JP2009535344A - 神経炎症性疾患の処置のためのピリダジン化合物を含む処方物 - Google Patents

神経炎症性疾患の処置のためのピリダジン化合物を含む処方物 Download PDF

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JP2009535344A
JP2009535344A JP2009507823A JP2009507823A JP2009535344A JP 2009535344 A JP2009535344 A JP 2009535344A JP 2009507823 A JP2009507823 A JP 2009507823A JP 2009507823 A JP2009507823 A JP 2009507823A JP 2009535344 A JP2009535344 A JP 2009535344A
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JP2009535344A5 (cg-RX-API-DMAC10.html
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マーティン ワッターソン，
エルディク， リンダ バン
ウェンホイ フー，
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ノースウェスタン ユニバーシティ
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/50—Pyridazines; Hydrogenated pyridazines
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JP2009507823A 2006-04-28 2007-04-27 神経炎症性疾患の処置のためのピリダジン化合物を含む処方物 Pending JP2009535344A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79632806P 2006-04-28 2006-04-28
PCT/US2007/010248 WO2007127375A2 (en) 2006-04-28 2007-04-27 Formulations containing pyridazine compounds for treating neuroinflammatory diseases

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JP2009535344A true JP2009535344A (ja) 2009-10-01
JP2009535344A5 JP2009535344A5 (cg-RX-API-DMAC10.html) 2011-06-16

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US (2) US20090325973A1 (cg-RX-API-DMAC10.html)
EP (1) EP2063894B1 (cg-RX-API-DMAC10.html)
JP (1) JP2009535344A (cg-RX-API-DMAC10.html)
CN (1) CN101754762A (cg-RX-API-DMAC10.html)
AU (1) AU2007243280A1 (cg-RX-API-DMAC10.html)
BR (1) BRPI0710938A2 (cg-RX-API-DMAC10.html)
CA (1) CA2650625A1 (cg-RX-API-DMAC10.html)
IL (1) IL194968A0 (cg-RX-API-DMAC10.html)
MX (1) MX2008013843A (cg-RX-API-DMAC10.html)
WO (1) WO2007127375A2 (cg-RX-API-DMAC10.html)

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CA2650711A1 (en) 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
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US20100227793A1 (en) * 2009-03-04 2010-09-09 Scott Thomas Brady Compositions and Methods for Treating Amyotrophic Lateral Sclerosis
TWI510241B (zh) 2010-02-18 2015-12-01 Vtv Therapeutice Llc 苯基－雜芳基衍生物及其使用方法
WO2011156901A2 (en) * 2010-06-17 2011-12-22 Waratah Pharmaceuticals Inc. Compounds, compositions and methods for treatment of multiple sclerosis
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IL311645B2 (en) 2016-07-12 2025-11-01 Revolution Medicines Inc 2,5- disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines asallosteric shp2 inhibitors
CA3051054A1 (en) 2017-01-23 2018-07-26 Revolution Medicines, Inc. Pyridine compounds as allosteric shp2 inhibitors
CN110446709B (zh) 2017-01-23 2023-09-12 锐新医药公司 作为变构shp2抑制剂的二环化合物
TWI852912B (zh) 2017-09-07 2024-08-21 美商銳新醫藥公司 Shp2抑制劑組合物以及治療癌症的方法
BR112020007058A2 (pt) * 2017-10-12 2020-10-06 Revolution Medicines, Inc. compostos de piridina, pirazina, e triazina como inibidores de shp2 alostéricos
BR112020009757A2 (pt) 2017-12-15 2020-11-03 Revolution Medicines, Inc. compostos policíclicos como inibidores alostéricos de shp2
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JP2009535344A (ja) 2006-04-28 2009-10-01 ノースウェスタン ユニバーシティ 神経炎症性疾患の処置のためのピリダジン化合物を含む処方物

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