JP2009519053A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009519053A5 JP2009519053A5 JP2008544536A JP2008544536A JP2009519053A5 JP 2009519053 A5 JP2009519053 A5 JP 2009519053A5 JP 2008544536 A JP2008544536 A JP 2008544536A JP 2008544536 A JP2008544536 A JP 2008544536A JP 2009519053 A5 JP2009519053 A5 JP 2009519053A5
- Authority
- JP
- Japan
- Prior art keywords
- analyte
- light
- fluorophore
- quencher
- boronic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012491 analyte Substances 0.000 claims 20
- 229920000642 polymer Polymers 0.000 claims 7
- 239000000178 monomer Substances 0.000 claims 6
- 239000000126 substance Substances 0.000 claims 5
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 claims 4
- 125000005620 boronic acid group Chemical group 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical group CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 3
- 239000000975 dye Substances 0.000 claims 3
- STVZJERGLQHEKB-UHFFFAOYSA-N ethylene glycol dimethacrylate Chemical compound CC(=C)C(=O)OCCOC(=O)C(C)=C STVZJERGLQHEKB-UHFFFAOYSA-N 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- ZIUHHBKFKCYYJD-UHFFFAOYSA-N n,n'-methylenebisacrylamide Chemical compound C=CC(=O)NCNC(=O)C=C ZIUHHBKFKCYYJD-UHFFFAOYSA-N 0.000 claims 3
- -1 pyranine sulfonic acid derivative Chemical class 0.000 claims 3
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- DAKWPKUUDNSNPN-UHFFFAOYSA-N Trimethylolpropane triacrylate Chemical compound C=CC(=O)OCC(CC)(COC(=O)C=C)COC(=O)C=C DAKWPKUUDNSNPN-UHFFFAOYSA-N 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 239000002168 alkylating agent Substances 0.000 claims 2
- 229940100198 alkylating agent Drugs 0.000 claims 2
- 235000019270 ammonium chloride Nutrition 0.000 claims 2
- BBEAQIROQSPTKN-UHFFFAOYSA-N antipyrene Natural products C1=CC=C2C=CC3=CC=CC4=CC=C1C2=C43 BBEAQIROQSPTKN-UHFFFAOYSA-N 0.000 claims 2
- HBWDWGMBZIFBQE-UHFFFAOYSA-N benzylboronic acid Chemical compound OB(O)CC1=CC=CC=C1 HBWDWGMBZIFBQE-UHFFFAOYSA-N 0.000 claims 2
- 125000001246 bromo group Chemical group Br* 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 230000002596 correlated effect Effects 0.000 claims 2
- GVEPBJHOBDJJJI-UHFFFAOYSA-N fluoranthrene Natural products C1=CC(C2=CC=CC=C22)=C3C2=CC=CC3=C1 GVEPBJHOBDJJJI-UHFFFAOYSA-N 0.000 claims 2
- 239000000017 hydrogel Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- WFKDPJRCBCBQNT-UHFFFAOYSA-N n,2-dimethylprop-2-enamide Chemical compound CNC(=O)C(C)=C WFKDPJRCBCBQNT-UHFFFAOYSA-N 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 150000003220 pyrenes Chemical class 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 229940096522 trimethylolpropane triacrylate Drugs 0.000 claims 2
- 229940044192 2-hydroxyethyl methacrylate Drugs 0.000 claims 1
- KFNGWPXYNSJXOP-UHFFFAOYSA-N 3-(2-methylprop-2-enoyloxy)propane-1-sulfonic acid Chemical compound CC(=C)C(=O)OCCCS(O)(=O)=O KFNGWPXYNSJXOP-UHFFFAOYSA-N 0.000 claims 1
- MSQCQZMTRWHMFQ-UHFFFAOYSA-N 3-(2-methylprop-2-enoyloxy)propane-1-sulfonic acid;sodium Chemical compound [Na].CC(=C)C(=O)OCCCS(O)(=O)=O MSQCQZMTRWHMFQ-UHFFFAOYSA-N 0.000 claims 1
- IHKHBKOJBAXLDY-UHFFFAOYSA-M 3-aminopropyl-dimethyl-(3-methyl-2-oxobut-3-enyl)azanium;chloride Chemical compound [Cl-].CC(=C)C(=O)C[N+](C)(C)CCCN IHKHBKOJBAXLDY-UHFFFAOYSA-M 0.000 claims 1
- ROFVEXUMMXZLPA-UHFFFAOYSA-N Bipyridyl Chemical group N1=CC=CC=C1C1=CC=CC=N1 ROFVEXUMMXZLPA-UHFFFAOYSA-N 0.000 claims 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- 102100026735 Coagulation factor VIII Human genes 0.000 claims 1
