JP2009525297A5 - - Google Patents
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- Publication number
- JP2009525297A5 JP2009525297A5 JP2008552751A JP2008552751A JP2009525297A5 JP 2009525297 A5 JP2009525297 A5 JP 2009525297A5 JP 2008552751 A JP2008552751 A JP 2008552751A JP 2008552751 A JP2008552751 A JP 2008552751A JP 2009525297 A5 JP2009525297 A5 JP 2009525297A5
- Authority
- JP
- Japan
- Prior art keywords
- blood composition
- blood
- interleukin
- composition according
- muscle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000008280 blood Substances 0.000 claims 32
- 210000004369 blood Anatomy 0.000 claims 32
- 239000000203 mixture Substances 0.000 claims 28
- 238000000034 method Methods 0.000 claims 17
- 241001465754 Metazoa Species 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 5
- 102000018233 Fibroblast Growth Factor Human genes 0.000 claims 4
- 108050007372 Fibroblast Growth Factor Proteins 0.000 claims 4
- 102000003745 Hepatocyte Growth Factor Human genes 0.000 claims 4
- 108090000100 Hepatocyte Growth Factor Proteins 0.000 claims 4
- 101001076407 Homo sapiens Interleukin-1 receptor antagonist protein Proteins 0.000 claims 4
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 claims 4
- 102000014429 Insulin-like growth factor Human genes 0.000 claims 4
- 229940119178 Interleukin 1 receptor antagonist Drugs 0.000 claims 4
- 102000000589 Interleukin-1 Human genes 0.000 claims 4
- 108010002352 Interleukin-1 Proteins 0.000 claims 4
- 102000051628 Interleukin-1 receptor antagonist Human genes 0.000 claims 4
- 102000003814 Interleukin-10 Human genes 0.000 claims 4
- 108090000174 Interleukin-10 Proteins 0.000 claims 4
- 102000003816 Interleukin-13 Human genes 0.000 claims 4
- 108090000176 Interleukin-13 Proteins 0.000 claims 4
- 102000004388 Interleukin-4 Human genes 0.000 claims 4
- 108090000978 Interleukin-4 Proteins 0.000 claims 4
- 102000004889 Interleukin-6 Human genes 0.000 claims 4
- 108090001005 Interleukin-6 Proteins 0.000 claims 4
- 102000010780 Platelet-Derived Growth Factor Human genes 0.000 claims 4
- 108010038512 Platelet-Derived Growth Factor Proteins 0.000 claims 4
- 102000009618 Transforming Growth Factors Human genes 0.000 claims 4
- 108010009583 Transforming Growth Factors Proteins 0.000 claims 4
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 4
- 230000001143 conditioned effect Effects 0.000 claims 4
- 229940126864 fibroblast growth factor Drugs 0.000 claims 4
- 239000003407 interleukin 1 receptor blocking agent Substances 0.000 claims 4
- 229940076144 interleukin-10 Drugs 0.000 claims 4
- 229940028885 interleukin-4 Drugs 0.000 claims 4
- 229940100601 interleukin-6 Drugs 0.000 claims 4
- 102000003390 tumor necrosis factor Human genes 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 3
- -1 fines Substances 0.000 claims 3
- 210000003205 muscle Anatomy 0.000 claims 3
- 206010028289 Muscle atrophy Diseases 0.000 claims 2
- 208000029578 Muscle disease Diseases 0.000 claims 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- 230000001684 chronic effect Effects 0.000 claims 2
- 239000011521 glass Substances 0.000 claims 2
- 238000011534 incubation Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 206010056340 Diabetic ulcer Diseases 0.000 claims 1
- 201000009273 Endometriosis Diseases 0.000 claims 1
- 206010020751 Hypersensitivity Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 206010049565 Muscle fatigue Diseases 0.000 claims 1
- 206010070521 Muscle hernia Diseases 0.000 claims 1
- 208000029549 Muscle injury Diseases 0.000 claims 1
- 208000021642 Muscular disease Diseases 0.000 claims 1
