JP2009532385A5 - - Google Patents

Download PDF

Info

Publication number
JP2009532385A5
JP2009532385A5 JP2009503313A JP2009503313A JP2009532385A5 JP 2009532385 A5 JP2009532385 A5 JP 2009532385A5 JP 2009503313 A JP2009503313 A JP 2009503313A JP 2009503313 A JP2009503313 A JP 2009503313A JP 2009532385 A5 JP2009532385 A5 JP 2009532385A5
Authority
JP
Japan
Prior art keywords
aaa
amino acid
ala
lys
linear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009503313A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009532385A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/065656 external-priority patent/WO2007115182A2/en
Publication of JP2009532385A publication Critical patent/JP2009532385A/ja
Publication of JP2009532385A5 publication Critical patent/JP2009532385A5/ja
Pending legal-status Critical Current

Links

JP2009503313A 2006-03-30 2007-03-30 線状ナトリウム利尿ペプチド構築物 Pending JP2009532385A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74396306P 2006-03-30 2006-03-30
US74396406P 2006-03-30 2006-03-30
PCT/US2007/065656 WO2007115182A2 (en) 2006-03-30 2007-03-30 Linear natriuretic peptide constructs

Publications (2)

Publication Number Publication Date
JP2009532385A JP2009532385A (ja) 2009-09-10
JP2009532385A5 true JP2009532385A5 (https=) 2010-05-20

Family

ID=38564250

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009503313A Pending JP2009532385A (ja) 2006-03-30 2007-03-30 線状ナトリウム利尿ペプチド構築物

Country Status (6)

Country Link
US (1) US7795221B2 (https=)
EP (1) EP2004633A4 (https=)
JP (1) JP2009532385A (https=)
AU (1) AU2007233123A1 (https=)
CA (1) CA2647146A1 (https=)
WO (1) WO2007115182A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8114844B2 (en) 2006-03-30 2012-02-14 Palatin Technologies, Inc. Linear and cyclic melanocortin receptor-specific peptidomimetics
US7795221B2 (en) 2006-03-30 2010-09-14 Palatin Technologies, Inc. Linear natriuretic peptide constructs
EP2001518B1 (en) 2006-03-30 2013-07-10 Palatin Technologies, Inc. Cyclic natriuretic peptide constructs
BRPI0709405A2 (pt) * 2006-03-30 2011-07-12 Palatin Technologies Inc composto lineares ou cìclicos
US7964181B2 (en) 2006-03-30 2011-06-21 Palatin Technologies, Inc. Amino acid surrogates for peptidic constructs
IL186004A0 (en) * 2007-09-17 2008-01-20 Ariel University Res And Dev C Piperzine-based scaffolds for solid phase synthesis of combinatorial libraries and method for their preparation
US20120108514A1 (en) 2009-07-09 2012-05-03 University Of Iowa Research Foundation Long acting atrial natriuretic peptide (la-anp) and methods for use thereof
US8551938B2 (en) * 2009-09-25 2013-10-08 Alcon Research, Ltd. NPR-B agonists
EP2480247B1 (en) * 2009-09-25 2020-02-12 Shire Orphan Therapies GmbH Novel npr-b agonists
AR078446A1 (es) 2009-12-18 2011-11-09 Alcon Res Ltd Agonistas de npr-b. uso.
CN107090028A (zh) 2011-08-30 2017-08-25 梅约医学教育与研究基金会 利钠多肽
US8999990B2 (en) 2011-10-25 2015-04-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2771004B1 (en) * 2011-10-25 2016-05-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9611305B2 (en) 2012-01-06 2017-04-04 Mayo Foundation For Medical Education And Research Treating cardiovascular or renal diseases
US20140066367A1 (en) * 2012-08-31 2014-03-06 Mayo Foundation For Medical Education And Research Subcutaneous delivery of a long-acting natriuretic peptide
EP3698815B1 (en) 2014-03-21 2024-02-21 University of Pittsburgh- Of the Commonwealth System of Higher Education Terminally sterilized hydrogel derived from extracellular matrix
WO2015175502A2 (en) * 2014-05-12 2015-11-19 Palatin Technologies, Inc. Replacement therapy for natriuretic peptide deficiencies
US11406736B2 (en) 2016-01-13 2022-08-09 University of Pittsburgh—Of the Commonwealth Systems of Higher Education Vascular extracellular matrix hydrogel
EA202193345A1 (ru) 2019-06-12 2022-03-16 Новартис Аг Антитела к рецептору-1 натрийуретического пептида и способы их применения
WO2025054172A1 (en) 2023-09-05 2025-03-13 E-Star Biotech, LLC Formulations of manp and uses thereof

