JP2009532053A5 - - Google Patents

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Publication number
JP2009532053A5
JP2009532053A5 JP2009503661A JP2009503661A JP2009532053A5 JP 2009532053 A5 JP2009532053 A5 JP 2009532053A5 JP 2009503661 A JP2009503661 A JP 2009503661A JP 2009503661 A JP2009503661 A JP 2009503661A JP 2009532053 A5 JP2009532053 A5 JP 2009532053A5
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JP
Japan
Prior art keywords
domain
sequence
cell
molecule
cytidine deaminase
Prior art date
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Pending
Application number
JP2009503661A
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English (en)
Japanese (ja)
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JP2009532053A (ja
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Publication date
Priority claimed from GBGB0607063.5A external-priority patent/GB0607063D0/en
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Publication of JP2009532053A publication Critical patent/JP2009532053A/ja
Publication of JP2009532053A5 publication Critical patent/JP2009532053A5/ja
Pending legal-status Critical Current

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JP2009503661A 2006-04-07 2007-04-10 インヴィヴォでの核酸配列のエピジェネティック修飾用組成物および方法 Pending JP2009532053A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US79027306P 2006-04-07 2006-04-07
GBGB0607063.5A GB0607063D0 (en) 2006-04-07 2006-04-07 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo
US79794206P 2006-05-05 2006-05-05
GBGB0623644.2A GB0623644D0 (en) 2006-04-07 2006-11-27 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo
PCT/GB2007/001304 WO2007128982A2 (en) 2006-04-07 2007-04-10 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo

Publications (2)

Publication Number Publication Date
JP2009532053A JP2009532053A (ja) 2009-09-10
JP2009532053A5 true JP2009532053A5 (https=) 2010-05-27

Family

ID=36539563

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009503661A Pending JP2009532053A (ja) 2006-04-07 2007-04-10 インヴィヴォでの核酸配列のエピジェネティック修飾用組成物および方法

Country Status (5)

Country Link
US (2) US8298529B2 (https=)
EP (1) EP2010660B1 (https=)
JP (1) JP2009532053A (https=)
GB (2) GB0607063D0 (https=)
WO (1) WO2007128982A2 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5746016B2 (ja) * 2008-04-30 2015-07-08 サンバイオ，インコーポレイティド Ｄｎａメチル化における改変を伴う神経再生細胞連邦政府の援助に関する申告適用なし
EP2128259A1 (en) 2008-05-27 2009-12-02 Koninklijke Philips Electronics N.V. Therapy delivery and monitoring using a gene of interest-reporter fusion protein and optical imaging
EP2414507B1 (en) * 2009-04-03 2014-07-02 Medical Research Council Mutants of activation-induced cytidine deaminase (aid) and methods of use
EP2258858A1 (en) * 2009-06-05 2010-12-08 Universitätsklinikum Freiburg Transgenic LSD1 animal model for cancer
US20110104787A1 (en) * 2009-11-05 2011-05-05 President And Fellows Of Harvard College Fusion Peptides That Bind to and Modify Target Nucleic Acid Sequences
EP2513296A4 (en) * 2009-12-18 2013-05-22 Univ Leland Stanford Junior USE OF CYTIDINE DAMINASE ASSOCIATED ACTIVITIES TO PROMOTE DEMETHYLATION AND CELL REPROGRAMMEIRING
JP6214530B2 (ja) 2011-07-15 2017-10-18 ザ ジェネラル ホスピタル コーポレイション 転写活性化因子様エフェクターの組立て方法
US9890364B2 (en) * 2012-05-29 2018-02-13 The General Hospital Corporation TAL-Tet1 fusion proteins and methods of use thereof
EP3789405A1 (en) 2012-10-12 2021-03-10 The General Hospital Corporation Transcription activator-like effector (tale) - lysine-specific demethylase 1 (lsd1) fusion proteins
EP2954042B1 (en) 2013-02-07 2017-12-06 The General Hospital Corporation Tale transcriptional activators
US9721248B2 (en) 2014-03-04 2017-08-01 Bank Of America Corporation ATM token cash withdrawal
GB201418965D0 (https=) 2014-10-24 2014-12-10 Ospedale San Raffaele And Fond Telethon
US10460367B2 (en) 2016-04-29 2019-10-29 Bank Of America Corporation System for user authentication based on linking a randomly generated number to the user and a physical item
US10268635B2 (en) 2016-06-17 2019-04-23 Bank Of America Corporation System for data rotation through tokenization
CN110168092A (zh) * 2016-12-28 2019-08-23 特朗斯吉有限公司 溶瘤病毒和治疗分子
KR102922694B1 (ko) 2018-04-19 2026-02-03 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 유전자 편집을 위한 조성물 및 방법
AU2019326408A1 (en) * 2018-08-23 2021-03-11 Sangamo Therapeutics, Inc. Engineered target specific base editors
JP7059965B2 (ja) * 2019-02-21 2022-04-26 株式会社豊田中央研究所 エピゲノム状態を制御する融合タンパク質及びその利用
US11680109B2 (en) 2019-05-29 2023-06-20 Duke University Compositions and methods for detection and measurement of RNA modifications through targeted RNA editing
CN113383749B (zh) * 2020-03-12 2025-11-18 中国医学科学院基础医学研究所 一种使用单个肿瘤细胞构建小鼠肿瘤模型的方法
JP7823919B2 (ja) * 2021-05-20 2026-03-04 国立大学法人群馬大学 エピゲノムが改変された動植物の親系統の製造に用いるための組成物およびその用途

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FR2646438B1 (fr) 1989-03-20 2007-11-02 Pasteur Institut Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration
DK0969822T3 (da) * 1996-12-30 2003-07-21 Univ Johns Hopkins Med Bestemmelse af et organs eller vævs tilbøjelighed til cancer ved bestemmelse af dets prægningsmønster
US6534261B1 (en) * 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
WO2000058480A1 (en) * 1999-03-29 2000-10-05 Kansai Technology Licensing Organization Co., Ltd. Novel cytidine deaminase
AUPQ655100A0 (en) * 2000-03-29 2000-04-20 Am Asset Management Pty Ltd Device and method for cleaning golf balls
ATE353361T1 (de) * 2000-04-28 2007-02-15 Sangamo Biosciences Inc Gezielten modifikation der chromatinstruktur
WO2002008286A2 (en) * 2000-07-21 2002-01-31 Syngenta Participations Ag Zinc finger domain recognition code and uses thereof
AU2002228841C1 (en) * 2000-12-07 2006-11-23 Sangamo Biosciences, Inc Regulation of angiogenesis with zinc finger proteins
WO2003012051A2 (en) 2001-07-31 2003-02-13 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Inhibitor of dna methylation
AU2003229998A1 (en) * 2002-05-10 2003-11-11 Medical Research Council Activation induced deaminase (aid)
GB0312676D0 (en) * 2003-06-02 2003-07-09 Babraham Inst Binding assay
FR2875239B1 (fr) * 2004-09-10 2007-07-20 Inst Necker Ass Loi De 1901 Procede pour l'acceleration des mutations somatiques et son application en proteomique

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