JP2009526754A5 - - Google Patents
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- JP2009526754A5 JP2009526754A5 JP2008549107A JP2008549107A JP2009526754A5 JP 2009526754 A5 JP2009526754 A5 JP 2009526754A5 JP 2008549107 A JP2008549107 A JP 2008549107A JP 2008549107 A JP2008549107 A JP 2008549107A JP 2009526754 A5 JP2009526754 A5 JP 2009526754A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- agent
- nanostructure
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 239000008194 pharmaceutical composition Substances 0.000 claims 13
- 239000003814 drug Substances 0.000 claims 8
- 229940079593 drug Drugs 0.000 claims 6
- 239000002086 nanomaterial Substances 0.000 claims 6
- 239000008177 pharmaceutical agent Substances 0.000 claims 5
- 239000011162 core material Substances 0.000 claims 4
- 239000012530 fluid Substances 0.000 claims 4
- 239000007788 liquid Substances 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 2
- 230000001413 cellular effect Effects 0.000 claims 2
- 239000000032 diagnostic agent Substances 0.000 claims 2
- 229940039227 diagnostic agent Drugs 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 229930012538 Paclitaxel Natural products 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 239000002872 contrast media Substances 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 239000000122 growth hormone Substances 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 229960001592 paclitaxel Drugs 0.000 claims 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 229940126586 small molecule drug Drugs 0.000 claims 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Claims (13)
- （ａ）有効成分としての少なくとも１つの医薬剤と、
（ｂ）ナノ構造と、液体と
を含み、前記ナノ構造は、前記液体の整列した流体分子によって包まれたナノメートルサイズのコア材料を含み、前記コア材料、および、前記整列した流体分子のエンベロープが定常的な物理的状態にあり、ただし、前記ナノ構造および液体は、前記少なくとも１つの医薬剤のインビボ取り込みを高めるために配合される、医薬組成物。 - 医薬剤は、治療剤、化粧剤または診断剤である、請求項１に記載の医薬組成物。
- 前記医薬剤は、タンパク質薬剤、核酸薬剤、小分子薬剤、細胞性薬剤およびそれらの組合せからなる群より選択される、請求項１に記載の医薬組成物。
- 前記タンパク質薬剤はペプチドである、請求項３に記載の医薬組成物。
- 前記タンパク質薬剤は、酵素、増殖因子、ホルモンおよび抗体からなる群より選択される、請求項３に記載の医薬組成物。
- 前記細胞性薬剤はウイルスである、請求項３に記載の医薬組成物。
- 前記診断剤は造影剤である、請求項２に記載の医薬組成物。
- 前記ナノ構造はヒドロキシアパタイトから配合される、請求項１に記載の医薬組成物。
- 前記治療剤は、皮膚の状態を処置するために選択される、請求項２に記載の医薬組成物。
- 局所用組成物で配合される、請求項１に記載の医薬組成物。
- 医薬剤は、脳の状態を処置または診断するために選択される、請求項１に記載の医薬組成物。
- （ａ）有効成分としてのタキソールと、（ｂ）ナノ構造および液体とを含む医薬組成物であって、前記ナノ構造は、前記液体の整列した流体分子によって包まれたナノメートルサイズのコア材料を含み、前記コア材料、および、前記整列した流体分子のエンベロープが定常的な物理的状態にある、医薬組成物。
- 経口送達のために配合される、請求項１２に記載の医薬組成物。
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75585206P | 2006-01-04 | 2006-01-04 | |
| US75585006P | 2006-01-04 | 2006-01-04 | |
| US75585106P | 2006-01-04 | 2006-01-04 | |
| US11/324,586 US20060177852A1 (en) | 2001-12-12 | 2006-01-04 | Solid-fluid composition |
| PCT/IL2007/000014 WO2007077561A2 (en) | 2006-01-04 | 2007-01-04 | Compositions and methods for enhancing in-vivo uptake of pharmaceutical agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009526754A JP2009526754A (ja) | 2009-07-23 |
| JP2009526754A5 true JP2009526754A5 (ja) | 2010-02-04 |
Family