- 239000004971 Cross linker Substances 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- NJSSICCENMLTKO-HRCBOCMUSA-N [(1r,2s,4r,5r)-3-hydroxy-4-(4-methylphenyl)sulfonyloxy-6,8-dioxabicyclo[3.2.1]octan-2-yl] 4-methylbenzenesulfonate Chemical compound C1=CC(C)=CC=C1S(=O)(=O)O[C@H]1C(O)[C@@H](OS(=O)(=O)C=2C=CC(C)=CC=2)[C@@H]2OC[C@H]1O2 NJSSICCENMLTKO-HRCBOCMUSA-N 0.000 claims 1
- 150000001543 aryl boronic acids Chemical class 0.000 claims 1
- 230000005540 biological transmission Effects 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 239000000460 chlorine Chemical group 0.000 claims 1
- 229910052801 chlorine Chemical group 0.000 claims 1
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000004020 conductor Substances 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 239000003431 cross linking reagent Substances 0.000 claims 1
- 230000005284 excitation Effects 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 230000001678 irradiating effect Effects 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 239000002243 precursor Substances 0.000 claims 1
- KXXXUIKPSVVSAW-UHFFFAOYSA-K pyranine Chemical compound [Na+].[Na+].[Na+].C1=C2C(O)=CC(S([O-])(=O)=O)=C(C=C3)C2=C2C3=C(S([O-])(=O)=O)C=C(S([O-])(=O)=O)C2=C1 KXXXUIKPSVVSAW-UHFFFAOYSA-K 0.000 claims 1
- 239000002096 quantum dot Substances 0.000 claims 1
- UZNHKBFIBYXPDV-UHFFFAOYSA-N trimethyl-[3-(2-methylprop-2-enoylamino)propyl]azanium;chloride Chemical compound [Cl-].CC(=C)C(=O)NCCC[N+](C)(C)C UZNHKBFIBYXPDV-UHFFFAOYSA-N 0.000 claims 1
- 229910052724 xenon Inorganic materials 0.000 claims 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/296,898 US7470420B2 (en) | 2000-12-05 | 2005-12-07 | Optical determination of glucose utilizing boronic acid adducts |
| PCT/US2006/046895 WO2007067743A2 (en) | 2005-12-07 | 2006-12-07 | Optical determination of glucose utilizing boronic acid adducts-ii |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012180379A Division JP5476638B2 (ja) | 2005-12-07 | 2012-08-16 | ボロン酸付加体‐ＩＩ（ＢｒｏｎｉｃＡｃｉｄＡｄｄｕｃｔｓ−ＩＩ）を使用したグルコースの光学的決定 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009519053A JP2009519053A (ja) | 2009-05-14 |
| JP2009519053A5 true JP2009519053A5 (https=) | 2010-01-28 |
Family
ID=38123527
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008544536A Pending JP2009519053A (ja) | 2005-12-07 | 2006-12-07 | ボロン酸付加体‐ＩＩ（ＢｒｏｎｉｃＡｃｉｄＡｄｄｕｃｔｓ−ＩＩ）を使用したグルコースの光学的決定 |
| JP2012180379A Expired - Fee Related JP5476638B2 (ja) | 2005-12-07 | 2012-08-16 | ボロン酸付加体‐ＩＩ（ＢｒｏｎｉｃＡｃｉｄＡｄｄｕｃｔｓ−ＩＩ）を使用したグルコースの光学的決定 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012180379A Expired - Fee Related JP5476638B2 (ja) | 2005-12-07 | 2012-08-16 | ボロン酸付加体‐ＩＩ（ＢｒｏｎｉｃＡｃｉｄＡｄｄｕｃｔｓ−ＩＩ）を使用したグルコースの光学的決定 |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US7470420B2 (https=) |
| EP (2) | EP1960779B1 (https=) |
| JP (2) | JP2009519053A (https=) |
| AT (1) | ATE479094T1 (https=) |
| AU (1) | AU2006321854A1 (https=) |
| CA (1) | CA2630790A1 (https=) |
| DE (1) | DE602006016478D1 (https=) |
| WO (1) | WO2007067743A2 (https=) |
Families Citing this family (103)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7470420B2 (en) * | 2000-12-05 | 2008-12-30 | The Regents Of The University Of California | Optical determination of glucose utilizing boronic acid adducts |
| JP5159778B2 (ja) * | 2006-07-25 | 2013-03-13 | グルメトリックス，インコーポレイテッド | グルコース検知における使用のための蛍光色素 |
| US8114662B2 (en) | 2006-07-31 | 2012-02-14 | The Charles Stark Draper Laboratory, Inc. | Ion-selective quantum dots |
| US20080044879A1 (en) * | 2006-08-17 | 2008-02-21 | The Charles Stark Draper Laboratory, Inc. | Systems and methods of voltage-gated ion channel assays |
| US7939664B2 (en) | 2007-05-01 | 2011-05-10 | Glumetrics Inc. | Pyridinium boronic acid quenchers for use in analyte sensors |
| US8738107B2 (en) * | 2007-05-10 | 2014-05-27 | Medtronic Minimed, Inc. | Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement |
