JP2009529657A5 - - Google Patents
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- Publication number
- JP2009529657A5 JP2009529657A5 JP2008555179A JP2008555179A JP2009529657A5 JP 2009529657 A5 JP2009529657 A5 JP 2009529657A5 JP 2008555179 A JP2008555179 A JP 2008555179A JP 2008555179 A JP2008555179 A JP 2008555179A JP 2009529657 A5 JP2009529657 A5 JP 2009529657A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- cross
- collection
- igiv
- misfolded
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004169 proteins and genes Human genes 0.000 claims 46
- 108090000623 proteins and genes Proteins 0.000 claims 46
- 238000000034 method Methods 0.000 claims 16
- 239000000523 sample Substances 0.000 claims 14
- 239000012530 fluid Substances 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 230000000694 effects Effects 0.000 claims 4
- 239000007864 aqueous solution Substances 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 210000001539 phagocyte Anatomy 0.000 claims 2
- 239000013074 reference sample Substances 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 102000014914 Carrier Proteins Human genes 0.000 claims 1
- 206010057249 Phagocytosis Diseases 0.000 claims 1
- 108091008324 binding proteins Proteins 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000014207 opsonization Effects 0.000 claims 1
- 230000008782 phagocytosis Effects 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 108020005087 unfolded proteins Proteins 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06075355A EP1820806A1 (en) | 2006-02-16 | 2006-02-16 | Affinity regions |
| PCT/NL2007/050063 WO2007094668A1 (en) | 2006-02-16 | 2007-02-16 | Affinity regions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009529657A JP2009529657A (ja) | 2009-08-20 |
| JP2009529657A5 true JP2009529657A5 (cg-RX-API-DMAC7.html) | 2010-04-15 |
Family
ID=36792791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008555179A Pending JP2009529657A (ja) | 2006-02-16 | 2007-02-16 | アフィニティ領域 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20090155254A1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP1820806A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2009529657A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101421304A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007215621A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0707848A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2642828A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007094668A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200807630B (cg-RX-API-DMAC7.html) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1380290A1 (en) * | 2002-07-09 | 2004-01-14 | Universitair Medisch Centrum Utrecht | Cross-beta structure pathway and its therapeutic relevance |
| US20070003552A1 (en) * | 2002-07-09 | 2007-01-04 | Gebbink Martijn F B | Cross-beta structure comprising amyloid binding proteins and methods for detection of the cross-beta structure, for modulating cross-beta structures fibril formation and for modulating cross-beta structure-mediated toxicity and method for interfering with blood coagulation |
| US20090202980A1 (en) * | 2005-03-21 | 2009-08-13 | Crossbeta Biosciences B.V. | Cross-Beta Structure Comprising Amyloid Binding Proteins and Methods for Detection of the Cross-Beta Structure, for Modulating Cross-Beta Structures Fibril Formation and for Modulating Cross-Beta Structure-Mediated Toxicity and Method for Interfering With Blood Coagulation |
