JP2009541479A5 - - Google Patents
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- Publication number
- JP2009541479A5 JP2009541479A5 JP2009517376A JP2009517376A JP2009541479A5 JP 2009541479 A5 JP2009541479 A5 JP 2009541479A5 JP 2009517376 A JP2009517376 A JP 2009517376A JP 2009517376 A JP2009517376 A JP 2009517376A JP 2009541479 A5 JP2009541479 A5 JP 2009541479A5
- Authority
- JP
- Japan
- Prior art keywords
- cbme
- medicament
- manufacture
- thc
- cbd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 14
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 claims 6
- 229960004242 dronabinol Drugs 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 6
- 229940079593 drugs Drugs 0.000 claims 5
- 241000218236 Cannabis Species 0.000 claims 3
- 208000002193 Pain Diseases 0.000 claims 3
- 208000004296 Neuralgia Diseases 0.000 claims 2
- 230000001154 acute Effects 0.000 claims 2
- 230000002149 cannabinoid Effects 0.000 claims 2
- 229930003827 cannabinoid Natural products 0.000 claims 2
- 239000003557 cannabinoid Substances 0.000 claims 2
- 239000000499 gel Substances 0.000 claims 2
- 230000002093 peripheral Effects 0.000 claims 2
- 229940035676 ANALGESICS Drugs 0.000 claims 1
- 229940005513 ANTIDEPRESSANTS Drugs 0.000 claims 1
- 206010040984 Sleep disease Diseases 0.000 claims 1
- 230000000202 analgesic Effects 0.000 claims 1
- 239000000730 antalgic agent Substances 0.000 claims 1
- 230000001773 anti-convulsant Effects 0.000 claims 1
- 230000001430 anti-depressive Effects 0.000 claims 1
- 239000001961 anticonvulsive agent Substances 0.000 claims 1
- 239000000935 antidepressant agent Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000002685 pulmonary Effects 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
Claims (15)
- 末梢神経因性疼痛の治療のための医薬の製造におけるCBDおよびTHCを含む大麻ベース医学的抽出物（CBME）の使用であって、CBDのTHCに対する重量比が18:1〜30:1である、使用。
- 末梢神経因性疼痛に関連する睡眠障害の治療のための医薬の製造における、請求項１記載のCBMEの使用。
- 純粋THCよりも長い疼痛緩和プロフィールを有する医薬の製造における請求項１または２のいずれか記載のCBMEの使用。
- 急性投与のための医薬の製造における請求項１〜３のいずれか記載のCBMEの使用。
- 毎日繰り返し投与後の疼痛緩和を生じる医薬の製造における請求項１〜３のいずれか記載のCBMEの使用。
- 急性投与後および毎日繰り返し投与後の両方の疼痛緩和を提供する医薬の製造における請求項４または５のいずれか記載のCBMEの使用。
- CBD:THCの重量比が22:1〜26:1である、請求項１〜６のいずれか記載のCBMEの使用。
- CBD:THCの重量比が実質的に24:1である、請求項１〜７のいずれか記載のCBMEの使用。
- 送達が舌下；口腔；非経口；経口；直腸、鼻腔および肺系統からなる群から選択される領域に標的化されるように医薬が梱包される、請求項１〜８のいずれか記載のCBMEの使用。
- 医薬がゲル；ゲルスプレー；錠剤；液剤；カプセルおよび蒸気用からなる群から選択される形態である、請求項９記載のCBMEの使用。
- 医薬が：
a）THCを抽出物中の総カンナビノイド含有量の90%より多く含む大麻ベース医学的抽出物と
b）CBDを抽出物中の総カンナビノイド含有量の90%より多く含む大麻ベース医学的抽出物
との比率化された生成物として製剤化される、請求項１〜１０のいずれか記載のCBMEの使用。 - １以上の他の薬剤との併用である、請求項１〜１１のいずれか記載のCBMEの使用。
- １以上の他の薬剤が１以上の鎮痛剤である、請求項１２記載のCBMEの使用。
- １以上の他の薬剤が１以上のアヘン剤またはアヘン関連薬剤、１以上の抗痙攣剤、および１以上の抗うつ薬からなる群から選択される、請求項１２記載のCBMEの使用。
- １以上の他の薬物と別々に、同時にまたは連続して投与される、請求項１２〜１４のいずれか記載のCBMEの使用。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0612512A GB2439393B (en) | 2006-06-23 | 2006-06-23 | Cannabinoids for use in the treatment of neuropathic pain |
| GB0612512.4 | 2006-06-23 | ||
| PCT/GB2007/002315 WO2007148094A1 (en) | 2006-06-23 | 2007-06-21 | Cannabinoids for use in the treatment of neuropathic pain |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013182318A Division JP2013241471A (ja) | 2006-06-23 | 2013-09-03 | 神経因性疼痛の治療用カンナビノイド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009541479A JP2009541479A (ja) | 2009-11-26 |
| JP2009541479A5 true JP2009541479A5 (ja) | 2010-07-29 |
| JP5399898B2 JP5399898B2 (ja) | 2014-01-29 |
Family
ID=36803806
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009517376A Active JP5399898B2 (ja) | 2006-06-23 | 2007-06-21 | 神経因性疼痛の治療用カンナビノイド |
| JP2013182318A Pending JP2013241471A (ja) | 2006-06-23 | 2013-09-03 | 神経因性疼痛の治療用カンナビノイド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013182318A Pending JP2013241471A (ja) | 2006-06-23 | 2013-09-03 | 神経因性疼痛の治療用カンナビノイド |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20100016418A1 (ja) |