ID=39735923
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008549107A Abandoned JP2009526754A (ja) | 2006-01-04 | 2007-01-04 | 医薬剤のインビボ取り込みを強化するための組成物および方法 |
| JP2008549106A Abandoned JP2009521949A (ja) | 2006-01-04 | 2007-01-04 | 凍結保護組成物およびその使用方法 |
| JP2008549108A Abandoned JP2009523128A (ja) | 2006-01-04 | 2007-01-04 | 殺菌組成物及びそれを使用する方法 |
| JP2008549109A Abandoned JP2009524600A (ja) | 2006-01-04 | 2007-01-04 | 固液組成物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008549106A Abandoned JP2009521949A (ja) | 2006-01-04 | 2007-01-04 | 凍結保護組成物およびその使用方法 |
| JP2008549108A Abandoned JP2009523128A (ja) | 2006-01-04 | 2007-01-04 | 殺菌組成物及びそれを使用する方法 |
| JP2008549109A Abandoned JP2009524600A (ja) | 2006-01-04 | 2007-01-04 | 固液組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090029340A1 (ja) |
| EP (4) | EP1981987A2 (ja) |
| JP (4) | JP2009526754A (ja) |
| KR (4) | KR20080098600A (ja) |
| AU (4) | AU2007203960A1 (ja) |
| CA (4) | CA2635968A1 (ja) |
| WO (4) | WO2007077562A2 (ja) |
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2007
- 2007-01-04 AU AU2007203960A patent/AU2007203960A1/en not_active Abandoned
- 2007-01-04 AU AU2007203961A patent/AU2007203961A1/en not_active Abandoned
- 2007-01-04 KR KR1020087018947A patent/KR20080098600A/ko not_active Application Discontinuation
- 2007-01-04 WO PCT/IL2007/000015 patent/WO2007077562A2/en active Application Filing
- 2007-01-04 WO PCT/IL2007/000014 patent/WO2007077561A2/en active Application Filing
- 2007-01-04 EP EP07700707A patent/EP1981987A2/en not_active Withdrawn
- 2007-01-04 JP JP2008549107A patent/JP2009526754A/ja not_active Abandoned
- 2007-01-04 WO PCT/IL2007/000013 patent/WO2007077560A2/en active Application Filing
- 2007-01-04 JP JP2008549106A patent/JP2009521949A/ja not_active Abandoned
- 2007-01-04 KR KR1020087018944A patent/KR20080087148A/ko not_active Application Discontinuation
- 2007-01-04 KR KR1020087018946A patent/KR20080090489A/ko not_active Application Discontinuation
- 2007-01-04 AU AU2007203958A patent/AU2007203958A1/en not_active Abandoned
- 2007-01-04 JP JP2008549108A patent/JP2009523128A/ja not_active Abandoned
- 2007-01-04 CA CA002635968A patent/CA2635968A1/en not_active Abandoned
- 2007-01-04 CA CA002635975A patent/CA2635975A1/en not_active Abandoned
- 2007-01-04 EP EP07700709A patent/EP1981989A2/en not_active Withdrawn
- 2007-01-04 AU AU2007203959A patent/AU2007203959A1/en not_active Abandoned
- 2007-01-04 KR KR1020087018945A patent/KR20080098599A/ko not_active Application Discontinuation
- 2007-01-04 EP EP07700708A patent/EP1981988A2/en not_active Withdrawn
- 2007-01-04 CA CA002635976A patent/CA2635976A1/en not_active Abandoned
- 2007-01-04 EP EP07700706A patent/EP1981986A2/en not_active Withdrawn
- 2007-01-04 CA CA002635978A patent/CA2635978A1/en not_active Abandoned
- 2007-01-04 JP JP2008549109A patent/JP2009524600A/ja not_active Abandoned
- 2007-01-04 US US12/087,429 patent/US20090029340A1/en not_active Abandoned
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