| CA2677009A1 (en) * | 2007-02-06 | 2008-08-14 | Glumetrics, Inc. | Optical systems and methods for rationmetric measurement of blood glucose concentration |
| US7751863B2 (en) | 2007-02-06 | 2010-07-06 | Glumetrics, Inc. | Optical determination of ph and glucose |
| JP2010527010A (ja) * | 2007-05-10 | 2010-08-05 | グルメトリクス、 インク． | 被分析物センサーを較正する装置および方法 |
| US8404396B2 (en) | 2007-05-14 | 2013-03-26 | Brigham Young University | Fuel cell and method for generating electric power |
| EP2171471B1 (en) * | 2007-06-08 | 2015-11-18 | The Charles Stark Draper Laboratory, Inc. | Sensors for the detection of diols and carbohydrates using boronic acid chelators for glucose |
| DK2222686T3 (en) * | 2007-07-11 | 2015-09-21 | Medtronic Minimed Inc | Polyviologenboronsyredeaktivatorer for use in analytsensorer |
| EP2181160B1 (en) * | 2007-08-06 | 2016-05-11 | Medtronic Minimed, Inc. | Hpts-mono cys-ma polymerizable fluorescent dyes for use in analyte sensors |
| US7601950B2 (en) * | 2007-09-25 | 2009-10-13 | Baker Hughes Incorporated | System and method for downhole optical analysis |
| US8263358B2 (en) | 2007-10-15 | 2012-09-11 | The Charles Stark Draper Laboratory, Inc. | Intracellular nanosensors and methods for their introduction into cells |
| EP2217316A4 (en) * | 2007-11-21 | 2013-01-16 | Glumetrics Inc | USE OF AN INTRAVASCULAR EQUILIBRIUM SENSOR FOR CLOSE GLYCEMIC CONTROL |
| WO2009066287A2 (en) | 2007-11-21 | 2009-05-28 | Medingo Ltd. | Hypodermic optical monitoring of bodily analyte |
| GB0800278D0 (en) * | 2008-01-08 | 2008-02-13 | Glysure Ltd | Surface functionalisation |
| EP2268314A2 (en) * | 2008-03-21 | 2011-01-05 | Adlyfe, Inc. | Use of pyrene to carry peptides across the blood brain barrier |
| US20090274621A1 (en) * | 2008-03-21 | 2009-11-05 | Adlyfe, Inc | Use of pyrene to carry non-peptide agents across the blood brain barrier |
| WO2009129186A2 (en) * | 2008-04-17 | 2009-10-22 | Glumetrics, Inc. | Sensor for percutaneous intravascular deployment without an indwelling cannula |
| US7858512B2 (en) * | 2008-06-26 | 2010-12-28 | Wafer-Level Packaging Portfolio Llc | Semiconductor with bottom-side wrap-around flange contact |
| US8470300B2 (en) * | 2008-09-08 | 2013-06-25 | The Charles Stark Draper Laboratory, Inc. | Coated sensors and methods related thereto |
| GB0906318D0 (en) | 2009-04-09 | 2009-05-20 | Glysure Ltd | Fluorophore and fluorescent sensor compound containing same |
| EP2464485A2 (en) | 2009-08-14 | 2012-06-20 | Saint-Gobain Abrasives, Inc. | Abrasive articles including abrasive particles bonded to an elongated body |
| JP2013506503A (ja) | 2009-09-30 | 2013-02-28 | グルメトリクス， インコーポレイテッド | 抗血栓性コーティングを備えたセンサー |
| WO2011053247A1 (en) * | 2009-10-29 | 2011-05-05 | Agency For Science, Technology And Research | Method for the detection of an analyte by surface enhanced raman spectroscopy (sers) |
| US8467843B2 (en) | 2009-11-04 | 2013-06-18 | Glumetrics, Inc. | Optical sensor configuration for ratiometric correction of blood glucose measurement |
| EP2498763A4 (en) | 2009-11-09 | 2015-10-07 | Spotlight Technology Partners Llc | HYDROGELE ON POLYSACCHARIDBASIS |
| CN102695501A (zh) | 2009-11-09 | 2012-09-26 | 聚光灯技术合伙有限责任公司 | 碎裂水凝胶 |
| US20110152658A1 (en) * | 2009-12-17 | 2011-06-23 | Glumetrics, Inc. | Identification of aberrant measurements of in vivo glucose concentration using temperature |
| JP2013519101A (ja) | 2010-02-08 | 2013-05-23 | グルメトリクス， インコーポレイテッド | 化学センサーの抗酸化剤保護 |
| US9151764B2 (en) * | 2010-02-16 | 2015-10-06 | Lightship Medical Limited | Barrier layer for glucose sensor |