Family Cites Families (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US465158A (en) * 1891-12-15 Charles m
US4251438A (en) * 1979-06-14 1981-02-17 The Upjohn Company Piperazinone and piperazine polypeptides
US4341698A (en) 1979-06-21 1982-07-27 Richardson-Merrell Inc. Enkaphalin derivatives
US4496544A (en) * 1983-11-10 1985-01-29 Washington University Atrial Peptides
US4952561A (en) * 1984-02-07 1990-08-28 Merck & Co., Inc. Cardiac atrial peptides
JPS60184098A (ja) * 1984-03-02 1985-09-19 Suntory Ltd 新規なペプチド及びこれを有効成分とする利尿剤
DE3588006T2 (de) 1984-04-19 1995-08-10 Scios Nova Inc Atrielle natriumuretische/gefässerweiterende polypeptide.
US4618600A (en) * 1984-04-19 1986-10-21 Biotechnology Research Associates, J.V. Novel polypeptide diuretic/vasodilators
US5212286A (en) * 1984-04-19 1993-05-18 Scios Nova Inc. Atrial natriuretic/vasodilator peptide compounds
EP0177610A1 (en) 1984-04-24 1986-04-16 The Salk Institute For Biological Studies Atrial peptide analogs
JPH0672155B2 (ja) * 1984-08-24 1994-09-14 塩野義製薬株式会社 α−hANP抗血清作製用ポリペプチド
US4609725A (en) * 1984-10-09 1986-09-02 Merck & Co., Inc. Cardiac atrial peptides
US4757048A (en) * 1985-11-05 1988-07-12 Biotechnology Research Associates J.V. Synthetic analogs of atrial natriuretic peptides
IE862891L (en) * 1985-11-05 1987-05-05 Behringwerke Ag Analogs of atrial natriuretic peptides
DE3614833A1 (de) * 1986-01-16 1987-07-23 Hoechst Ag Peptide mit vasorelaxierender, natriuretischer und diuretischer wirkung, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
US5057603A (en) * 1986-01-31 1991-10-15 Merck & Co., Inc. Peptides having ANF activity
US4716147A (en) * 1986-03-27 1987-12-29 Monsanto Company Synthetic airial peptides
EP0246795A3 (en) * 1986-05-20 1990-04-04 Advanced Peptide Development Limited Synthetic natriuretic peptides
US5159061A (en) * 1986-09-29 1992-10-27 Takeda Chemical Industries, Ltd. Atrial natriuretic peptide derivative
US4804650A (en) * 1986-10-28 1989-02-14 Biotechnology Research Associates, J.V. Analogs of atrial natriuretic peptides
DK531986D0 (da) 1986-11-07 1986-11-07 Novo Industri As Peptider
DE3878231T2 (de) 1987-03-02 1993-05-27 Bissendorf Peptide Gmbh Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung.
US5376635A (en) * 1987-03-15 1994-12-27 Bio-Mega/Boehringer Ingelheim Research Inc. Fluorine containing atrial natriuretic peptides
IL85728A (en) * 1987-03-25 1993-01-14 Bio Mega Inc Fluorine containing atrial natriuretic peptides, their preparation and pharmaceutical compositions containing them
US5091366A (en) * 1987-05-19 1992-02-25 Merck & Co., Inc. Peptides having ANF activity
US4816443A (en) * 1987-05-19 1989-03-28 Merck & Co., Inc. Piptides having ANF activity
IL86386A0 (en) 1987-05-21 1988-11-15 Merrell Dow Pharma Novel anf derivatives
JP2544929B2 (ja) * 1987-06-17 1996-10-16 第一化学薬品 株式会社 新規生理活性ペプチド
US4935492A (en) * 1987-12-24 1990-06-19 California Biotechnology Inc. Cyclic analogs of atrial natriuretic peptides
AU2927889A (en) 1987-12-24 1989-07-19 California Biotechnology, Inc. Linear analogs of atrial natriuretic peptides
US5047397A (en) * 1988-08-26 1991-09-10 California Biotechnology Inc. Linear analogs of atrial natriuretic peptides
WO1989010935A1 (en) 1988-05-09 1989-11-16 Abbott Laboratories Atrial peptide derivatives
US5114923A (en) * 1988-05-31 1992-05-19 California Biotechnology Inc. Recombinant techniques for production of novel natriuretic and vasodilator peptides
CA1339210C (en) * 1988-05-31 1997-08-05 John Lewicki Recombinant techniques for production of novel natriuretic and vasodilator peptides
US5057495A (en) * 1988-06-24 1991-10-15 Queen's University At Kingston Atrial hypotensive peptide
DK380288D0 (da) 1988-07-07 1988-07-07 Novo Industri As Hidtil ukendet peptider
WO1990001940A1 (en) 1988-08-18 1990-03-08 California Biotechnology Inc. Atrial natriuretic peptide clearance inhibitors
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5106834A (en) * 1988-12-27 1992-04-21 G. D. Searle & Co. Linear free-sulfhydryl-containing oligopeptide derivatives as antihypertensive agents
EP0385476B2 (en) 1989-03-01 1999-09-22 SHIONOGI & CO., LTD. Physiologically active polypeptide and DNA
GR1001018B (el) 1989-05-24 1993-03-31 Abbott Lab Μεθοδος παρασκευης προδρομικων πεπτικων παραγωγων.
JP3394040B2 (ja) * 1989-06-23 2003-04-07 ジェネンテック・インコーポレーテッド ナトリウム排泄増加性蛋白質受容体bの組成物および合成法および使用法
ES2117642T3 (es) * 1990-05-10 1998-08-16 Bechgaard Int Res Preparado farmaceutico que contiene n-glicofuroles y n-etilen glicoles.
US5204328A (en) * 1990-06-26 1993-04-20 Merck & Co., Inc. Peptides having atrial natriuretic factor activity
US5202239A (en) 1990-08-07 1993-04-13 Scios Nova Inc. Expression of recombinant polypeptides with improved purification
WO1992006998A1 (de) 1990-10-11 1992-04-30 Boehringer Ingelheim Kg Cyclopeptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JP2809533B2 (ja) 1991-01-31 1998-10-08 壽之 松尾 Cnp類似体ペプチド
US5190922A (en) 1991-06-04 1993-03-02 Abbott Laboratories Terminally modified tri-, tetra- and pentapeptide anaphylatoxin receptor ligands
