JP2009514857A5 - - Google Patents
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- Publication number
- JP2009514857A5 JP2009514857A5 JP2008538910A JP2008538910A JP2009514857A5 JP 2009514857 A5 JP2009514857 A5 JP 2009514857A5 JP 2008538910 A JP2008538910 A JP 2008538910A JP 2008538910 A JP2008538910 A JP 2008538910A JP 2009514857 A5 JP2009514857 A5 JP 2009514857A5
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- ibuprofen
- dosage forms
- cyclodextrins
- cyclodextrin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920000858 Cyclodextrin Polymers 0.000 description 9
- 239000000203 mixture Substances 0.000 description 8
- 238000009472 formulation Methods 0.000 description 7
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 description 6
- 229960001680 ibuprofen Drugs 0.000 description 6
- 239000002552 dosage form Substances 0.000 description 5
- 230000000873 masking effect Effects 0.000 description 4
- -1 troches Substances 0.000 description 4
- 229940097362 cyclodextrins Drugs 0.000 description 3
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 3
- 239000003826 tablet Substances 0.000 description 3
- 239000013543 active substance Substances 0.000 description 2
- 239000007935 oral tablet Substances 0.000 description 2
- 150000007524 organic acids Chemical class 0.000 description 2
- 239000007909 solid dosage form Substances 0.000 description 2
- 229920001450 Alpha-Cyclodextrin Polymers 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- 239000001116 FEMA 4028 Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 description 1
- 235000011175 beta-cyclodextrine Nutrition 0.000 description 1
- 229960004853 betadex Drugs 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229940112822 chewing gum Drugs 0.000 description 1
- 235000015218 chewing gum Nutrition 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73312705P | 2005-11-02 | 2005-11-02 | |
| US81041706P | 2006-06-01 | 2006-06-01 | |
| PCT/US2006/041024 WO2007055887A1 (en) | 2005-11-02 | 2006-10-17 | Organoleptically acceptable ibuprofen oral dosage formulations, methods of making and using the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012184203A Division JP2012255018A (ja) | 2005-11-02 | 2012-08-23 | 感覚器官的に許容されるイブプロフェン経口投与用製剤、該製剤の製法並びに使用法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009514857A JP2009514857A (ja) | 2009-04-09 |
| JP2009514857A5 true JP2009514857A5 (enExample) | 2012-10-25 |
Family
ID=38023574
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008538910A Pending JP2009514857A (ja) | 2005-11-02 | 2006-10-17 | 感覚器官的に許容されるイブプロフェン経口投与用製剤、該製剤の製法並びに使用法 |
| JP2012184203A Pending JP2012255018A (ja) | 2005-11-02 | 2012-08-23 | 感覚器官的に許容されるイブプロフェン経口投与用製剤、該製剤の製法並びに使用法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012184203A Pending JP2012255018A (ja) | 2005-11-02 | 2012-08-23 | 感覚器官的に許容されるイブプロフェン経口投与用製剤、該製剤の製法並びに使用法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20070098789A1 (enExample) |
| EP (1) | EP1942877A4 (enExample) |
| JP (2) | JP2009514857A (enExample) |
| KR (1) | KR20080034166A (enExample) |
| CN (1) | CN103622926A (enExample) |
| AR (1) | AR056749A1 (enExample) |
| AU (2) | AU2006312119B2 (enExample) |
| BR (1) | BRPI0618273A2 (enExample) |
| CA (1) | CA2620219A1 (enExample) |
| RU (2) | RU2008116871A (enExample) |