| WO2011113020A1 (en) * | 2010-03-11 | 2011-09-15 | Glumetrics, Inc. | Measurement devices and methods for measuring analyte concentration incorporating temperature and ph correction |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| WO2012021512A2 (en) | 2010-08-10 | 2012-02-16 | Ecole Polytechnique Federale De Lausanne | Erythrocyte-binding therapeutics |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| TWI466990B (zh) | 2010-12-30 | 2015-01-01 | 聖高拜磨料有限公司 | 磨料物品及形成方法 |
| EP2685884B1 (en) | 2011-03-15 | 2020-09-23 | Senseonics, Incorporated | Integrated catalytic protection of oxidation sensitive materials |
| DE102011101207B3 (de) * | 2011-05-11 | 2012-05-10 | Sartorius Stedim Biotech Gmbh | Fluoreszenzfarbstoff für pH-Sensor |
| GB201113435D0 (en) * | 2011-08-03 | 2011-09-21 | Glysure Ltd | Sensor calibration |
| CN102353660B (zh) * | 2011-06-20 | 2013-01-02 | 山西大学 | 一种检测d-果糖的组合物及其制备方法 |
| US9250246B2 (en) | 2011-06-29 | 2016-02-02 | Portland State University | Near-infrared fluorescent dyes with large stokes shifts |
| JP2014525905A (ja) | 2011-06-29 | 2014-10-02 | ジ オレゴン ステイト ボード オブ ハイヤー エデュケーション オン ビハーフ オブ ポートランド ステイト ユニバーシティー | 近赤外フルオロフォアを使用する分析物検出 |
| EP2769226B1 (en) | 2011-07-15 | 2017-05-24 | Medtronic Minimed, Inc. | Combinations of fluorphores and pyridinium boronic acid quenchers for use in analyte sensors |
| WO2013040423A2 (en) | 2011-09-16 | 2013-03-21 | Saint-Gobain Abrasives, Inc. | Abrasive article and method of forming |
| US10352941B2 (en) | 2011-09-27 | 2019-07-16 | Medtronic Minimed, Inc. | Method for functionalizing a porous membrane covering of an optical sensor to facilitate coupling of an antithrom-bogenic agent |
| JP5869680B2 (ja) | 2011-09-29 | 2016-02-24 | サンーゴバン アブレイシブズ，インコーポレイティド | バリア層を有する細長い基板本体に結合した研磨粒子を含む研磨物品及びその形成方法 |
| US9176032B2 (en) | 2011-12-23 | 2015-11-03 | General Electric Company | Methods of analyzing an H and E stained biological sample |
| US8568991B2 (en) * | 2011-12-23 | 2013-10-29 | General Electric Company | Photoactivated chemical bleaching of dyes |
| SG10201609500QA (en) | 2012-02-15 | 2016-12-29 | Ecole Polytech | Erythrocyte-binding therapeutics |
| US9017622B2 (en) | 2012-04-10 | 2015-04-28 | Lightship Medical Limited | Calibrator for a sensor |
| US20130344619A1 (en) | 2012-06-21 | 2013-12-26 | Lightship Medical Limited | Glucose sensor |
| TWI477343B (zh) | 2012-06-29 | 2015-03-21 | Saint Gobain Abrasives Inc | 研磨物品及形成方法 |
| TW201404527A (zh) | 2012-06-29 | 2014-02-01 | 聖高拜磨料有限公司 | 研磨物品及形成方法 |
| TW201402274A (zh) | 2012-06-29 | 2014-01-16 | 聖高拜磨料有限公司 | 研磨物品及形成方法 |
| JP6534616B2 (ja) * | 2012-11-07 | 2019-06-26 | メドトロニック ミニメド インコーポレイテッド | 光検体センサの乾燥挿入および１点ｉｎｖｉｖｏ較正 |
| US9915592B2 (en) | 2013-03-06 | 2018-03-13 | General Electric Company | Methods of analyzing an H and E stained biological sample |
| TW201441355A (zh) | 2013-04-19 | 2014-11-01 | 聖高拜磨料有限公司 | 研磨製品及其形成方法 |
| US20160139020A1 (en) * | 2013-05-16 | 2016-05-19 | L'oreal | Installation and method for determining the diffusion profile of at least one molecule through skin |
| FI126456B (en) * | 2013-08-26 | 2016-12-15 | Kemira Oyj | Method for detecting transparent exopolymers in a water sample |
| US9963556B2 (en) | 2013-09-18 | 2018-05-08 | Senseonics, Incorporated | Critical point drying of hydrogels in analyte sensors |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| KR102717969B1 (ko) | 2014-02-21 | 2024-10-15 | 에꼴 뽈리떼끄닉 뻬데랄 드 로잔느 (으뻬에프엘) | 글리코타겟팅 치료제 |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| US10761053B2 (en) * | 2014-04-23 | 2020-09-01 | Terumo Kabushiki Kaisha | Non-enzymatic electrochemical sensor for measuring analytes |
| WO2015188144A2 (en) * | 2014-06-05 | 2015-12-10 | The Regents Of The University Of California | Fluorescence method for sensing chlorinated disaccharides |
| US10488418B2 (en) * | 2014-09-02 | 2019-11-26 | The Regents Of The University Of California | Fluorescence assay for intestinal permeability |