JP2925391B2 (ja) * 1992-01-09 1999-07-28 サントリー株式会社 Ards治療用医薬組成物
US5977070A (en) * 1992-07-14 1999-11-02 Piazza; Christin Teresa Pharmaceutical compositions for the nasal delivery of compounds useful for the treatment of osteoporosis
WO1994020534A1 (en) * 1993-03-03 1994-09-15 Mayo Foundation For Medical Education And Research Vasonatrin peptide and analogs thereof
US5681811A (en) * 1993-05-10 1997-10-28 Protein Delivery, Inc. Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same
US5359030A (en) * 1993-05-10 1994-10-25 Protein Delivery, Inc. Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same
TW394760B (en) 1993-09-07 2000-06-21 Hoffmann La Roche Novel Carboxamides, process for their preparation and pharmaceutical composition containing the same
US6525022B1 (en) * 1993-11-12 2003-02-25 Genentech, Inc. Receptor specific atrial natriuretic peptides
DE69432123T2 (de) 1993-11-12 2004-01-08 Genentech, Inc., South San Francisco Rezeptor spezifische atrio-natriuretische peptide
US5846932A (en) * 1993-11-12 1998-12-08 Genentech, Inc. Receptor specific atrial natriuretic peptides
US5665704A (en) * 1993-11-12 1997-09-09 Genentech, Inc. Receptor specific atrial natriuretic peptides
US5567662A (en) * 1994-02-15 1996-10-22 The Dow Chemical Company Method of making metallic carbide powders
FR2717484A1 (fr) 1994-03-16 1995-09-22 Pf Medicament Nouveaux composés pseudo-bis-peptidiques analogues de la CCK, leur procédé de préparation, leur utilisation à titre de médicament et les compositions pharmaceutiques les comprenant .
US6150402A (en) * 1994-08-15 2000-11-21 Loma Linda University Medical Center Natriuretic compounds
US5932462A (en) * 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
US5672662A (en) * 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
CA2248140C (en) * 1996-03-04 2005-02-01 Ronald P. Mischak Assay and reagents for quantifying hbnp
US6028055A (en) * 1996-10-22 2000-02-22 Genetech, Inc. Receptor selective BNP
ATE203157T1 (de) * 1996-12-20 2001-08-15 Alza Corp Injizierbare depotgelzubereitung und herstellungsverfahren
US5908825A (en) * 1997-01-09 1999-06-01 University Of Maryland At Baltimore Dosage composition for nasal delivery and method of use of the same
US5965533A (en) * 1997-05-23 1999-10-12 Baxter International Inc. Atrial natriuretic peptide (ANP) as an additive to peritoneal dialysis solutions
US6013630A (en) 1997-08-21 2000-01-11 Curagen Corporation Atrial natriuretic factor mutants and ischemic stroke
WO1999012576A2 (en) 1997-09-11 1999-03-18 Musc Foundation For Research Development Methods and compositions for treating cardiac and renal disorders with atrial natriuretic peptide and tissue kallikrein gene therapy
US6193991B1 (en) * 1997-10-29 2001-02-27 Atul J. Shukla Biodegradable delivery systems of biologically active substances
CN1169573C (zh) 1998-09-28 2004-10-06 参天制药株式会社 用于治疗角结膜障碍的、包含作为活性组分的钠尿肽的泪液分泌促进剂或滴眼剂
US20040266673A1 (en) * 2002-07-31 2004-12-30 Peter Bakis Long lasting natriuretic peptide derivatives
US6309633B1 (en) * 1999-06-19 2001-10-30 Nobex Corporation Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same
US6387932B1 (en) * 1999-06-25 2002-05-14 Merck & Co., Inc. Somatostatin agonists
AU7352200A (en) 1999-09-01 2001-03-26 Regents Of The University Of California, The Novel natriuretic peptide receptors, interacting compounds and methods of regulating proliferation and/or survival of neurons
US6407211B1 (en) * 1999-12-17 2002-06-18 Mayo Foundation For Medical Education And Research Chimeric natriuretic peptides
AU781839B2 (en) * 1999-12-22 2005-06-16 Nektar Therapeutics Sterically hindered derivatives of water soluble polymers
US6911447B2 (en) 2001-04-25 2005-06-28 The Procter & Gamble Company Melanocortin receptor ligands
US6858580B2 (en) * 2001-06-04 2005-02-22 Nobex Corporation Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US20050113286A1 (en) * 2002-03-18 2005-05-26 Schreiner George F. Methods for treating congestive heart failure
WO2003081246A1 (en) * 2002-03-18 2003-10-02 Scios Inc. Treatment of congestive heart failure with natriuretic peptide and a diuretic
US20040077537A1 (en) * 2002-03-18 2004-04-22 Schreiner George F. Method for treating congestive heart failure
AU2003297583B2 (en) 2002-11-26 2010-01-14 Biocon, Ltd Modified naturetic compounds, conjugates, and uses thereof
WO2004075923A2 (en) * 2003-02-26 2004-09-10 Nektar Therapeutics Al, Corporation Polymer-factor viii moiety conjugates
WO2005070446A1 (en) * 2004-01-15 2005-08-04 Scios Inc. Method for treating cardiac remodeling following myocardial injury
MX2007001667A (es) * 2004-08-11 2007-10-02 Johnson & Johnson Aparato y metodo para el suministro transdermico de peptidos natriureticos.
US7795221B2 (en) 2006-03-30 2010-09-14 Palatin Technologies, Inc. Linear natriuretic peptide constructs
EP2001518B1 (en) 2006-03-30 2013-07-10 Palatin Technologies, Inc. Cyclic natriuretic peptide constructs

