1720332A (zh) * | 2002-10-03 | 2006-01-11 | 洛桑生态综合技术联合公司 | O6－烷基鸟嘌呤－dna烷基转移酶的底物 |
| EP1730298B1 (en) * | 2004-03-02 | 2015-11-11 | EPFL Ecole Polytechnique Fédérale de Lausanne | Specific substrates for o6-alkylguanine-dna alkyltransferase |
| US8178314B2 (en) * | 2005-04-27 | 2012-05-15 | Covalys Biosciences Ag | Pyrimidines reacting with O6-alkylguanine-DNA alkyltransferase fusion protein and method for detecting protein |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113444046A (zh) * | 2016-07-20 | 2021-09-28 | 纳莹(上海)生物科技有限公司 | 一种荧光探针及其制备方法和用途 |
| CN113444047A (zh) * | 2016-07-20 | 2021-09-28 | 纳莹(上海)生物科技有限公司 | 一种荧光探针及其制备方法和用途 |
| CN113444047B (zh) * | 2016-07-20 | 2023-06-16 | 纳莹(上海)生物科技有限公司 | 一种荧光探针及其制备方法和用途 |
| CN113444046B (zh) * | 2016-07-20 | 2023-10-27 | 纳莹(上海)生物科技有限公司 | 一种荧光探针及其制备方法和用途 |
| CN118165544A (zh) * | 2022-12-11 | 2024-06-11 | 中国科学院大连化学物理研究所 | 适用于细胞膜动态超分辨成像的五甲川菁染料荧光探针合成与应用 |
| CN118165544B (zh) * | 2022-12-11 | 2025-09-05 | 中国科学院大连化学物理研究所 | 适用于细胞膜动态超分辨成像的五甲川菁染料荧光探针合成与应用 |
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| WO2008012296A1 (en) | 2008-01-31 |
| EP1882688A1 (en) | 2008-01-30 |
| EP2049499A1 (en) | 2009-04-22 |
| JP2009544660A (ja) | 2009-12-17 |
| US20120237961A1 (en) | 2012-09-20 |
| US20110207157A1 (en) | 2011-08-25 |
| US8227602B2 (en) | 2012-07-24 |
| EP2049499B1 (en) | 2012-10-31 |
| US8623627B2 (en) | 2014-01-07 |
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