| CN104792755B (zh) * | 2015-04-10 | 2017-12-05 | 山西大学 | 一种检测连翘酯苷a的组合物及其制备方法 |
| TWI664057B (zh) | 2015-06-29 | 2019-07-01 | 美商聖高拜磨料有限公司 | 研磨物品及形成方法 |
| US11484724B2 (en) | 2015-09-30 | 2022-11-01 | Btl Medical Solutions A.S. | Methods and devices for tissue treatment using mechanical stimulation and electromagnetic field |
| US12220380B2 (en) | 2015-09-30 | 2025-02-11 | Btl Medical Solutions A.S. | Methods and devices for tissue treatment using mechanical stimulation and electromagnetic field |
| US9850383B2 (en) | 2016-01-27 | 2017-12-26 | Gene Tools, Llc | Uncharged pyrenyloxy sulfonamide dyes for conjugation with biomolecules |
| CN105606738A (zh) * | 2016-02-05 | 2016-05-25 | 湖北吉和昌化工科技有限公司 | 一种聚二硫二丙烷磺酸钠的高效液相色谱分析方法 |
| US10472563B2 (en) * | 2017-02-16 | 2019-11-12 | Rohm And Haas Electronic Materials Llc | Methods for making improved quantum dot resin formulations |
| US11253579B2 (en) | 2017-06-16 | 2022-02-22 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
| JP7199868B2 (ja) * | 2017-10-10 | 2023-01-06 | キヤノン株式会社 | エレクトロクロミック素子、光学フィルタ、レンズユニット、撮像装置、および、窓材 |
| US11892401B2 (en) | 2018-02-13 | 2024-02-06 | The Board Of Trustees Of The Leland Stanford Junior University | Boronic acid appended naphthyl-pyridinium fluorescent saccharide sensors for early detection of gastrointestinal diseases |
| GB201805226D0 (en) * | 2018-03-29 | 2018-05-16 | Univ Dublin City | Boronic Acid Derivatives For Sugar-sensing Hydrogels |
| EA202092723A1 (ru) | 2018-05-09 | 2021-04-09 | Зе Юниверсити Оф Чикаго | Композиции и способы, касающиеся иммунной толерантности |
| EP3876830B1 (en) | 2018-11-11 | 2025-06-25 | Biobeat Technologies Ltd | Wearable apparatus and method for monitoring medical properties |
| WO2020247662A1 (en) * | 2019-06-04 | 2020-12-10 | The Regents Of The University Of California | Diboronic acid compounds and methods of making and using thereof |
| JP7834341B2 (ja) * | 2019-07-31 | 2026-03-24 | シーエス ファーマシューティカルズ エルエルシー | グルコース調節型立体配座スイッチを有するインスリン類似体 |
| CN110562954B (zh) * | 2019-08-02 | 2022-09-30 | 安徽师范大学 | 一种荧光碳点探针的制备方法及在检测Fe2+的应用 |
| JP7595943B2 (ja) | 2019-09-10 | 2024-12-09 | 国立大学法人 東京大学 | 味覚成分検出用センサ材料及び検出方法 |
| US10813578B1 (en) | 2019-12-26 | 2020-10-27 | Biobeat Technologies Ltd. | Sensor device for optical measurement of biological properties |
| US11760170B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Olfaction sensor preservation systems and methods |
| US11932080B2 (en) | 2020-08-20 | 2024-03-19 | Denso International America, Inc. | Diagnostic and recirculation control systems and methods |
| US11881093B2 (en) | 2020-08-20 | 2024-01-23 | Denso International America, Inc. | Systems and methods for identifying smoking in vehicles |
| US12017506B2 (en) | 2020-08-20 | 2024-06-25 | Denso International America, Inc. | Passenger cabin air control systems and methods |
| US11760169B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Particulate control systems and methods for olfaction sensors |
| US11813926B2 (en) | 2020-08-20 | 2023-11-14 | Denso International America, Inc. | Binding agent and olfaction sensor |
| US11828210B2 (en) | 2020-08-20 | 2023-11-28 | Denso International America, Inc. | Diagnostic systems and methods of vehicles using olfaction |
| US12251991B2 (en) | 2020-08-20 | 2025-03-18 | Denso International America, Inc. | Humidity control for olfaction sensors |
| US12269315B2 (en) | 2020-08-20 | 2025-04-08 | Denso International America, Inc. | Systems and methods for measuring and managing odor brought into rental vehicles |
| US11636870B2 (en) | 2020-08-20 | 2023-04-25 | Denso International America, Inc. | Smoking cessation systems and methods |
| US12377711B2 (en) | 2020-08-20 | 2025-08-05 | Denso International America, Inc. | Vehicle feature control systems and methods based on smoking |