- 208000000112 Myalgia Diseases 0.000 claims 1
- 201000009053 Neurodermatitis Diseases 0.000 claims 1
- 241001420836 Ophthalmitis Species 0.000 claims 1
- 239000004698 Polyethylene Substances 0.000 claims 1
- 239000004743 Polypropylene Substances 0.000 claims 1
- 239000004793 Polystyrene Substances 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 229910000831 Steel Inorganic materials 0.000 claims 1
- 206010052428 Wound Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 230000007815 allergy Effects 0.000 claims 1
- 230000000735 allogeneic effect Effects 0.000 claims 1
- 239000011805 ball Substances 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 230000003750 conditioning effect Effects 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 230000006735 deficit Effects 0.000 claims 1
- 230000006806 disease prevention Effects 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 210000001808 exosome Anatomy 0.000 claims 1
- 239000000835 fiber Substances 0.000 claims 1
- 210000000987 immune system Anatomy 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 230000007794 irritation Effects 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 229910044991 metal oxide Inorganic materials 0.000 claims 1
- 150000004706 metal oxides Chemical class 0.000 claims 1
- 150000002739 metals Chemical class 0.000 claims 1
- 230000020763 muscle atrophy Effects 0.000 claims 1
- 208000013465 muscle pain Diseases 0.000 claims 1
- 201000000585 muscular atrophy Diseases 0.000 claims 1
- 201000006938 muscular dystrophy Diseases 0.000 claims 1
- 210000001087 myotubule Anatomy 0.000 claims 1
- 210000000653 nervous system Anatomy 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 208000010403 panophthalmitis Diseases 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 230000035699 permeability Effects 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229940124531 pharmaceutical excipient Drugs 0.000 claims 1
- 239000004033 plastic Substances 0.000 claims 1
- 229920003023 plastic Polymers 0.000 claims 1
- 229920000573 polyethylene Polymers 0.000 claims 1
- 229920001155 polypropylene Polymers 0.000 claims 1
- 229920002223 polystyrene Polymers 0.000 claims 1
- 229920000915 polyvinyl chloride Polymers 0.000 claims 1
- 239000004800 polyvinyl chloride Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000010453 quartz Substances 0.000 claims 1
- 230000008929 regeneration Effects 0.000 claims 1
- 238000011069 regeneration method Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 1
- 239000010959 steel Substances 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 210000002435 tendon Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006005016A DE102006005016A1 (de) | 2006-02-03 | 2006-02-03 | Konditionierte Blutzusammensetzung und Verfahren zu deren Herstellung |
| PCT/EP2007/000903 WO2007090569A1 (de) | 2006-02-03 | 2007-02-02 | Konditionierte blutzusammensetzung und verfahren zu deren herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009525297A JP2009525297A (ja) | 2009-07-09 |
| JP2009525297A5 true JP2009525297A5 (https=) | 2010-03-11 |
Family
ID=37965046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008552751A Withdrawn JP2009525297A (ja) | 2006-02-03 | 2007-02-02 | コンディショニング済み血液組成物およびその製造方法 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20090047242A1 (https=) |
| EP (2) | EP1984006B1 (https=) |
| JP (1) | JP2009525297A (https=) |
| KR (1) | KR20080100425A (https=) |
| CN (1) | CN101378768A (https=) |
| AT (1) | ATE446100T1 (https=) |
| AU (1) | AU2007213996A1 (https=) |
| BR (1) | BRPI0707360A2 (https=) |
| CA (1) | CA2640002A1 (https=) |