| WO2007008072A2 (en) * | 2005-07-13 | 2007-01-18 | Crossbeta Biosciences B.V. | CROSS-ß STRUCTURE BINDING COMPOUNDS |
| US8114832B2 (en) * | 2005-07-13 | 2012-02-14 | Crossbeta Biosciences B.V. | Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition |
| EP1907864A2 (en) * | 2005-07-13 | 2008-04-09 | Crossbeta Biosciences B.V. | METHODS FOR DETERMINING THE EFFECT OF A TREATMENT ON THE CROSS-ß STRUCTURE CONTENT OF A PROTEIN; SELECTION OF TREATMENTS AND USES THEREOF |
| US20100015126A1 (en) * | 2006-03-17 | 2010-01-21 | Martijn Frans Ben Gerard Gebbink | Methods of Binding of Cross-Beta Structures By Chaperones |
| JP5229789B2 (ja) * | 2007-02-27 | 2013-07-03 | プリマハム株式会社 | 新規ストレスバイオマーカー及びその用途 |
| EP2058001A1 (en) * | 2007-11-08 | 2009-05-13 | Crossbeta Biosciences B.V. | Enhancement of immunogenicity of antigens |
| EP2058000A1 (en) * | 2007-11-08 | 2009-05-13 | Crossbeta Biosciences B.V. | Immunogenic compositions capable of activating T cells |
| CA2716521A1 (en) | 2008-02-29 | 2009-09-11 | Baxter Healthcare S.A. | Anti-amyloid .beta. activity of intravenous immunoglobulin (ivig) in vitro |
| DE102011003944A1 (de) | 2011-02-10 | 2012-08-16 | Oxprotect Gmbh | Detektion und Entfernung von missgefalteten Proteinen/Peptiden |
| EP3022225B1 (en) * | 2013-07-19 | 2021-09-29 | Board Of Regents Of the University Of Texas System | Transthyretin amyloid-selective and polyreactive catabodies |
| PL3191599T3 (pl) * | 2014-09-11 | 2023-12-27 | Board Of Regents Of The University Of Texas System | Wykrywanie nieprawidłowo sfałdowanych białek |
| US20170329892A1 (en) * | 2016-05-10 | 2017-11-16 | Accutar Biotechnology Inc. | Computational method for classifying and predicting protein side chain conformations |
| EP3309550A1 (en) * | 2016-10-12 | 2018-04-18 | sphingotec GmbH | Method for the detection of apolipoprotein e4 |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| CN113390836B (zh) * | 2020-03-13 | 2023-09-29 | 吉林大学 | 硫磺素t的应用及一种牛奶中酪蛋白的检测方法 |
| CN114441466B (zh) * | 2020-11-04 | 2025-03-28 | 厦门红观生物科技有限公司 | 一种利用ApoJ抑制ApoB100热聚集的方法及定量检测ApoJ活性的方法 |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5733524A (en) * | 1984-03-19 | 1998-03-31 | The Picower Institute For Medical Research | Methods and materials for the diagnosis and treatment of conditions such as stroke |
| US5801200A (en) * | 1984-03-19 | 1998-09-01 | The Picower Institute For Medical Research | Methods and materials for the diagnosis and treatment of conditions such as stroke |
| US5700447A (en) * | 1992-05-21 | 1997-12-23 | The Picowder Institute For Medical Research | Methods and materials for the diagnosis and treatment of conditions such as stroke |
| US5869534A (en) * | 1992-05-21 | 1999-02-09 | The Picower Institute For Medical Research | Glycosylation of lipids and lipid-containing particles, and diagnostic and therapeutic methods and materials derived therefrom |
| US5733933A (en) * | 1984-03-19 | 1998-03-31 | The Picower Institute For Medical Research | Methods and materials for the diagnosis and treatment of conditions such as stroke |
| EP0319144A1 (en) * | 1987-11-06 | 1989-06-07 | Asahi Kasei Kogyo Kabushiki Kaisha | Adsorbent of beta 2-microglobulin |
| EP0321703B1 (en) * | 1987-11-20 | 1993-04-28 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Absorbent for serum amyloid protein |
| US5216127A (en) * | 1987-11-20 | 1993-06-01 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Adsorbent for serum amyloid protein |
| US5180615A (en) * | 1989-12-13 | 1993-01-19 | W.R. Grace & Co.-Conn. | Metallized bag for static protection of electronic components |
