JP2009516654A5 - - Google Patents
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- Publication number
- JP2009516654A5 JP2009516654A5 JP2008540237A JP2008540237A JP2009516654A5 JP 2009516654 A5 JP2009516654 A5 JP 2009516654A5 JP 2008540237 A JP2008540237 A JP 2008540237A JP 2008540237 A JP2008540237 A JP 2008540237A JP 2009516654 A5 JP2009516654 A5 JP 2009516654A5
- Authority
- JP
- Japan
- Prior art keywords
- angiogenic
- peptide fragment
- amino acid
- fragment according
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108010033276 Peptide Fragments Proteins 0.000 claims 15
- 102000007079 Peptide Fragments Human genes 0.000 claims 15
- 230000001772 anti-angiogenic effect Effects 0.000 claims 13
- 239000012634 fragment Substances 0.000 claims 7
- 150000001413 amino acids Chemical class 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 238000006467 substitution reaction Methods 0.000 claims 2
- 238000013270 controlled release Methods 0.000 claims 1
- 239000003405 delayed action preparation Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73547205P | 2005-11-10 | 2005-11-10 | |
| PCT/US2006/043921 WO2007059000A2 (en) | 2005-11-10 | 2006-11-13 | Modulation of angiogenesis by a-beta peptide fragments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009516654A JP2009516654A (ja) | 2009-04-23 |
| JP2009516654A5 true JP2009516654A5 (enExample) | 2010-01-07 |
Family
ID=38049186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008540237A Withdrawn JP2009516654A (ja) | 2005-11-10 | 2006-11-13 | Ａ−ベータペプチドによる血管新生の調節 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8067372B2 (enExample) |
| EP (1) | EP1951750A4 (enExample) |
| JP (1) | JP2009516654A (enExample) |
| KR (1) | KR20080095836A (enExample) |
| CN (1) | CN101558080A (enExample) |
| AU (1) | AU2006315686A1 (enExample) |
| CA (1) | CA2619455A1 (enExample) |
| WO (1) | WO2007059000A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI239847B (en) * | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| US20080050367A1 (en) * | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
| MY139983A (en) * | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
| PL378571A1 (pl) * | 2003-02-01 | 2006-05-02 | Neuralab Limited | Czynna immunizacja dla wytworzenia przeciwciał przeciw rozpuszczalnemu A-ß |
| AR052051A1 (es) | 2004-12-15 | 2007-02-28 | Neuralab Ltd | Anticuerpos ab humanizados usados en mejorar la cognicion |
| JP2009516654A (ja) | 2005-11-10 | 2009-04-23 | ロスキャンプ リサーチ， エルエルシー | Ａ−ベータペプチドによる血管新生の調節 |
| US8784810B2 (en) * | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
| US8003097B2 (en) * | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
| WO2008131298A2 (en) * | 2007-04-18 | 2008-10-30 | Elan Pharma International Limited | Prevention and treatment of cerebral amyloid angiopathy |
| JP5889529B2 (ja) | 2007-07-27 | 2016-03-22 | ヤンセン・サイエンシズ・アイルランド・ユーシー | アミロイド原性疾患の処置 |
| EP2044951A1 (en) | 2007-10-02 | 2009-04-08 | Merz Pharma GmbH & Co. KGaA | The use of substances for the treatment of loss of eyesight in humans with glaucoma and other degenerative eye diseases |
| JO3076B1 (ar) * | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
| WO2009143489A2 (en) * | 2008-05-22 | 2009-11-26 | Archer Pharmaceuticals, Inc. | Modulation of angiogenesis by a-beta peptide fragments |
| US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
| CN107406513B (zh) * | 2014-07-25 | 2022-07-29 | 台湾地区“中央研究院” | 双链分子(bipartite)及其于治疗异常蛋白聚集的用途 |
