JP2007119497A5 - - Google Patents

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Publication number
JP2007119497A5
JP2007119497A5 JP2007031760A JP2007031760A JP2007119497A5 JP 2007119497 A5 JP2007119497 A5 JP 2007119497A5 JP 2007031760 A JP2007031760 A JP 2007031760A JP 2007031760 A JP2007031760 A JP 2007031760A JP 2007119497 A5 JP2007119497 A5 JP 2007119497A5
Authority
JP
Japan
Prior art keywords
ifn
stimulator
pharmaceutical composition
composition according
metabolism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007031760A
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English (en)
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JP4616291B2 (ja
JP2007119497A (ja
Filing date
Publication date
Priority claimed from GB9516967A external-priority patent/GB2304342A/en
Application filed filed Critical
Publication of JP2007119497A publication Critical patent/JP2007119497A/ja
Publication of JP2007119497A5 publication Critical patent/JP2007119497A5/ja
Application granted granted Critical
Publication of JP4616291B2 publication Critical patent/JP4616291B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Claims (8)

  1. 慢性創傷の治癒を促進する薬剤の製造におけるIFN−γスティミュレーターの使用。
  2. IFN−γまたはIFN−γの一部修飾体、およびIFN−γ代謝のインヒビターのいずれかひとつから選ばれる請求項1に記載のIFN−γスティミュレーターの使用。
  3. 医薬的に許容しうる担体、希釈剤または賦形剤とともに用いる、請求項1または2のいずれかひとつに記載のIFN−γスティミュレーターの使用。
  4. IFN−γまたはIFN−γの一部修飾体、およびIFN−γ代謝のインヒビターのいずれかひとつから選ばれるIFN−γスティミュレーターを含む、慢性創傷の治癒を促進するための医薬組成物。
  5. IFN−γスティミュレーターを創傷形成の部位に投与するための請求項4に記載の医薬組成物。
  6. IFN−γスティミュレーターが、IFN−γである請求項4または5に記載の医薬組成物
  7. 約7,500〜15,000IUのIFN−γを含む請求項4〜6のいずれかひとつに記載の医薬組成物。
  8. 創傷形成の直前または直後のいずれかに、IFN−γスティミュレーターを投与するための請求項4〜7のいずれかひとつに記載の医薬組成物。
JP2007031760A 1995-08-18 2007-02-13 インターフェロン−ガンマスティミュレーター含有医薬組成物 Expired - Fee Related JP4616291B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9516967A GB2304342A (en) 1995-08-18 1995-08-18 Pharmaceutical comprising either an inhibitor or a stimulator of interferon gamma

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP50902597A Division JP4070809B2 (ja) 1995-08-18 1996-08-09 インターフェロン−ガンマインヒビター含有医薬組成物

Publications (3)

Publication Number Publication Date
JP2007119497A JP2007119497A (ja) 2007-05-17
JP2007119497A5 true JP2007119497A5 (ja) 2008-04-24
JP4616291B2 JP4616291B2 (ja) 2011-01-19

Family

ID=10779448

Family Applications (2)

Application Number Title Priority Date Filing Date
JP50902597A Expired - Fee Related JP4070809B2 (ja) 1995-08-18 1996-08-09 インターフェロン−ガンマインヒビター含有医薬組成物
JP2007031760A Expired - Fee Related JP4616291B2 (ja) 1995-08-18 2007-02-13 インターフェロン−ガンマスティミュレーター含有医薬組成物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP50902597A Expired - Fee Related JP4070809B2 (ja) 1995-08-18 1996-08-09 インターフェロン−ガンマインヒビター含有医薬組成物

Country Status (13)