| US5650418A (en) * | 1990-06-04 | 1997-07-22 | Therapy 2000 | Therapeutic lysine salt composition and method of use |
| US5278189A (en) * | 1990-06-04 | 1994-01-11 | Rath Matthias W | Prevention and treatment of occlusive cardiovascular disease with ascorbate and substances that inhibit the binding of lipoprotein (A) |
| US5230996A (en) * | 1990-06-04 | 1993-07-27 | Therapy 2000 | Use of ascorbate and tranexamic acid solution for organ and blood vessel treatment prior to transplantation |
| US5780587A (en) * | 1990-08-24 | 1998-07-14 | President And Fellows Of Harvard College | Compounds and methods for inhibiting β-protein filament formation and neurotoxicity |
| US5276059A (en) * | 1992-07-10 | 1994-01-04 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibition of diseases associated with amyloid formation |
| US5958883A (en) * | 1992-09-23 | 1999-09-28 | Board Of Regents Of The University Of Washington Office Of Technology | Animal models of human amyloidoses |
| US5560418A (en) * | 1993-04-02 | 1996-10-01 | Advantage Office Systems, L.L.C. | Attachment bar for partition panel |
| US5449663A (en) * | 1993-06-11 | 1995-09-12 | Bicher; Haim I. | Antineoplastic compositions |
| US5935927A (en) * | 1994-02-03 | 1999-08-10 | The Picower Institute For Medical Research | Compositions and methods for stimulating amyloid removal in amyloidogenic diseases using advanced glycosylation endproducts |
| US6410598B1 (en) * | 1994-02-03 | 2002-06-25 | Michael P. Vitek | Compositions and methods for advanced glycosylation endproduct-mediated modulation of amyloidosis |
| US5589154A (en) * | 1994-11-22 | 1996-12-31 | Rutgers, The State University Of New Jersey | Methods for the prevention or treatment of vascular hemorrhaging and Alzheimer's disease |
| US6136548A (en) * | 1994-11-22 | 2000-10-24 | Rutgers, The State University Of New Jersey | Methods for identifying useful T-PA mutant derivatives for treatment of vascular hemorrhaging |
| US5854215A (en) * | 1995-03-14 | 1998-12-29 | Praecis Pharmaceuticals Incorporated | Modulators of β-amyloid peptide aggregation |
| CA2214247C (en) * | 1995-03-14 | 2004-02-10 | Praecis Pharmaceuticals Incorporated | Modulators of amyloid aggregation |
| US5817626A (en) * | 1995-03-14 | 1998-10-06 | Praecis Pharmaceuticals Incorporated | Modulators of beta-amyloid peptide aggregation |
| US5948763A (en) * | 1995-06-07 | 1999-09-07 | New York University | Peptides and pharmaceutical compositions thereof for treatment of disorders or diseases associated with abnormal protein folding into amyloid or amyloid-like deposits |
| US6436969B1 (en) * | 1995-09-12 | 2002-08-20 | Kansas University Medical Center Research Institute Inc. | Dialysis solutions and methods |
| US5985242A (en) * | 1995-10-27 | 1999-11-16 | Praecis Pharmaceuticals, Inc. | Modulators of β-amyloid peptide aggregation comprising D-amino acids |
| US6310046B1 (en) * | 1995-11-17 | 2001-10-30 | The United States Of America As Represented By The Secretary Of The Army | Sequestrin of Plasmodium falciparum |
| WO1997026919A2 (en) * | 1996-01-24 | 1997-07-31 | Warner-Lambert Company | Method of imaging amyloid deposits |
| US5785187A (en) * | 1996-04-29 | 1998-07-28 | Lipman; Daniel | Mechandising display assembly |
| US6034211A (en) * | 1996-06-03 | 2000-03-07 | Kelly; Jeffery W. | β-sheet nucleating peptidomimetics |
| US6929807B1 (en) * | 1996-08-09 | 2005-08-16 | Mannatech, Inc. | Compositions of plant carbohydrates as dietary supplements |