| US12377173B2 (en) * | 2021-05-14 | 2025-08-05 | Duke University | Compositions comprising hyperpolarized probes for H2O2 sensing and methods of using same |
| CN113552068A (zh) * | 2021-08-02 | 2021-10-26 | 天津中新药业集团股份有限公司中新制药厂 | 一种异喹啉生物碱的快速精准检测方法、应用及试剂盒 |
| CN116554510A (zh) * | 2023-05-10 | 2023-08-08 | 天津市胸科医院 | 一种碘基纳米造影剂的制备方法 |
| CN116514781B (zh) * | 2023-05-11 | 2025-11-28 | 温州医科大学附属第一医院 | 一种以烯基吲哚为母核的荧光染料及其制备和应用 |
| CN119804403B (zh) * | 2024-12-26 | 2025-08-08 | 中原纳米酶实验室 | 一种基于CoOOH纳米片负载Au纳米簇材料的偶氮二甲酰胺比率荧光检测方法 |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US479873A (en) | 1892-08-02 | doherty | ||
| US4659817A (en) * | 1981-05-01 | 1987-04-21 | The Children's Medical Center Corporation | Reporter compounds containing boron |
| US4586518A (en) | 1984-08-06 | 1986-05-06 | Dow Corning Corporation | Hair setting method using aminoalkyl substituted polydiorganosiloxane |
| US4798738A (en) | 1986-10-10 | 1989-01-17 | Cardiovascular Devices, Inc. | Micro sensor |
| AT385755B (de) * | 1986-06-13 | 1988-05-10 | Koller Ernst | Verfahren zur herstellung von neuen pyrensulfonsaeurederivaten |
| US4886338A (en) * | 1986-10-10 | 1989-12-12 | Minnesota Mining And Manufacturing Company | Optical fiber event sensor |
| AT390517B (de) * | 1988-08-04 | 1990-05-25 | Avl Verbrennungskraft Messtech | Optischer sensor und verfahren zu dessen herstellung |
| NO890029D0 (no) * | 1989-01-04 | 1989-01-04 | Axis Research | Nye modifiserte peptider og proteiner for in vitro diagnoser (diabetes). |
| US5039491A (en) * | 1989-01-27 | 1991-08-13 | Metricor, Inc. | Optical oxygen sensor |
| US5232858A (en) * | 1989-04-25 | 1993-08-03 | Avl Medical Instruments Ag | Method for quantitative determination of at least one chemical parameter of a sample medium |
| US5137833A (en) * | 1989-09-21 | 1992-08-11 | Russell Anthony P | Method for detecting polyhydroxyl compounds |
| US5512246A (en) * | 1989-09-21 | 1996-04-30 | Anthony P. Russell | Method and means for detecting polyhydroxyl compounds |
| US6040194A (en) | 1989-12-14 | 2000-03-21 | Sensor Technologies, Inc. | Methods and device for detecting and quantifying substances in body fluids |
| US5342789A (en) * | 1989-12-14 | 1994-08-30 | Sensor Technologies, Inc. | Method and device for detecting and quantifying glucose in body fluids |
| US5077078A (en) * | 1990-03-14 | 1991-12-31 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Surface modification of plastic optical fibers |
| GB9024775D0 (en) | 1990-11-14 | 1991-01-02 | Axis Research | Chemical compounds |
| US5244562A (en) * | 1991-07-31 | 1993-09-14 | Hewlett-Packard Company | Use of templated polymers for analyte-activated microelectronic switching devices |
| JP2960806B2 (ja) * | 1991-09-12 | 1999-10-12 | 科学技術振興事業団 | アリールボロン酸ダイマーから成る糖の認識剤 |
| US5246867A (en) * | 1992-01-17 | 1993-09-21 | University Of Maryland At Baltimore | Determination and quantification of saccharides by luminescence lifetimes and energy transfer |
| US5466798A (en) * | 1992-03-06 | 1995-11-14 | The Regents Of The University Of California | Synthesis of lithium aminoborohydrides and reactions thereof |
| DE4208645A1 (de) | 1992-03-18 | 1993-09-23 | Bayer Ag | Optischer festphasenbiosensor auf basis fluoreszenzfarbstoffmarkierter polyionischer schichten |
| US6256522B1 (en) | 1992-11-23 | 2001-07-03 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Sensors for continuous monitoring of biochemicals and related method |
| GB2284809B (en) * | 1993-11-07 | 1998-04-29 | Japan Res Dev Corp | A fluorescent phenylboronic acid suitable for use in the detection of saccharides |
| US5494798A (en) * | 1993-12-09 | 1996-02-27 | Gerdt; David W. | Fiber optic evanscent wave sensor for immunoassay |
