JP2009516534A - 呼気試験装置および方法 - Google Patents

呼気試験装置および方法 Download PDF

Info

Publication number
JP2009516534A
JP2009516534A JP2008539609A JP2008539609A JP2009516534A JP 2009516534 A JP2009516534 A JP 2009516534A JP 2008539609 A JP2008539609 A JP 2008539609A JP 2008539609 A JP2008539609 A JP 2008539609A JP 2009516534 A JP2009516534 A JP 2009516534A
Authority
JP
Japan
Prior art keywords
methacetin
breath
liver
derivative
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008539609A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009516534A5 (https=
Inventor
ベン−オレン，イラン
ヘルシュコヴィッツ，アブラハム
カプラン，エリ
イラン，ヤロン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
(2006)
Original Assignee
(2006)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by (2006) filed Critical (2006)
Publication of JP2009516534A publication Critical patent/JP2009516534A/ja
Publication of JP2009516534A5 publication Critical patent/JP2009516534A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1206—Administration of radioactive gases, aerosols or breath tests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1268—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules host-guest, closed hollow molecules, inclusion complexes, e.g. with cyclodextrins, clathrates, cavitates, fullerenes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Nanotechnology (AREA)
  • Atmospheric Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2008539609A 2005-11-11 2006-11-12 呼気試験装置および方法 Pending JP2009516534A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73547905P 2005-11-11 2005-11-11
PCT/IL2006/001296 WO2007054940A2 (en) 2005-11-11 2006-11-12 Breath test device and method

Publications (2)

Publication Number Publication Date
JP2009516534A true JP2009516534A (ja) 2009-04-23
JP2009516534A5 JP2009516534A5 (https=) 2010-01-07

Family

ID=38023667

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008539609A Pending JP2009516534A (ja) 2005-11-11 2006-11-12 呼気試験装置および方法

Country Status (4)

Country Link
US (1) US8622920B2 (https=)
EP (1) EP1960004A4 (https=)
JP (1) JP2009516534A (https=)
WO (1) WO2007054940A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014517261A (ja) * 2011-04-14 2014-07-17 エクサレンズ バイオサイエンス リミテッド 肝細胞癌の診断、予後診断、監視および治療方法
JP2014518518A (ja) * 2011-04-13 2014-07-31 ヒューメディックス ゲーエムベーハー 少なくとも１種の酵素の代謝能を判定する方法
JP2015511009A (ja) * 2012-03-07 2015-04-13 ウィスコンシン アルムニ リサーチ ファンデイション 同位体の比率をモニタリングすることによる、代謝経路の規則的な変動における変化の比率の検出

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2527595T3 (es) 2005-06-25 2015-01-27 Freie Universität Berlin Solución acuosa de metacetina 13C
US8512258B2 (en) * 2005-11-11 2013-08-20 Exalenz Bioscience Ltd. Breath test device and method
DE102006018862A1 (de) * 2006-03-17 2007-09-20 Charité - Universitätsmedizin Berlin Vorrichtung zur spektroskopischen Analyse eines Gases
US9585613B2 (en) * 2009-02-26 2017-03-07 Universite D'angers Diagnosis of liver fibrosis and cirrhosis
DE102009055320B4 (de) 2009-12-24 2011-09-01 Humedics Gmbh Messvorrichtung und Verfahren zur Untersuchung eines Probegases mittels Infrarot-Absorptionsspektroskopie
US8753889B1 (en) * 2010-04-01 2014-06-17 Beverly L. Roeder Methods for diagnosing and treating disease in animals by the analysis of isotopes in elements such as carbon and nitrogen in animal substrate
US20170181686A1 (en) * 2014-04-02 2017-06-29 Exalenz Bioscience Ltd. Breath test for assessing liver disease
CN115267100A (zh) * 2021-04-30 2022-11-01 北京华亘安邦科技有限公司 13c美沙西汀颗粒剂及其制备方法和应用
CN116688160B (zh) * 2023-07-10 2025-07-25 北京华亘安邦科技有限公司 一种13c美沙西汀口崩片及其制备方法与应用
CN116966323B (zh) * 2023-07-10 2026-02-27 北京华亘安邦科技有限公司 一种13c美沙西汀注射用冻干粉针剂及其制备方法与应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11116503A (ja) * 1997-10-06 1999-04-27 Tokyo Gas Co Ltd 肝機能診断剤
JPH11171798A (ja) * 1997-12-11 1999-06-29 Tokyo Gas Co Ltd 肝機能診断剤
JPH11189549A (ja) * 1997-10-21 1999-07-13 Tokyo Gas Co Ltd 肝機能診断剤
JPH11209310A (ja) * 1998-01-16 1999-08-03 Tokyo Gas Co Ltd 肝機能診断剤
JPH11240845A (ja) * 1997-09-11 1999-09-07 Tokyo Gas Co Ltd 肝手術評価用試薬