| US6372473B1 (en) * | 1997-05-28 | 2002-04-16 | Human Genome Sciences, Inc. | Tissue plasminogen activator-like protease |
| EP1014996B1 (en) * | 1997-08-28 | 2003-05-28 | University of Washington | Saccharide-containing compositions for treating alzheimer's disease and other amyloidoses |
| CA2306875C (en) * | 1997-10-24 | 2011-01-04 | John P. Blass | Nutritional supplement for cerebral metabolic insufficiencies |
| WO1999060024A1 (en) * | 1998-05-21 | 1999-11-25 | The University Of Tennessee Research Corporation | Methods for amyloid removal using anti-amyloid antibodies |
| JP2001227537A (ja) * | 2000-02-18 | 2001-08-24 | Nsk Ltd | 直動案内装置 |
| AU783144B2 (en) * | 2000-02-21 | 2005-09-29 | H. Lundbeck A/S | Novel method for down-regulation of amyloid |
| HUP0300067A3 (en) * | 2000-02-21 | 2010-03-29 | Lundbeck & Co As H | Novel method for down-regulation of amyloid |
| EP1130031A1 (en) * | 2000-02-25 | 2001-09-05 | Universitair Medisch Centrum Utrecht | Method for inhibiting angiogenesis using molecules that enhance plasmin formation or prolong plasmin activity |
| EP1172378A1 (en) * | 2000-07-12 | 2002-01-16 | Richard Dr. Dodel | Human beta-amyloid antibody and use thereof for treatment of alzheimer's disease |
| EP2264018B1 (en) * | 2000-08-24 | 2015-02-11 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Thioflavin derivatives for use in the diagnosis of Alzheimer's disease |
| US7270800B2 (en) * | 2000-08-24 | 2007-09-18 | University Of Pittsburgh | Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition |
| CA2453403C (en) * | 2001-07-09 | 2013-10-08 | Elan Pharmaceuticals, Inc. | Methods of inhibiting amyloid toxicity |
| JP2003024080A (ja) * | 2001-07-19 | 2003-01-28 | Univ Tokyo | p53依存性アポトーシス誘導タンパク質、およびアポトーシス調節剤のスクリーニング方法 |
| EP1380290A1 (en) * | 2002-07-09 | 2004-01-14 | Universitair Medisch Centrum Utrecht | Cross-beta structure pathway and its therapeutic relevance |
| US20050142611A1 (en) * | 2002-09-30 | 2005-06-30 | Auburn University | Method of isolation and self-assembly of small protein particles from blood and other biological materials |
| EP1907864A2 (en) * | 2005-07-13 | 2008-04-09 | Crossbeta Biosciences B.V. | METHODS FOR DETERMINING THE EFFECT OF A TREATMENT ON THE CROSS-ß STRUCTURE CONTENT OF A PROTEIN; SELECTION OF TREATMENTS AND USES THEREOF |
| US8114832B2 (en) * | 2005-07-13 | 2012-02-14 | Crossbeta Biosciences B.V. | Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition |
| WO2007008072A2 (en) * | 2005-07-13 | 2007-01-18 | Crossbeta Biosciences B.V. | CROSS-ß STRUCTURE BINDING COMPOUNDS |
| US20070015133A1 (en) * | 2005-07-13 | 2007-01-18 | Umc Utrecht Holding B.V. | Method for detecting and/or removing protein and/or peptide comprising a cross-beta structure from an aqueous solution comprising a protein |
-
2006
- 2006-02-16 EP EP06075355A patent/EP1820806A1/en not_active Withdrawn
-
2007
- 2007-02-16 WO PCT/NL2007/050063 patent/WO2007094668A1/en not_active Ceased
- 2007-02-16 BR BRPI0707848-0A patent/BRPI0707848A2/pt not_active IP Right Cessation
- 2007-02-16 EP EP07715883A patent/EP1996620A1/en not_active Withdrawn
- 2007-02-16 AU AU2007215621A patent/AU2007215621A1/en not_active Abandoned
- 2007-02-16 CN CNA2007800134201A patent/CN101421304A/zh active Pending
- 2007-02-16 CA CA002642828A patent/CA2642828A1/en not_active Abandoned
- 2007-02-16 JP JP2008555179A patent/JP2009529657A/ja active Pending
- 2007-02-16 US US12/224,087 patent/US20090155254A1/en not_active Abandoned
-
2008
- 2008-09-04 ZA ZA200807630A patent/ZA200807630B/xx unknown
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