| CY (1) | CY1109735T1 (https=) |
| DE (2) | DE102006005016A1 (https=) |
| DK (1) | DK1984006T3 (https=) |
| EA (1) | EA014435B1 (https=) |
| ES (1) | ES2335446T3 (https=) |
| HR (1) | HRP20090684T1 (https=) |
| MX (1) | MX2008009807A (https=) |
| PL (1) | PL1984006T3 (https=) |
| PT (1) | PT1984006E (https=) |
| RS (1) | RS51247B (https=) |
| SI (1) | SI1984006T1 (https=) |
| UA (1) | UA90048C2 (https=) |
| WO (1) | WO2007090569A1 (https=) |
| ZA (1) | ZA200805975B (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7832566B2 (en) | 2002-05-24 | 2010-11-16 | Biomet Biologics, Llc | Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles |
| US20060278588A1 (en) | 2002-05-24 | 2006-12-14 | Woodell-May Jennifer E | Apparatus and method for separating and concentrating fluids containing multiple components |
| US8034014B2 (en) | 2007-03-06 | 2011-10-11 | Biomet Biologics, Llc | Angiogenesis initation and growth |
| US20080269762A1 (en) * | 2007-04-25 | 2008-10-30 | Biomet Manufacturing Corp. | Method and device for repair of cartilage defects |
| US8753690B2 (en) * | 2008-02-27 | 2014-06-17 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
| EP2567692B1 (en) | 2008-02-27 | 2016-04-06 | Biomet Biologics, LLC | Use of a device for obtaining interleukin-1 receptor antagonist rich solutions |
| DE102008028684A1 (de) * | 2008-06-17 | 2009-12-24 | Kopetzky, Robert, Dr. | Blutbeutel |
| US8460227B2 (en) | 2008-11-17 | 2013-06-11 | Arthrex, Inc. | Cytokine concentration system |
| CA2757517A1 (en) | 2009-04-07 | 2010-10-21 | Velin-Pharma A/S | Method and device for treatment of conditions associated with inflammation or undesirable activation of the immune system |
| US20110052561A1 (en) * | 2009-08-27 | 2011-03-03 | Biomet Biologics,LLC | Osteolysis treatment |
| US9763875B2 (en) | 2009-08-27 | 2017-09-19 | Biomet Biologics, Llc | Implantable device for production of interleukin-1 receptor antagonist |
| AU2010294197C9 (en) | 2009-09-10 | 2018-09-13 | Velin-Pharma A/S | Method for the preparation of micro-RNA and its therapeutic application |
| DE202009017772U1 (de) | 2009-12-10 | 2011-04-21 | Orthogen Ag | Kombinationspräparate mit Cytokin-Antagonist und Corticosteroid |
| AU2011296356B2 (en) | 2010-09-03 | 2015-07-09 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
| DE102010042356A1 (de) * | 2010-10-12 | 2012-04-12 | Henke-Sass, Wolf Gmbh | Behälter für die Herstellung einer konditionierten Blutzusammensetzung |
| US9011846B2 (en) | 2011-05-02 | 2015-04-21 | Biomet Biologics, Llc | Thrombin isolated from blood and blood fractions |
| US9205110B2 (en) | 2012-07-18 | 2015-12-08 | Arthrex, Inc. | Enhanced autologous growth factor production and delivery system |
| DE102012019088A1 (de) * | 2012-09-28 | 2014-04-03 | Orthogen Ag | Antibakterielle Arzneimittelpräparate |
| CA2900971C (en) | 2013-02-12 | 2023-08-08 | Lacerta Technologies Inc. | Serum fraction of platelet-rich fibrin |
| US9758806B2 (en) | 2013-03-15 | 2017-09-12 | Biomet Biologics, Llc | Acellular compositions for treating inflammatory disorders |
| US20140271589A1 (en) | 2013-03-15 | 2014-09-18 | Biomet Biologics, Llc | Treatment of collagen defects using protein solutions |
| US9878011B2 (en) | 2013-03-15 | 2018-01-30 | Biomet Biologics, Llc | Treatment of inflammatory respiratory disease using biological solutions |
| US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
| US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
| US10143725B2 (en) | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
| US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