| TW (1) | TW200733954A (enExample) |
| WO (1) | WO2007055887A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0618273A2 (pt) * | 2005-11-02 | 2011-08-23 | Teikoku Pharma Usa Inc | formulações de dosagem oral de ibuprofeno organolepticamente aceitáveis, métodos de produção e uso das mesmas |
| WO2008052033A2 (en) * | 2006-10-25 | 2008-05-02 | Mcneil-Ppc, Inc. | Ibuprofen composition |
| JP5821247B2 (ja) * | 2010-04-07 | 2015-11-24 | 大正製薬株式会社 | イブプロフェンの昇華抑制方法 |
| EP3178470A1 (en) * | 2011-04-11 | 2017-06-14 | Vitux Group AS | Oral pharmaceutical dispersion compositions |
| CN102258490B (zh) * | 2011-07-01 | 2012-10-03 | 中美天津史克制药有限公司 | 布洛芬咀嚼片 |
| US9914968B2 (en) | 2012-09-26 | 2018-03-13 | Cepheid | Honeycomb tube |
| FR2997856B1 (fr) * | 2012-11-14 | 2015-04-24 | Pf Medicament | Pastille medicamenteuse a base d'ibuprofene sodique dihydrate |
| CN103690474B (zh) * | 2013-12-04 | 2015-09-30 | 郑州大明药物科技有限公司 | 布洛芬乳膏的制备方法 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8623557D0 (en) * | 1986-10-01 | 1986-11-05 | Boots Co Plc | Therapeutic agents |
| GB8813682D0 (en) * | 1988-06-09 | 1988-07-13 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions |
| CH677606A5 (enExample) * | 1988-07-12 | 1991-06-14 | Aesculapius Pharma Sa | |
| US4916161A (en) * | 1988-10-25 | 1990-04-10 | Bristol-Myers Squibb | Taste-masking pharmaceutical agents |
| US5055461A (en) * | 1989-02-15 | 1991-10-08 | Richardson-Vicks Inc. | Anesthetic oral compositions and methods of use |
| JPH0426618A (ja) * | 1990-05-21 | 1992-01-29 | Japan Tobacco Inc | トローチ剤 |
| US5024997A (en) * | 1990-06-22 | 1991-06-18 | American Home Products Corporation | Palatable ibuprofen solutions |
| DE69331839T2 (de) * | 1992-01-29 | 2002-12-12 | Takeda Chemical Industries, Ltd. | Schnellösliche Tablette und ihre Herstellung |
| GB9207990D0 (en) * | 1992-04-10 | 1992-05-27 | Smithkline Beecham Plc | Pharmaceutical composition |
| JPH08509725A (ja) * | 1993-04-30 | 1996-10-15 | ザ、プロクター、エンド、ギャンブル、カンパニー | コートされた医薬組成物 |
| US5866162A (en) * | 1993-08-10 | 1999-02-02 | Smithkline Beecham P.L.C. | Pharmaceutical composition containing a drug/β-cyclodextrin complex in combination with an acid-base couple |
| US5616344A (en) * | 1994-06-14 | 1997-04-01 | Fuisz Technologies Ltd. | Apparatus and process for strengthening low density compression dosage units and product therefrom |
| US5560913A (en) * | 1995-01-27 | 1996-10-01 | The Procter & Gamble Company | Pharmaceutical compositions |
| TW442287B (en) * | 1995-06-13 | 2001-06-23 | American Home Produits Corp | Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac) |
| DE69617868T2 (de) * | 1995-10-17 | 2002-06-20 | Reckitt Benckiser Healthcare (Uk) Ltd., Slough | Geschmacksmaskierte wässrige Lösungen enthaltend Ibuprofen und Menthol |
| GB9523833D0 (en) * | 1995-11-22 | 1996-01-24 | Boots Co Plc | Medical treatment |
| US5912007A (en) * | 1996-02-29 | 1999-06-15 | Warner-Lambert Company | Delivery system for the localized administration of medicaments to the upper respiratory tract and methods for preparing and using same |
| AU3444297A (en) * | 1996-07-12 | 1998-02-09 | Novartis Consumer Health S.A. | Oral pharmaceutical combinations of nsaids with terpenoids |
| GB9710521D0 (en) * | 1997-05-22 | 1997-07-16 | Boots Co Plc | Process |