| EP (1) | EP2037902B1 (ja) |
| JP (2) | JP5399898B2 (ja) |
| CA (1) | CA2656698C (ja) |
| ES (1) | ES2429406T3 (ja) |
| GB (1) | GB2439393B (ja) |
| PL (1) | PL2037902T3 (ja) |
| WO (1) | WO2007148094A1 (ja) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8449908B2 (en) | 2000-12-22 | 2013-05-28 | Alltranz, Llc | Transdermal delivery of cannabidiol |
| GB2439393B (en) * | 2006-06-23 | 2011-05-11 | Gw Pharma Ltd | Cannabinoids for use in the treatment of neuropathic pain |
| GB2450753B (en) * | 2007-07-06 | 2012-07-18 | Gw Pharma Ltd | New Pharmaceutical formulation |
| ES2534900T3 (es) | 2007-07-30 | 2015-04-30 | Zynerba Pharmaceuticals, Inc. | Profármacos de cannabidiol, composiciones que comprenden los profármacos de cannabidiol y métodos de uso de los mismos |
| GB2456183A (en) * | 2008-01-04 | 2009-07-08 | Gw Pharma Ltd | Anti-psychotic composition comprising cannabinoids and anti-psychotic medicament |
| GB2471523A (en) * | 2009-07-03 | 2011-01-05 | Gw Pharma Ltd | Use of tetrahydrocannibivarin (THCV) and optionally cannabidiol (CBD) in the treatment of epilepsy |
| GB2478595B (en) * | 2010-03-12 | 2018-04-04 | Gw Pharma Ltd | Phytocannabinoids in the treatment of glioma |
| US8445034B1 (en) | 2010-11-02 | 2013-05-21 | Albert L Coles, Jr. | Systems and methods for producing organic cannabis tincture |
| GB2491118B (en) * | 2011-05-20 | 2015-12-30 | Otsuka Pharma Co Ltd | Cannabinoids for use in the treatment of neuropathic pain |
| CA2895805A1 (en) | 2012-12-18 | 2014-06-26 | Kotzker Consulting Llc | Use of cannabinoids and terpenes for treatment of organophosphate and carbamate toxicity |
| GB2516814B (en) | 2013-06-19 | 2016-08-31 | Otsuka Pharma Co Ltd | Use of phytocannabinoids for increasing radiosensitivity in the treatment of cancer |
| GB2524469A (en) | 2014-02-14 | 2015-09-30 | Kind Consumer Ltd | A cannabinoid inhaler and composition therefor |
| US9918961B2 (en) | 2014-02-19 | 2018-03-20 | Kind Consumer Limited | Cannabinoid inhaler and composition therefor |
| CA2944837C (en) * | 2014-04-21 | 2021-10-26 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Cyclohexenyl compounds, compositions comprising them and uses thereof |
| CA2952934A1 (en) | 2014-06-26 | 2015-12-30 | Island Breeze Systems Ca, Llc | Mdi related products and methods of use |
| WO2016054268A1 (en) | 2014-09-30 | 2016-04-07 | MJAR Holdings, LLC | Methods of growing cannabaceae plants using artificial lighting |
| WO2016092539A1 (en) * | 2014-12-07 | 2016-06-16 | One World Cannabis Ltd | Use of cannabis to treat migraine |
| US20160298151A1 (en) | 2015-04-09 | 2016-10-13 | Sher Ali Butt | Novel Method for the cheap, efficient, and effective production of pharmaceutical and therapeutic api's intermediates, and final products |
| CN107846861A (zh) | 2015-05-28 | 2018-03-27 | 推德有限公司 | Thca合成酶表达改变的大麻植物 |
| AU2016359160A1 (en) | 2015-11-24 | 2018-06-14 | Constance Therapeutics, Inc. | Cannabis oil compositions and methods for preparation thereof |
| US10499584B2 (en) | 2016-05-27 | 2019-12-10 | New West Genetics | Industrial hemp Cannabis cultivars and seeds with stable cannabinoid profiles |
| CN109475586A (zh) | 2016-06-29 | 2019-03-15 | 康纳塞斯创新公司 | 脱羧的大麻树脂、其用途和制备其的方法 |
| US10239808B1 (en) | 2016-12-07 | 2019-03-26 | Canopy Holdings, LLC | Cannabis extracts |
| CN111372907A (zh) * | 2017-09-01 | 2020-07-03 | 普优峰全球股份有限公司 | 合成大麻二酚组合物和用于制备其的方法 |
| EP3681525A4 (en) * | 2017-09-15 | 2020-09-02 | Zelda Therapeutics Operations Pty Ltd | COMPOSITION AND METHOD OF PROCESSING AUTISM |
| EP3684353A4 (en) * | 2017-09-22 | 2021-06-23 | Inmed Pharmaceuticals Inc. | TOPICAL FORMULATIONS OF CANNABINOIDS AND THEIR USES FOR PAIN TREATMENT |