| EP2829278A1 (de) * | 2013-07-23 | 2015-01-28 | Scientific BioTech GmbH | Serum zur Behnandlung von Krankheiten |
| US9833474B2 (en) | 2013-11-26 | 2017-12-05 | Biomet Biologies, LLC | Methods of mediating macrophage phenotypes |
| WO2015085348A1 (en) * | 2013-12-09 | 2015-06-18 | Cytokine Medical Australia Pty Ltd | Apparatus for producing therapeutically active proteins in blood and uses thereof |
| US10441635B2 (en) | 2014-11-10 | 2019-10-15 | Biomet Biologics, Llc | Methods of treating pain using protein solutions |
| US9763800B2 (en) | 2015-03-18 | 2017-09-19 | Biomet C. V. | Implant configured for hammertoe and small bone fixation |
| EA201890841A1 (ru) * | 2016-08-17 | 2018-09-28 | Ортоген Аг | Фармацевтический препарат против старения |
| EP3613424A1 (en) | 2018-08-23 | 2020-02-26 | Orthogen AG | Novel methods for the production of pharmaceutical agents |
| DE102021124752A1 (de) | 2021-09-24 | 2023-03-30 | Ad Lentus GmbH | Autologes Therapeutikum und Verfahren zur Herstellung desselben |
| CN114146096B (zh) * | 2021-11-25 | 2024-04-02 | 成都清科生物科技有限公司 | 一种富含细胞因子的条件血清的制备方法及应用 |
| WO2024237773A1 (ru) * | 2023-05-15 | 2024-11-21 | Роман ЮХТ | Способ получения кондиционированной композиции крови для лечения заболеваний |
| JP7624256B1 (ja) | 2024-01-26 | 2025-01-30 | 万里 坂井 | 医薬組成物及びその製造方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4244437A1 (de) * | 1992-12-29 | 1994-07-28 | Horst Dr Med Kief | Verfahren zur Gewinnung körpereigener Zytokine |
| DE19903876B4 (de) * | 1999-02-01 | 2006-09-28 | Orthogen Gentechnologie Gmbh | Verfahren zur in-vitro-Bildung und Anreicherung von Interleukin-1 Rezeptor-Antagonisten |
| US20020081324A1 (en) * | 2002-01-22 | 2002-06-27 | Twine Rebecca Wright | Method of treating aging skin and wrinkles using a combination of growth factors that is commercially prepared or derived from one's own blood |
-
2006
- 2006-02-03 DE DE102006005016A patent/DE102006005016A1/de not_active Withdrawn
-
2007
- 2007-02-02 HR HR20090684T patent/HRP20090684T1/hr unknown
- 2007-02-02 ES ES07711428T patent/ES2335446T3/es active Active
- 2007-02-02 JP JP2008552751A patent/JP2009525297A/ja not_active Withdrawn
- 2007-02-02 CN CNA2007800044614A patent/CN101378768A/zh active Pending
- 2007-02-02 EP EP07711428A patent/EP1984006B1/de not_active Revoked
- 2007-02-02 EP EP09013177A patent/EP2156841A1/de not_active Withdrawn
- 2007-02-02 SI SI200730130T patent/SI1984006T1/sl unknown
- 2007-02-02 BR BRPI0707360-7A patent/BRPI0707360A2/pt not_active IP Right Cessation
- 2007-02-02 PT PT07711428T patent/PT1984006E/pt unknown
- 2007-02-02 US US12/162,022 patent/US20090047242A1/en not_active Abandoned
- 2007-02-02 DK DK07711428.8T patent/DK1984006T3/da active
- 2007-02-02 CA CA002640002A patent/CA2640002A1/en not_active Abandoned
- 2007-02-02 MX MX2008009807A patent/MX2008009807A/es not_active Application Discontinuation
- 2007-02-02 AU AU2007213996A patent/AU2007213996A1/en not_active Abandoned
- 2007-02-02 EA EA200870222A patent/EA014435B1/ru not_active IP Right Cessation
- 2007-02-02 ZA ZA200805975A patent/ZA200805975B/xx unknown
- 2007-02-02 PL PL07711428T patent/PL1984006T3/pl unknown
- 2007-02-02 DE DE502007001793T patent/DE502007001793D1/de active Active
- 2007-02-02 WO PCT/EP2007/000903 patent/WO2007090569A1/de not_active Ceased
- 2007-02-02 UA UAA200810851A patent/UA90048C2/ru unknown
- 2007-02-02 RS RSP-2010/0012A patent/RS51247B/sr unknown
- 2007-02-02 KR KR1020087018622A patent/KR20080100425A/ko not_active Ceased
- 2007-02-02 AT AT07711428T patent/ATE446100T1/de active
-
2010
- 2010-01-15 CY CY20101100046T patent/CY1109735T1/el unknown
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