| US5631364A (en) * | 1994-03-31 | 1997-05-20 | Axis Biochemicals Asa | Labelled boronic acid derivatives |
| AU2222495A (en) * | 1994-05-02 | 1995-11-29 | Novartis Ag | Optical sensor system for determining ph values and ionic strengths |
| US5852126A (en) * | 1994-05-02 | 1998-12-22 | Novartis Ag | Polymerisable composition and the use thereof |
| US5605152A (en) * | 1994-07-18 | 1997-02-25 | Minimed Inc. | Optical glucose sensor |
| US5517313A (en) * | 1995-02-21 | 1996-05-14 | Colvin, Jr.; Arthur E. | Fluorescent optical sensor |
| JP2799837B2 (ja) * | 1995-03-03 | 1998-09-21 | 科学技術振興事業団 | ビナフチル基を有するボロン酸化合物 |
| US5786439A (en) * | 1996-10-24 | 1998-07-28 | Minimed Inc. | Hydrophilic, swellable coatings for biosensors |
| US5882494A (en) * | 1995-03-27 | 1999-03-16 | Minimed, Inc. | Polyurethane/polyurea compositions containing silicone for biosensor membranes |
| DE69633573T2 (de) * | 1995-11-22 | 2005-10-06 | Medtronic MiniMed, Inc., Northridge | Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor |
| US6002954A (en) * | 1995-11-22 | 1999-12-14 | The Regents Of The University Of California | Detection of biological molecules using boronate-based chemical amplification and optical sensors |
| US6063637A (en) * | 1995-12-13 | 2000-05-16 | California Institute Of Technology | Sensors for sugars and other metal binding analytes |
| US5894351A (en) * | 1997-05-13 | 1999-04-13 | Colvin, Jr.; Arthur E. | Fluorescence sensing device |
| US6139799A (en) | 1997-12-16 | 2000-10-31 | Optical Sensors Incorporated | Membranes and optical sensors made therewith having improved barrier properties |
| KR100718953B1 (ko) * | 1998-03-11 | 2007-05-16 | 센서즈 포 메드슨 앤드 사이언스 인코포레이티드 | 형광성 란타니드 킬레이트에 의한 검체의 분석 |
| US6485703B1 (en) * | 1998-07-31 | 2002-11-26 | The Texas A&M University System | Compositions and methods for analyte detection |
| WO2000010007A2 (en) * | 1998-08-17 | 2000-02-24 | California Institute Of Technology | Devices and methods for analysis of non-ionic solutes |
| US6304766B1 (en) * | 1998-08-26 | 2001-10-16 | Sensors For Medicine And Science | Optical-based sensing devices, especially for in-situ sensing in humans |
| JP4689825B2 (ja) * | 1998-08-26 | 2011-05-25 | センサーズ・フォー・メデセン・アンド・サイエンス・インコーポレーテッド | 光学式検知装置 |
| US6285807B1 (en) | 1998-11-16 | 2001-09-04 | Trustees Of Tufts College | Fiber optic sensor for long-term analyte measurements in fluids |
| US6304266B1 (en) | 1999-06-14 | 2001-10-16 | Schlumberger Technology Corporation | Method and apparatus for volume rendering |
| KR20010017486A (ko) | 1999-08-12 | 2001-03-05 | 손동준 | 수용성 아조염료와 그의 응용 |
| US6366793B1 (en) * | 1999-09-10 | 2002-04-02 | Beckman Coulter, Inc. | Minimally invasive methods for measuring analtes in vivo |
| WO2001074968A2 (en) | 2000-04-04 | 2001-10-11 | The Regents Of The University Of California | Saccharide sensing molecules having enhanced fluorescent properties |
| US20010034479A1 (en) * | 2000-04-19 | 2001-10-25 | Ring Lawrence S. | Optically based transcutaneous blood gas sensor |
| US6387672B1 (en) * | 2000-12-04 | 2002-05-14 | Beckman Coulter, Inc. | Photo-induced electron transfer fluorescent sensor molecules |
| US6627177B2 (en) * | 2000-12-05 | 2003-09-30 | The Regents Of The University Of California | Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof |
| US6653141B2 (en) * | 2000-12-05 | 2003-11-25 | The Regents Of The University Of California | Polyhydroxyl-substituted organic molecule sensing method and device |
| US7470420B2 (en) * | 2000-12-05 | 2008-12-30 | The Regents Of The University Of California | Optical determination of glucose utilizing boronic acid adducts |