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59304180D1 (de) * 1992-07-22 1996-11-21 Mannesmann Ag Nichtdispersives Infrarotspektrometer
US5386832A (en) * 1993-06-11 1995-02-07 New England Deaconess Hospital Liver function breath test using aromatic amino acids
US6186958B1 (en) * 1997-02-26 2001-02-13 Oridion Medical Breath test analyzer
USRE38728E1 (en) * 1997-09-11 2005-04-19 Oridion Medical, LTD Breath test analyzer
ES2319344T3 (es) 1997-09-11 2009-05-06 Oridion Breathid Ltd. Analizador de test de aliento.
CA2249173C (en) * 1997-10-06 2008-12-16 Tokyo Gas Co., Ltd. Diagnostic agent for liver function
CA2250485C (en) * 1997-10-21 2008-04-29 Tokyo Gas Co., Ltd. Diagnostic agent for diabetes
US6656127B1 (en) * 1999-06-08 2003-12-02 Oridion Breathid Ltd. Breath test apparatus and methods
US6486474B1 (en) * 1999-08-13 2002-11-26 Regents Of The University Of Minnesota Infrared spectrometer for the measurement of isotopic ratios
GB0106923D0 (en) * 2001-03-20 2001-05-09 Univ Dundee Liver function test
US20040253637A1 (en) * 2001-04-13 2004-12-16 Biosite Incorporated Markers for differential diagnosis and methods of use thereof
JP2005503205A (ja) * 2001-08-23 2005-02-03 オリディオン ブレシド リミティド 胃腸障害の管理
US6778269B2 (en) * 2001-09-04 2004-08-17 Board Of Regents, The University Of Texas System Detecting isotopes and determining isotope ratios using raman spectroscopy
IL148468A (en) * 2002-03-03 2012-12-31 Exalenz Bioscience Ltd Breath collection system
US7490085B2 (en) * 2002-12-18 2009-02-10 Ge Medical Systems Global Technology Company, Llc Computer-assisted data processing system and method incorporating automated learning
US8778299B2 (en) * 2005-01-26 2014-07-15 The Regents Of The University Of Colorado, A Body Corporate Methods for diagnosis and intervention of hepatic disorders
EP1702558A1 (en) * 2005-02-28 2006-09-20 Euro-Celtique S.A. Method and device for the assessment of bowel function
JP2008538275A (ja) * 2005-04-16 2008-10-23 大塚製薬株式会社 呼気試験を用いたチトクロムｐ４５０２ｄ６アイソザイム活性を評価するための方法と組成物
ES2527595T3 (es) * 2005-06-25 2015-01-27 Freie Universität Berlin Solución acuosa de metacetina 13C
US8512258B2 (en) * 2005-11-11 2013-08-20 Exalenz Bioscience Ltd. Breath test device and method
US7662105B2 (en) * 2005-12-14 2010-02-16 Cardiac Pacemakers, Inc. Systems and methods for determining respiration metrics

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11240845A (ja) * 1997-09-11 1999-09-07 Tokyo Gas Co Ltd 肝手術評価用試薬
JPH11116503A (ja) * 1997-10-06 1999-04-27 Tokyo Gas Co Ltd 肝機能診断剤
JPH11189549A (ja) * 1997-10-21 1999-07-13 Tokyo Gas Co Ltd 肝機能診断剤
JPH11171798A (ja) * 1997-12-11 1999-06-29 Tokyo Gas Co Ltd 肝機能診断剤
JPH11209310A (ja) * 1998-01-16 1999-08-03 Tokyo Gas Co Ltd 肝機能診断剤

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014518518A (ja) * 2011-04-13 2014-07-31 ヒューメディックス ゲーエムベーハー 少なくとも１種の酵素の代謝能を判定する方法
US9560989B2 (en) 2011-04-13 2017-02-07 Humedics Gmbh Method for determining the metabolic capacity of at least one enzyme
JP2014517261A (ja) * 2011-04-14 2014-07-17 エクサレンズ バイオサイエンス リミテッド 肝細胞癌の診断、予後診断、監視および治療方法
JP2015511009A (ja) * 2012-03-07 2015-04-13 ウィスコンシン アルムニ リサーチ ファンデイション 同位体の比率をモニタリングすることによる、代謝経路の規則的な変動における変化の比率の検出

Also Published As

Publication number Publication date
WO2007054940A3 (en) 2009-09-03
US8622920B2 (en) 2014-01-07
EP1960004A2 (en) 2008-08-27
WO2007054940A2 (en) 2007-05-18
US20100036273A1 (en) 2010-02-11
EP1960004A4 (en) 2011-04-20

Similar Documents

Publication Publication Date Title
US20210100493A1 (en) Breath test device and method
CN103764026B (zh) 用于肝细胞癌的诊断、预后、监测和治疗的方法
JP2001507455A (ja) 医薬代謝を検出するための呼気試験
JP2009516534A (ja) 呼気試験装置および方法
KR20040096618A (ko) 폐기능 측정을 위한 13ｃ 표지된 물질의 용도
JP2005503205A (ja) 胃腸障害の管理
RU2116652C1 (ru) Способ выявления поражений эпителия желудка и применение дисахаридов для этой цели
AU2001274585B2 (en) Preparations for measuring gastric pH value and method of measuring gastric pH value by using the same
JP4864083B2 (ja) 胃排出機能及び／又は小腸吸収能を評価するための診断剤
Modak 13C breath tests
JP4683812B2 (ja) ヘリコバクター・ピロリ感染の診断用製剤
WO2016006601A1 (ja) 肝疾患被験者のエネルギー低栄養評価
Mollarasouli et al. Low-molecular-weight biomarkers: types and detection strategies
WO2007119771A1 (ja) ディスペプシア診断検査薬
JP4007659B2 (ja) 糖尿病診断剤
JP4007663B2 (ja) 糖尿病診断剤
JP4007654B2 (ja) 糖尿病診断剤
US20150050744A1 (en) Diagnostic agent and diagnostic method for irritable bowel syndrome induced by abnormal proliferation of enterobacteria
WO2021256506A1 (ja) スクラーゼ活性の測定方法およびスクラーゼ関連疾患の診断方法
JPH11147842A (ja) 糖尿病診断剤
Park et al. Comparison between a new low dose urea capsule test and the conventional UBiT® tablet test for the detection of Helicobacter pylori infection

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20091111

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20091111

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20111005

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120105

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120113

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120206

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120213

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120405

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120719