| WO1999055320A1 (en) * | 1998-04-29 | 1999-11-04 | Sumitomo Pharmaceuticals Co., Ltd. | Oral formulation comprising biguanide and an organic acid |
| US20020110581A1 (en) * | 1999-04-06 | 2002-08-15 | Ream Ronald L. | Over-coated product including consumable center and medicament |
| US20050042271A1 (en) * | 1999-11-19 | 2005-02-24 | Xel Herbaceuticals, Inc . | Transdermal delivery system for alkaloids of aconitum species |
| ES2171110B1 (es) * | 2000-03-03 | 2003-06-16 | Aplicaciones Farmacodinamicas | Composicion farmaceutica a base de ibuprofeno y procedimiento para su preparacion. |
| US20020022057A1 (en) * | 2000-08-17 | 2002-02-21 | Battey Alyce S. | Oral delivery of pharmaceuticals via encapsulation |
| KR100762115B1 (ko) * | 2000-08-25 | 2007-10-04 | 코와 가부시키가이샤 | 이부프로펜 캡슐 충전액 및 캡슐 제제 |
| IT1319229B1 (it) * | 2000-10-20 | 2003-09-26 | Savio Macchine Tessili Spa | Dispositivo portarocche perfezionato per avvolgimento di filato conpressione regolata, particolarmente per ritorcitoi a doppia torsione. |
| US20040147606A1 (en) * | 2001-05-25 | 2004-07-29 | Yoichi Onuki | Medicinal compositions |
| US8859028B2 (en) * | 2002-06-14 | 2014-10-14 | Cereal Ingredients, Inc. | Coated food particle and method for making a swirl |
| GB0217382D0 (en) * | 2002-07-26 | 2002-09-04 | Pfizer Ltd | Process for making orally consumable dosage forms |
| US20040071852A1 (en) * | 2002-10-09 | 2004-04-15 | Yael Vodovotz | Compositions and processes for making high soy protein-containing bakery products |
| EP1886582B1 (en) * | 2002-10-11 | 2015-01-14 | Novozymes A/S | Method of preparing a heat-treated product |
| JP4815867B2 (ja) * | 2004-05-11 | 2011-11-16 | 大正製薬株式会社 | 安定化された固形製剤 |
| US20060263475A1 (en) * | 2004-08-25 | 2006-11-23 | Cadbury Adams Usa, Llc. | Center-filled chewing gum composition |
| WO2006067593A1 (en) * | 2004-12-23 | 2006-06-29 | Mcneil-Ppc, Inc. | Orally disintegrating pharmaceutical compositions with sensory cue agents |
| BRPI0618273A2 (pt) * | 2005-11-02 | 2011-08-23 | Teikoku Pharma Usa Inc | formulações de dosagem oral de ibuprofeno organolepticamente aceitáveis, métodos de produção e uso das mesmas |
-
2006
- 2006-10-17 BR BRPI0618273-9A patent/BRPI0618273A2/pt not_active IP Right Cessation
- 2006-10-17 CN CN201310629706.XA patent/CN103622926A/zh active Pending
- 2006-10-17 JP JP2008538910A patent/JP2009514857A/ja active Pending
- 2006-10-17 CA CA002620219A patent/CA2620219A1/en not_active Abandoned
- 2006-10-17 KR KR1020087004052A patent/KR20080034166A/ko not_active Ceased
- 2006-10-17 WO PCT/US2006/041024 patent/WO2007055887A1/en not_active Ceased
- 2006-10-17 RU RU2008116871/15A patent/RU2008116871A/ru unknown
- 2006-10-17 EP EP06817206A patent/EP1942877A4/en not_active Withdrawn
- 2006-10-17 US US11/582,850 patent/US20070098789A1/en not_active Abandoned
- 2006-10-17 AU AU2006312119A patent/AU2006312119B2/en not_active Ceased
- 2006-10-31 AR ARP060104770A patent/AR056749A1/es not_active Application Discontinuation
- 2006-11-01 TW TW095140338A patent/TW200733954A/zh unknown
-
2010
- 2010-05-20 AU AU2010202050A patent/AU2010202050A1/en not_active Abandoned
-
2012
- 2012-08-23 JP JP2012184203A patent/JP2012255018A/ja active Pending
- 2012-09-11 RU RU2012138581/15A patent/RU2012138581A/ru not_active Application Discontinuation
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