Country Link
EP (2) EP0845007B1 (ja)
JP (2) JP4070809B2 (ja)
AT (2) ATE231728T1 (ja)
AU (1) AU713809B2 (ja)
CA (1) CA2229590C (ja)
DE (2) DE69616803T2 (ja)
DK (2) DK0845007T3 (ja)
ES (2) ES2164911T3 (ja)
GB (1) GB2304342A (ja)
HK (1) HK1023516A1 (ja)
PT (2) PT972521E (ja)
WO (1) WO1997007136A2 (ja)
ZA (1) ZA966953B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
EP1336654A1 (en) 1998-12-09 2003-08-20 Protein Design Labs, Inc. Method of treating psoriasis using anti-gamma interferon antibody
US6710025B1 (en) 1999-05-26 2004-03-23 The Brigham And Women's Hospital, Inc. Treatment of damaged tissue using agents that modulate the activity of alpha-smooth muscle actin
JP2003500113A (ja) * 1999-05-26 2003-01-07 ザ ブリガム アンド ウイミンズ ホスピタル、 インコーポレイテッド アルファ平滑筋アクチン活性を調節する薬剤の治療的使用
US10080779B2 (en) 2004-12-15 2018-09-25 Universite D'angers Method for increasing the expression of anti-microbial peptides by keratinocytes comprising administering a composition comprising IL-17, TNF-alpha and OSM
WO2008099829A1 (ja) * 2007-02-14 2008-08-21 Japan Science And Technology Agency 実験動物の腸管癒着を形成する方法、腸管癒着実験動物の製造方法、腸管癒着抑制剤のスクリーニング方法及び腸管癒着抑制剤
GB0724231D0 (en) * 2007-12-12 2008-01-30 Renono Ltd Methods for inhibiting scarring
RU2539383C1 (ru) * 2013-11-29 2015-01-20 Закрытое акционерное общество "ФИРН М" (ЗАО "ФИРН М") Фармацевтическая композиция для лечения трофических язв и длительно незаживающих ран различной этиологии в виде мази

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78444A (en) * 1986-04-08 1992-05-25 Yeda Res & Dev Human gamma interferon-specific receptor protein,antibody against said protein,and compositions containing said protein and antibody
WO1987007842A1 (en) * 1986-06-17 1987-12-30 Biogen N.V. Combinations of gamma interferons and anti-inflammatory or anti-pyretic agents and methods for treating diseases
NL8700927A (nl) * 1987-04-16 1988-11-16 Stichting Rega V Z W Anti-interferon-gamma-antilichamen; en hun therapeutische toepassing.
CA1335792C (en) * 1987-08-18 1995-06-06 Chaim O. Jacob Method and dosage form using an antagonist to gamma interferon to control mhc-associated autoimmune disease
AU2855189A (en) * 1988-01-25 1989-07-27 Baker Cummins Dermatologicals, Inc. Method of treating fibrotic disorders
IL88378A (en) * 1988-11-14 2000-11-21 Yeda Res & Dev Human interferon-gamma binding proteins their manufacture and pharmaceutical compositions comprising them
DE68927671T2 (de) * 1988-12-19 1997-05-07 American Cyanamid Co Produkte zur Behandlung des Endotoxin -Schocks bei einem Säugetier
GB8905400D0 (en) * 1989-03-09 1989-04-19 Jonker Margreet Medicaments
ATE132191T1 (de) * 1989-04-19 1996-01-15 Hoffmann La Roche Auflösbare interferon-gamma-rezeptoren sowie verfahren zu deren herstellung
IT1231727B (it) * 1989-08-11 1991-12-21 Enrico Savoldi Peptidi utili per la determinazione e la purificazione di anticorpi anti gamma interferone.
IL91562A0 (en) * 1989-09-07 1990-04-29 Yeda Res & Dev Interferon-gamma receptor fragment and its production
ATE132162T1 (de) * 1990-09-27 1996-01-15 Schering Corp Humane gammainterferonantagonisten
AU1462392A (en) * 1991-02-22 1992-09-15 Amgen, Inc. Use of gm-csf and g-csf to promote accelerated wound healing
NL9101290A (nl) * 1991-07-23 1993-02-16 Stichting Rega V Z W Recombinant dna-molecuul voor de expressie van een fv-fragment van een antilichaam.
DE4234380A1 (de) * 1992-10-06 1994-04-07 Schering Ag Verwendung von Dopaminagonisten zur Aktivierung des gamma-Interferon-Produktion
AU5669694A (en) * 1992-11-20 1994-06-22 Schering Corporation Antagonists of human gamma interferon
WO1994014467A1 (en) * 1992-12-29 1994-07-07 Genentech, Inc. Treatment of inflammatory bowel disease with ifn-gamma inhibitors
WO1995016036A2 (en) * 1993-12-09 1995-06-15 Michel Aguet IFN-ηRECEPTOR β-CHAIN AND DERIVATIVES THEREOF

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