| US20190183849A1 (en) * | 2017-10-21 | 2019-06-20 | Alexander Kariman | Compound and method for treatment of diseases and disorders |
| EP3711752B1 (en) * | 2017-12-20 | 2022-07-20 | Hanyi Bio-Technology Company Ltd. | Use of cannabidiol or cannabis extract in a cosmetic method of skin whitening |
| EP3745884A1 (en) | 2018-01-31 | 2020-12-09 | Canopy Holdings, Llc | Hemp powder |
| GB201806953D0 (en) * | 2018-04-27 | 2018-06-13 | Gw Res Ltd | Cannabidiol Preparations |
| SI25373A (sl) * | 2018-05-08 | 2018-08-31 | Danijela Marković | Naravna orodisperzibilna tableta |
| CA3103504A1 (en) * | 2018-06-15 | 2019-12-19 | CannPal Animal Therapeutics Limited | Cannabinoid composition and methods of treatment using the same |
| WO2020051371A2 (en) * | 2018-09-05 | 2020-03-12 | Noramco, Inc. | Cannabidiol compositions having modified cannabinoid profiles |
| CA3119729A1 (en) | 2018-10-10 | 2020-04-16 | Treehouse Biotech, Inc. | Synthesis of cannabigerol |
| AU2020264426A1 (en) * | 2019-05-01 | 2022-01-06 | Cannadol Pharmaceuticals | Compositions and methods for pain and anxiety relief |
| US12016829B2 (en) | 2019-10-11 | 2024-06-25 | Pike Therapeutics Inc. | Pharmaceutical composition and method for treating seizure disorders |
| US20210401794A1 (en) * | 2020-06-30 | 2021-12-30 | Np Pharma Holdings, Llc | Methods of Using Cannabinoid Compositions for Inducing and Promoting Sleep |
| CA3091622A1 (en) | 2020-08-28 | 2022-02-28 | Teresa Ann Hanlon | Pain relieving formulations containing cannabis and methods of making same |
| WO2022159507A1 (en) * | 2021-01-19 | 2022-07-28 | Merit Therapeutics, Inc. | Combination of cannabinoids with additional therapeutic agents for treating diseases or disorders |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6949582B1 (en) * | 1999-05-27 | 2005-09-27 | Wallace Walter H | Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment |
| CZ306277B6 (cs) * | 2001-02-14 | 2016-11-09 | Gw Pharma Limited | Pumpičkou aktivovaná kapalná sprejová formulace |
| CH695661A5 (de) * | 2001-03-06 | 2006-07-31 | Forsch Hiscia Ver Fuer Krebsfo | Pharmazeutische Zusammensetzung. |
| GB2381450B (en) * | 2001-10-31 | 2006-05-31 | Gw Pharma Ltd | Compositions for administration of natural or synthetic cannabinoids by vaporisation |
| MXPA05001567A (es) * | 2002-08-14 | 2005-04-25 | Gw Pharma Ltd | Formulaciones liquidas de canabinoides para la administracion a traves de la mucosa. |
| GB2391865B (en) * | 2002-08-14 | 2005-06-01 | Gw Pharma Ltd | Improvements in the extraction of pharmaceutically active components from plant materials |
| GB2394894B (en) * | 2002-11-04 | 2005-08-31 | G W Pharma Ltd | New use for pharmaceutical composition |
| GB2414933B (en) * | 2004-06-08 | 2009-07-15 | Gw Pharma Ltd | Cannabinoid compositions for the treatment of disease and/or symptoms in arthritis |
| GB2439393B (en) * | 2006-06-23 | 2011-05-11 | Gw Pharma Ltd | Cannabinoids for use in the treatment of neuropathic pain |
-
2006
- 2006-06-23 GB GB0612512A patent/GB2439393B/en not_active Expired - Fee Related
-
2007
- 2007-06-21 WO PCT/GB2007/002315 patent/WO2007148094A1/en active Application Filing
- 2007-06-21 CA CA2656698A patent/CA2656698C/en active Active
- 2007-06-21 JP JP2009517376A patent/JP5399898B2/ja active Active
- 2007-06-21 EP EP07733311.0A patent/EP2037902B1/en active Active
- 2007-06-21 ES ES07733311T patent/ES2429406T3/es active Active
- 2007-06-21 PL PL07733311T patent/PL2037902T3/pl unknown
- 2007-06-21 US US12/308,776 patent/US20100016418A1/en not_active Abandoned
-
2012
- 2012-06-07 US US13/491,077 patent/US20120245224A1/en not_active Abandoned
-
2013
- 2013-09-03 JP JP2013182318A patent/JP2013241471A/ja active Pending
-
2018
- 2018-09-26 US US16/142,394 patent/US20190224140A1/en not_active Abandoned
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