| EP1519678A2 (en) * | 2001-10-02 | 2005-04-06 | Alfred E. Mann Institute for Biomedical Engineering at the University of Southern California | Internal biochemical sensing device |
| US7317111B2 (en) | 2002-09-23 | 2008-01-08 | Aries Associates, Inc. | Green and orange fluorescent labels and their uses |
| US7358094B2 (en) * | 2003-05-01 | 2008-04-15 | Bell Michael L | Sensor system for saccharides |
| US20040259270A1 (en) * | 2003-06-19 | 2004-12-23 | Wolf David E. | System, device and method for exciting a sensor and detecting analyte |
| JP5159778B2 (ja) * | 2006-07-25 | 2013-03-13 | グルメトリックス，インコーポレイテッド | グルコース検知における使用のための蛍光色素 |
| US7939664B2 (en) * | 2007-05-01 | 2011-05-10 | Glumetrics Inc. | Pyridinium boronic acid quenchers for use in analyte sensors |
| CA2677009A1 (en) * | 2007-02-06 | 2008-08-14 | Glumetrics, Inc. | Optical systems and methods for rationmetric measurement of blood glucose concentration |
| DK2222686T3 (en) * | 2007-07-11 | 2015-09-21 | Medtronic Minimed Inc | Polyviologenboronsyredeaktivatorer for use in analytsensorer |
-
2005
- 2005-12-07 US US11/296,898 patent/US7470420B2/en not_active Expired - Lifetime
-
2006
- 2006-12-07 AU AU2006321854A patent/AU2006321854A1/en not_active Abandoned
- 2006-12-07 AT AT06848506T patent/ATE479094T1/de not_active IP Right Cessation
- 2006-12-07 EP EP06848506A patent/EP1960779B1/en not_active Not-in-force
- 2006-12-07 DE DE602006016478T patent/DE602006016478D1/de active Active
- 2006-12-07 CA CA002630790A patent/CA2630790A1/en not_active Abandoned
- 2006-12-07 EP EP10173872A patent/EP2259061A3/en not_active Withdrawn
- 2006-12-07 JP JP2008544536A patent/JP2009519053A/ja active Pending
- 2006-12-07 WO PCT/US2006/046895 patent/WO2007067743A2/en not_active Ceased
-
2008
- 2008-08-08 US US12/189,089 patent/US7968714B2/en not_active Expired - Lifetime
- 2008-08-08 US US12/189,082 patent/US8394357B2/en not_active Expired - Lifetime
- 2008-08-08 US US12/189,094 patent/US8951503B2/en not_active Expired - Lifetime
-
2011
- 2011-06-09 US US13/157,297 patent/US20120009126A1/en not_active Abandoned
-
2012
- 2012-08-16 JP JP2012180379A patent/JP5476638B2/ja not_active Expired - Fee Related
-
2013
- 2013-01-04 US US13/734,815 patent/US20130121925A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009519053A5 (https=) | ||
| JP5767234B2 (ja) | 光学式センサ | |
| JP2010526599A (ja) | 即時血管内グルコース測定のための平衡非消費蛍光センサー | |
| DK2769226T3 (en) | COMBINATIONS OF FLUORPHORES AND PYRIDINIUM BORIC ACID QUENCHERS FOR USE IN ANALYTICAL SENSORS | |
| JP5476638B2 (ja) | ボロン酸付加体‐ＩＩ（ＢｒｏｎｉｃＡｃｉｄＡｄｄｕｃｔｓ−ＩＩ）を使用したグルコースの光学的決定 | |
| JP2010518397A5 (https=) | ||
| US9995683B2 (en) | Apparatus for single-molecule detection | |
| DK2222686T3 (en) | Polyviologenboronsyredeaktivatorer for use in analytsensorer | |
| JP5209424B2 (ja) | 消光剤前駆体組成物 | |
| US11903702B2 (en) | Multi-analyte sensing tissue-integrating sensors | |
| HUT75507A (en) | Polymerisable composition and articles produced from it | |
| WO2008098087A2 (en) | Optical systems and methods for rationmetric measurement of blood glucose concentration | |
| JP2010526599A5 (https=) | ||
| JP2004536279A5 (https=) | ||
| WO2011113020A1 (en) | Measurement devices and methods for measuring analyte concentration incorporating temperature and ph correction | |
| JP6534616B2 (ja) | 光検体センサの乾燥挿入および１点ｉｎｖｉｖｏ較正 | |
| JPH0658880A (ja) | マイクロセンサーコポリマー及びその製造方法 | |
| CN1942764B (zh) | 指示剂分子的非共价固定 | |
| JP2023516202A (ja) | Ｃｏ２検知用ポリマーマトリックス | |
| US11630094B2 (en) | Layers for the detection of oxygen | |
| EP3844241B1 (en) | Hydrogel | |
| US11579093B2 (en) | Optical component | |
| JP2009042096A (ja) | 表面プラズモン増強蛍光測定用プリズム、その製造方法、及び、それを用いた表面プラズモン増強蛍光センサ | |
| WO2013093792A1 (en) | A sensing membrane for sensing parameters of an organic fluid during its flowing in an extracorporeal circuit |