RU2008116871A - Органолептически приемлемые пероральные лекарственные формы ибупрофена, способы их приготовления и применения - Google Patents

Органолептически приемлемые пероральные лекарственные формы ибупрофена, способы их приготовления и применения Download PDF

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Publication number
RU2008116871A
RU2008116871A RU2008116871/15A RU2008116871A RU2008116871A RU 2008116871 A RU2008116871 A RU 2008116871A RU 2008116871/15 A RU2008116871/15 A RU 2008116871/15A RU 2008116871 A RU2008116871 A RU 2008116871A RU 2008116871 A RU2008116871 A RU 2008116871A
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RU
Russia
Prior art keywords
dosage form
ibuprofen
acid
form according
masking agent
Prior art date
Application number
RU2008116871/15A
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English (en)
Russian (ru)
Inventor
Тору ХИБИ (US)
Тору Хиби
Original Assignee
ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. (US)
ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК.
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Application filed by ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. (US), ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. filed Critical ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. (US)
Publication of RU2008116871A publication Critical patent/RU2008116871A/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
RU2008116871/15A 2005-11-02 2006-10-17 Органолептически приемлемые пероральные лекарственные формы ибупрофена, способы их приготовления и применения RU2008116871A (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US73312705P 2005-11-02 2005-11-02
US60/733,127 2005-11-02
US81041706P 2006-06-01 2006-06-01
US60/810,417 2006-06-01

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2012138581/15A Division RU2012138581A (ru) 2005-11-02 2012-09-11 Органолептически приемлемая пероральная лекарственная форма ибупрофена и способы ее приготовления и применения

Publications (1)

Publication Number Publication Date
RU2008116871A true RU2008116871A (ru) 2009-12-10

Family

ID=38023574

Family Applications (2)

Application Number Title Priority Date Filing Date
RU2008116871/15A RU2008116871A (ru) 2005-11-02 2006-10-17 Органолептически приемлемые пероральные лекарственные формы ибупрофена, способы их приготовления и применения
RU2012138581/15A RU2012138581A (ru) 2005-11-02 2012-09-11 Органолептически приемлемая пероральная лекарственная форма ибупрофена и способы ее приготовления и применения

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Country Status (12)

Country Link
US (1) US20070098789A1 (enExample)
EP (1) EP1942877A4 (enExample)
JP (2) JP2009514857A (enExample)
KR (1) KR20080034166A (enExample)
CN (1) CN103622926A (enExample)
AR (1) AR056749A1 (enExample)
AU (2) AU2006312119B2 (enExample)
BR (1) BRPI0618273A2 (enExample)
CA (1) CA2620219A1 (enExample)
RU (2) RU2008116871A (enExample)
TW (1) TW200733954A (enExample)
WO (1) WO2007055887A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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RU2567050C2 (ru) * 2011-07-01 2015-10-27 Сино-Американ Тяньцзинь Смитклайн Энд Френч Лаб., Лтд Жевательная таблетка ибупрофена

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WO2008052033A2 (en) * 2006-10-25 2008-05-02 Mcneil-Ppc, Inc. Ibuprofen composition
JP5821247B2 (ja) * 2010-04-07 2015-11-24 大正製薬株式会社 イブプロフェンの昇華抑制方法
EP3178470A1 (en) * 2011-04-11 2017-06-14 Vitux Group AS Oral pharmaceutical dispersion compositions
US9914968B2 (en) 2012-09-26 2018-03-13 Cepheid Honeycomb tube
FR2997856B1 (fr) * 2012-11-14 2015-04-24 Pf Medicament Pastille medicamenteuse a base d'ibuprofene sodique dihydrate
CN103690474B (zh) * 2013-12-04 2015-09-30 郑州大明药物科技有限公司 布洛芬乳膏的制备方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2567050C2 (ru) * 2011-07-01 2015-10-27 Сино-Американ Тяньцзинь Смитклайн Энд Френч Лаб., Лтд Жевательная таблетка ибупрофена

Also Published As

Publication number Publication date
EP1942877A4 (en) 2011-09-14
US20070098789A1 (en) 2007-05-03
KR20080034166A (ko) 2008-04-18
CA2620219A1 (en) 2007-05-18
WO2007055887A1 (en) 2007-05-18
JP2012255018A (ja) 2012-12-27
CN103622926A (zh) 2014-03-12
JP2009514857A (ja) 2009-04-09
BRPI0618273A2 (pt) 2011-08-23
AU2006312119A1 (en) 2007-05-18
AU2010202050A1 (en) 2010-06-10
RU2012138581A (ru) 2014-03-20
EP1942877A1 (en) 2008-07-16
AU2006312119B2 (en) 2010-04-29
AR056749A1 (es) 2007-10-24
TW200733954A (en) 2007-09-16

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