| CA3004498A1 (en) | 2015-11-09 | 2017-05-18 | Neil R. Cashman | Amyloid beta epitopes and antibodies thereto |
| AU2016354688B2 (en) | 2015-11-09 | 2021-12-16 | The University Of British Columbia | Epitopes in Amyloid beta mid-region and conformationally-selective antibodies thereto |
| CN108350051A (zh) | 2015-11-09 | 2018-07-31 | 英属哥伦比亚大学 | 淀粉样蛋白β中的N-末端表位及其构象选择性抗体 |
| EP3484919A4 (en) | 2016-07-18 | 2020-03-04 | The University of British Columbia | ANTI-BETA-AMYLOID ANTIBODIES |
| US20180125920A1 (en) | 2016-11-09 | 2018-05-10 | The University Of British Columbia | Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions |
| US12286469B2 (en) | 2017-07-18 | 2025-04-29 | The University Of British Columbia | Humanized antibodies binding to amyloid-beta (A-beta) |
| IT202100023357A1 (it) | 2021-09-09 | 2023-03-09 | Cheirontech S R L | Peptidi con attività anti-angiogenica |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3105009A (en) * | 1959-10-30 | 1963-09-24 | Us Rubber Co | Anti-mitotic chemotherapeutic compounds |
| US5780587A (en) | 1990-08-24 | 1998-07-14 | President And Fellows Of Harvard College | Compounds and methods for inhibiting β-protein filament formation and neurotoxicity |
| US5434050A (en) * | 1991-08-13 | 1995-07-18 | Regents Of The University Of Minnesota | Labelled β-amyloid peptide and methods of screening for Alzheimer's disease |
| DK0667959T3 (da) | 1992-10-26 | 2003-12-08 | Elan Pharm Inc | Fremgangsmåder til identificering af inhibitorer af produktionen af beta-amyloidpeptid |
| WO1994012627A1 (en) | 1992-11-25 | 1994-06-09 | Cephalon, Inc. | Transgenic animal model for alzheimer's disease |
| CA2214247C (en) | 1995-03-14 | 2004-02-10 | Praecis Pharmaceuticals Incorporated | Modulators of amyloid aggregation |
| EP0866805A1 (en) * | 1995-12-12 | 1998-09-30 | Karolinska Innovations AB | PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b) |
| US6043283A (en) * | 1996-09-20 | 2000-03-28 | Baylor College Of Medicine | Tyramine compounds and their neuronal effects |
| US5981471A (en) * | 1997-02-06 | 1999-11-09 | Entremed, Inc. | Compositions and methods for inhibiting cellular proliferation |
| AU784312B2 (en) | 1999-11-29 | 2006-03-09 | Bellus Health (International) Limited | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases |
| US6998137B2 (en) | 2000-04-07 | 2006-02-14 | Macromed, Inc. | Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix |
| WO2003014329A2 (en) * | 2001-08-10 | 2003-02-20 | University Of South Florida | Modulation of angiogenesis by a-beta peptides |
| GB0207362D0 (en) | 2002-03-28 | 2002-05-08 | Univ Liverpool | Chemotherapy |
| JP2009516654A (ja) | 2005-11-10 | 2009-04-23 | ロスキャンプ リサーチ， エルエルシー | Ａ−ベータペプチドによる血管新生の調節 |
-
2006
- 2006-11-13 JP JP2008540237A patent/JP2009516654A/ja not_active Withdrawn
- 2006-11-13 KR KR1020087011171A patent/KR20080095836A/ko not_active Withdrawn
- 2006-11-13 AU AU2006315686A patent/AU2006315686A1/en not_active Abandoned
- 2006-11-13 CN CNA2006800413012A patent/CN101558080A/zh active Pending
- 2006-11-13 CA CA002619455A patent/CA2619455A1/en not_active Abandoned
- 2006-11-13 WO PCT/US2006/043921 patent/WO2007059000A2/en not_active Ceased
- 2006-11-13 US US11/598,299 patent/US8067372B2/en active Active
- 2006-11-13 EP EP06837407A patent/EP1951750A4/en not_active Withdrawn
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