Similar Documents

Publication Publication Date Title
JP2009532385A5 (https=)
JP2009532384A5 (https=)
JP2012530145A5 (https=)
JP2013518115A5 (https=)
AU2023203430B2 (en) Novel glp-1 analogues
ES2558155T3 (es) Compuestos que muestran actividad antagonista de glucacón y agonista de GLP-1
JP2011502159A5 (https=)
Zhang et al. Converting peptides into drug leads by lipidation
AU2020334993B2 (en) Methods of making incretin analogs
RU2012101274A (ru) Соединения глюкагона, активные в отношении рецептора gip
TW202202518A (zh) 腸促胰島素(incretin)類似物及其用途
RU2012136450A (ru) Конъюгаты антагонист глюкагона - агонист gip и композиции для лечения метаболических расстройств и ожирения
RU2013154047A (ru) Пептидные лекарственные препараты с повышенной эффективностью против инсулинорезистентности
JP2011524420A5 (https=)
RU2012105355A (ru) Производное аналога glp-1 или его фармацевтически приемлемые соли и их применение
RU2015145593A (ru) Пептидные композиции
TW200408402A (en) Growth hormone releasing peptides
JP2011502155A5 (https=)
AU2009335711A1 (en) Dipeptide linked medicinal agents
WO2011038066A4 (en) Novel npr-b agonists
HUT50487A (en) Process for production of peptides
DE69528531T2 (de) D-2-alkyltryptophan enthaltende polypeptide mit wachstumhormon freisetzender aktivitaet
AU2022222674A1 (en) Glucagon-like peptide-1 receptor antagonists
KR100360975B1 (ko) 위장운동자극활성을가지는폴리펩티드
AR076950A2 (es) Analogos del peptido 1-similar al glucagon uso de los mismos para la manufactura de un medicamento y composiciones farmaceuticas que los contienen